# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Methyltransf_8.hmm.txt
# target sequence database:        proteomes/Mus_musculus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Methyltransf_8  [M=219]
Accession:   PF05148.15
Description: Hypothetical methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
   4.1e-104  347.5   0.0   5.3e-104  347.1   0.0    1.1  1  sp|Q9DB85|RRP8_MOUSE    Ribosomal RNA-processing protein 8 OS
    2.1e-06   28.1   0.0    0.00011   22.5   0.0    2.1  2  sp|Q9DD20|MET7B_MOUSE   Methyltransferase-like protein 7B OS=
    2.4e-06   27.9   0.0    3.6e-06   27.3   0.0    1.3  1  tr|G3X9G9|G3X9G9_MOUSE  MCG123521, isoform CRA_a OS=Mus muscu
    2.7e-06   27.7   0.0    3.9e-06   27.2   0.0    1.3  1  tr|Q5I0W6|Q5I0W6_MOUSE  Methyltransferase-like 7A2 OS=Mus mus
    4.9e-06   26.9   0.0      8e-06   26.2   0.0    1.3  1  tr|Q8C6B0|Q8C6B0_MOUSE  MCG20149, isoform CRA_a OS=Mus muscul
    6.1e-06   26.6   0.0      1e-05   25.9   0.0    1.3  1  sp|Q80WQ4|TRM9B_MOUSE   Probable tRNA methyltransferase 9B OS
    2.6e-05   24.5   0.0    4.5e-05   23.7   0.0    1.3  1  sp|Q80Y20|ALKB8_MOUSE   Alkylated DNA repair protein alkB hom
    3.8e-05   23.9   0.0    0.00099   19.3   0.0    2.4  3  sp|Q91WU5|AS3MT_MOUSE   Arsenite methyltransferase OS=Mus mus
    0.00039   20.6   0.0      0.001   19.3   0.0    1.8  2  sp|Q9CXI0|COQ5_MOUSE    2-methoxy-6-polyprenyl-1,4-benzoquino
     0.0059   16.8   0.1       0.01   16.0   0.1    1.3  1  tr|Q76I26|Q76I26_MOUSE  Methyltransferase hypoxia-inducible d
  ------ inclusion threshold ------
      0.017   15.3   0.0      0.042   14.0   0.0    1.7  1  sp|A2APY7|NDUF5_MOUSE   Arginine-hydroxylase NDUFAF5, mitocho
      0.047   13.9   0.0       0.26   11.4   0.0    2.0  2  sp|Q9CZB3|THUM2_MOUSE   THUMP domain-containing protein 2 OS=
      0.058   13.5   0.0      0.097   12.8   0.0    1.3  1  sp|Q8CAE2|HENMT_MOUSE   Small RNA 2'-O-methyltransferase OS=M
       0.18   12.0   0.0       0.32   11.1   0.0    1.3  1  sp|Q8BMK1|METL2_MOUSE   Methyltransferase-like protein 2 OS=M
       0.23   11.6   0.0       0.39   10.8   0.0    1.3  1  tr|Q8BGM4|Q8BGM4_MOUSE  Methyltransferase-like 27 OS=Mus musc


Domain annotation for each sequence (and alignments):
>> sp|Q9DB85|RRP8_MOUSE  Ribosomal RNA-processing protein 8 OS=Mus musculus OX=10090 GN=Rrp8 PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  347.1   0.0  3.6e-107  5.3e-104       2     219 .]     239     457 .]     238     457 .] 0.99

  Alignments for each domain:
  == domain 1  score: 347.1 bits;  conditional E-value: 3.6e-107
                           XXXXX-HHHHHHHHHHHHHHHHHS-HHHHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH- CS
        Methyltransf_8   2 leakikkrldgarfrflneklytgesskavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeav 90 
                           l+a++++rldgarfr+lne+ly+g+ss+a +lf+edpeaf lyh+gf+ qvkkWP +P+d+i+++l++k+++lvvad+GcG++++a++v
  sp|Q9DB85|RRP8_MOUSE 239 LRARMTQRLDGARFRYLNEQLYSGPSSAARRLFQEDPEAFLLYHRGFQRQVKKWPLHPVDRIAKDLRQKPASLVVADFGCGDCRLASSV 327
                           899************************************************************************************** PP

