# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Methyltransf_8.hmm.txt # target sequence database: proteomes/Trichomonas_vaginalis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Methyltransf_8 [M=219] Accession: PF05148.15 Description: Hypothetical methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-73 248.6 0.1 2.1e-73 248.2 0.1 1.0 1 tr|A2F0C3|A2F0C3_TRIVA Uncharacterized protein OS=Trichomona 0.00058 21.2 0.1 0.002 19.5 0.1 1.7 2 tr|A2FK19|A2FK19_TRIVA Methyltransferase, putative OS=Tricho 0.0011 20.3 0.0 0.0014 20.0 0.0 1.3 1 tr|A2FH79|A2FH79_TRIVA Uncharacterized protein OS=Trichomona 0.0024 19.2 0.0 0.0045 18.3 0.0 1.3 1 tr|A2GIP8|A2GIP8_TRIVA Uncharacterized protein OS=Trichomona ------ inclusion threshold ------ 0.015 16.6 0.0 0.022 16.1 0.0 1.4 1 tr|A2DVE6|A2DVE6_TRIVA Methyltransferase, putative OS=Tricho 0.036 15.4 0.0 0.12 13.6 0.0 1.8 1 tr|A2EDP7|A2EDP7_TRIVA Uncharacterized protein OS=Trichomona 0.039 15.3 0.1 0.067 14.5 0.1 1.4 1 tr|A2DMU5|A2DMU5_TRIVA Methyltransferase, putative OS=Tricho 0.061 14.6 0.0 1.2 10.4 0.0 2.1 1 tr|A2FNV4|A2FNV4_TRIVA Phosphoethanolamine N-methyltransfera 0.24 12.7 0.0 0.4 12.0 0.0 1.5 1 tr|A2EQY4|A2EQY4_TRIVA Uncharacterized protein OS=Trichomona Domain annotation for each sequence (and alignments): >> tr|A2F0C3|A2F0C3_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_292510 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 248.2 0.1 3.8e-77 2.1e-73 7 219 .] 24 233 .] 18 233 .] 0.95 Alignments for each domain: == domain 1 score: 248.2 bits; conditional E-value: 3.8e-77 -HHHHHHHHHHHHHHHHHS-HHHHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHC.TS-TTS-EEEES-TT-HHHHH--S CS Methyltransf_8 7 kkrldgarfrflneklytgesskavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklk.kkkdnlvvadlGcGeakiaeavre 92 +++l+g++fr+lneklyt++s++a+++f ++p+ f+ h+gf+ q k WP P+d +i ++k + ++ v+ad+GcG+akia +v + tr|A2F0C3|A2F0C3_TRIVA 24 RQQLEGSKFRMLNEKLYTCTSTEAKEFFDKQPQYFNTMHDGFQIQAKTWPIVPVDAVIDWIKnSIPKTAVIADMGCGDAKIAATVPN 110 589***********************************************************4568999*************88877 PP -..EEEEESS-SSTTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S-HHHHHHHHHCTTEE CS Methyltransf_8 93 kekvrsfdlvavnervvacdlakvPledesvdvavfclslmgtnladflkeanrvlkvGGllkvaevksrfesvklfaraltklGfe 179 + v+sfd++a n+rv+ cd+++ Pled+svdv+vf lslmgtn+ df++eanr+lk+ G l v ev+sr+e+ ++fa+ + +Gf+ tr|A2F0C3|A2F0C3_TRIVA 111 T--VHSFDFKARNSRVTQCDMSHTPLEDKSVDVVVFVLSLMGTNVSDFIREANRILKPNGKLLVVEVTSRIENADKFANGICAIGFD 195 7..************************************************************************************ PP EEEEE--STTEEEEEEEE-SSS-TT---GG--------XX CS Methyltransf_8 180 vkskdlsnkqfvlfefkkvekkgkkrelglklkpclykkr 219 ++k+ +++f+ fefkk k+ + l l pc+yk+r tr|A2F0C3|A2F0C3_TRIVA 196 LTKKKDLTTHFTWFEFKKGAPKNV--SGDLTLAPCIYKRR 233 *****************9865443..44789********9 PP >> tr|A2FK19|A2FK19_TRIVA Methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_346300 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.5 0.1 3.6e-07 0.002 63 159 .. 81 179 .. 78 188 .. 0.85 2 ? -1.3 0.0 0.8 4.5e+03 122 149 .. 203 230 .. 200 232 .. 