# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_8.hmm.txt # target sequence database: proteomes/Mus_musculus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_8 [M=219] Accession: PF05148.15 Description: Hypothetical methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-104 347.5 0.0 5.3e-104 347.1 0.0 1.1 1 sp|Q9DB85|RRP8_MOUSE Ribosomal RNA-processing protein 8 OS 2.1e-06 28.1 0.0 0.00011 22.5 0.0 2.1 2 sp|Q9DD20|MET7B_MOUSE Methyltransferase-like protein 7B OS= 2.4e-06 27.9 0.0 3.6e-06 27.3 0.0 1.3 1 tr|G3X9G9|G3X9G9_MOUSE MCG123521, isoform CRA_a OS=Mus muscu 2.7e-06 27.7 0.0 3.9e-06 27.2 0.0 1.3 1 tr|Q5I0W6|Q5I0W6_MOUSE Methyltransferase-like 7A2 OS=Mus mus 4.9e-06 26.9 0.0 8e-06 26.2 0.0 1.3 1 tr|Q8C6B0|Q8C6B0_MOUSE MCG20149, isoform CRA_a OS=Mus muscul 6.1e-06 26.6 0.0 1e-05 25.9 0.0 1.3 1 sp|Q80WQ4|TRM9B_MOUSE Probable tRNA methyltransferase 9B OS 2.6e-05 24.5 0.0 4.5e-05 23.7 0.0 1.3 1 sp|Q80Y20|ALKB8_MOUSE Alkylated DNA repair protein alkB hom 3.8e-05 23.9 0.0 0.00099 19.3 0.0 2.4 3 sp|Q91WU5|AS3MT_MOUSE Arsenite methyltransferase OS=Mus mus 0.00039 20.6 0.0 0.001 19.3 0.0 1.8 2 sp|Q9CXI0|COQ5_MOUSE 2-methoxy-6-polyprenyl-1,4-benzoquino 0.0059 16.8 0.1 0.01 16.0 0.1 1.3 1 tr|Q76I26|Q76I26_MOUSE Methyltransferase hypoxia-inducible d ------ inclusion threshold ------ 0.017 15.3 0.0 0.042 14.0 0.0 1.7 1 sp|A2APY7|NDUF5_MOUSE Arginine-hydroxylase NDUFAF5, mitocho 0.047 13.9 0.0 0.26 11.4 0.0 2.0 2 sp|Q9CZB3|THUM2_MOUSE THUMP domain-containing protein 2 OS= 0.058 13.5 0.0 0.097 12.8 0.0 1.3 1 sp|Q8CAE2|HENMT_MOUSE Small RNA 2'-O-methyltransferase OS=M 0.18 12.0 0.0 0.32 11.1 0.0 1.3 1 sp|Q8BMK1|METL2_MOUSE Methyltransferase-like protein 2 OS=M 0.23 11.6 0.0 0.39 10.8 0.0 1.3 1 tr|Q8BGM4|Q8BGM4_MOUSE Methyltransferase-like 27 OS=Mus musc Domain annotation for each sequence (and alignments): >> sp|Q9DB85|RRP8_MOUSE Ribosomal RNA-processing protein 8 OS=Mus musculus OX=10090 GN=Rrp8 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 347.1 0.0 3.6e-107 5.3e-104 2 219 .] 239 457 .] 238 457 .] 0.99 Alignments for each domain: == domain 1 score: 347.1 bits; conditional E-value: 3.6e-107 XXXXX-HHHHHHHHHHHHHHHHHS-HHHHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH- CS Methyltransf_8 2 leakikkrldgarfrflneklytgesskavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeav 90 l+a++++rldgarfr+lne+ly+g+ss+a +lf+edpeaf lyh+gf+ qvkkWP +P+d+i+++l++k+++lvvad+GcG++++a++v sp|Q9DB85|RRP8_MOUSE 239 LRARMTQRLDGARFRYLNEQLYSGPSSAARRLFQEDPEAFLLYHRGFQRQVKKWPLHPVDRIAKDLRQKPASLVVADFGCGDCRLASSV 327 899************************************************************************************** PP -S-..EEEEESS-SSTTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S-HHHHHHHHHCTTEE CS Methyltransf_8 91 rekekvrsfdlvavnervvacdlakvPledesvdvavfclslmgtnladflkeanrvlkvGGllkvaevksrfesvklfaraltklGfe 179 r++ v++fdl+++++rv++cd+a+vPledesvdvavfclslmgtn++dfl+eanrvlk+GGllkvaev+srfe++++f+ a+tklGf+ sp|Q9DB85|RRP8_MOUSE 328 RNP--VHCFDLASLDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKTGGLLKVAEVSSRFEDIRTFLGAVTKLGFK 414 **9..