                           -S-..EEEEESS-SSTTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S-HHHHHHHHHCTTEE CS
        Methyltransf_8  91 rekekvrsfdlvavnervvacdlakvPledesvdvavfclslmgtnladflkeanrvlkvGGllkvaevksrfesvklfaraltklGfe 179
                           r++  v++fdl+++++rv++cd+a+vPledesvdvavfclslmgtn++dfl+eanrvlk+GGllkvaev+srfe++++f+ a+tklGf+
  sp|Q9DB85|RRP8_MOUSE 328 RNP--VHCFDLASLDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKTGGLLKVAEVSSRFEDIRTFLGAVTKLGFK 414
                           **9..************************************************************************************ PP

                           EEEEE--STTEEEEEEEE-S..SS-TT---.GG--------XX CS
        Methyltransf_8 180 vkskdlsnkqfvlfefkkve..kkgkkrel.glklkpclykkr 219
                           +  kdl+n++f+lf+f+k++  ++g+k++l glkl+pclyk+r
  sp|Q9DB85|RRP8_MOUSE 415 IIYKDLTNSHFFLFDFEKTGppRVGPKAQLsGLKLQPCLYKRR 457
                           *******************8889******999**********9 PP

>> sp|Q9DD20|MET7B_MOUSE  Methyltransferase-like protein 7B OS=Mus musculus OX=10090 GN=Mettl7b PE=1 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0     0.041        61      63     100 ..      61      98 ..      44     115 .. 0.77
   2 !   22.5   0.0   7.2e-08   0.00011     118     158 ..     133     174 ..     120     192 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.041
                            HHHHHCTS-TTS-EEEES-TT-HHHHH--S-..EEEEE CS
         Methyltransf_8  63 iirklkkkkdnlvvadlGcGeakiaeavrekekvrsfd 100
                             i++lk   +n+++ +lGcG     +   +  kv ++d
  sp|Q9DD20|MET7B_MOUSE  61 QIKDLKGTSGNVALLELGCGTGANFQFYPQGCKVTCVD 98 
                            58999***************865554555555666666 PP

  == domain 2  score: 22.5 bits;  conditional E-value: 7.2e-08
                            --TT-EEEEEEES---S.S-HHHHHHHHHHHEEEEEEEEEEE CS
         Methyltransf_8 118 ledesvdvavfclslmg.tnladflkeanrvlkvGGllkvae 158
                            l+d+s+dv+v+ l l + +  ++ l+e++rvl++GGll+  e
  sp|Q9DD20|MET7B_MOUSE 133 LADSSMDVVVCTLVLCSvQSPRKVLQEVQRVLRPGGLLFFWE 174
                            79************9861567999*************98655 PP

>> tr|G3X9G9|G3X9G9_MOUSE  MCG123521, isoform CRA_a OS=Mus musculus OX=10090 GN=Mettl7a3 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.0   2.4e-09   3.6e-06     112     179 ..     129     200 ..     117     240 .. 0.63

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 2.4e-09
                             -TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEE....EEEEGGG-S.-HHHHHHHHHCTTEE CS
          Methyltransf_8 112 dlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllk....vaevksrfe.svklfaraltklGfe 179
                             d+ +v   d+svdv+v+ l l  ++n ++ l+e+ rvlk+GG ++    va+ +s  +   ++++ ++  l f+
  tr|G3X9G9|G3X9G9_MOUSE 129 DMHQV--TDGSVDVVVCTLVLCsVKNQEKILREVCRVLKPGGAFYfidhVADERSTWNyFWQQVLARVWFLAFD 200
                             56655..7************973689999*************98632223444444442233444444455555 PP

>> tr|Q5I0W6|Q5I0W6_MOUSE  Methyltransferase-like 7A2 OS=Mus musculus OX=10090 GN=Mettl7a2 PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   0.0   2.7e-09   3.9e-06     112     179 ..     129     200 ..     117     240 .. 0.63

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 2.7e-09
                             -TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEE....EEEEGGG-S.-HHHHHHHHHCTTEE CS
          Methyltransf_8 112 dlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllk....vaevksrfe.svklfaraltklGfe 179
                             d+ +v   d+svdv+v+ l l  ++n ++ l+e+ rvlk+GG ++    va+ +s  +   ++++ ++  l f+
  tr|Q5I0W6|Q5I0W6_MOUSE 129 DMHQV--TDGSVDVVVCTLVLCsVKNQEKILREVCRVLKPGGAFYfidhVADERSTWNyFWQQVLARVWFLAFD 200
                             55554..7************973689999*************98632223444444442233444444455555 PP

>> tr|Q8C6B0|Q8C6B0_MOUSE  MCG20149, isoform CRA_a OS=Mus musculus OX=10090 GN=Mettl7a1 PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   0.0   5.4e-09     8e-06     112     158 ..     129     174 ..     117     197 .. 0.83