0.88 Alignments for each domain: == domain 1 score: 19.5 bits; conditional E-value: 3.6e-07 HHHHHCTS-TTS-EEEES-TT-HHHHH--S-..EEEEESS-SSTT.EEES-TTS-S--TT-EEEEEE.ES---SS-HHHHHHHHHHH CS Methyltransf_8 63 iirklkkkkdnlvvadlGcGeakiaeavrekekvrsfdlvavner.vvacdlakvPledesvdvavf.clslmgtnladflkeanrv 147 +i l k +n++ +d+ + +a++ +k + +d +++ r dl+ + d+ +dv+v c+ ++ + ++ ke++rv tr|A2FK19|A2FK19_TRIVA 81 VISALAGKTGNVIGIDMTQEQIDVANEAIAYHKEHILDASPIEFRkGFIEDLRAANIPDNFADVVVSnCVINLSPQKKEVFKEIYRV 167 5677778888888899999999999888889999999999999651566799999999******99549999999999********* PP EEEEEEEEEEEE CS Methyltransf_8 148 lkvGGllkvaev 159 lk GG l+ ++v tr|A2FK19|A2FK19_TRIVA 168 LKEGGELHFSDV 179 ******998877 PP == domain 2 score: -1.3 bits; conditional E-value: 0.8 -EEEEEEES---SS-HHHHHHHHHHHEE CS Methyltransf_8 122 svdvavfclslmgtnladflkeanrvlk 149 ++d+ f +mg ++df r+l tr|A2FK19|A2FK19_TRIVA 203 AMDINTFIAYMMGVGFKDFRVVTSRILN 230 6899999999********9999999985 PP >> tr|A2FH79|A2FH79_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_123080 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.0 0.0 2.6e-07 0.0014 71 157 .. 44 141 .. 24 196 .. 0.73 Alignments for each domain: == domain 1 score: 20.0 bits; conditional E-value: 2.6e-07 -TTS-EEEES-TT-HHH...HH--S-..EEEEESS....-SSTTEEES-TTS-S--TT-EEEEEEES---....SS-HHHHHHHHHH CS Methyltransf_8 71 kdnlvvadlGcGeakia...eavrekekvrsfdlv....avnervvacdlakvPledesvdvavfclslm....gtnladflkeanr 146 +d +++d+GcG+ + +v + s+ l + n+ v d k+P++ + d a++ + + + +ke+ r tr|A2FH79|A2FH79_TRIVA 44 PDYSTLIDVGCGNGRNIginPKVYDVGTDFSLSLIkiakSKNKSVFCADALKLPVKSDYFDNAICIAVIHhfasEERRIQCMKEICR 130 6677899******99552323444444445666642222568889999********98888877544332111134455789***** PP HEEEEEEEEEE CS Methyltransf_8 147 vlkvGGllkva 157 ++kvGG +v+ tr|A2FH79|A2FH79_TRIVA 131 IIKVGGTAFVT 141 ******99886 PP >> tr|A2GIP8|A2GIP8_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_031080 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 8e-07 0.0045 65 158 .. 38 142 .. 30 157 .. 0.72 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 8e-07 HHHCTS-TTS-EEEES-TT-H...HHHH--S-..EEEEESS-SST....TEEES-TTS-S--TT-EE..EEEEES---SS-..HHHH CS Methyltransf_8 65 rklkkkkdnlvvadlGcGeak...iaeavrekekvrsfdlvavne....rvvacdlakvPledesvd..vavfclslmgtn..ladf 140 +++++ + v+ d+GcG+ + i +++ + sf l + + ++ d k+Pl + d + + + +t+ + tr|A2GIP8|A2GIP8_TRIVA 38 NWVNSLEPYSVILDIGCGNGRnlgINKSIYNIGTDYSFALCKIAKsrnfQIFRADGLKIPLRSGVFDhiIQIAVIHHFATEnrRIQC 124 5677777889*********995445577888888899*998664422227999********97776633233334444443014578 PP HHHHHHHEEEEEEEEEEE CS Methyltransf_8 141 lkeanrvlkvGGllkvae 158 lke+ r+lk+ G +v+ tr|A2GIP8|A2GIP8_TRIVA 125 LKEIARLLKINGTAYVTA 142 ************999975 PP >> tr|A2DVE6|A2DVE6_TRIVA Methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_209040 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.1 0.0 3.9e-06 0.022 112 161 .. 128 178 .. 78 220 .. 0.89 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 3.9e-06 -TTS-S--TT-EEEEEE.ES---SS-HHHHHHHHHHHEEEEEEEEEEEEGG CS Methyltransf_8 112 dlakvPledesvdvavf.clslmgtnladflkeanrvlkvGGllkvaevks 161 dl + d+ +dv+v c+ ++ + ++ ke++rvlk GG l+ ++v s tr|A2DVE6|A2DVE6_TRIVA 128 DLHTANIPDNFADVVVSnCVINLSPQKKNVFKEIYRVLKDGGELHFSDVFS 178 55555667999999995499899999999****************999977 PP >> tr|A2EDP7|A2EDP7_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_309010 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 2.2e-05 0.12 58 159 .. 61 184 .. 40 201 .. 