# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_8.hmm.txt
# target sequence database: proteomes/Thermococcus_kodakarensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_8 [M=219]
Accession: PF05148.15
Description: Hypothetical methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
3.2e-07 27.5 0.0 1.7e-06 25.2 0.0 1.9 1 tr|Q5JFQ4|Q5JFQ4_THEKO SAM-dependent methyltransferase, UbiE
2.1e-06 24.8 0.0 1.1e-05 22.4 0.0 1.9 2 tr|Q5JG60|Q5JG60_THEKO SAM-dependent methyltransferase, UbiE
5.5e-05 20.2 0.0 0.0004 17.4 0.0 2.1 2 tr|Q5JHQ2|Q5JHQ2_THEKO SAM-dependent methyltransferase, UbiE
Domain annotation for each sequence (and alignments):
>> tr|Q5JFQ4|Q5JFQ4_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 25.2 0.0 2.2e-09 1.7e-06 41 160 .. 7 138 .. 1 151 [. 0.70
Alignments for each domain:
== domain 1 score: 25.2 bits; conditional E-value: 2.2e-09
HHHHHHHHHHHHC..TSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHH..HH--S-..EEEEE.S.S-SSTT..EEES-..TTS-S CS
Methyltransf_8 41 fdlyhkgfrsqvk..kWPenPldviirklkkkkdnlvvadlGcGeakia..eavrekekvrsfd.l.vavner..vvacd..lakvP 117
fd + + +++ v+ +W + ++++r + ++ ++ vv+d+GcG i + ++ v+ + + +a e+ ++ d + ++P
tr|Q5JFQ4|Q5JFQ4_THEKO 7 FDSWAESYDEDVMsdGWIHSDYERVLRLVAER-AKGVVVDVGCGTGNILrfLRCERYIGVEPSEgMrKAFREKwgFEPIDghFLEIP 92
67777888888864469999999999887766.678999*********943333444444433312123333322455552269*** PP
--TT-EEEEEEES---...SS-HHHHHHHHHHHEEEEEEEEEEEEG CS
Methyltransf_8 118 ledesvdvavfclslm...gtnladflkeanrvlkvGGllkvaevk 160
l ++s+d +v ++ ++ + ++e+ rvl++GG+l +a+v
tr|Q5JFQ4|Q5JFQ4_THEKO 93 LPEGSADTVVSTYAFHhvpDEEKGEAIREMLRVLRPGGILIIADVM 138
*******9998877642124677899******************96 PP
>> tr|Q5JG60|Q5JG60_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.4 0.0 1.5e-08 1.1e-05 105 169 .. 76 141 .. 11 173 .. 0.68
2 ? 1.3 0.1 0.043 33 161 186 .. 154 178 .. 147 197 .. 0.72
Alignments for each domain:
== domain 1 score: 22.4 bits; conditional E-value: 1.5e-08
STTEEES-TTS-S--TT-EEEEEEES--.-SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S-HHHH CS
Methyltransf_8 105 nervvacdlakvPledesvdvavfclsl.mgtnladflkeanrvlkvGGllkvaevksrfesvklf 169
+ +v+ ++P e++s+d ++ ++ +++ ++ lkea+rvlk+GG l + v + ++ +
tr|Q5JG60|Q5JG60_THEKO 76 GIEVIEGTAENLPFEEDSMDYLLMVTTIcFVDDPEKALKEAYRVLKPGGALIIGFVDRNSPIGRFY 141
4467777789**********88777665268999*****************999886444333333 PP
== domain 2 score: 1.3 bits; conditional E-value: 0.043
GG-S-HHHHHHHHHCTTEEEEEEE-- CS
Methyltransf_8 161 srfesvklfaraltklGfevkskdls 186
+rf s + +++ l+k+Gf ++ ++
tr|Q5JG60|Q5JG60_THEKO 154 ARFFSTEELLELLKKVGFREFEI-VQ 178
799***************76443.33 PP
>> tr|Q5JHQ2|Q5JHQ2_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -0.1 0.0 0.12 88 169 197 .. 52 78 .. 33 89 .. 0.70
2 ! 17.4 0.0 5.2e-07 0.0004 109 155 .. 90 139 .. 81 148 .. 0.85
Alignments for each domain:
== domain 1 score: -0.1 bits; conditional E-value: 0.12
HHHHHHCTTEEEEEEE--STTEEEEEEEE CS
Methyltransf_8 169 faraltklGfevkskdlsnkqfvlfefkk 197
f l+ lGfev+ l n+ f+l + +
tr|Q5JHQ2|Q5JHQ2_THEKO 52 FSFLLEDLGFEVVG--LDNSRFMLEKARE 78
55567889999865..5677888765544 PP
== domain 2 score: 17.4 bits; conditional E-value: 5.2e-07
EES-TTS-S--TT-EEEEEEES---S...S-HHHHHHHHHHHEEEEEEEE CS
Methyltransf_8 109 vacdlakvPledesvdvavfclslmg...tnladflkeanrvlkvGGllk 155
+ d +++P e++s d ++f sl+ ++la+ ke rvlk+GG +
tr|Q5JHQ2|Q5JHQ2_THEKO 90 IEGDARELPFENDSFDYVLFIDSLVHfepQDLAKVFKETARVLKPGGKFI 139
567999*****************9963337899999***********875 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (219 nodes)
Target sequences: 2301 (637680 residues searched)
Passed MSV filter: 93 (0.0404172); expected 46.0 (0.02)
Passed bias filter: 77 (0.0334637); expected 46.0 (0.02)
Passed Vit filter: 6 (0.00260756); expected 2.3 (0.001)
Passed Fwd filter: 3 (0.00130378); expected 0.0 (1e-05)
Initial search space (Z): 2301 [actual number of targets]
Domain search space (domZ): 3 [number of targets reported over threshold]
# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01
# Mc/sec: 13965.19
//
[ok]