# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_8.hmm.txt # target sequence database: proteomes/Macaca_mulatta.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_8 [M=219] Accession: PF05148.15 Description: Hypothetical methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.5e-106 353.6 0.0 7e-106 353.2 0.0 1.1 1 tr|F7C3H4|F7C3H4_MACMU Ribosomal RNA processing 8 OS=Ma 2.5e-06 27.8 0.0 3.9e-06 27.1 0.0 1.2 1 tr|A0A1D5Q0I7|A0A1D5Q0I7_MACMU tRNA methyltransferase 9B (putat 6.4e-06 26.4 0.0 1.1e-05 25.7 0.0 1.3 1 tr|F6X1K2|F6X1K2_MACMU Methyltransferase like 7A OS=Mac 7.9e-05 22.8 0.0 0.00015 21.9 0.0 1.4 1 tr|F6X6T3|F6X6T3_MACMU Methyltransferase like 7B OS=Mac 9e-05 22.7 0.0 0.00015 21.9 0.0 1.3 1 tr|A0A1D5QHE1|A0A1D5QHE1_MACMU AlkB homolog 8, tRNA methyltrans 9.4e-05 22.6 0.0 0.00021 21.5 0.0 1.6 1 tr|A0A1D5R6R2|A0A1D5R6R2_MACMU Arsenite methyltransferase OS=Ma 0.00017 21.8 0.0 0.0063 16.6 0.0 2.7 3 tr|A0A1D5QG92|A0A1D5QG92_MACMU 2-methoxy-6-polyprenyl-1,4-benzo ------ inclusion threshold ------ 0.016 15.3 0.4 0.064 13.3 0.0 2.1 2 tr|F7H715|F7H715_MACMU THUMP domain containing 2 OS=Mac Domain annotation for each sequence (and alignments): >> tr|F7C3H4|F7C3H4_MACMU Ribosomal RNA processing 8 OS=Macaca mulatta OX=9544 GN=RRP8 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 353.2 0.0 2.6e-109 7e-106 1 219 [] 237 456 .] 237 456 .] 0.99 Alignments for each domain: == domain 1 score: 353.2 bits; conditional E-value: 2.6e-109 XXXXXX-HHHHHHHHHHHHHHHHHS-HHHHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHH CS Methyltransf_8 1 dleakikkrldgarfrflneklytgesskavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklkkkkdnlvvadlGcGeakia 87 dl+a++++rldgarfr+lne+ly+g+ss+a++lf+edpeaf +yh+gf+sqvkkWP +P+d i+r+l++++++lvvad+GcG++++a tr|F7C3H4|F7C3H4_MACMU 237 DLRARMAQRLDGARFRYLNEQLYSGPSSAAQRLFQEDPEAFLVYHRGFQSQVKKWPLQPVDGIARDLRQRPASLVVADFGCGDCRLA 323 689************************************************************************************ PP HH--S-..EEEEESS-SSTTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S-HHHHHHHHH CS Methyltransf_8 88 eavrekekvrsfdlvavnervvacdlakvPledesvdvavfclslmgtnladflkeanrvlkvGGllkvaevksrfesvklfaralt 174 +++r++ v++fdl+++++rv++cd+a+vPledesvdvavfclslmgtn++dfl+eanrvlk+GGllkvaev+srfe+v++f+ra+t tr|F7C3H4|F7C3H4_MACMU 324 SSIRNP--VHCFDLASLDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKPGGLLKVAEVSSRFEDVRTFLRAVT 408 *****9..******************************************************************************* PP CTTEEEEEEE--STTEEEEEEEE-S..SS-TT---.GG--------XX CS Methyltransf_8 175 klGfevkskdlsnkqfvlfefkkve..kkgkkrel.glklkpclykkr 219 klGf+++skdl+n++f+lf+f+k++ ++g+k++l glkl+pclyk+r tr|F7C3H4|F7C3H4_MACMU 409 KLGFKIVSKDLTNSHFFLFDFQKTGppQVGPKAQLsGLKLHPCLYKRR 456 ************************8889*****9999**********9 PP >> tr|A0A1D5Q0I7|A0A1D5Q0I7_MACMU tRNA methyltransferase 9B (putative) OS=Macaca mulatta OX=9544 GN=TRMT9B PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.1 0.0 1.5e-09 3.9e-06 50 156 .. 27 139 .. 3 170 .. 