************************************************************************************ PP EEEEE--STTEEEEEEEE-S..SS-TT---.GG--------XX CS Methyltransf_8 180 vkskdlsnkqfvlfefkkve..kkgkkrel.glklkpclykkr 219 + kdl+n++f+lf+f+k++ ++g+k++l glkl+pclyk+r sp|Q9DB85|RRP8_MOUSE 415 IIYKDLTNSHFFLFDFEKTGppRVGPKAQLsGLKLQPCLYKRR 457 *******************8889******999**********9 PP >> sp|Q9DD20|MET7B_MOUSE Methyltransferase-like protein 7B OS=Mus musculus OX=10090 GN=Mettl7b PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.7 0.0 0.041 61 63 100 .. 61 98 .. 44 115 .. 0.77 2 ! 22.5 0.0 7.2e-08 0.00011 118 158 .. 133 174 .. 120 192 .. 0.85 Alignments for each domain: == domain 1 score: 3.7 bits; conditional E-value: 0.041 HHHHHCTS-TTS-EEEES-TT-HHHHH--S-..EEEEE CS Methyltransf_8 63 iirklkkkkdnlvvadlGcGeakiaeavrekekvrsfd 100 i++lk +n+++ +lGcG + + kv ++d sp|Q9DD20|MET7B_MOUSE 61 QIKDLKGTSGNVALLELGCGTGANFQFYPQGCKVTCVD 98 58999***************865554555555666666 PP == domain 2 score: 22.5 bits; conditional E-value: 7.2e-08 --TT-EEEEEEES---S.S-HHHHHHHHHHHEEEEEEEEEEE CS Methyltransf_8 118 ledesvdvavfclslmg.tnladflkeanrvlkvGGllkvae 158 l+d+s+dv+v+ l l + + ++ l+e++rvl++GGll+ e sp|Q9DD20|MET7B_MOUSE 133 LADSSMDVVVCTLVLCSvQSPRKVLQEVQRVLRPGGLLFFWE 174 79************9861567999*************98655 PP >> tr|G3X9G9|G3X9G9_MOUSE MCG123521, isoform CRA_a OS=Mus musculus OX=10090 GN=Mettl7a3 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.3 0.0 2.4e-09 3.6e-06 112 179 .. 129 200 .. 117 240 .. 0.63 Alignments for each domain: == domain 1 score: 27.3 bits; conditional E-value: 2.4e-09 -TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEE....EEEEGGG-S.-HHHHHHHHHCTTEE CS Methyltransf_8 112 dlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllk....vaevksrfe.svklfaraltklGfe 179 d+ +v d+svdv+v+ l l ++n ++ l+e+ rvlk+GG ++ va+ +s + ++++ ++ l f+ tr|G3X9G9|G3X9G9_MOUSE 129 DMHQV--TDGSVDVVVCTLVLCsVKNQEKILREVCRVLKPGGAFYfidhVADERSTWNyFWQQVLARVWFLAFD 200 56655..7************973689999*************98632223444444442233444444455555 PP >> tr|Q5I0W6|Q5I0W6_MOUSE Methyltransferase-like 7A2 OS=Mus musculus OX=10090 GN=Mettl7a2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.2 0.0 2.7e-09 3.9e-06 112 179 .. 129 200 .. 117 240 .. 0.63 Alignments for each domain: == domain 1 score: 27.2 bits; conditional E-value: 2.7e-09 -TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEE....EEEEGGG-S.-HHHHHHHHHCTTEE CS Methyltransf_8 112 dlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllk....vaevksrfe.svklfaraltklGfe 179 d+ +v d+svdv+v+ l l ++n ++ l+e+ rvlk+GG ++ va+ +s + ++++ ++ l f+ tr|Q5I0W6|Q5I0W6_MOUSE 129 DMHQV--TDGSVDVVVCTLVLCsVKNQEKILREVCRVLKPGGAFYfidhVADERSTWNyFWQQVLARVWFLAFD 200 55554..7************973689999*************98632223444444442233444444455555 PP >> tr|Q8C6B0|Q8C6B0_MOUSE MCG20149, isoform CRA_a OS=Mus musculus OX=10090 GN=Mettl7a1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.2 0.0 5.4e-09 8e-06 112 158 .. 129 174 .. 117 197 .. 