# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_5.hmm.txt
# target sequence database: proteomes/Tetrahymena_thermophila.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_5 [M=309]
Accession: PF01795.18
Description: MraW methylase family
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
3.9e-63 214.4 8.9 4.3e-63 214.3 1.8 2.5 2 tr|Q22Z09|Q22Z09_TETTS 16S rRNA methyltransferase OS=Tetrahy
6.6e-06 26.4 0.1 1.3e-05 25.4 0.0 1.5 2 tr|W7XCF3|W7XCF3_TETTS HemK methyltransferase family protein
0.0064 16.6 0.1 0.012 15.7 0.0 1.5 1 tr|Q239D4|Q239D4_TETTS Cyclopropane-fatty-acyl-phospholipid
------ inclusion threshold ------
0.017 15.2 0.0 0.045 13.8 0.0 1.6 2 tr|W7X2L6|W7X2L6_TETTS 2-methoxy-6-polyprenyl-1,4-benzoquino
0.06 13.4 0.0 0.1 12.7 0.0 1.4 1 tr|I7MAE9|I7MAE9_TETTS UbiE/COQ5 family methyltransferase OS
1.4 8.9 5.3 2.7 8.0 2.4 2.0 2 tr|Q22KB0|Q22KB0_TETTS Anaphase-promoting complex subunit 11
Domain annotation for each sequence (and alignments):
>> tr|Q22Z09|Q22Z09_TETTS 16S rRNA methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_0011
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 3.7 0.8 0.012 55 133 187 .. 17 68 .. 6 85 .. 0.82
2 ! 214.3 1.8 9.5e-67 4.3e-63 3 308 .. 99 410 .. 97 411 .. 0.88
Alignments for each domain:
== domain 1 score: 3.7 bits; conditional E-value: 0.012
-HHHHHHH--HHHHHHHHHHHH--TTHHHHHHHHHHHHHHS---BHHHHHHHHHH CS
Methyltransf_5 133 tAaevlnrlseeeLakilkeygeekfakriakaivekrkkkpiettkelaevikk 187
+++ln+ ++ L + +k+ g e+ +++k++++++k +++++++++ ++
tr|Q22Z09|Q22Z09_TETTS 17 QSSKLLNQQIQYSLFNFIKQEGLENKLSSLSKKVQQEKKGQKLSKVEQMI---QQ 68
46789*********************************999998877654...44 PP
== domain 2 score: 214.3 bits; conditional E-value: 9.5e-67
XX--TTTHHHHHHT--........-TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.....-.....--EEEEES CS
Methyltransf_5 3 eHvpVLlqevvellep........kedgvyiDaTlGaggHsealLeqlselrligidrDksalarakerLkefe.....krltlvkg 76
H+pVL++++ ++l++ +++++++D+TlG++gH++++L++++ l ++g+d D+++l+ ++++k+ +r+++ ++
tr|Q22Z09|Q22Z09_TETTS 99 VHYPVLIDKITQVLQEefyphsssHSEKCLVDCTLGSAGHAKHFLQKFPYLYILGLDLDPRMLQYINDNVKSQLshsdqNRFKTRNE 185
7***********************9**************************************876655554332222355****** PP
-GGGHHHHHHHTTTT.......-EEEEEEE-S--HHHHH-GGG---SSS--BS---S-TTSS-.-HHHHHHH--HHHHHHHHHHHH- CS
Methyltransf_5 77 nfkelkealaeanvt.......kvdgillDLGvSslqldkaerGFsfaedapLDmRmdqsael.tAaevlnrlseeeLakilkeyge 155
nf++++++ + + ++ +i++DLG l+l+++e GFs+ +++ LDmR +qs++ +Aa++ln+ s+ eL +i+++yge
tr|Q22Z09|Q22Z09_TETTS 186 NFTNIDKINLYKIFEeefpsykNFHAIFADLGYNTLHLENSEWGFSYLRNGKLDMRYNQSSQTnSAADILNKASYLELFEIIRQYGE 272
**99988655433223444444************************************998877*********************** PP
-TTHHHHHHHHHHHHHHS---BHHHHHHHHHHHS-------...-TTHHHHHHHHHHHHTHHHHHHHHHHHHHHHEEEEEEEEEEES CS
