# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_8.hmm.txt
# target sequence database: proteomes/Tetrahymena_thermophila.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_8 [M=219]
Accession: PF05148.15
Description: Hypothetical methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
5.4e-60 203.5 8.9 1e-57 196.1 4.7 3.2 2 tr|W7X772|W7X772_TETTS Methyltransferase, putative OS=Tetrah
3e-05 24.6 0.1 0.03 14.7 0.0 3.1 3 tr|W7X2L6|W7X2L6_TETTS 2-methoxy-6-polyprenyl-1,4-benzoquino
0.0019 18.7 0.0 0.0034 17.9 0.0 1.5 1 tr|Q23VZ1|Q23VZ1_TETTS UbiE/COQ5 methyltransferase OS=Tetrah
0.0063 17.0 0.0 0.017 15.6 0.0 1.7 1 tr|Q24E30|Q24E30_TETTS UbiE/COQ5 methyltransferase OS=Tetrah
------ inclusion threshold ------
0.016 15.6 0.0 0.026 15.0 0.0 1.3 1 tr|Q23PZ6|Q23PZ6_TETTS Cyclopropane-fatty-acyl-phospholipid
0.029 14.8 0.0 0.045 14.2 0.0 1.4 1 tr|Q22D66|Q22D66_TETTS UbiE/COQ5 methyltransferase OS=Tetrah
0.037 14.4 0.0 0.076 13.4 0.0 1.5 1 tr|Q23BQ2|Q23BQ2_TETTS Adenylate kinase family protein OS=Te
0.089 13.2 0.0 0.17 12.3 0.0 1.5 1 tr|Q24E29|Q24E29_TETTS UbiE/COQ5 family methyltransferase OS
0.09 13.2 0.0 0.26 11.7 0.0 1.6 2 tr|W7XIC4|W7XIC4_TETTS UbiE/COQ5 methyltransferase OS=Tetrah
0.13 12.6 0.0 0.23 11.8 0.0 1.3 1 tr|W7X0Z1|W7X0Z1_TETTS UbiE/COQ5 methyltransferase, putative
Domain annotation for each sequence (and alignments):
>> tr|W7X772|W7X772_TETTS Methyltransferase, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_000
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 196.1 4.7 3.9e-61 1e-57 1 206 [. 112 333 .. 112 346 .. 0.89
2 ? 4.0 0.5 0.021 57 191 219 .] 347 376 .] 328 376 .] 0.61
Alignments for each domain:
== domain 1 score: 196.1 bits; conditional E-value: 3.9e-61
XXXXXX-HHHHHHHHHHHHHHHHHS-HHHHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHCTS-..TTS-EEEES-TT-H CS
Methyltransf_8 1 dleakikkrldgarfrflneklytgesskavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklkkkk..dnlvvadlGcGeak 85
dl+++i++ l g++fr++ne lyt++s+ d f ++ e f lyh+gf+sq+ kWPe+P+d+ii++l++ + +n v+adlGcG+ k
tr|W7X772|W7X772_TETTS 112 DLTNRIEQGLVGSKFRMINEYLYTTDSKTSADHFAKNKEDFLLYHQGFQSQIVKWPEKPVDMIINELNSNQifQNAVIADLGCGDGK 198
68899**************************************************************96654489************ PP
HH..............HH--S-..EEEEESS-SSTTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEEEEEEEE CS
Methyltransf_8 86 ia..............eavrekekvrsfdlvavnervvacdlakvPledesvdvavfclslmgtnladflkeanrvlkvGGllkvae 158
i + ++ +++v+sfdl a ++ + + d +++Pl+++ dv+vfcl+lmgtn+ +fl eanr+lk G+l ++e
tr|W7X772|W7X772_TETTS 199 IFeyfrdnnklksldsSVKQGMKEVHSFDLCAHKDFIKVADSKNIPLKNSECDVVVFCLALMGTNYIEFLTEANRLLKLNGHLIISE 285
*86655544444333222344578*************************************************************** PP
EGGG-S-HHHHHHHHHCTTEEEEEEE--STTEEEEEEEE-SSS-TT-- CS
Methyltransf_8 159 vksrfesvklfaraltklGfevkskdlsnkqfvlfefkkvekkgkkre 206
v+sr+++++lf+ ++ lGf+ ++k l n++f ++ fkk ++ k +
tr|W7X772|W7X772_TETTS 286 VNSRITDMDLFIGMIECLGFKLQKKILPNTYFCFLTFKKLADNKLKLN 333
***************************************986655544 PP
== domain 2 score: 4.0 bits; conditional E-value: 0.021
EEEEEEE-SSS-TT---.GG--------XX CS
Methyltransf_8 191 vlfefkkvekkgkkrel.glklkpclykkr 219
+ +f k++ +++ + + lkpc+ykkr
tr|W7X772|W7X772_TETTS 347 YIAKFPKTKDQSDVLYIsQSLLKPCIYKKR 376
3455666665555544446789*******9 PP
>> tr|W7X2L6|W7X2L6_TETTS 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Tetrahymena thermophila (s
