# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_8.hmm.txt # target sequence database: proteomes/Monodelphis_domestica.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_8 [M=219] Accession: PF05148.15 Description: Hypothetical methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.3e-05 24.6 0.1 0.00012 22.2 0.1 1.9 1 tr|H9H5X9|H9H5X9_MONDO Methyltransferase like 7B OS=Monodelp 5.4e-05 23.4 0.0 9.5e-05 22.6 0.0 1.3 1 tr|F6ZD81|F6ZD81_MONDO AlkB homolog 8, tRNA methyltransferas 0.00026 21.2 0.0 0.0027 17.8 0.0 2.5 2 tr|F6WVA7|F6WVA7_MONDO 2-methoxy-6-polyprenyl-1,4-benzoquino 0.0023 18.1 0.0 0.005 17.0 0.0 1.5 1 tr|F7A935|F7A935_MONDO Uncharacterized protein OS=Monodelphi ------ inclusion threshold ------ 0.07 13.2 0.0 0.11 12.5 0.0 1.3 1 tr|F7FNN5|F7FNN5_MONDO Uncharacterized protein OS=Monodelphi 0.25 11.4 0.3 0.76 9.8 0.3 1.7 1 tr|F7F1Z8|F7F1Z8_MONDO Ubiquinone biosynthesis O-methyltrans Domain annotation for each sequence (and alignments): >> tr|H9H5X9|H9H5X9_MONDO Methyltransferase like 7B OS=Monodelphis domestica OX=13616 GN=METTL7B PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.2 0.1 3.5e-08 0.00012 112 156 .. 129 172 .. 47 178 .. 0.88 Alignments for each domain: == domain 1 score: 22.2 bits; conditional E-value: 3.5e-08 -TTS-S--TT-EEEEEEES---SS-.HHHHHHHHHHHEEEEEEEEE CS Methyltransf_8 112 dlakvPledesvdvavfclslmgtn.ladflkeanrvlkvGGllkv 156 d+++v +d+s+dv+v+ l l + + + l+e++rvlk+GG+++ tr|H9H5X9|H9H5X9_MONDO 129 DMSQV--ADGSMDVVVCTLVLCSVQsPSKVLQEVQRVLKPGGIFFF 172 66665..8*************8655167899***********9875 PP >> tr|F6ZD81|F6ZD81_MONDO AlkB homolog 8, tRNA methyltransferase OS=Monodelphis domestica OX=13616 GN=ALKBH8 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.6 0.0 2.7e-08 9.5e-05 56 155 .. 399 509 .. 363 529 .. 0.71 Alignments for each domain: == domain 1 score: 22.6 bits; conditional E-value: 2.7e-08 SS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..E...EEEESS-S....STTEEES-TTS-S--TT-EE....EEEEES- CS Methyltransf_8 56 PenPldviirklkkkkdnlvvadlGcGeakiaeavrekekv...rsfdlvav....nervvacdlakvPledesvd....vavfcls 131 + P +i+ lk ++ vvad+GcG+ k ++ v rs +lv + + + +cd vP+ e+ d +av+ tr|F6ZD81|F6ZD81_MONDO 399 RHTPWPQIVAFLKALPKGSVVADIGCGNGKYLGLSKDIYMVgcdRSQNLVEIcgerQFEAFVCDALAVPIRSETCDacisIAVIHHF 485 4578899***********************87555555555333677888753211234679*********9999844223333333 PP --SS-HHHHHHHHHHHEEEEEEEE CS Methyltransf_8 132 lmgtnladflkeanrvlkvGGllk 155 ++ l+e r+l++GG tr|F6ZD81|F6ZD81_MONDO 486 ATAERRLATLQELARLLRPGGKAL 509 3445556789***********754 PP >> tr|F6WVA7|F6WVA7_MONDO 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Monodelphis domestica OX=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 7.6e-07 0.0027 109 158 .. 187 237 .. 155 250 .. 0.88 2 ? -0.8 0.0 0.39 1.4e+03 156 184 .. 275 303 .. 269 309 .. 