Methyltransf_5 156 ekfakriakaivekrkkkpiettkelaevikkvvpakekrk.kihpatrvFQAlRIavNdEleeleelleaalellakggrlavisF 241
+ a i++ i ++r+ kp+ettk+++++i + + ++ + + + t+ FQAlRIa N+El +l+ +++++ + l k+g +i+F
tr|Q22Z09|Q22Z09_TETTS 273 DPNADVISQMIIKQRQIKPFETTKDVVDLILEDQSGYSFKGgQYKAITKLFQALRIATNQELTNLQVFMDKIYDKLLKDGLGIIITF 359
******************************99998888665256778**************************************** PP
SHHHHHHHHHHHHHTT-------------------EEEEE.E.E---HHHHHH-GGGTT-EEEEEEE CS
Methyltransf_5 242 hSledrivkkvfkeaskkeevPaglpvaseelkaklklitkkpilpseeeikeNprsrsakLrviek 308
hSle+ iv + +++++++ ++++++ p +e+++N +srsakL ++k
tr|Q22Z09|Q22Z09_TETTS 360 HSLEENIVEQKLRDLKRQ---------------KNIEILQ-MGEKPDINELQKNSKSRSAKLYTFKK 410
***************994...............3344444.3356999**************99987 PP
>> tr|W7XCF3|W7XCF3_TETTS HemK methyltransferase family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.8 0.0 2.3 1e+04 149 176 .. 47 74 .. 28 86 .. 0.68
2 ! 25.4 0.0 3e-09 1.3e-05 9 97 .. 103 196 .. 97 217 .. 0.88
Alignments for each domain:
== domain 1 score: -3.8 bits; conditional E-value: 2.3
HHHHHH--TTHHHHHHHHHHHHHHS--- CS
Methyltransf_5 149 ilkeygeekfakriakaivekrkkkpie 176
++ + + + k+i k ++r+ pi+
tr|W7XCF3|W7XCF3_TETTS 47 MFSNCSSYYYLKQIQKMYFKRRAMMPIQ 74
4555555666677777777777666665 PP
== domain 2 score: 25.4 bits; conditional E-value: 3e-09
THHHHHHT--.-TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.....-...--EEEEES-G.GGHHHHHHHTTT CS
Methyltransf_5 9 lqevvellep.kedgvyiDaTlGaggHsealLeqlselrligidrDksalarakerLkefe...krltlvkgnf.kelkealaeanv 90
l e+v+ l++ k++ ++ +G+g s lL++ s+ + i+id+ k ++ ak++L+ + +rl+l++ + k++++ l++++
tr|W7XCF3|W7XCF3_TETTS 103 LVELVNKLSKqKQKCQFLEIGIGTGAISLSLLKENSQFTGIAIDKQKFCIELAKQNLNLNKidpQRLQLIHLEClKFFQNNLNQNPD 189
4466777765377889****************************************9877655677*****9998**********9* PP
T-EEEEE CS
Methyltransf_5 91 tkvdgil 97
+++d+i+
tr|W7XCF3|W7XCF3_TETTS 190 QQFDFIV 196
****997 PP
>> tr|Q239D4|Q239D4_TETTS Cyclopropane-fatty-acyl-phospholipid synthase OS=Tetrahymena thermophila (strain SB210) OX=31
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.7 0.0 2.8e-06 0.012 24 86 .. 53 115 .. 25 136 .. 0.82
Alignments for each domain:
== domain 1 score: 15.7 bits; conditional E-value: 2.8e-06
EEES--TTSHHHHHHHTT--TT.EEEEEES-HHHHHHHTT.....---EEEEES-GGGHHHHHH CS
Methyltransf_5 24 yiDaTlGaggHsealLeqlsel.rligidrDksalarakerLkefekrltlvkgnfkelkeala 86
+D +G+g ++ ++++++ +++g+d+D++ +++a++ +k++++ +++ +nf el+++ +
tr|Q239D4|Q239D4_TETTS 53 ILDIGIGTGLPLYKIASKFPQNaKILGVDIDENYVKAAQKLFKDKKN-VEIRLQNFYELDAKKE 115
57999999999999*******99*****************8888755.********99987655 PP
>> tr|W7X2L6|W7X2L6_TETTS 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Tetrahymena thermophila (s
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.6 0.0 1 4.6e+03 43 63 .. 133 153 .. 100 175 .. 0.53