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 5.4e-09
                             -TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEE CS
          Methyltransf_8 112 dlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkvae 158
                             d+ +v   d+svdv+v+ l l  ++n ++ l+e+ rvlk+GG ++  e
  tr|Q8C6B0|Q8C6B0_MOUSE 129 DMHQV--TDGSVDVVVCTLVLCsVKNQEKILREVCRVLKPGGAFYFME 174
                             55554..7************973689999*************999776 PP

>> sp|Q80WQ4|TRM9B_MOUSE  Probable tRNA methyltransferase 9B OS=Mus musculus OX=10090 GN=Trmt9b PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.0   6.7e-09     1e-05      50     156 ..      27     139 ..       4     158 .. 0.69

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 6.7e-09
                            HHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..EEE...EESS-SST....TEEES-TTS-S--TT-EEEEEE.. CS
         Methyltransf_8  50 sqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeavrekekvrs...fdlvavne....rvvacdlakvPledesvdvavf.. 128
                             q k WP   +    + l+ +k    vad+GcG  k  +  ++ + + +     lv +      +v++cd  ++P  d+  d ++   
  sp|Q80WQ4|TRM9B_MOUSE  27 LQSKAWPR--V---RQFLQDQKPGSLVADIGCGTGKYLKVNSQVHTLGCdycGPLVEIARnrgcEVMVCDNLNLPFRDQGFDAIISig 109
                            46777774..4...4556667777889*********99666666666542113455443222337***************99655411 PP

                            ES---SS-HH..HHHHHHHHHEEEEEEEEE CS
         Methyltransf_8 129 clslmgtnla..dflkeanrvlkvGGllkv 156
                             +   +t+ +    +ke+ rvl +GG l++
  sp|Q80WQ4|TRM9B_MOUSE 110 VIHHFSTKERriRAIKEMARVLAPGGQLMI 139
                            344444443311579***********9987 PP

>> sp|Q80Y20|ALKB8_MOUSE  Alkylated DNA repair protein alkB homolog 8 OS=Mus musculus OX=10090 GN=Alkbh8 PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.0     3e-08   4.5e-05      29     155 ..     366     500 ..     359     522 .. 0.70

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 3e-08
                            HHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..E...EEEESS-S....STTEE CS
         Methyltransf_8  29 kavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeavrekekv...rsfdlvav....nervv 109
                            +a +l  e+ ++ ++y +  +s      + P  +i++ lk  ++  +vad+GcG+ k     ++   +   rs +lv +    + +  
  sp|Q80Y20|ALKB8_MOUSE 366 EALEL--EQKHVHQVYNEI-ASHFSSTRHSPWPRIVEFLKALPSGSIVADIGCGNGKYLGINKDLYMIgcdRSQNLVDIcrerQFQAL 450
                            44445..666677777654.4556666788999************************8744444444422244555554211134678 PP

                            ES-TTS-S--TT-EE....EEEEES---SS-HHHHHHHHHHHEEEEEEEE CS
         Methyltransf_8 110 acdlakvPledesvd....vavfclslmgtnladflkeanrvlkvGGllk 155
                            +cd   vP+  +s d    +av+     ++   + l+e  r+l++GG   
  sp|Q80Y20|ALKB8_MOUSE 451 VCDALAVPVRSGSCDacisIAVIHHFATAERRVEALQELARLLRPGGQAL 500
                            9*********9998844223444444445566789************754 PP

>> sp|Q91WU5|AS3MT_MOUSE  Arsenite methyltransferase OS=Mus musculus OX=10090 GN=As3mt PE=1 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0      0.18   2.7e+02      69     109 ..      68     112 ..      38     126 .. 0.80
   2 !   19.3   0.0   6.6e-07   0.00099     114     164 ..     141     192 ..     117     202 .. 0.84
   3 ?   -2.6   0.0       3.3   4.9e+03     186     205 ..     254     273 ..     248     277 .. 0.82

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.18
                            TS-TTS-EEEES-TT-H....HHHH--S-..EEEEESS-SSTTEE CS
         Methyltransf_8  69 kkkdnlvvadlGcGeak....iaeavrekekvrsfdlvavnervv 109
                            ++ +n  + dlG G  +    +++ v+ek +v  +d++ v+ +v 
  sp|Q91WU5|AS3MT_MOUSE  68 ERLENCRILDLGSGSGRdcyvLSQLVGEKGHVTGIDMTEVQVEVA 112
                            677899999***997763333347789999999999999988776 PP

