# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_8.hmm.txt
# target sequence database: proteomes/Macaca_mulatta.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_8 [M=219]
Accession: PF05148.15
Description: Hypothetical methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
5.5e-106 353.6 0.0 7e-106 353.2 0.0 1.1 1 tr|F7C3H4|F7C3H4_MACMU Ribosomal RNA processing 8 OS=Ma
2.5e-06 27.8 0.0 3.9e-06 27.1 0.0 1.2 1 tr|A0A1D5Q0I7|A0A1D5Q0I7_MACMU tRNA methyltransferase 9B (putat
6.4e-06 26.4 0.0 1.1e-05 25.7 0.0 1.3 1 tr|F6X1K2|F6X1K2_MACMU Methyltransferase like 7A OS=Mac
7.9e-05 22.8 0.0 0.00015 21.9 0.0 1.4 1 tr|F6X6T3|F6X6T3_MACMU Methyltransferase like 7B OS=Mac
9e-05 22.7 0.0 0.00015 21.9 0.0 1.3 1 tr|A0A1D5QHE1|A0A1D5QHE1_MACMU AlkB homolog 8, tRNA methyltrans
9.4e-05 22.6 0.0 0.00021 21.5 0.0 1.6 1 tr|A0A1D5R6R2|A0A1D5R6R2_MACMU Arsenite methyltransferase OS=Ma
0.00017 21.8 0.0 0.0063 16.6 0.0 2.7 3 tr|A0A1D5QG92|A0A1D5QG92_MACMU 2-methoxy-6-polyprenyl-1,4-benzo
------ inclusion threshold ------
0.016 15.3 0.4 0.064 13.3 0.0 2.1 2 tr|F7H715|F7H715_MACMU THUMP domain containing 2 OS=Mac
Domain annotation for each sequence (and alignments):
>> tr|F7C3H4|F7C3H4_MACMU Ribosomal RNA processing 8 OS=Macaca mulatta OX=9544 GN=RRP8 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 353.2 0.0 2.6e-109 7e-106 1 219 [] 237 456 .] 237 456 .] 0.99
Alignments for each domain:
== domain 1 score: 353.2 bits; conditional E-value: 2.6e-109
XXXXXX-HHHHHHHHHHHHHHHHHS-HHHHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHH CS
Methyltransf_8 1 dleakikkrldgarfrflneklytgesskavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklkkkkdnlvvadlGcGeakia 87
dl+a++++rldgarfr+lne+ly+g+ss+a++lf+edpeaf +yh+gf+sqvkkWP +P+d i+r+l++++++lvvad+GcG++++a
tr|F7C3H4|F7C3H4_MACMU 237 DLRARMAQRLDGARFRYLNEQLYSGPSSAAQRLFQEDPEAFLVYHRGFQSQVKKWPLQPVDGIARDLRQRPASLVVADFGCGDCRLA 323
689************************************************************************************ PP
HH--S-..EEEEESS-SSTTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S-HHHHHHHHH CS
Methyltransf_8 88 eavrekekvrsfdlvavnervvacdlakvPledesvdvavfclslmgtnladflkeanrvlkvGGllkvaevksrfesvklfaralt 174
+++r++ v++fdl+++++rv++cd+a+vPledesvdvavfclslmgtn++dfl+eanrvlk+GGllkvaev+srfe+v++f+ra+t
tr|F7C3H4|F7C3H4_MACMU 324 SSIRNP--VHCFDLASLDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKPGGLLKVAEVSSRFEDVRTFLRAVT 408
*****9..******************************************************************************* PP
CTTEEEEEEE--STTEEEEEEEE-S..SS-TT---.GG--------XX CS
Methyltransf_8 175 klGfevkskdlsnkqfvlfefkkve..kkgkkrel.glklkpclykkr 219
klGf+++skdl+n++f+lf+f+k++ ++g+k++l glkl+pclyk+r
tr|F7C3H4|F7C3H4_MACMU 409 KLGFKIVSKDLTNSHFFLFDFQKTGppQVGPKAQLsGLKLHPCLYKRR 456
************************8889*****9999**********9 PP
>> tr|A0A1D5Q0I7|A0A1D5Q0I7_MACMU tRNA methyltransferase 9B (putative) OS=Macaca mulatta OX=9544 GN=TRMT9B PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 27.1 0.0 1.5e-09 3.9e-06 50 156 .. 27 139 .. 3 170 .. 0.72
Alignments for each domain:
== domain 1 score: 27.1 bits; conditional E-value: 1.5e-09
HHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..EEE...EESS-SST....TEEES-TTS-S--TT CS
