# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_8.hmm.txt
# target sequence database: proteomes/Drosophila_melanogaster.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_8 [M=219]
Accession: PF05148.15
Description: Hypothetical methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
8.4e-75 251.0 0.2 1.1e-74 250.7 0.2 1.1 1 sp|Q7K2B0|RRP8_DROME Ribosomal RNA-processing protein 8 OS
1.8e-05 24.4 0.0 3.1e-05 23.6 0.0 1.3 1 tr|Q9W232|Q9W232_DROME Uncharacterized protein OS=Drosophila
0.0001 21.9 0.0 0.0002 20.9 0.0 1.4 1 tr|Q9VBJ3|Q9VBJ3_DROME Fire dancer OS=Drosophila melanogaste
0.0018 17.8 0.0 0.26 10.7 0.0 2.3 2 sp|Q9VYF8|COQ5_DROME 2-methoxy-6-polyprenyl-1,4-benzoquino
0.0077 15.7 0.0 0.014 14.9 0.0 1.5 1 sp|Q86BS6|METL_DROME Methyltransferase-like protein OS=Dro
Domain annotation for each sequence (and alignments):
>> sp|Q7K2B0|RRP8_DROME Ribosomal RNA-processing protein 8 OS=Drosophila melanogaster OX=7227 GN=CG7137 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 250.7 0.2 3.8e-78 1.1e-74 2 219 .] 142 358 .] 141 358 .] 0.97
Alignments for each domain:
== domain 1 score: 250.7 bits; conditional E-value: 3.8e-78
XXXXX-HHHHHHHHHHHHHHHHHS-HHHHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH- CS
Methyltransf_8 2 leakikkrldgarfrflneklytgesskavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeav 90
l k++ l g+rfr++ne+ly+++s ka lf++d +af+ yh+g+r+qv+kWP nPl++ii+++kk ++ ++ d+GcGe k+a++v
sp|Q7K2B0|RRP8_DROME 142 LASKLQSELLGGRFRYINEQLYSTTSRKAEALFRKDSSAFEAYHAGYRQQVEKWPINPLNRIIKTIKKIPKTAIIGDFGCGEGKLAQSV 230
67899999******************************************************************************888 PP
-S-..EEEEESS-SSTTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S-HHHHHHHHHCTTEE CS
Methyltransf_8 91 rekekvrsfdlvavnervvacdlakvPledesvdvavfclslmgtnladflkeanrvlkvGGllkvaevksrfesvklfaraltklGfe 179
+k v s+dlva ++++ac+++ Pl+ + dvav+clslmgt+l++f eanrvlk G +++ae++srf++v+ f+r l+ Gf+
sp|Q7K2B0|RRP8_DROME 231 PNK--VYSMDLVAARSDIIACNITDTPLQARTLDVAVYCLSLMGTDLNEFFLEANRVLKLHGTVYIAEIQSRFQDVREFVRCLNACGFD 317
776..************************************************************************************ PP
EEEEE--STTEEEEEEEE-SSS-TT---.GG--------XX CS
Methyltransf_8 180 vkskdlsnkqfvlfefkkvekkgkkrel.glklkpclykkr 219
++kd+ ++f +f+fkk+ ++ k ++ lkpcly+kr
sp|Q7K2B0|RRP8_DROME 318 LNKKDVAVNYFYFFQFKKMRHVPKNTKMkAFSLKPCLYRKR 358
********************88887777589********98 PP
>> tr|Q9W232|Q9W232_DROME Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG17807 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 23.6 0.0 1.1e-08 3.1e-05 30 155 .. 354 489 .. 344 528 .. 0.73
Alignments for each domain:
== domain 1 score: 23.6 bits; conditional E-value: 1.1e-08
HHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..EEE...EESS-SS....TTEE CS
Methyltransf_8 30 avdlfkedpeafdlyhkgfrsqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeavrekekvrs...fdlvavn....ervv 109
a+ + e+ ++ ++y k ++ + + P ++ + l + + + vv d+GcG+ k + v + l av+ ++v
tr|Q9W232|Q9W232_DROME 354 AQAITLEQQNVHEVYDKI-ADHFSETRHTPWPQVSEFLDSFEPQSVVLDIGCGNGKYLSCNPLLLSVGCdraQGLLAVGrrkgQNVF 439
444445777777787765.445556667788888899999999*************99777777777542225677775222267** PP
ES-TTS-S--TT-EE..EEEEES---SS-HH..HHHHHHHHHEEEEEEEE CS
Methyltransf_8 110 acdlakvPledesvd..vavfclslmgtnla..dflkeanrvlkvGGllk 155
cd vP+ +s+d + + + ++t+ + l+e+ rvl++GG
tr|Q9W232|Q9W232_DROME 440 RCDCLVVPVRSSSIDgcISIAVIHHLATKERrlAALQEMARVLRPGGRAL 489