0.72 Alignments for each domain: == domain 1 score: 27.1 bits; conditional E-value: 1.5e-09 HHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..EEE...EESS-SST....TEEES-TTS-S--TT CS Methyltransf_8 50 sqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeavrekekvrs...fdlvavne....rvvacdlakvPlede 121 q k WP + + l+++k ++ad+GcG k + ++ + v + lv + + ++cd ++P de tr|A0A1D5Q0I7|A0A1D5Q0I7_MACMU 27 LQSKAWPR-----VRQFLQEQKPGSIIADIGCGTGKYLKVNSQVHTVGCdycGPLVEIARdrgcEAMVCDNLNLPFRDE 100 46777774.....4566777888899***********9888999988762223465554311225789*********** PP -EEEEEEE..S---SS-HH..HHHHHHHHHEEEEEEEEE CS Methyltransf_8 122 svdvavfc..lslmgtnla..dflkeanrvlkvGGllkv 156 d ++ + +t+ + +ke+ rvl +GG l++ tr|A0A1D5Q0I7|A0A1D5Q0I7_MACMU 101 GFDAVISIgvIHHFSTKQRriRAIKEMARVLVPGGQLMI 139 **9766531144455554412479***********9987 PP >> tr|F6X1K2|F6X1K2_MACMU Methyltransferase like 7A OS=Macaca mulatta OX=9544 GN=METTL7A PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.0 4e-09 1.1e-05 118 158 .. 133 174 .. 118 200 .. 0.83 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 4e-09 --TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEE CS Methyltransf_8 118 ledesvdvavfclslm.gtnladflkeanrvlkvGGllkvae 158 ++d+svdv+v+ l l ++n ++ l+e+ rvl++GG ++ e tr|F6X1K2|F6X1K2_MACMU 133 VADGSVDVVVCTLVLCsVKNQEQILREVCRVLRPGGAFYFME 174 68************973689999*************999776 PP >> tr|F6X6T3|F6X6T3_MACMU Methyltransferase like 7B OS=Macaca mulatta OX=9544 GN=METTL7B PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.0 5.6e-08 0.00015 112 157 .. 129 173 .. 119 187 .. 0.85 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 5.6e-08 -TTS-S--TT-EEEEEEES---S.S-HHHHHHHHHHHEEEEEEEEEE CS Methyltransf_8 112 dlakvPledesvdvavfclslmg.tnladflkeanrvlkvGGllkva 157 d+++ l+d+s+dv+v+ l l + + ++ l+e++rvl++GG+l+ tr|F6X6T3|F6X6T3_MACMU 129 DMRQ--LADGSMDVVVCTLVLCSvQSPRKVLQEVQRVLRPGGVLFFW 173 5555..68************9861567999*************9865 PP >> tr|A0A1D5QHE1|A0A1D5QHE1_MACMU AlkB homolog 8, tRNA methyltransferase OS=Macaca mulatta OX=9544 GN=ALKBH8 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.0 5.7e-08 0.00015 57 155 .. 327 436 .. 299 455 .. 0.74 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 5.7e-08 S-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..E...EEEESS-S....STTEEES-TTS-S--TT-EE.... CS Methyltransf_8 57 enPldviirklkkkkdnlvvadlGcGeakiaeavrekekv...rsfdlvav....nervvacdlakvPledesvd.... 124 + P +i++ lk ++ +vad+GcG+ k +e v rs +lv + + + +cd vP+ +s d tr|A0A1D5QHE1|A0A1D5QHE1_MACMU 327 HTPWPHIVEFLKALPSGSIVADIGCGNGKYLGVNKELYMVgcdRSQNLVDIcrerQFQAFVCDALAVPVCSGSCDacis 405 568889***********************99777777666333456666552111335789********9888883322 PP EEEEES---SS-HHHHHHHHHHHEEEEEEEE CS Methyltransf_8 125 vavfclslmgtnladflkeanrvlkvGGllk 155 +av+ ++ l+e+ r+l++GG tr|A0A1D5QHE1|A0A1D5QHE1_MACMU 406 IAVIHHFATAERRVAALQEIVRLLRPGGKAL 436 34444444455566789***********754 PP >> tr|A0A1D5R6R2|A0A1D5R6R2_MACMU Arsenite methyltransferase OS=Macaca mulatta OX=9544 GN=AS3MT PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.0 7.8e-08 0.00021 78 163 .. 102 190 .. 85 201 .. 