2 ? 13.8 0.0 1e-05 0.045 215 258 .. 192 235 .. 176 246 .. 0.85
Alignments for each domain:
== domain 1 score: -2.6 bits; conditional E-value: 1
-TTEEEEEES-HHHHHHHTT. CS
Methyltransf_5 43 selrligidrDksalaraker 63
++l+++ +d+ +s+l++ k+r
tr|W7X2L6|W7X2L6_TETTS 133 KNLKVTVLDINESMLEVGKRR 153
222444444555555444443 PP
== domain 2 score: 13.8 bits; conditional E-value: 1e-05
HHHHHHHHHHHHHHHEEEEEEEEEEESSHHHHHHHHHHHHHTT- CS
Methyltransf_5 215 EleeleelleaalellakggrlavisFhSledrivkkvfkeask 258
++e++l++a ++l+kggrl+++ F +e+ v ++ k+++
tr|W7X2L6|W7X2L6_TETTS 192 NVPRIEKALSEAHRVLKKGGRLMILEFSKVEQFPVSEIYKQYNM 235
56789***************************999999998876 PP
>> tr|I7MAE9|I7MAE9_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.7 0.0 2.3e-05 0.1 21 83 .. 52 114 .. 19 132 .. 0.80
Alignments for each domain:
== domain 1 score: 12.7 bits; conditional E-value: 2.3e-05
T-EEEES--TTSHHHHHHHTT--TT.EEEEEES-HHHHHHHTT.....---EEEEES-GGGHHH CS
Methyltransf_5 21 dgvyiDaTlGaggHsealLeqlsel.rligidrDksalarakerLkefekrltlvkgnfkelke 83
+ +D+ +G+g +++++++ +++gid+D++ + +ak+ ++++ + +++ nf ++++
tr|I7MAE9|I7MAE9_TETTS 52 FKRILDVGVGTGHPLYSIIDRIPKSvQVTGIDIDTNYIPAAKKIFSKHSN-VEIKYMNFYDMEK 114
45678999999888899******999*****************9999976.7776666755544 PP
>> tr|Q22KB0|Q22KB0_TETTS Anaphase-promoting complex subunit 11 RING-H2 finger protein OS=Tetrahymena thermophila (stra
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 8.0 2.4 0.00061 2.7 149 197 .. 20 68 .. 8 78 .. 0.77
2 ? 3.1 0.2 0.018 82 258 301 .. 74 119 .. 57 121 .. 0.66
Alignments for each domain:
== domain 1 score: 8.0 bits; conditional E-value: 0.00061
HHHHHH--TTHHHHHHHHHHHHHHS---BHHHHHHHHHHHS-------. CS
Methyltransf_5 149 ilkeygeekfakriakaivekrkkkpiettkelaevikkvvpakekrkk 197
l + +++++k i +i+e+rk k+i + ++++e+i + +k+ +k
tr|Q22KB0|Q22KB0_TETTS 20 ALIKKQNIRYSKFIYINICEERKIKQIINSQQIQEFILQKRISKDLINK 68
45556799****************************9887666555554 PP
== domain 2 score: 3.1 bits; conditional E-value: 0.018
-----..--------------EEEEE.E.E---HHHHHH-GGGTT- CS
Methyltransf_5 258 kkeev..PaglpvaseelkaklklitkkpilpseeeikeNprsrsa 301
k+ ev + + + + +++ + +i k i+ + e ++N+ s sa
tr|Q22KB0|Q22KB0_TETTS 74 KRFEVkkWNAVALWQWDIEVENCAICKNNIMEPCIECDANQNSNSA 119
333332244555666667778889*********************9 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (309 nodes)
Target sequences: 26971 (16912921 residues searched)
Passed MSV filter: 2464 (0.0913574); expected 539.4 (0.02)
Passed bias filter: 252 (0.00934337); expected 539.4 (0.02)
Passed Vit filter: 22 (0.000815691); expected 27.0 (0.001)
Passed Fwd filter: 6 (0.000222461); expected 0.3 (1e-05)
Initial search space (Z): 26971 [actual number of targets]
Domain search space (domZ): 6 [number of targets reported over threshold]
# CPU time: 0.36u 0.02s 00:00:00.38 Elapsed: 00:00:00.12
# Mc/sec: 43550.77
//
[ok]