# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Methyltransf_8.hmm.txt
# target sequence database:        proteomes/Anolis_carolinensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Methyltransf_8  [M=219]
Accession:   PF05148.15
Description: Hypothetical methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.6e-06   28.2   0.0    2.3e-06   27.7   0.0    1.2  1  tr|G1KTN7|G1KTN7_ANOCA  Uncharacterized protein OS=Anolis car
    2.5e-05   24.3   0.0    3.6e-05   23.8   0.0    1.3  1  tr|G1KTN5|G1KTN5_ANOCA  Uncharacterized protein OS=Anolis car
    0.00036   20.5   0.0     0.0072   16.2   0.0    2.6  2  tr|H9G6W9|H9G6W9_ANOCA  2-methoxy-6-polyprenyl-1,4-benzoquino
    0.00088   19.2   0.0     0.0023   17.8   0.0    1.6  1  tr|G1K8X1|G1K8X1_ANOCA  NADH:ubiquinone oxidoreductase comple
     0.0054   16.7   0.3      0.012   15.5   0.0    1.7  2  tr|R4GB35|R4GB35_ANOCA  mRNA cap guanine-N7 methyltransferase
  ------ inclusion threshold ------
      0.022   14.7   0.1       0.15   11.9   0.0    2.1  2  tr|R4G9E3|R4G9E3_ANOCA  Arsenite methyltransferase OS=Anolis 


Domain annotation for each sequence (and alignments):
>> tr|G1KTN7|G1KTN7_ANOCA  Uncharacterized protein OS=Anolis carolinensis OX=28377 GN=LOC100557412 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.7   0.0   7.3e-10   2.3e-06     118     173 ..     133     190 ..     118     217 .. 0.87

  Alignments for each domain:
  == domain 1  score: 27.7 bits;  conditional E-value: 7.3e-10
                             --TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEE.EGGG-S-HHHHHHHH CS
          Methyltransf_8 118 ledesvdvavfclslm.gtnladflkeanrvlkvGGllkvae.vksrfesvklfaral 173
                             + d+svdv+v+ l l  + n+++ lke+ r+lk+GG ++  e v s  +s k f +++
  tr|G1KTN7|G1KTN7_ANOCA 133 VSDGSVDVVVCTLVLCsVSNVTTVLKEVLRILKPGGAFFFMEhVASPRSSWKYFWQQV 190
                             579***********97368*****************9876654888888888887765 PP

>> tr|G1KTN5|G1KTN5_ANOCA  Uncharacterized protein OS=Anolis carolinensis OX=28377 GN=LOC100557610 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   1.2e-08   3.6e-05     111     158 ..     130     176 ..     105     194 .. 0.86

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 1.2e-08
                             S-TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEE CS
          Methyltransf_8 111 cdlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkvae 158
                              dl ++P  d svdv+v+ l l  ++n a  l e+ rvl++GG ++  e
  tr|G1KTN5|G1KTN5_ANOCA 130 EDLHQIP--DASVDVVVCTLVLCsVKNTARVLSEVLRVLRPGGAFYFME 176
                             4778887..99**********973689*****************99876 PP

>> tr|H9G6W9|H9G6W9_ANOCA  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Anolis carolinensis OX=283
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   2.3e-06    0.0072     113     159 ..     183     230 ..     173     247 .. 0.84
   2 ?    0.5   0.0      0.16   4.8e+02     156     187 ..     267     298 ..     260     305 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.3e-06
                             TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEEE CS
          Methyltransf_8 113 lakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkvaev 159
                               ++P +d+  d+  + + +  +t + + l+ea+rvlk+GG +   e 
  tr|H9G6W9|H9G6W9_ANOCA 183 AEELPFNDNNFDIYTIAFGIRnVTHIDQALQEAYRVLKPGGRFLCLEF 230
                             5689*********99999985389*****************9887765 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.16
                             EEEEGGG-S-HHHHHHHHHCTTEEEEEEE--S CS
          Methyltransf_8 156 vaevksrfesvklfaraltklGfevkskdlsn 187
                             + e   rf+  + f++ ++  Gf  ++ +  +
  tr|H9G6W9|H9G6W9_ANOCA 267 LVESIRRFPAQEEFKEMIEDAGFLKVHYQNLS 298
                             5666779****************999987665 PP

>> tr|G1K8X1|G1K8X1_ANOCA  NADH:ubiquinone oxidoreductase complex assembly factor 5 OS=Anolis carolinensis OX=28377 GN=N
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   7.6e-07    0.0023      77     154 ..      78     168 ..      71     172 .. 0.70

