# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_8.hmm.txt
# target sequence database: proteomes/Saccharomyces_cerevisiae.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_8 [M=219]
Accession: PF05148.15
Description: Hypothetical methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.1e-68 229.9 2.4 3.2e-66 221.8 0.1 2.9 2 sp|P38961|RRP8_YEAST 25S rRNA (adenine(645)-N(1))-methyltran
0.0019 16.5 0.0 0.088 11.1 0.0 2.4 2 sp|P49017|COQ5_YEAST 2-methoxy-6-polyprenyl-1,4-benzoquinol
Domain annotation for each sequence (and alignments):
>> sp|P38961|RRP8_YEAST 25S rRNA (adenine(645)-N(1))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 221.8 0.1 1.1e-69 3.2e-66 2 200 .. 113 344 .. 112 357 .. 0.91
2 ! 6.3 0.6 0.00088 2.6 185 219 .] 355 392 .] 345 392 .] 0.74
Alignments for each domain:
== domain 1 score: 221.8 bits; conditional E-value: 1.1e-69
XXXXX-HHHHHHHHHHHHHHHHHS-HHHHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHC................TS-TTS CS
Methyltransf_8 2 leakikkrldgarfrflneklytgesskavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklk................kkkdnl 74
l++k+ +l g+rfr++ne+lyt +s++a +l+ke+p++fd yh+gfrsqv+ WPenP+dv++ +++ k +++
sp|P38961|RRP8_YEAST 113 LQQKMMAKLTGSRFRWINEQLYTISSDEALKLIKEQPQLFDEYHDGFRSQVQAWPENPVDVFVDQIRyrcmkpvnapgglpglKDSKEI 201
79********************************************************************************99999** PP
-EEEES-TT-HHH...............HH--S-..EEEEESS-SSTTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHE CS
Methyltransf_8 75 vvadlGcGeakia...............eavrekekvrsfdlvavnervvacdlakvPledesvdvavfclslmgtnladflkeanrvl 148
v+ad+GcGea++a + ++ +kv+sfdl+ ner+++ d+++vPl des ++vfcl+lmgtn+ df+kea+r+l
sp|P38961|RRP8_YEAST 202 VIADMGCGEAQLAleinnffknynkkakKYLKRRHKVHSFDLKKANERITVADIRNVPLPDESCTIVVFCLALMGTNFLDFIKEAYRIL 290
*************87777665554332222356799***************************************************** PP
EEEEEEEEEEEGGG-S..-HHHHHHHHHCTTEEEEEEE--STTEEEEEEEE-SS CS
Methyltransf_8 149 kvGGllkvaevksrfe..svklfaraltklGfevkskdlsnkqfvlfefkkvek 200
+ G l++ae+ksrf+ +++ f+ al+ +Gf k++ +nk+f+ fef k +
sp|P38961|RRP8_YEAST 291 APRGELWIAEIKSRFSdgKGNEFVDALKLMGFFHKKTFDENKMFTRFEFFKPPA 344
****************444679***************************99763 PP
== domain 2 score: 6.3 bits; conditional E-value: 0.00088
--STTEEEEEEEE-SSS-TT---...GG--------XX CS
Methyltransf_8 185 lsnkqfvlfefkkvekkgkkrel...glklkpclykkr 219
+ ++f+ +e +k e ++k+r++ + lkpc+yk+r
sp|P38961|RRP8_YEAST 355 ERRQKFIEVETEKEELEKKRRKIaegKWLLKPCIYKRR 392
45678999999999866666655434788********9 PP
>> sp|P49017|COQ5_YEAST 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Saccharomyces cerevisiae (st
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 11.1 0.0 2.9e-05 0.088 122 160 .. 190 229 .. 182 257 .. 0.75
2 ! 2.8 0.0 0.0099 30 155 181 .. 263 289 .. 258 297 .. 0.84
Alignments for each domain:
== domain 1 score: 11.1 bits; conditional E-value: 2.9e-05
-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEEEG CS
Methyltransf_8 122 svdvavfclslm.gtnladflkeanrvlkvGGllkvaevk 160
s d+ + + + t++++ l+ a+rvlk+GG+++ e +
sp|P49017|COQ5_YEAST 190 SKDIYTVSFGIRnFTDIQKGLNTAYRVLKPGGIFYCLEFS 229
55555555544314899999**************998864 PP
== domain 2 score: 2.8 bits; conditional E-value: 0.0099
EEEEEGGG-S-HHHHHHHHHCTTEEEE CS
Methyltransf_8 155 kvaevksrfesvklfaraltklGfevk 181
++ e rf++ ++f+ ++k Gf+
sp|P49017|COQ5_YEAST 263 YLVESIERFPDQETFKSMIEKAGFKSA 289
5667778*****************976 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (219 nodes)
Target sequences: 6049 (2936363 residues searched)
Passed MSV filter: 169 (0.0279385); expected 121.0 (0.02)
Passed bias filter: 116 (0.0191767); expected 121.0 (0.02)
Passed Vit filter: 9 (0.00148785); expected 6.0 (0.001)
Passed Fwd filter: 2 (0.000330633); expected 0.1 (1e-05)
Initial search space (Z): 6049 [actual number of targets]
Domain search space (domZ): 2 [number of targets reported over threshold]
# CPU time: 0.07u 0.00s 00:00:00.07 Elapsed: 00:00:00.03
# Mc/sec: 21435.45
//
[ok]