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 4.1 0.1 0.021 55 71 115 .. 101 144 .. 23 151 .. 0.70
2 ! 14.7 0.0 1.1e-05 0.03 110 160 .. 167 219 .. 151 234 .. 0.79
3 ? 2.0 0.0 0.087 2.3e+02 154 184 .. 253 283 .. 244 289 .. 0.87
Alignments for each domain:
== domain 1 score: 4.1 bits; conditional E-value: 0.021
-TTS-EEEES-TT-HHHHH--S-..EEEEESS-SSTTEEES-TTS CS
Methyltransf_8 71 kdnlvvadlGcGeakiaeavrekekvrsfdlvavnervvacdlak 115
++ v d+ G ia+++ +k+k rs l + n +v++ d+++
tr|W7X2L6|W7X2L6_TETTS 101 EQPARVLDVAGGTGDIAFRILDKHKSRS-SLNSKNLKVTVLDINE 144
3445689****************99998.6999999999999965 PP
== domain 2 score: 14.7 bits; conditional E-value: 1.1e-05
ES-T.TS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEEEG CS
Methyltransf_8 110 acdl.akvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkvaevk 160
+c +P ed++ d + + + +++ l ea+rvlk+GG l++ e +
tr|W7X2L6|W7X2L6_TETTS 167 VCGNaEILPFEDNTFDAYTIAYGIRnVPRIEKALSEAHRVLKKGGRLMILEFS 219
56552457********98888887526789*******************9964 PP
== domain 3 score: 2.0 bits; conditional E-value: 0.087
EEEEEEGGG-S-HHHHHHHHHCTTEEEEEEE CS
Methyltransf_8 154 lkvaevksrfesvklfaraltklGfevkskd 184
++ae +f++ ++++r +++ Gf+ s +
tr|W7X2L6|W7X2L6_TETTS 253 QYLAESIDKFHDQQTLLRLIEEAGFKFASYK 283
58999999*****************998765 PP
>> tr|Q23VZ1|Q23VZ1_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_007
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.9 0.0 1.3e-06 0.0034 113 154 .. 120 162 .. 109 211 .. 0.82
Alignments for each domain:
== domain 1 score: 17.9 bits; conditional E-value: 1.3e-06
TTS-S--TT-EEEEEEES--.-SS-HHHHHHHHHHHEEEEEEE CS
Methyltransf_8 113 lakvPledesvdvavfclsl.mgtnladflkeanrvlkvGGll 154
++P +de+ d ++ l l ++tn ++l ea rvl++GG+
tr|Q23VZ1|Q23VZ1_TETTS 120 GEQLPFKDETFDCYICNLCLqITTNPDKMLSEAIRVLQKGGYA 162
579*************999845789999*************74 PP
>> tr|Q24E30|Q24E30_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_008
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.6 0.0 6.3e-06 0.017 108 153 .. 106 152 .. 97 159 .. 0.80
Alignments for each domain:
== domain 1 score: 15.6 bits; conditional E-value: 6.3e-06
EEES-TTS-S--TT-EEEEEEES--.-SS-HHHHHHHHHHHEEEEEE CS
Methyltransf_8 108 vvacdlakvPledesvdvavfclsl.mgtnladflkeanrvlkvGGl 153
++ + ++P ed++ d + l l ++t+ ++lke +rvl++GG+
tr|Q24E30|Q24E30_TETTS 106 IQKANGEELPFEDNTFDCYIANLCLqITTDPVKMLKESHRVLQKGGV 152
555566789********7776666534688999*************7 PP
>> tr|Q23PZ6|Q23PZ6_TETTS Cyclopropane-fatty-acyl-phospholipid synthase OS=Tetrahymena thermophila (strain SB210) OX=31
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 15.0 0.0 9.5e-06 0.026 114 185 .. 211 283 .. 197 312 .. 0.75
Alignments for each domain:
== domain 1 score: 15.0 bits; conditional E-value: 9.5e-06
TS-S.--TT-EEEEEEES-.--SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S-HHHHHHHHHCTTEEEEEEE- CS
Methyltransf_8 114 akvP.ledesvdvavfcls.lmgtnladflkeanrvlkvGGllkvaevksrfesvklfaraltklGfevkskdl 185
++P ++++s dva+ s n+ +f++++nr lk+GG++ ++ ++ +e +++ +++l + ++ k +
tr|Q23PZ6|Q23PZ6_TETTS 211 DQIPeIQENSFDVAINVESsHCYGNFDQFIQQINRALKPGGFFCFTDFRTELE-CQQLDTYFKSLPYFQVIKSE 283
5677568899*****987615678*********************99999886.45566666666555444444 PP
>> tr|Q22D66|Q22D66_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_009
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.2 0.0 1.7e-05 0.045 107 153 .. 105 152 .. 84 205 .. 0.82
Alignments for each domain:
== domain 1 score: 14.2 bits; conditional E-value: 1.7e-05