0.83 Alignments for each domain: == domain 1 score: 26.2 bits; conditional E-value: 5.4e-09 -TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEE CS Methyltransf_8 112 dlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkvae 158 d+ +v d+svdv+v+ l l ++n ++ l+e+ rvlk+GG ++ e tr|Q8C6B0|Q8C6B0_MOUSE 129 DMHQV--TDGSVDVVVCTLVLCsVKNQEKILREVCRVLKPGGAFYFME 174 55554..7************973689999*************999776 PP >> sp|Q80WQ4|TRM9B_MOUSE Probable tRNA methyltransferase 9B OS=Mus musculus OX=10090 GN=Trmt9b PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.0 6.7e-09 1e-05 50 156 .. 27 139 .. 4 158 .. 0.69 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 6.7e-09 HHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..EEE...EESS-SST....TEEES-TTS-S--TT-EEEEEE.. CS Methyltransf_8 50 sqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeavrekekvrs...fdlvavne....rvvacdlakvPledesvdvavf.. 128 q k WP + + l+ +k vad+GcG k + ++ + + + lv + +v++cd ++P d+ d ++ sp|Q80WQ4|TRM9B_MOUSE 27 LQSKAWPR--V---RQFLQDQKPGSLVADIGCGTGKYLKVNSQVHTLGCdycGPLVEIARnrgcEVMVCDNLNLPFRDQGFDAIISig 109 46777774..4...4556667777889*********99666666666542113455443222337***************99655411 PP ES---SS-HH..HHHHHHHHHEEEEEEEEE CS Methyltransf_8 129 clslmgtnla..dflkeanrvlkvGGllkv 156 + +t+ + +ke+ rvl +GG l++ sp|Q80WQ4|TRM9B_MOUSE 110 VIHHFSTKERriRAIKEMARVLAPGGQLMI 139 344444443311579***********9987 PP >> sp|Q80Y20|ALKB8_MOUSE Alkylated DNA repair protein alkB homolog 8 OS=Mus musculus OX=10090 GN=Alkbh8 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.7 0.0 3e-08 4.5e-05 29 155 .. 366 500 .. 359 522 .. 0.70 Alignments for each domain: == domain 1 score: 23.7 bits; conditional E-value: 3e-08 HHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..E...EEEESS-S....STTEE CS Methyltransf_8 29 kavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeavrekekv...rsfdlvav....nervv 109 +a +l e+ ++ ++y + +s + P +i++ lk ++ +vad+GcG+ k ++ + rs +lv + + + sp|Q80Y20|ALKB8_MOUSE 366 EALEL--EQKHVHQVYNEI-ASHFSSTRHSPWPRIVEFLKALPSGSIVADIGCGNGKYLGINKDLYMIgcdRSQNLVDIcrerQFQAL 450 44445..666677777654.4556666788999************************8744444444422244555554211134678 PP ES-TTS-S--TT-EE....EEEEES---SS-HHHHHHHHHHHEEEEEEEE CS Methyltransf_8 110 acdlakvPledesvd....vavfclslmgtnladflkeanrvlkvGGllk 155 +cd vP+ +s d +av+ ++ + l+e r+l++GG sp|Q80Y20|ALKB8_MOUSE 451 VCDALAVPVRSGSCDacisIAVIHHFATAERRVEALQELARLLRPGGQAL 500 9*********9998844223444444445566789************754 PP >> sp|Q91WU5|AS3MT_MOUSE Arsenite methyltransferase OS=Mus musculus OX=10090 GN=As3mt PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 1.6 0.0 0.18 2.7e+02 69 109 .. 68 112 .. 38 126 .. 0.80 2 ! 19.3 0.0 6.6e-07 0.00099 114 164 .. 141 192 .. 117 202 .. 0.84 3 ? -2.6 0.0 3.3 4.9e+03 186 205 .. 254 273 .. 248 277 .. 