# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Methyltransf_8.hmm.txt
# target sequence database:        proteomes/Monodelphis_domestica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Methyltransf_8  [M=219]
Accession:   PF05148.15
Description: Hypothetical methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    2.3e-05   24.6   0.1    0.00012   22.2   0.1    1.9  1  tr|H9H5X9|H9H5X9_MONDO  Methyltransferase like 7B OS=Monodelp
    5.4e-05   23.4   0.0    9.5e-05   22.6   0.0    1.3  1  tr|F6ZD81|F6ZD81_MONDO  AlkB homolog 8, tRNA methyltransferas
    0.00026   21.2   0.0     0.0027   17.8   0.0    2.5  2  tr|F6WVA7|F6WVA7_MONDO  2-methoxy-6-polyprenyl-1,4-benzoquino
     0.0023   18.1   0.0      0.005   17.0   0.0    1.5  1  tr|F7A935|F7A935_MONDO  Uncharacterized protein OS=Monodelphi
  ------ inclusion threshold ------
       0.07   13.2   0.0       0.11   12.5   0.0    1.3  1  tr|F7FNN5|F7FNN5_MONDO  Uncharacterized protein OS=Monodelphi
       0.25   11.4   0.3       0.76    9.8   0.3    1.7  1  tr|F7F1Z8|F7F1Z8_MONDO  Ubiquinone biosynthesis O-methyltrans


Domain annotation for each sequence (and alignments):
>> tr|H9H5X9|H9H5X9_MONDO  Methyltransferase like 7B OS=Monodelphis domestica OX=13616 GN=METTL7B PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.1   3.5e-08   0.00012     112     156 ..     129     172 ..      47     178 .. 0.88

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 3.5e-08
                             -TTS-S--TT-EEEEEEES---SS-.HHHHHHHHHHHEEEEEEEEE CS
          Methyltransf_8 112 dlakvPledesvdvavfclslmgtn.ladflkeanrvlkvGGllkv 156
                             d+++v  +d+s+dv+v+ l l + +   + l+e++rvlk+GG+++ 
  tr|H9H5X9|H9H5X9_MONDO 129 DMSQV--ADGSMDVVVCTLVLCSVQsPSKVLQEVQRVLKPGGIFFF 172
                             66665..8*************8655167899***********9875 PP

>> tr|F6ZD81|F6ZD81_MONDO  AlkB homolog 8, tRNA methyltransferase OS=Monodelphis domestica OX=13616 GN=ALKBH8 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.6   0.0   2.7e-08   9.5e-05      56     155 ..     399     509 ..     363     529 .. 0.71

  Alignments for each domain:
  == domain 1  score: 22.6 bits;  conditional E-value: 2.7e-08
                             SS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..E...EEEESS-S....STTEEES-TTS-S--TT-EE....EEEEES- CS
          Methyltransf_8  56 PenPldviirklkkkkdnlvvadlGcGeakiaeavrekekv...rsfdlvav....nervvacdlakvPledesvd....vavfcls 131
                              + P  +i+  lk  ++  vvad+GcG+ k     ++   v   rs +lv +    + +  +cd   vP+  e+ d    +av+   
  tr|F6ZD81|F6ZD81_MONDO 399 RHTPWPQIVAFLKALPKGSVVADIGCGNGKYLGLSKDIYMVgcdRSQNLVEIcgerQFEAFVCDALAVPIRSETCDacisIAVIHHF 485
                             4578899***********************87555555555333677888753211234679*********9999844223333333 PP

                             --SS-HHHHHHHHHHHEEEEEEEE CS
          Methyltransf_8 132 lmgtnladflkeanrvlkvGGllk 155
                               ++     l+e  r+l++GG   
  tr|F6ZD81|F6ZD81_MONDO 486 ATAERRLATLQELARLLRPGGKAL 509
                             3445556789***********754 PP

>> tr|F6WVA7|F6WVA7_MONDO  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Monodelphis domestica OX=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   7.6e-07    0.0027     109     158 ..     187     237 ..     155     250 .. 0.88
   2 ?   -0.8   0.0      0.39   1.4e+03     156     184 ..     275     303 ..     269     309 .. 0.79

