# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_8.hmm.txt
# target sequence database: proteomes/Natronomonas_moolapensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_8 [M=219]
Accession: PF05148.15
Description: Hypothetical methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
8e-06 23.2 0.1 2.1e-05 21.8 0.1 1.7 1 tr|M1XL08|M1XL08_NATM8 Probable arsenite(III)-methyltransfer
0.00026 18.2 0.0 0.00039 17.6 0.0 1.2 1 tr|M1XNP7|M1XNP7_NATM8 Probable S-adenosylmethionine-depende
0.002 15.3 0.0 0.0076 13.5 0.0 1.9 2 tr|M1XQI1|M1XQI1_NATM8 Probable S-adenosylmethionine-depende
0.0023 15.1 0.0 0.0095 13.1 0.0 1.8 1 tr|M1XP07|M1XP07_NATM8 Probable S-adenosylmethionine-depende
0.0049 14.1 0.1 0.0074 13.5 0.1 1.2 1 tr|M1XTN7|M1XTN7_NATM8 Probable S-adenosylmethionine-depende
------ inclusion threshold ------
0.038 11.2 0.0 0.088 10.0 0.0 1.6 1 tr|M1Y1P2|M1Y1P2_NATM8 Probable S-adenosylmethionine-depende
Domain annotation for each sequence (and alignments):
>> tr|M1XL08|M1XL08_NATM8 Probable arsenite(III)-methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JCM
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.8 0.1 4.6e-08 2.1e-05 110 159 .. 152 202 .. 88 210 .. 0.87
Alignments for each domain:
== domain 1 score: 21.8 bits; conditional E-value: 4.6e-08
ES-TTS-S--TT-EEEEEE.ES---SS-HHHHHHHHHHHEEEEEEEEEEEE CS
Methyltransf_8 110 acdlakvPledesvdvavf.clslmgtnladflkeanrvlkvGGllkvaev 159
++ ++P+ d+s+dv++ c+ ++ + + ea rvl++GG l +++v
tr|M1XL08|M1XL08_NATM8 152 LGEIEHLPVSDDSIDVIISnCVVNLSPDKPQVFDEAFRVLRPGGRLAISDV 202
457899**********99549999999999******************998 PP
>> tr|M1XNP7|M1XNP7_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.6 0.0 8.7e-07 0.00039 76 157 .. 41 137 .. 28 160 .. 0.72
Alignments for each domain:
== domain 1 score: 17.6 bits; conditional E-value: 8.7e-07
EEEES-TT-HHH.HH--S-..EEEEESS..........-SSTTEEES-TTS-S--TT-EEEEEEES---SS-H....HHHHHHHHHH CS
Methyltransf_8 76 vadlGcGeakia.eavrekekvrsfdlv..........avnervvacdlakvPledesvdvavfclslmgtnl....adflkeanrv 147
d+GcG+ + + ++ ++v +d+ a++ +va d a +P++d++v +av+ +l ++ l e rv
tr|M1XNP7|M1XNP7_NATM8 41 ALDVGCGNGRHTeLLAGHADRVLGLDVShgllsaarerAPGAALVAGDAASLPVADGAVGLAVYVATLHHLPTrrlrRESLDELARV 127
579999999988334567788988885322222222225667799*******************9887654331112578999**** PP
EEEEEEEEEE CS
Methyltransf_8 148 lkvGGllkva 157
l GG+ v+
tr|M1XNP7|M1XNP7_NATM8 128 LDDGGVALVS 137
*****87775 PP
>> tr|M1XQI1|M1XQI1_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 13.5 0.0 1.7e-05 0.0076 76 180 .. 41 150 .. 21 158 .. 0.67
2 ? -0.9 0.0 0.41 1.8e+02 160 183 .. 149 172 .. 134 176 .. 0.85
Alignments for each domain:
== domain 1 score: 13.5 bits; conditional E-value: 1.7e-05
EEEES-TT-HHHHH--S-....EEEEESS-SSTTEEE..S-TTS-S--TT-EEEEEEES---SS.-HHHHHHHHHHHEEEEEEEEEE CS
Methyltransf_8 76 vadlGcGeakiaeavrek..ekvrsfdlvavnervva..cdlakvPledesvdvavfclslmgt.nladflkeanrvlkvGGllkva 157
v d+G G ++a + + + + r + a +++ + +P d+svd +v+ ++ + l e+ rvl +GG+l ++
tr|M1XQI1|M1XQI1_NATM8 41 VLDVGGGSGRVAGETGATvvDPARGMLRRARRRGLESvqASATDLPHPDGSVDAVVVVDAFHHFpAGQRCLSEMARVLAPGGVLVIT 127
566777777777333322002233333334333333300445789********99998888765156899****************9 PP
EEGGG-S-HHHHHHHHHCTTEEE CS
Methyltransf_8 158 evksrfesvklfaraltklGfev 180