0.72 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 7.8e-08 EES-TT-HHHHH--S-..EEEEESS-SSTTEEES-TTS-...S--TT-EEEEEE.ES---SS-HHHHHHHHHHHEEEEE CS Methyltransf_8 78 dlGcGeakiaeavrekekvrsfdlvavnervvacdlakv...Pledesvdvavf.clslmgtnladflkeanrvlkvGG 152 d+ G++ +ae+ + +++ + ++a n + + k+ +++es d++v c+ ++ + ++ l+ea+rvlk GG tr|A0A1D5R6R2|A0A1D5R6R2_MACMU 102 DMTKGQVEVAEKYLDY-HMEKYGFQASNVTFIHGYIEKLgeaGIKNESYDIVVSnCVINLVPDKQQVLQEAYRVLKHGG 179 5555666666444444.45556666666666666555542215789*****995499999******************* PP EEEEEEEGGG- CS Methyltransf_8 153 llkvaevksrf 163 l+ ++v + + tr|A0A1D5R6R2|A0A1D5R6R2_MACMU 180 ELYFSDVYTSL 190 ****9997665 PP >> tr|A0A1D5QG92|A0A1D5QG92_MACMU 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Macaca mulatta OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.5 0.0 3.4 9.1e+03 106 115 .. 165 174 .. 163 178 .. 0.81 2 ! 16.6 0.0 2.4e-06 0.0063 112 158 .. 199 246 .. 192 265 .. 0.87 3 ? 1.9 0.0 0.076 2e+02 156 187 .. 284 315 .. 278 322 .. 0.81 Alignments for each domain: == domain 1 score: -3.5 bits; conditional E-value: 3.4 TTEEES-TTS CS Methyltransf_8 106 ervvacdlak 115 +rvv+cd++k tr|A0A1D5QG92|A0A1D5QG92_MACMU 165 SRVVVCDINK 174 689****976 PP == domain 2 score: 16.6 bits; conditional E-value: 2.4e-06 -TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEE CS Methyltransf_8 112 dlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkvae 158 d ++P +d+ d+ + + + +t + + l+ea+rvlk+GG + e tr|A0A1D5QG92|A0A1D5QG92_MACMU 199 DAEELPFDDDKFDIYTIAFGIRnVTHIDQALQEAHRVLKPGGRFLCLE 246 7889**********99999985389*****************987666 PP == domain 3 score: 1.9 bits; conditional E-value: 0.076 EEEEGGG-S-HHHHHHHHHCTTEEEEEEE--S CS Methyltransf_8 156 vaevksrfesvklfaraltklGfevkskdlsn 187 + e rf+s + f++ ++ Gf+ + + + tr|A0A1D5QG92|A0A1D5QG92_MACMU 284 LVESIRRFPSQEEFKEMIEDAGFHKVTYESLT 315 566677*****************988776655 PP >> tr|F7H715|F7H715_MACMU THUMP domain containing 2 OS=Macaca mulatta OX=9544 GN=THUMPD2 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.1 0.54 1.4e+03 6 48 .. 34 78 .. 30 157 .. 0.59 2 ? 13.3 0.0 2.4e-05 0.064 113 155 .. 358 405 .. 341 421 .. 0.81 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 0.54 X-HHHHHHHHHHHHHHHHHS-HHHHHHH..HHH-HHHHHHHHHHH CS Methyltransf_8 6 ikkrldgarfrflneklytgesskavdl..fkedpeafdlyhkgf 48 ++ rl +++ ++ k++ ++ s l +k +f l k f tr|F7H715|F7H715_MACMU 34 VRARLAATEVEYISGKVFFTTCSDLNMLkkLKSAERLFLLIKKQF 78 556666666666666666555444332211334444444444444 PP == domain 2 score: 13.3 bits; conditional E-value: 2.4e-05 TTS-S--TT-EEEEEEES--.....-SS-HHHHHHHHHHHEEEEEEEE CS Methyltransf_8 113 lakvPledesvdvavfclsl.....mgtnladflkeanrvlkvGGllk 155 + ++Pl esvd+++ + + +g+++++ l+e++rvl+vGG + tr|F7H715|F7H715_MACMU 358 VIELPLPSESVDIIISDIPFgkkfkLGKDIKSILQEMERVLHVGGTIV 405 5689***********887654444589******************864 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (219 nodes) Target sequences: 21211 (10888574 residues searched) Passed MSV filter: 478 (0.0225355); expected 424.2 (0.02) Passed bias filter: 349 (0.0164537); expected 424.2 (0.02) Passed Vit filter: 25 (0.00117863); expected 21.2 (0.001) Passed Fwd filter: 8 (0.000377163); expected 0.2 (1e-05) Initial search space (Z): 21211 [actual number of targets] Domain search space (domZ): 8 [number of targets reported over threshold] # CPU time: 0.16u 0.01s 00:00:00.17 Elapsed: 00:00:00.07 # Mc/sec: 34065.68 // [ok]