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 7.6e-07
                             EES-TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEE CS
          Methyltransf_8 109 vacdlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkvae 158
                             v+ d  ++P +d+  d+  + + +  +t +   l+ea+rvlk+GG +   e
  tr|F6WVA7|F6WVA7_MONDO 187 VVGDAEELPFDDDKFDIYTIAFGIRnVTHIDRALQEAYRVLKPGGRFLCLE 237
                             567999***********999999853899****************987666 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.39
                             EEEEGGG-S-HHHHHHHHHCTTEEEEEEE CS
          Methyltransf_8 156 vaevksrfesvklfaraltklGfevkskd 184
                             + e   rf+  + f++ ++  Gf+ +  +
  tr|F6WVA7|F6WVA7_MONDO 275 LVESIRRFPPQEEFKEMIEDAGFQKVTYE 303
                             55666799999************987665 PP

>> tr|F7A935|F7A935_MONDO  Uncharacterized protein OS=Monodelphis domestica OX=13616 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   1.4e-06     0.005     114     156 ..      19      61 ..      14      96 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 1.4e-06
                             TS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEEEEEE CS
          Methyltransf_8 114 akvPledesvdvavfclslmgtnladflkeanrvlkvGGllkv 156
                              k+Pled+svdv    +++   +   fl e++rvlk+ G +  
  tr|F7A935|F7A935_MONDO  19 EKLPLEDDSVDVLTAFVAIHWFDKVPFLMEVERVLKPHGCVAF 61 
                             689**********************************998755 PP

>> tr|F7FNN5|F7FNN5_MONDO  Uncharacterized protein OS=Monodelphis domestica OX=13616 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   3.2e-05      0.11     102     156 ..      48     106 ..      15     121 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 3.2e-05
                             S-SSTTEEES-TTS-S--TT-EEEEEEES--..-SS..-HHHHHHHHHHHEEEEEEEEE CS
          Methyltransf_8 102 vavnervvacdlakvPledesvdvavfclsl..mgt..nladflkeanrvlkvGGllkv 156
                             ++ + +v +cd  ++P  d+s d ++    +   +t    +  ++e+ rvl +GG +++
  tr|F7FNN5|F7FNN5_MONDO  48 HSRGCEVLVCDNLRLPFRDHSFDAVISIGVIhhFSTiqRRTRAVQEMARVLAPGGRVMI 106
                             456779*****************7765432211222113345789**********8776 PP

>> tr|F7F1Z8|F7F1Z8_MONDO  Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Monodelphis domestica OX=13616 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.3   0.00021      0.76      89     160 ..     177     251 ..     115     268 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00021
                             H--S-..EEEEESS-SSTTE..EES-TTS-S--.TT-EEEEEEES--.-SS-HHHHHHHHHHHEEEEEEEEEEEEG CS
          Methyltransf_8  89 avrekekvrsfdlvavnerv..vacdlakvPle.desvdvavfclsl.mgtnladflkeanrvlkvGGllkvaevk 160
                             +++  ++ +sfd   +++r+   ac l  +  e  es d +v    +  +++l++f++   +vlk+GG l+++ ++
  tr|F7F1Z8|F7F1Z8_MONDO 177 NIKTAQQHKSFDPI-LDKRIqyKACILEDIVEEtAESFDAVVASEVVeHVNDLETFIQCCCKVLKPGGSLFITTIN 251
                             56666777788843.3444311689886665442689998887755426899********************9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (219 nodes)
Target sequences:                        21272  (11266248 residues searched)
Passed MSV filter:                       469  (0.0220478); expected 425.4 (0.02)
Passed bias filter:                      337  (0.0158424); expected 425.4 (0.02)
Passed Vit filter:                        24  (0.00112824); expected 21.3 (0.001)
Passed Fwd filter:                         6  (0.000282061); expected 0.2 (1e-05)
Initial search space (Z):              21272  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.18u 0.01s 00:00:00.19 Elapsed: 00:00:00.08
# Mc/sec: 30841.35
//
[ok]