0.79 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 7.6e-07 EES-TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEE CS Methyltransf_8 109 vacdlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkvae 158 v+ d ++P +d+ d+ + + + +t + l+ea+rvlk+GG + e tr|F6WVA7|F6WVA7_MONDO 187 VVGDAEELPFDDDKFDIYTIAFGIRnVTHIDRALQEAYRVLKPGGRFLCLE 237 567999***********999999853899****************987666 PP == domain 2 score: -0.8 bits; conditional E-value: 0.39 EEEEGGG-S-HHHHHHHHHCTTEEEEEEE CS Methyltransf_8 156 vaevksrfesvklfaraltklGfevkskd 184 + e rf+ + f++ ++ Gf+ + + tr|F6WVA7|F6WVA7_MONDO 275 LVESIRRFPPQEEFKEMIEDAGFQKVTYE 303 55666799999************987665 PP >> tr|F7A935|F7A935_MONDO Uncharacterized protein OS=Monodelphis domestica OX=13616 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 1.4e-06 0.005 114 156 .. 19 61 .. 14 96 .. 0.81 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 1.4e-06 TS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEEEEEE CS Methyltransf_8 114 akvPledesvdvavfclslmgtnladflkeanrvlkvGGllkv 156 k+Pled+svdv +++ + fl e++rvlk+ G + tr|F7A935|F7A935_MONDO 19 EKLPLEDDSVDVLTAFVAIHWFDKVPFLMEVERVLKPHGCVAF 61 689**********************************998755 PP >> tr|F7FNN5|F7FNN5_MONDO Uncharacterized protein OS=Monodelphis domestica OX=13616 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 3.2e-05 0.11 102 156 .. 48 106 .. 15 121 .. 0.72 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 3.2e-05 S-SSTTEEES-TTS-S--TT-EEEEEEES--..-SS..-HHHHHHHHHHHEEEEEEEEE CS Methyltransf_8 102 vavnervvacdlakvPledesvdvavfclsl..mgt..nladflkeanrvlkvGGllkv 156 ++ + +v +cd ++P d+s d ++ + +t + ++e+ rvl +GG +++ tr|F7FNN5|F7FNN5_MONDO 48 HSRGCEVLVCDNLRLPFRDHSFDAVISIGVIhhFSTiqRRTRAVQEMARVLAPGGRVMI 106 456779*****************7765432211222113345789**********8776 PP >> tr|F7F1Z8|F7F1Z8_MONDO Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Monodelphis domestica OX=13616 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.8 0.3 0.00021 0.76 89 160 .. 177 251 .. 115 268 .. 0.80 Alignments for each domain: == domain 1 score: 9.8 bits; conditional E-value: 0.00021 H--S-..EEEEESS-SSTTE..EES-TTS-S--.TT-EEEEEEES--.-SS-HHHHHHHHHHHEEEEEEEEEEEEG CS Methyltransf_8 89 avrekekvrsfdlvavnerv..vacdlakvPle.desvdvavfclsl.mgtnladflkeanrvlkvGGllkvaevk 160 +++ ++ +sfd +++r+ ac l + e es d +v + +++l++f++ +vlk+GG l+++ ++ tr|F7F1Z8|F7F1Z8_MONDO 177 NIKTAQQHKSFDPI-LDKRIqyKACILEDIVEEtAESFDAVVASEVVeHVNDLETFIQCCCKVLKPGGSLFITTIN 251 56666777788843.3444311689886665442689998887755426899********************9886 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (219 nodes) Target sequences: 21272 (11266248 residues searched) Passed MSV filter: 469 (0.0220478); expected 425.4 (0.02) Passed bias filter: 337 (0.0158424); expected 425.4 (0.02) Passed Vit filter: 24 (0.00112824); expected 21.3 (0.001) Passed Fwd filter: 6 (0.000282061); expected 0.2 (1e-05) Initial search space (Z): 21272 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.18u 0.01s 00:00:00.19 Elapsed: 00:00:00.08 # Mc/sec: 30841.35 // [ok]