0.62 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.2e-05 -HHHHHHHHHCT.S-TTS-EEEES-TT-HHH..HH--S-..EEEEE...........SS-SSTT..EEES-TTS-S--TT-EEEEE. CS Methyltransf_8 58 nPldviirklkk.kkdnlvvadlGcGeakia..eavrekekvrsfd...........lvavner..vvacdlakvPledesvdvav. 127 +P d++ + l k ++ ++ +GcG++ ++ ++ kv +d l+ +++ + c+ +k+P +d++ d + tr|A2EDP7|A2EDP7_TRIVA 61 QPWDNLKNALGKyVTKDSTILSVGCGNSPMSaqLLKEGASKVYNVDfshvvidqmkaLHQEESNliWTECNATKLPYDDNTFDFVFd 147 566666666654135567788888988877633122333455555411111111111222222211468**************9873 PP ..EES---SS.....-HHHHHHHHHHHEEEEEEEEEEEE CS Methyltransf_8 128 ..fclslmgt.....nladflkeanrvlkvGGllkvaev 159 s+++t ++ ++l e+ rvlk+GG++ ae+ tr|A2EDP7|A2EDP7_TRIVA 148 kgTLDSFVATadsskQIPTMLSEVCRVLKPGGIF--AEI 184 32223444432222268889************97..555 PP >> tr|A2DMU5|A2DMU5_TRIVA Methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_254280 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.1 1.2e-05 0.067 72 105 .. 48 83 .. 34 97 .. 0.79 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.2e-05 TTS-EEEES-TT..-HHHHH--S-..EEEEESS-SS CS Methyltransf_8 72 dnlvvadlGcGe..akiaeavrekekvrsfdlvavn 105 + ++vadlGcG ia v ++v+sfdl +v tr|A2DMU5|A2DMU5_TRIVA 48 EGKIVADLGCGCgiLSIACLVMGAKEVHSFDLDPVS 83 66799***98751157889999999*******9986 PP >> tr|A2FNV4|A2FNV4_TRIVA Phosphoethanolamine N-methyltransferase-related protein OS=Trichomonas vaginalis OX=5722 GN=T # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.00022 1.2 63 154 .. 48 163 .. 44 178 .. 0.60 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00022 HHHHHCTS-TTS-EE.EES-TT-HHHHH--S..-..EEEEESS-S.....ST........TEEES-TTS-S--TT-EEE........ CS Methyltransf_8 63 iirklkkkkdnlvva.dlGcGeakiaeavre..kekvrsfdlvav.....ne........rvvacdlakvPledesvdv........ 125 i +++k++ ++ ++a ++GcG++ +++ + e + kv+s+d+ + e + + d +k+ d++ d tr|A2FNV4|A2FNV4_TRIVA 48 IEEQVKEHLKESSIAlNIGCGDSPMSHDMPEkyFSKVISIDVSPNaikemSErykdeprlEWKVMDCSKLDFPDNTFDFifdkgtfd 134 556677665555554399999999996654411679999998753111111111111111234567788888888887633333333 PP EEEES---SS-HHHHHHHHHHHEEEEEEE CS Methyltransf_8 126 avfclslmgtnladflkeanrvlkvGGll 154 a+ c + + ++e++rvlk+GG l tr|A2FNV4|A2FNV4_TRIVA 135 AISCGVNGDEIIWASMQEIHRVLKPGGKL 163 45554444444567889999999999976 PP >> tr|A2EQY4|A2EQY4_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_040100 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 7.2e-05 0.4 108 154 .. 116 170 .. 65 186 .. 0.74 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 7.2e-05 EEES-TTS-S--TT-EEEEE........EES---SS-HHHHHHHHHHHEEEEEEE CS Methyltransf_8 108 vvacdlakvPledesvdvav........fclslmgtnladflkeanrvlkvGGll 154 ++ d++++ +s d+++ +c ++ ++ ke+ rvlk+GG + tr|A2EQY4|A2EQY4_TRIVA 116 FEVGDIRNLEYRKNSFDLVIdkgtmdsmMCAETSQHDIGKMFKEISRVLKPGGTF 170 55667777777777777666333111114555556789999************86 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (219 nodes) Target sequences: 50190 (17055200 residues searched) Passed MSV filter: 1925 (0.0383543); expected 1003.8 (0.02) Passed bias filter: 1102 (0.0219566); expected 1003.8 (0.02) Passed Vit filter: 41 (0.000816896); expected 50.2 (0.001) Passed Fwd filter: 9 (0.000179319); expected 0.5 (1e-05) Initial search space (Z): 50190 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.27u 0.01s 00:00:00.28 Elapsed: 00:00:00.12 # Mc/sec: 31125.74 // [ok]