# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_8.hmm.txt # target sequence database: proteomes/Natronomonas_moolapensis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_8 [M=219] Accession: PF05148.15 Description: Hypothetical methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8e-06 23.2 0.1 2.1e-05 21.8 0.1 1.7 1 tr|M1XL08|M1XL08_NATM8 Probable arsenite(III)-methyltransfer 0.00026 18.2 0.0 0.00039 17.6 0.0 1.2 1 tr|M1XNP7|M1XNP7_NATM8 Probable S-adenosylmethionine-depende 0.002 15.3 0.0 0.0076 13.5 0.0 1.9 2 tr|M1XQI1|M1XQI1_NATM8 Probable S-adenosylmethionine-depende 0.0023 15.1 0.0 0.0095 13.1 0.0 1.8 1 tr|M1XP07|M1XP07_NATM8 Probable S-adenosylmethionine-depende 0.0049 14.1 0.1 0.0074 13.5 0.1 1.2 1 tr|M1XTN7|M1XTN7_NATM8 Probable S-adenosylmethionine-depende ------ inclusion threshold ------ 0.038 11.2 0.0 0.088 10.0 0.0 1.6 1 tr|M1Y1P2|M1Y1P2_NATM8 Probable S-adenosylmethionine-depende Domain annotation for each sequence (and alignments): >> tr|M1XL08|M1XL08_NATM8 Probable arsenite(III)-methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JCM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.1 4.6e-08 2.1e-05 110 159 .. 152 202 .. 88 210 .. 0.87 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 4.6e-08 ES-TTS-S--TT-EEEEEE.ES---SS-HHHHHHHHHHHEEEEEEEEEEEE CS Methyltransf_8 110 acdlakvPledesvdvavf.clslmgtnladflkeanrvlkvGGllkvaev 159 ++ ++P+ d+s+dv++ c+ ++ + + ea rvl++GG l +++v tr|M1XL08|M1XL08_NATM8 152 LGEIEHLPVSDDSIDVIISnCVVNLSPDKPQVFDEAFRVLRPGGRLAISDV 202 457899**********99549999999999******************998 PP >> tr|M1XNP7|M1XNP7_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.0 8.7e-07 0.00039 76 157 .. 41 137 .. 28 160 .. 0.72 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 8.7e-07 EEEES-TT-HHH.HH--S-..EEEEESS..........-SSTTEEES-TTS-S--TT-EEEEEEES---SS-H....HHHHHHHHHH CS Methyltransf_8 76 vadlGcGeakia.eavrekekvrsfdlv..........avnervvacdlakvPledesvdvavfclslmgtnl....adflkeanrv 147 d+GcG+ + + ++ ++v +d+ a++ +va d a +P++d++v +av+ +l ++ l e rv tr|M1XNP7|M1XNP7_NATM8 41 ALDVGCGNGRHTeLLAGHADRVLGLDVShgllsaarerAPGAALVAGDAASLPVADGAVGLAVYVATLHHLPTrrlrRESLDELARV 127 579999999988334567788988885322222222225667799*******************9887654331112578999**** PP EEEEEEEEEE CS Methyltransf_8 148 lkvGGllkva 157 l GG+ v+ tr|M1XNP7|M1XNP7_NATM8 128 LDDGGVALVS 137 *****87775 PP >> tr|M1XQI1|M1XQI1_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.0 1.7e-05 0.0076 76 180 .. 41 150 .. 21 158 .. 0.67 2 ? -0.9 0.0 0.41 1.8e+02 160 183 .. 149 172 .. 134 176 .. 0.85 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.7e-05 EEEES-TT-HHHHH--S-....EEEEESS-SSTTEEE..S-TTS-S--TT-EEEEEEES---SS.