*************99765566666566554412679***********654 PP
>> tr|Q9VBJ3|Q9VBJ3_DROME Fire dancer OS=Drosophila melanogaster OX=7227 GN=fid PE=4 SV=3
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.9 0.0 7.4e-08 0.0002 63 157 .. 152 258 .. 131 276 .. 0.65
Alignments for each domain:
== domain 1 score: 20.9 bits; conditional E-value: 7.4e-08
HHHHHCTS-TTS-EEEES-TT-HHH....HH--S-..EEEEESS-SST....TEEES-TTS-S--TT-EEEEEEES---.....SS- CS
Methyltransf_8 63 iirklkkkkdnlvvadlGcGeakia....eavrekekvrsfdlvavne....rvvacdlakvPledesvdvavfclslm.....gtn 136
+++ l + vv d+GcG + a+ r++ l v + +v cd ++P d+s d v+ l+++ ++
tr|Q9VBJ3|Q9VBJ3_DROME 152 MAHFLSGLDPGSVVCDVGCGSGRYLtqcnPAICTIGVERCYRLSKVAHekggEVALCDNLELPFRDDSFDA-VLSLAVVhhfatTER 237
4444555566789********99762222233333334677776554312337*****************5.444554312211334 PP
HHHHHHHHHHHEEEEEEEEEE CS
Methyltransf_8 137 ladflkeanrvlkvGGllkva 157
+ l+e r+l++GG + ++
tr|Q9VBJ3|Q9VBJ3_DROME 238 RVQALRELARILRIGGRVVIT 258
45789***********87764 PP
>> sp|Q9VYF8|COQ5_DROME 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Drosophila melanogaster OX=7
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 10.7 0.0 9.4e-05 0.26 69 159 .. 130 221 .. 116 235 .. 0.76
2 ! 4.6 0.0 0.0073 20 155 185 .. 257 287 .. 251 295 .. 0.84
Alignments for each domain:
== domain 1 score: 10.7 bits; conditional E-value: 9.4e-05
TS-TTS-EEEES-TT-HHHHH--S-..EEEEESS-SSTTEEES-TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEE CS
Methyltransf_8 69 kkkdnlvvadlGcGeakiaeavrekekvrsfdlvavnervvacdlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkv 156
+++++++v d+ + e+ + + + l + d k+P d s + + + t + + l ea+rvl++GG ++
sp|Q9VYF8|COQ5_DROME 130 QRPSHVTVSDINQHMLNVGEERAKRLGLTTDQLSNCTVAWQCADAEKLPFPDASFTAYTIAFGIRnCTHVDKVLSEAYRVLQPGGRFMC 218
56666666666666666666666666666666666666667779999*****99988777777752689999*************9988 PP
EEE CS
Methyltransf_8 157 aev 159
e
sp|Q9VYF8|COQ5_DROME 219 LEF 221
776 PP
== domain 2 score: 4.6 bits; conditional E-value: 0.0073
EEEEEGGG-S-HHHHHHHHHCTTEEEEEEE- CS
Methyltransf_8 155 kvaevksrfesvklfaraltklGfevkskdl 185
++ e rf++ ++f++ +++ Gf+++s +
sp|Q9VYF8|COQ5_DROME 257 YLVESIRRFPKQEQFKQMIEQAGFDQVSYEN 287
5566678******************998765 PP
>> sp|Q86BS6|METL_DROME Methyltransferase-like protein OS=Drosophila melanogaster OX=7227 GN=metl PE=1 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.9 0.0 5e-06 0.014 99 155 .. 180 241 .. 132 266 .. 0.76
Alignments for each domain:
== domain 1 score: 14.9 bits; conditional E-value: 5e-06
EESS-SSTTEE..ES-TTS-S--TT-EEEEE..EES---S.S-HHHHHHHHHHHEEEEEEEE CS
Methyltransf_8 99 fdlvavnervv..acdlakvPledesvdvav..fclslmg.tnladflkeanrvlkvGGllk 155
fd + + v+ + d +vP e++s d++v f ls + ++++ l + +r l++GGll
sp|Q86BS6|METL_DROME 180 FDEKRCEVFVMdaTLDHWQVPFEENSQDIIVmiFVLSAIEpKKMQRVLDNCYRYLRPGGLLL 241
5555555555411346689*********986226677554378999*************996 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (219 nodes)
Target sequences: 13786 (7394964 residues searched)
Passed MSV filter: 342 (0.0248078); expected 275.7 (0.02)
Passed bias filter: 250 (0.0181343); expected 275.7 (0.02)
Passed Vit filter: 23 (0.00166836); expected 13.8 (0.001)
Passed Fwd filter: 5 (0.000362687); expected 0.1 (1e-05)
Initial search space (Z): 13786 [actual number of targets]
Domain search space (domZ): 5 [number of targets reported over threshold]
# CPU time: 0.13u 0.01s 00:00:00.14 Elapsed: 00:00:00.05
# Mc/sec: 32389.94
//
[ok]