# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Methyltransf_5.hmm.txt
# target sequence database:        proteomes/Thermococcus_kodakarensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Methyltransf_5  [M=309]
Accession:   PF01795.18
Description: MraW methylase family
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
     0.0063   13.1   0.0      0.085    9.4   0.0    2.1  2  tr|Q5JDP5|Q5JDP5_THEKO  tRNA/rRNA cytosine-C5-methylase, NOL1
     0.0075   12.9   0.0      0.024   11.2   0.0    1.8  2  tr|Q5JHQ2|Q5JHQ2_THEKO  SAM-dependent methyltransferase, UbiE
     0.0092   12.6   0.0      0.078    9.5   0.0    1.9  2  tr|Q5JFS6|Q5JFS6_THEKO  Predicted SAM-dependent methyltransfe
  ------ inclusion threshold ------
      0.014   12.0   0.0      0.025   11.2   0.0    1.4  1  tr|Q5JEC3|Q5JEC3_THEKO  Predicted DNA methylase OS=Thermococc


Domain annotation for each sequence (and alignments):
>> tr|Q5JDP5|Q5JDP5_THEKO  tRNA/rRNA cytosine-C5-methylase, NOL1/NOP2/Sun family OS=Thermococcus kodakarensis (strain AT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.0   0.00015     0.085      15      80 ..     245     312 ..     238     330 .. 0.81
   2 ?    1.1   0.0      0.05        29     220     256 ..     360     399 ..     355     414 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00015
                             HT---TT-EEEES--TTSHHHHHHHTT--TT.EEEEEES-HHHHHHHTT.....---.EEEEES-GGG CS
          Methyltransf_5  15 llepkedgvyiDaTlGaggHsealLeqlsel.rligidrDksalarakerLkefekr.ltlvkgnfke 80 
                             +l+pk++ + +D     gg + ++ e +++  +++++d D+  ++r ke+Lk+   +  +++k+  ++
  tr|Q5JDP5|Q5JDP5_THEKO 245 VLAPKPGETVVDLAAAPGGKTAHMAELMENRgKIYAFDVDSARIKRMKEVLKRTGVEiAEVIKADGRN 312
                             58899*********************999999********************9876634555555455 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.05
                             HHHHHHHHHHEEEEEEEEEEESSHH...HHHHHHHHHHHT CS
          Methyltransf_5 220 eelleaalellakggrlavisFhSl...edrivkkvfkea 256
                             +el+e+a +ll++ggrl   +   l   ++ +vk++++  
  tr|Q5JDP5|Q5JDP5_THEKO 360 KELMESAWKLLKPGGRLLYSTCSMLpeeNEEVVKWFLERH 399
                             6899************975544333332456777777655 PP

>> tr|Q5JHQ2|Q5JHQ2_THEKO  SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.0   4.2e-05     0.024      16      82 ..      28      98 ..      21     115 .. 0.81
   2 ?   -1.3   0.0      0.28   1.6e+02     215     236 ..     117     138 ..     108     145 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4.2e-05
                            T--......-TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.....---EEEEES-GGGHH CS
          Methyltransf_5 16 lep......kedgvyiDaTlGaggHsealLeqlselrligidrDksalarakerLkefekrltlvkgnfkelk 82
                            lep      k  g  +D   G gg s  lLe l   +++g+d+ + +l++a+e+ ke+e r+++++g  +el 
  tr|Q5JHQ2|Q5JHQ2_THEKO 28 LEPllmkfmKTRGRVLDLACGVGGFS-FLLEDLGF-EVVGLDNSRFMLEKAREFAKEKESRVEFIEGDARELP 98
                            5555555668888999********98.67777765.799**************************99988876 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.28
                             HHHHHHHHHHHHHHHEEEEEEE CS
          Methyltransf_5 215 Eleeleelleaalellakggrl 236
                             E + l ++ +++ ++l++gg++
  tr|Q5JHQ2|Q5JHQ2_THEKO 117 EPQDLAKVFKETARVLKPGGKF 138
                             6678889999999999999997 PP

>> tr|Q5JFS6|Q5JFS6_THEKO  Predicted SAM-dependent methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 /
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.5   0.0   0.00014     0.078      10      81 ..      47     118 ..      44     136 .. 0.85
   2 ?    1.0   0.0     0.054        31     221     242 ..     140     161 ..     136     195 .. 0.77

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00014
                             HHHHHHT---TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.....---EEEEES-GGGH CS
          Methyltransf_5  10 qevvellepkedgvyiDaTlGaggHsealLeqlselrligidrDksalarakerLkefekrltlvkgnfkel 81 
                             ++++e+++++ +g  +D+  G+g+ + ++  +   + ++g+dr +++++ +++   + +k+ ++v+gnf e+
  tr|Q5JFS6|Q5JFS6_THEKO  47 KRLMEMITDEVKGKVLDVGCGTGVLTFKMALKNGVEMVVGVDRKEEVIEFCNRLGDRVTKNAKFVQGNFLEM 118
                             56789999999999***********999988899999**************9977888888********654 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.054
                             HHHHHHHHHEEEEEEEEEEESS CS
          Methyltransf_5 221 elleaalellakggrlavisFh 242
                              +le ale+l++ggr+ v  F 
  tr|Q5JFS6|Q5JFS6_THEKO 140 PFLERALEVLEEGGRVIVGDFD 161
                             5899************997775 PP

>> tr|Q5JEC3|Q5JEC3_THEKO  Predicted DNA methylase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   4.3e-05     0.025      11      98 ..     181     268 ..     175     315 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4.3e-05
                             HHHHHT---TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.....---EEEEES-GGGHHHHHHHTT..TT-EEE CS
          Methyltransf_5  11 evvellepkedgvyiDaTlGaggHsealLeqlselrligidrDksalarakerLkefekrltlvkgnfkelkealaean..vtkvdg 95 
                             +++ +l++  +g ++D   G g   +++   l+ l+++g drD+  +  ak++L+   k+++l ++   e+ +a + ++   +++d+
  tr|Q5JEC3|Q5JEC3_THEKO 181 RIMVNLTEVRKGSFLDPFCGIGTVVQEFV--LQGLTAYGSDRDEGQIRDAKKNLTWLRKEFRLKNSAHLEVCDARKLKKcfRQRFDA 265
                             45666777888999999999999999987..456789************************99999886665555544444667787 PP

                             EEE CS
          Methyltransf_5  96 ill 98 
                             i+ 
  tr|Q5JEC3|Q5JEC3_THEKO 266 IVT 268
                             776 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (309 nodes)
Target sequences:                         2301  (637680 residues searched)
Passed MSV filter:                       109  (0.0473707); expected 46.0 (0.02)
Passed bias filter:                       77  (0.0334637); expected 46.0 (0.02)
Passed Vit filter:                        12  (0.00521512); expected 2.3 (0.001)
Passed Fwd filter:                         4  (0.00173837); expected 0.0 (1e-05)
Initial search space (Z):               2301  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.02
# Mc/sec: 9852.16
//
[ok]