-HHHHHHHHHHHEEEEEEEEEE CS Methyltransf_8 76 vadlGcGeakiaeavrek..ekvrsfdlvavnervva..cdlakvPledesvdvavfclslmgt.nladflkeanrvlkvGGllkva 157 v d+G G ++a + + + + r + a +++ + +P d+svd +v+ ++ + l e+ rvl +GG+l ++ tr|M1XQI1|M1XQI1_NATM8 41 VLDVGGGSGRVAGETGATvvDPARGMLRRARRRGLESvqASATDLPHPDGSVDAVVVVDAFHHFpAGQRCLSEMARVLAPGGVLVIT 127 566777777777333322002233333334333333300445789********99998888765156899****************9 PP EEGGG-S-HHHHHHHHHCTTEEE CS Methyltransf_8 158 evksrfesvklfaraltklGfev 180 + + + ra +Gf+ tr|M1XQI1|M1XQI1_NATM8 128 DFDRGTRLGWALDRAERLVGFDS 150 98766666666666666667765 PP == domain 2 score: -0.9 bits; conditional E-value: 0.41 GGG-S-HHHHHHHHHCTTEEEEEE CS Methyltransf_8 160 ksrfesvklfaraltklGfevksk 183 s f v ++ a+ + Gfevk + tr|M1XQI1|M1XQI1_NATM8 149 DSTFYTVSELESAIGSAGFEVKPI 172 688899999999999999999865 PP >> tr|M1XP07|M1XP07_NATM8 Probable S-adenosylmethionine-dependent methyltransferase (Homolog to 24-sterol C-methyltrans # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.0 2.1e-05 0.0095 75 157 .. 41 139 .. 29 148 .. 0.66 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 2.1e-05 -EEEES-TT-HHHHH--S...-..EEEEESS-S..........STTE..EES-TTS-S--TT-EEEEEEES--.-SS-HHHHHHHHH CS Methyltransf_8 75 vvadlGcGeakiaeavre...kekvrsfdlvav..........nerv..vacdlakvPledesvdvavfclsl.mgtnladflkean 145 +v dlGcG a re +v +d ++ ++ v v d+ +P d+svd a ++ + + ++ l e + tr|M1XP07|M1XP07_NATM8 41 TVLDLGCGSGYAGRALREatdAARVYGLDGAPEmvrnarsytdDPAVgyVLGDFDSLPFVDDSVDHAFSMEAFyYAPDPHSTLCELR 127 6777777765554443331114456666654321111111111222322457999**********99887776257799******** PP HHEEEEEEEEEE CS Methyltransf_8 146 rvlkvGGllkva 157 rvl++GG ++ a tr|M1XP07|M1XP07_NATM8 128 RVLRPGGTFYCA 139 ********9987 PP >> tr|M1XTN7|M1XTN7_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.5 0.1 1.6e-05 0.0074 74 134 .. 33 99 .. 24 118 .. 0.73 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 1.6e-05 S-EEEES-TT-HHHHH--S-....EEEEE.....SS-SSTTEEES-TTS-S--TT-EEEEEEES---S CS Methyltransf_8 74 lvvadlGcGeakiaeavrek..ekvrsfd.....lvavnervvacdlakvPledesvdvavfclslmg 134 v+d+GcGe ++ re+ +v d l+ ++ v d ++P +d+svd++ c +l+ tr|M1XTN7|M1XTN7_NATM8 33 ERVVDVGCGEGALTRVLREEcpGEVVGCDrdarlLAELEGPTVRGDAYRLPFADGSVDLV-ACQALLI 99 5699*********9777765225788777556656778899999**************86.4555543 PP >> tr|M1Y1P2|M1Y1P2_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.0 0.00019 0.088 75 157 .. 39 134 .. 28 141 .. 0.69 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00019 -EEEES-TT-HHH.HH--S-..EEEEESS-S............STTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHE CS Methyltransf_8 75 vvadlGcGeakia.eavrekekvrsfdlvav............nervvacdlakvPledesvdvavfclslmgtnladflkeanrvl 148 ++adlG G + r+ v+++d++a n + v+ + +P ed++ d a ++ + + e+ rvl tr|M1Y1P2|M1Y1P2_NATM8 39 TIADLGSGTGFYTdLVARHAGTVHAVDVQAAmheryvekglpdNVQTVTAPIDGLPFEDGALDAAFTTMTYHEFSGPEAIGEIARVL 125 5777777776665233445556777776553111111111111223345667899************9999999999********** PP EEEEEEEEE CS Methyltransf_8 149 kvGGllkva 157 +GG + v tr|M1Y1P2|M1Y1P2_NATM8 126 APGGRVVVV 134 ****99886 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (219 nodes) Target sequences: 2723 (809592 residues searched) Passed MSV filter: 48 (0.0176276); expected 54.5 (0.02) Passed bias filter: 47 (0.0172604); expected 54.5 (0.02) Passed Vit filter: 11 (0.00403966); expected 2.7 (0.001) Passed Fwd filter: 6 (0.00220345); expected 0.0 (1e-05) Initial search space (Z): 2723 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.01 # Mc/sec: 17730.06 // [ok]