Methyltransf_8 50 sqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeavrekekvrs...fdlvavne....rvvacdlakvPlede 121
q k WP + + l+++k ++ad+GcG k + ++ + v + lv + + ++cd ++P de
tr|A0A1D5Q0I7|A0A1D5Q0I7_MACMU 27 LQSKAWPR-----VRQFLQEQKPGSIIADIGCGTGKYLKVNSQVHTVGCdycGPLVEIARdrgcEAMVCDNLNLPFRDE 100
46777774.....4566777888899***********9888999988762223465554311225789*********** PP
-EEEEEEE..S---SS-HH..HHHHHHHHHEEEEEEEEE CS
Methyltransf_8 122 svdvavfc..lslmgtnla..dflkeanrvlkvGGllkv 156
d ++ + +t+ + +ke+ rvl +GG l++
tr|A0A1D5Q0I7|A0A1D5Q0I7_MACMU 101 GFDAVISIgvIHHFSTKQRriRAIKEMARVLVPGGQLMI 139
**9766531144455554412479***********9987 PP
>> tr|F6X1K2|F6X1K2_MACMU Methyltransferase like 7A OS=Macaca mulatta OX=9544 GN=METTL7A PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 25.7 0.0 4e-09 1.1e-05 118 158 .. 133 174 .. 118 200 .. 0.83
Alignments for each domain:
== domain 1 score: 25.7 bits; conditional E-value: 4e-09
--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEE CS
Methyltransf_8 118 ledesvdvavfclslm.gtnladflkeanrvlkvGGllkvae 158
++d+svdv+v+ l l ++n ++ l+e+ rvl++GG ++ e
tr|F6X1K2|F6X1K2_MACMU 133 VADGSVDVVVCTLVLCsVKNQEQILREVCRVLRPGGAFYFME 174
68************973689999*************999776 PP
>> tr|F6X6T3|F6X6T3_MACMU Methyltransferase like 7B OS=Macaca mulatta OX=9544 GN=METTL7B PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.9 0.0 5.6e-08 0.00015 112 157 .. 129 173 .. 119 187 .. 0.85
Alignments for each domain:
== domain 1 score: 21.9 bits; conditional E-value: 5.6e-08
-TTS-S--TT-EEEEEEES---S.S-HHHHHHHHHHHEEEEEEEEEE CS
Methyltransf_8 112 dlakvPledesvdvavfclslmg.tnladflkeanrvlkvGGllkva 157
d+++ l+d+s+dv+v+ l l + + ++ l+e++rvl++GG+l+
tr|F6X6T3|F6X6T3_MACMU 129 DMRQ--LADGSMDVVVCTLVLCSvQSPRKVLQEVQRVLRPGGVLFFW 173
5555..68************9861567999*************9865 PP
>> tr|A0A1D5QHE1|A0A1D5QHE1_MACMU AlkB homolog 8, tRNA methyltransferase OS=Macaca mulatta OX=9544 GN=ALKBH8 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.9 0.0 5.7e-08 0.00015 57 155 .. 327 436 .. 299 455 .. 0.74
Alignments for each domain:
== domain 1 score: 21.9 bits; conditional E-value: 5.7e-08
S-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..E...EEEESS-S....STTEEES-TTS-S--TT-EE.... CS
Methyltransf_8 57 enPldviirklkkkkdnlvvadlGcGeakiaeavrekekv...rsfdlvav....nervvacdlakvPledesvd.... 124
+ P +i++ lk ++ +vad+GcG+ k +e v rs +lv + + + +cd vP+ +s d
tr|A0A1D5QHE1|A0A1D5QHE1_MACMU 327 HTPWPHIVEFLKALPSGSIVADIGCGNGKYLGVNKELYMVgcdRSQNLVDIcrerQFQAFVCDALAVPVCSGSCDacis 405
568889***********************99777777666333456666552111335789********9888883322 PP
EEEEES---SS-HHHHHHHHHHHEEEEEEEE CS
Methyltransf_8 125 vavfclslmgtnladflkeanrvlkvGGllk 155
+av+ ++ l+e+ r+l++GG
tr|A0A1D5QHE1|A0A1D5QHE1_MACMU 406 IAVIHHFATAERRVAALQEIVRLLRPGGKAL 436
34444444455566789***********754 PP
>> tr|A0A1D5R6R2|A0A1D5R6R2_MACMU Arsenite methyltransferase OS=Macaca mulatta OX=9544 GN=AS3MT PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.5 0.0 7.8e-08 0.00021 78 163 .. 102 190 .. 85 201 .. 0.72
Alignments for each domain:
== domain 1 score: 21.5 bits; conditional E-value: 7.8e-08
EES-TT-HHHHH--S-..EEEEESS-SSTTEEES-TTS-...S--TT-EEEEEE.ES---SS-HHHHHHHHHHHEEEEE CS
Methyltransf_8 78 dlGcGeakiaeavrekekvrsfdlvavnervvacdlakv...Pledesvdvavf.clslmgtnladflkeanrvlkvGG 152