0.82 Alignments for each domain: == domain 1 score: 1.6 bits; conditional E-value: 0.18 TS-TTS-EEEES-TT-H....HHHH--S-..EEEEESS-SSTTEE CS Methyltransf_8 69 kkkdnlvvadlGcGeak....iaeavrekekvrsfdlvavnervv 109 ++ +n + dlG G + +++ v+ek +v +d++ v+ +v sp|Q91WU5|AS3MT_MOUSE 68 ERLENCRILDLGSGSGRdcyvLSQLVGEKGHVTGIDMTEVQVEVA 112 677899999***997763333347789999999999999988776 PP == domain 2 score: 19.3 bits; conditional E-value: 6.6e-07 TS-S--TT-EEEEEE.ES---SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S CS Methyltransf_8 114 akvPledesvdvavf.clslmgtnladflkeanrvlkvGGllkvaevksrfe 164 a+ ++ es d+++ c+ ++ + ++ l+e++rvlk GG l+ ++v + +e sp|Q91WU5|AS3MT_MOUSE 141 AEAGIQSESYDIVISnCVINLVPDKQQVLQEVYRVLKHGGELYFSDVYASLE 192 45567899****995499999***********************99987665 PP == domain 3 score: -2.6 bits; conditional E-value: 3.3 -STTEEEEEEEE-SSS-TT- CS Methyltransf_8 186 snkqfvlfefkkvekkgkkr 205 +++f lf++ k+e +++r sp|Q91WU5|AS3MT_MOUSE 254 VSATFRLFKLPKTEPAERCR 273 567899******99999887 PP >> sp|Q9CXI0|COQ5_MOUSE 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Mus musculus OX=10090 GN=Coq # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 6.7e-07 0.001 109 157 .. 196 245 .. 148 266 .. 0.85 2 ? -3.5 0.0 6.2 9.2e+03 158 182 .. 286 310 .. 280 316 .. 0.70 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 6.7e-07 EES-TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEE CS Methyltransf_8 109 vacdlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkva 157 v d ++P +d+s dv + + + +t + + l+ea+rvlk+GG + sp|Q9CXI0|COQ5_MOUSE 196 VLGDAEELPFDDDSFDVYTIAFGIRnVTHIDQALQEAHRVLKPGGRFLCL 245 5568899**********99999985389*****************87655 PP == domain 2 score: -3.5 bits; conditional E-value: 6.2 EEGGG-S-HHHHHHHHHCTTEEEEE CS Methyltransf_8 158 evksrfesvklfaraltklGfevks 182 e +f++ + f+ ++ Gf+ + sp|Q9CXI0|COQ5_MOUSE 286 ESIRKFPNQEDFKDMIEDAGFQRVT 310 4455788888888888888887665 PP >> tr|Q76I26|Q76I26_MOUSE Methyltransferase hypoxia-inducible domain-containing 1 OS=Mus musculus OX=10090 GN=Methig1 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.1 6.8e-06 0.01 112 150 .. 129 166 .. 117 182 .. 0.85 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 6.8e-06 -TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEE CS Methyltransf_8 112 dlakvPledesvdvavfclslm.gtnladflkeanrvlkv 150 d+ +v d+svdv+v+ l l ++n ++ l+e+ rvlk+ tr|Q76I26|Q76I26_MOUSE 129 DMHQV--TDGSVDVVVCTLVLCsVKNQEKILREVCRVLKP 166 55554..7************973689999*********96 PP >> sp|A2APY7|NDUF5_MOUSE Arginine-hydroxylase NDUFAF5, mitochondrial OS=Mus musculus OX=10090 GN=Ndufaf5 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 2.8e-05 0.042 76 154 .. 93 184 .. 39 189 .. 0.70 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 2.8e-05 EEEES-TT-HHHHH--S..-..EEEEESS......-SSTTEEES-T....TS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEE CS Methyltransf_8 76 vadlGcGeakiaeavre..kekvrsfdlv......avnervvacdl....akvPledesvdvavfclslm.gtnladflkeanrvlkv 150 d+GcG ia++ + k+ d++ +++ ++ + ++ +P ++++ d++v lsl +++l l++++ vlk+ sp|A2APY7|NDUF5_MOUSE 93 ALDIGCGRGYIAQHLDKetVGKIFQTDIAehalknSLETDIPTVNIladeEFLPFQENTFDLVVSSLSLHwVNDLPRALEQIHYVLKP 180 579*********65544114567777764221112344454444333211669****************64899************** PP EEEE CS Methyltransf_8 151 GGll 154 G++ sp|A2APY7|NDUF5_MOUSE 181 DGVF 184 9987 PP >> sp|Q9CZB3|THUM2_MOUSE THUMP domain-containing protein 2 OS=Mus musculus OX=10090 GN=Thumpd2 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 0.93 1.4e+03 4 33 .. 32 61 .. 30 83 .. 0.74 2 ? 11.4 0.0 0.00018 0.26 113 155 .. 