+ + + ra +Gf+
tr|M1XQI1|M1XQI1_NATM8 128 DFDRGTRLGWALDRAERLVGFDS 150
98766666666666666667765 PP
== domain 2 score: -0.9 bits; conditional E-value: 0.41
GGG-S-HHHHHHHHHCTTEEEEEE CS
Methyltransf_8 160 ksrfesvklfaraltklGfevksk 183
s f v ++ a+ + Gfevk +
tr|M1XQI1|M1XQI1_NATM8 149 DSTFYTVSELESAIGSAGFEVKPI 172
688899999999999999999865 PP
>> tr|M1XP07|M1XP07_NATM8 Probable S-adenosylmethionine-dependent methyltransferase (Homolog to 24-sterol C-methyltrans
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 13.1 0.0 2.1e-05 0.0095 75 157 .. 41 139 .. 29 148 .. 0.66
Alignments for each domain:
== domain 1 score: 13.1 bits; conditional E-value: 2.1e-05
-EEEES-TT-HHHHH--S...-..EEEEESS-S..........STTE..EES-TTS-S--TT-EEEEEEES--.-SS-HHHHHHHHH CS
Methyltransf_8 75 vvadlGcGeakiaeavre...kekvrsfdlvav..........nerv..vacdlakvPledesvdvavfclsl.mgtnladflkean 145
+v dlGcG a re +v +d ++ ++ v v d+ +P d+svd a ++ + + ++ l e +
tr|M1XP07|M1XP07_NATM8 41 TVLDLGCGSGYAGRALREatdAARVYGLDGAPEmvrnarsytdDPAVgyVLGDFDSLPFVDDSVDHAFSMEAFyYAPDPHSTLCELR 127
6777777765554443331114456666654321111111111222322457999**********99887776257799******** PP
HHEEEEEEEEEE CS
Methyltransf_8 146 rvlkvGGllkva 157
rvl++GG ++ a
tr|M1XP07|M1XP07_NATM8 128 RVLRPGGTFYCA 139
********9987 PP
>> tr|M1XTN7|M1XTN7_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 13.5 0.1 1.6e-05 0.0074 74 134 .. 33 99 .. 24 118 .. 0.73
Alignments for each domain:
== domain 1 score: 13.5 bits; conditional E-value: 1.6e-05
S-EEEES-TT-HHHHH--S-....EEEEE.....SS-SSTTEEES-TTS-S--TT-EEEEEEES---S CS
Methyltransf_8 74 lvvadlGcGeakiaeavrek..ekvrsfd.....lvavnervvacdlakvPledesvdvavfclslmg 134
v+d+GcGe ++ re+ +v d l+ ++ v d ++P +d+svd++ c +l+
tr|M1XTN7|M1XTN7_NATM8 33 ERVVDVGCGEGALTRVLREEcpGEVVGCDrdarlLAELEGPTVRGDAYRLPFADGSVDLV-ACQALLI 99
5699*********9777765225788777556656778899999**************86.4555543 PP
>> tr|M1Y1P2|M1Y1P2_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.0 0.0 0.00019 0.088 75 157 .. 39 134 .. 28 141 .. 0.69
Alignments for each domain:
== domain 1 score: 10.0 bits; conditional E-value: 0.00019
-EEEES-TT-HHH.HH--S-..EEEEESS-S............STTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHE CS
Methyltransf_8 75 vvadlGcGeakia.eavrekekvrsfdlvav............nervvacdlakvPledesvdvavfclslmgtnladflkeanrvl 148
++adlG G + r+ v+++d++a n + v+ + +P ed++ d a ++ + + e+ rvl
tr|M1Y1P2|M1Y1P2_NATM8 39 TIADLGSGTGFYTdLVARHAGTVHAVDVQAAmheryvekglpdNVQTVTAPIDGLPFEDGALDAAFTTMTYHEFSGPEAIGEIARVL 125
5777777776665233445556777776553111111111111223345667899************9999999999********** PP
EEEEEEEEE CS
Methyltransf_8 149 kvGGllkva 157
+GG + v
tr|M1Y1P2|M1Y1P2_NATM8 126 APGGRVVVV 134
****99886 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (219 nodes)
Target sequences: 2723 (809592 residues searched)
Passed MSV filter: 48 (0.0176276); expected 54.5 (0.02)
Passed bias filter: 47 (0.0172604); expected 54.5 (0.02)
Passed Vit filter: 11 (0.00403966); expected 2.7 (0.001)
Passed Fwd filter: 6 (0.00220345); expected 0.0 (1e-05)
Initial search space (Z): 2723 [actual number of targets]
Domain search space (domZ): 6 [number of targets reported over threshold]
# CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.01
# Mc/sec: 17730.06
//
[ok]