d+ G++ +ae+ + +++ + ++a n + + k+ +++es d++v c+ ++ + ++ l+ea+rvlk GG
tr|A0A1D5R6R2|A0A1D5R6R2_MACMU 102 DMTKGQVEVAEKYLDY-HMEKYGFQASNVTFIHGYIEKLgeaGIKNESYDIVVSnCVINLVPDKQQVLQEAYRVLKHGG 179
5555666666444444.45556666666666666555542215789*****995499999******************* PP
EEEEEEEGGG- CS
Methyltransf_8 153 llkvaevksrf 163
l+ ++v + +
tr|A0A1D5R6R2|A0A1D5R6R2_MACMU 180 ELYFSDVYTSL 190
****9997665 PP
>> tr|A0A1D5QG92|A0A1D5QG92_MACMU 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Macaca mulatta OX=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.5 0.0 3.4 9.1e+03 106 115 .. 165 174 .. 163 178 .. 0.81
2 ! 16.6 0.0 2.4e-06 0.0063 112 158 .. 199 246 .. 192 265 .. 0.87
3 ? 1.9 0.0 0.076 2e+02 156 187 .. 284 315 .. 278 322 .. 0.81
Alignments for each domain:
== domain 1 score: -3.5 bits; conditional E-value: 3.4
TTEEES-TTS CS
Methyltransf_8 106 ervvacdlak 115
+rvv+cd++k
tr|A0A1D5QG92|A0A1D5QG92_MACMU 165 SRVVVCDINK 174
689****976 PP
== domain 2 score: 16.6 bits; conditional E-value: 2.4e-06
-TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEE CS
Methyltransf_8 112 dlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkvae 158
d ++P +d+ d+ + + + +t + + l+ea+rvlk+GG + e
tr|A0A1D5QG92|A0A1D5QG92_MACMU 199 DAEELPFDDDKFDIYTIAFGIRnVTHIDQALQEAHRVLKPGGRFLCLE 246
7889**********99999985389*****************987666 PP
== domain 3 score: 1.9 bits; conditional E-value: 0.076
EEEEGGG-S-HHHHHHHHHCTTEEEEEEE--S CS
Methyltransf_8 156 vaevksrfesvklfaraltklGfevkskdlsn 187
+ e rf+s + f++ ++ Gf+ + + +
tr|A0A1D5QG92|A0A1D5QG92_MACMU 284 LVESIRRFPSQEEFKEMIEDAGFHKVTYESLT 315
566677*****************988776655 PP
>> tr|F7H715|F7H715_MACMU THUMP domain containing 2 OS=Macaca mulatta OX=9544 GN=THUMPD2 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -0.9 0.1 0.54 1.4e+03 6 48 .. 34 78 .. 30 157 .. 0.59
2 ? 13.3 0.0 2.4e-05 0.064 113 155 .. 358 405 .. 341 421 .. 0.81
Alignments for each domain:
== domain 1 score: -0.9 bits; conditional E-value: 0.54
X-HHHHHHHHHHHHHHHHHS-HHHHHHH..HHH-HHHHHHHHHHH CS
Methyltransf_8 6 ikkrldgarfrflneklytgesskavdl..fkedpeafdlyhkgf 48
++ rl +++ ++ k++ ++ s l +k +f l k f
tr|F7H715|F7H715_MACMU 34 VRARLAATEVEYISGKVFFTTCSDLNMLkkLKSAERLFLLIKKQF 78
556666666666666666555444332211334444444444444 PP
== domain 2 score: 13.3 bits; conditional E-value: 2.4e-05
TTS-S--TT-EEEEEEES--.....-SS-HHHHHHHHHHHEEEEEEEE CS
Methyltransf_8 113 lakvPledesvdvavfclsl.....mgtnladflkeanrvlkvGGllk 155
+ ++Pl esvd+++ + + +g+++++ l+e++rvl+vGG +
tr|F7H715|F7H715_MACMU 358 VIELPLPSESVDIIISDIPFgkkfkLGKDIKSILQEMERVLHVGGTIV 405
5689***********887654444589******************864 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (219 nodes)
Target sequences: 21211 (10888574 residues searched)
Passed MSV filter: 478 (0.0225355); expected 424.2 (0.02)
Passed bias filter: 349 (0.0164537); expected 424.2 (0.02)
Passed Vit filter: 25 (0.00117863); expected 21.2 (0.001)
Passed Fwd filter: 8 (0.000377163); expected 0.2 (1e-05)
Initial search space (Z): 21211 [actual number of targets]
Domain search space (domZ): 8 [number of targets reported over threshold]
# CPU time: 0.16u 0.01s 00:00:00.17 Elapsed: 00:00:00.07
# Mc/sec: 34065.68
//
[ok]