TEEES-TTS-S--TT-EEEEEEES---SS-.HHHHHHHHHHHEEEEEE CS
Methyltransf_8 107 rvvacdlakvPledesvdvavfclslmgtn.ladflkeanrvlkvGGl 153
++ + ++P d++ d + l l tn a++lke +rvl++GG+
tr|Q22D66|Q22D66_TETTS 105 TIEKANGEELPFLDGTFDCYIANLCLQITNdPAKMLKESYRVLQKGGV 152
5566666789********9888888766542789*************7 PP
>> tr|Q23BQ2|Q23BQ2_TETTS Adenylate kinase family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.4 0.0 2.8e-05 0.076 29 99 .. 11 83 .. 2 96 .. 0.75
Alignments for each domain:
== domain 1 score: 13.4 bits; conditional E-value: 2.8e-05
HHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHC..TS-TTS-EEEES-TT-HHHHH--S-..EEEE CS
Methyltransf_8 29 kavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklk..kkkdnlvvadlGcGeakiaeavrekekvrsf 99
+ v+ + e+ +++d++ ++ ++ v P +Pld +i+kl ++k vv G + +a + ++ k ++
tr|Q23BQ2|Q23BQ2_TETTS 11 RDVEQYLEKNKVYDIFENLMKDLVIDQPAQPLDYLIKKLSepQQKRVFVVGPPGSKTTELALQLANEFKFTCI 83
5667778999*****************************8444444455555666666677666666666555 PP
>> tr|Q24E29|Q24E29_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.3 0.0 6.2e-05 0.17 103 153 .. 101 152 .. 57 157 .. 0.75
Alignments for each domain:
== domain 1 score: 12.3 bits; conditional E-value: 6.2e-05
-SSTTEEES-TTS-S--TT-EEEEEEES---SS.-HHHHHHHHHHHEEEEEE CS
Methyltransf_8 103 avnervvacdlakvPledesvdvavfclslmgt.nladflkeanrvlkvGGl 153
n ++ + ++P e es d + l l t + ++l e +rvl++GG+
tr|Q24E29|Q24E29_TETTS 101 KYNLTIQKANAEQLPFEQESFDCLIGNLCLHITpDPVKMLSESYRVLQKGGV 152
455667788889**********99977777554377889************7 PP
>> tr|W7XIC4|W7XIC4_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_000
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.7 0.0 9.6e-05 0.26 116 153 .. 139 177 .. 121 210 .. 0.76
2 ? -2.1 0.0 1.6 4.2e+03 154 179 .. 205 232 .. 184 239 .. 0.78
Alignments for each domain:
== domain 1 score: 11.7 bits; conditional E-value: 9.6e-05
-S--TT-EEEEEEES--.-SS-HHHHHHHHHHHEEEEEE CS
Methyltransf_8 116 vPledesvdvavfclsl.mgtnladflkeanrvlkvGGl 153
+ ++e d + l l ++tn +++++eanrvl++GG+
tr|W7XIC4|W7XIC4_TETTS 139 LHYKNEMFDCYIANLCLqITTNPEKMIQEANRVLQPGGY 177
55566666655544444257999***************7 PP
== domain 2 score: -2.1 bits; conditional E-value: 1.6
EEEEEEGGG-S..-HHHHHHHHHCTTEE CS
Methyltransf_8 154 lkvaevksrfe..svklfaraltklGfe 179
+k+ v+s f+ + +++++ l+++Gf
tr|W7XIC4|W7XIC4_TETTS 205 IKLPKVRSNFHlnDKQKLINMLEQFGFT 232
5777889988777888999999999996 PP
>> tr|W7X0Z1|W7X0Z1_TETTS UbiE/COQ5 methyltransferase, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.8 0.0 8.6e-05 0.23 114 154 .. 111 152 .. 98 168 .. 0.82
Alignments for each domain:
== domain 1 score: 11.8 bits; conditional E-value: 8.6e-05
TS-S--TT-EEEEEEES--.-SS-HHHHHHHHHHHEEEEEEE CS
Methyltransf_8 114 akvPledesvdvavfclsl.mgtnladflkeanrvlkvGGll 154
+P d++ d + l l ++ + +++l+e +rvl++GG++
tr|W7X0Z1|W7X0Z1_TETTS 111 ETLPYSDGTFDCYIANLCLqLTPDPQKMLNESYRVLQKGGVV 152
579********776655552345899**************85 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (219 nodes)
Target sequences: 26971 (16912921 residues searched)
Passed MSV filter: 1606 (0.0595454); expected 539.4 (0.02)
Passed bias filter: 298 (0.0110489); expected 539.4 (0.02)
Passed Vit filter: 34 (0.00126061); expected 27.0 (0.001)
Passed Fwd filter: 10 (0.000370769); expected 0.3 (1e-05)
Initial search space (Z): 26971 [actual number of targets]
Domain search space (domZ): 10 [number of targets reported over threshold]
# CPU time: 0.26u 0.01s 00:00:00.27 Elapsed: 00:00:00.10
# Mc/sec: 37039.30
//
[ok]