  == domain 2  score: 19.3 bits;  conditional E-value: 6.6e-07
                            TS-S--TT-EEEEEE.ES---SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S CS
         Methyltransf_8 114 akvPledesvdvavf.clslmgtnladflkeanrvlkvGGllkvaevksrfe 164
                            a+  ++ es d+++  c+  ++ + ++ l+e++rvlk GG l+ ++v + +e
  sp|Q91WU5|AS3MT_MOUSE 141 AEAGIQSESYDIVISnCVINLVPDKQQVLQEVYRVLKHGGELYFSDVYASLE 192
                            45567899****995499999***********************99987665 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 3.3
                            -STTEEEEEEEE-SSS-TT- CS
         Methyltransf_8 186 snkqfvlfefkkvekkgkkr 205
                             +++f lf++ k+e  +++r
  sp|Q91WU5|AS3MT_MOUSE 254 VSATFRLFKLPKTEPAERCR 273
                            567899******99999887 PP

>> sp|Q9CXI0|COQ5_MOUSE  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Mus musculus OX=10090 GN=Coq
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.0   6.7e-07     0.001     109     157 ..     196     245 ..     148     266 .. 0.85
   2 ?   -3.5   0.0       6.2   9.2e+03     158     182 ..     286     310 ..     280     316 .. 0.70

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 6.7e-07
                           EES-TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEE CS
        Methyltransf_8 109 vacdlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkva 157
                           v  d  ++P +d+s dv  + + +  +t + + l+ea+rvlk+GG +   
  sp|Q9CXI0|COQ5_MOUSE 196 VLGDAEELPFDDDSFDVYTIAFGIRnVTHIDQALQEAHRVLKPGGRFLCL 245
                           5568899**********99999985389*****************87655 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 6.2
                           EEGGG-S-HHHHHHHHHCTTEEEEE CS
        Methyltransf_8 158 evksrfesvklfaraltklGfevks 182
                           e   +f++ + f+  ++  Gf+ + 
  sp|Q9CXI0|COQ5_MOUSE 286 ESIRKFPNQEDFKDMIEDAGFQRVT 310
                           4455788888888888888887665 PP

>> tr|Q76I26|Q76I26_MOUSE  Methyltransferase hypoxia-inducible domain-containing 1 OS=Mus musculus OX=10090 GN=Methig1 P
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.1   6.8e-06      0.01     112     150 ..     129     166 ..     117     182 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 6.8e-06
                             -TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEE CS
          Methyltransf_8 112 dlakvPledesvdvavfclslm.gtnladflkeanrvlkv 150
                             d+ +v   d+svdv+v+ l l  ++n ++ l+e+ rvlk+
  tr|Q76I26|Q76I26_MOUSE 129 DMHQV--TDGSVDVVVCTLVLCsVKNQEKILREVCRVLKP 166
                             55554..7************973689999*********96 PP

>> sp|A2APY7|NDUF5_MOUSE  Arginine-hydroxylase NDUFAF5, mitochondrial OS=Mus musculus OX=10090 GN=Ndufaf5 PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   2.8e-05     0.042      76     154 ..      93     184 ..      39     189 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 2.8e-05
                            EEEES-TT-HHHHH--S..-..EEEEESS......-SSTTEEES-T....TS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEE CS
         Methyltransf_8  76 vadlGcGeakiaeavre..kekvrsfdlv......avnervvacdl....akvPledesvdvavfclslm.gtnladflkeanrvlkv 150
                              d+GcG   ia++  +    k+   d++      +++ ++ + ++      +P ++++ d++v  lsl  +++l   l++++ vlk+
  sp|A2APY7|NDUF5_MOUSE  93 ALDIGCGRGYIAQHLDKetVGKIFQTDIAehalknSLETDIPTVNIladeEFLPFQENTFDLVVSSLSLHwVNDLPRALEQIHYVLKP 180
                            579*********65544114567777764221112344454444333211669****************64899************** PP

                            EEEE CS
         Methyltransf_8 151 GGll 154
                             G++
  sp|A2APY7|NDUF5_MOUSE 181 DGVF 184
                            9987 PP