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 7.6e-07
                             EEES-TT-HHHHH--S-....EEEEESS......-SSTTE....EES-TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEE CS
          Methyltransf_8  77 adlGcGeakiaeavrek..ekvrsfdlv......avnerv....vacdlakvPledesvdvavfclslm.gtnladflkeanrvlkv 150
                              dlGcG + ia++ ++   e++   d++      ++++++    v+ d   +P ++++ d++v  lsl  +++l + l+e++rvlk+
  tr|G1K8X1|G1K8X1_ANOCA  78 LDLGCGRSYIAQHLNKDiiERLFQADVAenalkkPIESEIprisVVADEEFLPFKENTFDLVVSGLSLHwVNDLPKALHEVHRVLKP 164
                             6999999999966554311444444543221111233332222356788899****************64899************** PP

                             EEEE CS
          Methyltransf_8 151 GGll 154
                              G++
  tr|G1K8X1|G1K8X1_ANOCA 165 DGVF 168
                             9986 PP

>> tr|R4GB35|R4GB35_ANOCA  mRNA cap guanine-N7 methyltransferase OS=Anolis carolinensis OX=28377 GN=RNMT PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   3.9e-06     0.012      60     111 ..     224     275 ..     203     292 .. 0.78
   2 ?   -4.0   0.0       3.7   1.2e+04       7      32 ..     365     390 ..     363     394 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 3.9e-06
                             HHHHHHHHCTS-TTS-EEEES-TT-H..HHHH--S-..EEEEESS-SSTTEEES CS
          Methyltransf_8  60 ldviirklkkkkdnlvvadlGcGeak..iaeavrekekvrsfdlvavnervvac 111
                             + +++ k++++k+n++v dlGcG+    +  ++++  ++ + d++a+   v+ c
  tr|R4GB35|R4GB35_ANOCA 224 IGEFLDKVRRRKQNITVLDLGCGKGGdlLKWRKGRISRLVCTDIAAIS--VQQC 275
                             568999****************98642256899999999999999985..4445 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 3.7
                             -HHHHHHHHHHHHHHHHHS-HHHHHH CS
          Methyltransf_8   7 kkrldgarfrflneklytgesskavd 32 
                              krl++++   + +++yt + +k+ +
  tr|R4GB35|R4GB35_ANOCA 365 VKRLEASQTDSFGNEIYTVKFEKKGQ 390
                             68999999999999999988877765 PP

>> tr|R4G9E3|R4G9E3_ANOCA  Arsenite methyltransferase OS=Anolis carolinensis OX=28377 GN=AS3MT PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.1     0.058   1.8e+02      74     106 ..      69     105 ..      32     112 .. 0.77
   2 ?   11.9   0.0     5e-05      0.15      75     161 ..      94     185 ..      84     196 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.058
                             S-EEEES-TT-H....HHHH--S-..EEEEESS-SST CS
          Methyltransf_8  74 lvvadlGcGeak....iaeavrekekvrsfdlvavne 106
                               + dlGcG  +    +++ v+e+ ++  +d++  + 
  tr|R4G9E3|R4G9E3_ANOCA  69 CWILDLGCGSGRdcymLSQLVGENGHITGIDMTEAQV 105
                             5699*****8773222336677777777777766555 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 5e-05
                             -EEEES-TT-HHHHH--S.-..EEEEESS-SSTTEEES-TTS-S...--TT-EEEEE.EES---SS-HHHHHHHHHHHEEEEEEEEE CS
          Methyltransf_8  75 vvadlGcGeakiaeavre.kekvrsfdlvavnervvacdlakvP...ledesvdvav.fclslmgtnladflkeanrvlkvGGllkv 156
                              +  +   ea++  a+++   +++ f  + +n + + c + k+    l+ e  ++++  c+  ++ + +  l+ea+++lk GG ++ 
  tr|R4G9E3|R4G9E3_ANOCA  94 HITGIDMTEAQVEVAKKHiDYHMNKFGYKKPNVNFIHCYMEKLSeagLKGECYNLVIsNCVINLSPDKRAVLHEAYQMLKAGGEMYF 180
                             455555666666644433145789999999*********98775222788999988835999999*********************9 PP

                             EEEGG CS
          Methyltransf_8 157 aevks 161
                             ++v +
  tr|R4G9E3|R4G9E3_ANOCA 181 SDVYA 185
                             99865 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (219 nodes)
Target sequences:                        18528  (9796552 residues searched)
Passed MSV filter:                       445  (0.0240177); expected 370.6 (0.02)
Passed bias filter:                      300  (0.0161917); expected 370.6 (0.02)
Passed Vit filter:                        26  (0.00140328); expected 18.5 (0.001)
Passed Fwd filter:                         6  (0.000323834); expected 0.2 (1e-05)
Initial search space (Z):              18528  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.15u 0.01s 00:00:00.16 Elapsed: 00:00:00.07
# Mc/sec: 30649.21
//
[ok]