358 405 .. 341 415 .. 0.81 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.93 XXX-HHHHHHHHHHHHHHHHHS-HHHHHHH CS Methyltransf_8 4 akikkrldgarfrflneklytgesskavdl 33 ++++ rl++++ ++ k++ ++ s + sp|Q9CZB3|THUM2_MOUSE 32 REVRARLEATQVEYISGKVFFTTCSDLPSM 61 67899*************998887765554 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00018 TTS-S--TT-EEEEEEES--.....-SS-HHHHHHHHHHHEEEEEEEE CS Methyltransf_8 113 lakvPledesvdvavfclsl.....mgtnladflkeanrvlkvGGllk 155 ++ +Pl +s dv++ + + +g+++++ l+e++rvl+vGG + sp|Q9CZB3|THUM2_MOUSE 358 VTDLPLPSQSTDVIISDIPFgkkfkLGKDIKSILQEMERVLRVGGAMV 405 677899999999998776543344489******************875 PP >> sp|Q8CAE2|HENMT_MOUSE Small RNA 2'-O-methyltransferase OS=Mus musculus OX=10090 GN=Henmt1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.0 6.5e-05 0.097 62 87 .. 38 63 .. 28 82 .. 0.88 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 6.5e-05 HHHHHHCTS-TTS-EEEES-TT-HHH CS Methyltransf_8 62 viirklkkkkdnlvvadlGcGeakia 87 +++r+l +++ + vadlGcG+ak+ sp|Q8CAE2|HENMT_MOUSE 38 QFVRDLVDRHEPKKVADLGCGDAKLL 63 68999*******************96 PP >> sp|Q8BMK1|METL2_MOUSE Methyltransferase-like protein 2 OS=Mus musculus OX=10090 GN=Mettl2 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.00021 0.32 111 155 .. 234 282 .. 226 299 .. 0.81 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00021 S-T.TS-S--TT-EEEEE..EES---S.S-HHHHHHHHHHHEEEEEEEE CS Methyltransf_8 111 cdl.akvPledesvdvav..fclslmg.tnladflkeanrvlkvGGllk 155 cd + P+ ++s dv+v f ls ++ +++++ + r+lk+GG++ sp|Q8BMK1|METL2_MOUSE 234 CDEdQSYPVPEDSLDVIVliFVLSAIVpDKMQKAISKLSRLLKPGGVML 282 777566789999999865338899776266999*************986 PP >> tr|Q8BGM4|Q8BGM4_MOUSE Methyltransferase-like 27 OS=Mus musculus OX=10090 GN=Mettl27 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00026 0.39 56 156 .. 51 166 .. 38 189 .. 0.76 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00026 SS-HHHHHHHHHCTS-TTS-EEEES-TT-HHH..HH--S-..EEEEE.....SS-.....SSTTEEES-TTS-S--T..T-EEEEEE CS Methyltransf_8 56 PenPldviirklkkkkdnlvvadlGcGeakia..eavrekekvrsfd.....lva.....vnervvacdlakvPled..esvdvavf 128 P +d + r ++ +++ + d+ cG +a + r + +v+ +d l+ + +++ c l + Pl d ++ d +++ tr|Q8BGM4|Q8BGM4_MOUSE 51 PRLAVDCLSRAFRGSPHDALILDVACGTGLVAveLQARGFLQVQGVDgspemLKQarargLYHHLSLCTLGQEPLPDpeGTFDAVII 137 7778999************************9655678899***9994443322112222457889999988777764378998888 PP ES---SS-H.HHHHHHHHHHEEEEEEEEE CS Methyltransf_8 129 clslmgtnl.adflkeanrvlkvGGllkv 156 +l ++ + + e rv k+GGl+ + tr|Q8BGM4|Q8BGM4_MOUSE 138 VGALSEGQVpCSAIPELLRVTKPGGLVCL 166 88877555526899999*******99765 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (219 nodes) Target sequences: 22289 (11757923 residues searched) Passed MSV filter: 509 (0.0228364); expected 445.8 (0.02) Passed bias filter: 371 (0.016645); expected 445.8 (0.02) Passed Vit filter: 39 (0.00174974); expected 22.3 (0.001) Passed Fwd filter: 15 (0.000672978); expected 0.2 (1e-05) Initial search space (Z): 22289 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.18u 0.01s 00:00:00.19 Elapsed: 00:00:00.08 # Mc/sec: 32187.31 // [ok]