>> sp|Q9CZB3|THUM2_MOUSE  THUMP domain-containing protein 2 OS=Mus musculus OX=10090 GN=Thumpd2 PE=2 SV=3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.93   1.4e+03       4      33 ..      32      61 ..      30      83 .. 0.74
   2 ?   11.4   0.0   0.00018      0.26     113     155 ..     358     405 ..     341     415 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.93
                           XXX-HHHHHHHHHHHHHHHHHS-HHHHHHH CS
         Methyltransf_8  4 akikkrldgarfrflneklytgesskavdl 33
                           ++++ rl++++  ++  k++ ++ s    +
  sp|Q9CZB3|THUM2_MOUSE 32 REVRARLEATQVEYISGKVFFTTCSDLPSM 61
                           67899*************998887765554 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00018
                            TTS-S--TT-EEEEEEES--.....-SS-HHHHHHHHHHHEEEEEEEE CS
         Methyltransf_8 113 lakvPledesvdvavfclsl.....mgtnladflkeanrvlkvGGllk 155
                            ++ +Pl  +s dv++  + +     +g+++++ l+e++rvl+vGG + 
  sp|Q9CZB3|THUM2_MOUSE 358 VTDLPLPSQSTDVIISDIPFgkkfkLGKDIKSILQEMERVLRVGGAMV 405
                            677899999999998776543344489******************875 PP

>> sp|Q8CAE2|HENMT_MOUSE  Small RNA 2'-O-methyltransferase OS=Mus musculus OX=10090 GN=Henmt1 PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   6.5e-05     0.097      62      87 ..      38      63 ..      28      82 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.5e-05
                           HHHHHHCTS-TTS-EEEES-TT-HHH CS
         Methyltransf_8 62 viirklkkkkdnlvvadlGcGeakia 87
                           +++r+l  +++ + vadlGcG+ak+ 
  sp|Q8CAE2|HENMT_MOUSE 38 QFVRDLVDRHEPKKVADLGCGDAKLL 63
                           68999*******************96 PP

>> sp|Q8BMK1|METL2_MOUSE  Methyltransferase-like protein 2 OS=Mus musculus OX=10090 GN=Mettl2 PE=2 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00021      0.32     111     155 ..     234     282 ..     226     299 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00021
                            S-T.TS-S--TT-EEEEE..EES---S.S-HHHHHHHHHHHEEEEEEEE CS
         Methyltransf_8 111 cdl.akvPledesvdvav..fclslmg.tnladflkeanrvlkvGGllk 155
                            cd  +  P+ ++s dv+v  f ls ++ +++++ +    r+lk+GG++ 
  sp|Q8BMK1|METL2_MOUSE 234 CDEdQSYPVPEDSLDVIVliFVLSAIVpDKMQKAISKLSRLLKPGGVML 282
                            777566789999999865338899776266999*************986 PP

>> tr|Q8BGM4|Q8BGM4_MOUSE  Methyltransferase-like 27 OS=Mus musculus OX=10090 GN=Mettl27 PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00026      0.39      56     156 ..      51     166 ..      38     189 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00026
                             SS-HHHHHHHHHCTS-TTS-EEEES-TT-HHH..HH--S-..EEEEE.....SS-.....SSTTEEES-TTS-S--T..T-EEEEEE CS
          Methyltransf_8  56 PenPldviirklkkkkdnlvvadlGcGeakia..eavrekekvrsfd.....lva.....vnervvacdlakvPled..esvdvavf 128
                             P   +d + r ++  +++  + d+ cG   +a   + r + +v+ +d     l+      + +++  c l + Pl d  ++ d +++
  tr|Q8BGM4|Q8BGM4_MOUSE  51 PRLAVDCLSRAFRGSPHDALILDVACGTGLVAveLQARGFLQVQGVDgspemLKQarargLYHHLSLCTLGQEPLPDpeGTFDAVII 137
                             7778999************************9655678899***9994443322112222457889999988777764378998888 PP

                             ES---SS-H.HHHHHHHHHHEEEEEEEEE CS
          Methyltransf_8 129 clslmgtnl.adflkeanrvlkvGGllkv 156
                               +l   ++  + + e  rv k+GGl+ +
  tr|Q8BGM4|Q8BGM4_MOUSE 138 VGALSEGQVpCSAIPELLRVTKPGGLVCL 166
                             88877555526899999*******99765 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (219 nodes)
Target sequences:                        22289  (11757923 residues searched)
Passed MSV filter:                       509  (0.0228364); expected 445.8 (0.02)
Passed bias filter:                      371  (0.016645); expected 445.8 (0.02)
Passed Vit filter:                        39  (0.00174974); expected 22.3 (0.001)
Passed Fwd filter:                        15  (0.000672978); expected 0.2 (1e-05)
Initial search space (Z):              22289  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.18u 0.01s 00:00:00.19 Elapsed: 00:00:00.08
# Mc/sec: 32187.31
//
[ok]