# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_8.hmm.txt
# target sequence database: proteomes/Trichomonas_vaginalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_8 [M=219]
Accession: PF05148.15
Description: Hypothetical methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.7e-73 248.6 0.1 2.1e-73 248.2 0.1 1.0 1 tr|A2F0C3|A2F0C3_TRIVA Uncharacterized protein OS=Trichomona
0.00058 21.2 0.1 0.002 19.5 0.1 1.7 2 tr|A2FK19|A2FK19_TRIVA Methyltransferase, putative OS=Tricho
0.0011 20.3 0.0 0.0014 20.0 0.0 1.3 1 tr|A2FH79|A2FH79_TRIVA Uncharacterized protein OS=Trichomona
0.0024 19.2 0.0 0.0045 18.3 0.0 1.3 1 tr|A2GIP8|A2GIP8_TRIVA Uncharacterized protein OS=Trichomona
------ inclusion threshold ------
0.015 16.6 0.0 0.022 16.1 0.0 1.4 1 tr|A2DVE6|A2DVE6_TRIVA Methyltransferase, putative OS=Tricho
0.036 15.4 0.0 0.12 13.6 0.0 1.8 1 tr|A2EDP7|A2EDP7_TRIVA Uncharacterized protein OS=Trichomona
0.039 15.3 0.1 0.067 14.5 0.1 1.4 1 tr|A2DMU5|A2DMU5_TRIVA Methyltransferase, putative OS=Tricho
0.061 14.6 0.0 1.2 10.4 0.0 2.1 1 tr|A2FNV4|A2FNV4_TRIVA Phosphoethanolamine N-methyltransfera
0.24 12.7 0.0 0.4 12.0 0.0 1.5 1 tr|A2EQY4|A2EQY4_TRIVA Uncharacterized protein OS=Trichomona
Domain annotation for each sequence (and alignments):
>> tr|A2F0C3|A2F0C3_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_292510 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 248.2 0.1 3.8e-77 2.1e-73 7 219 .] 24 233 .] 18 233 .] 0.95
Alignments for each domain:
== domain 1 score: 248.2 bits; conditional E-value: 3.8e-77
-HHHHHHHHHHHHHHHHHS-HHHHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHC.TS-TTS-EEEES-TT-HHHHH--S CS
Methyltransf_8 7 kkrldgarfrflneklytgesskavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklk.kkkdnlvvadlGcGeakiaeavre 92
+++l+g++fr+lneklyt++s++a+++f ++p+ f+ h+gf+ q k WP P+d +i ++k + ++ v+ad+GcG+akia +v +
tr|A2F0C3|A2F0C3_TRIVA 24 RQQLEGSKFRMLNEKLYTCTSTEAKEFFDKQPQYFNTMHDGFQIQAKTWPIVPVDAVIDWIKnSIPKTAVIADMGCGDAKIAATVPN 110
589***********************************************************4568999*************88877 PP
-..EEEEESS-SSTTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S-HHHHHHHHHCTTEE CS
Methyltransf_8 93 kekvrsfdlvavnervvacdlakvPledesvdvavfclslmgtnladflkeanrvlkvGGllkvaevksrfesvklfaraltklGfe 179
+ v+sfd++a n+rv+ cd+++ Pled+svdv+vf lslmgtn+ df++eanr+lk+ G l v ev+sr+e+ ++fa+ + +Gf+
tr|A2F0C3|A2F0C3_TRIVA 111 T--VHSFDFKARNSRVTQCDMSHTPLEDKSVDVVVFVLSLMGTNVSDFIREANRILKPNGKLLVVEVTSRIENADKFANGICAIGFD 195
7..************************************************************************************ PP
EEEEE--STTEEEEEEEE-SSS-TT---GG--------XX CS
Methyltransf_8 180 vkskdlsnkqfvlfefkkvekkgkkrelglklkpclykkr 219
++k+ +++f+ fefkk k+ + l l pc+yk+r
tr|A2F0C3|A2F0C3_TRIVA 196 LTKKKDLTTHFTWFEFKKGAPKNV--SGDLTLAPCIYKRR 233
*****************9865443..44789********9 PP
>> tr|A2FK19|A2FK19_TRIVA Methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_346300 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.5 0.1 3.6e-07 0.002 63 159 .. 81 179 .. 78 188 .. 0.85
2 ? -1.3 0.0 0.8 4.5e+03 122 149 .. 203 230 .. 200 232 .. 0.88
Alignments for each domain:
== domain 1 score: 19.5 bits; conditional E-value: 3.6e-07
HHHHHCTS-TTS-EEEES-TT-HHHHH--S-..EEEEESS-SSTT.EEES-TTS-S--TT-EEEEEE.ES---SS-HHHHHHHHHHH CS
Methyltransf_8 63 iirklkkkkdnlvvadlGcGeakiaeavrekekvrsfdlvavner.vvacdlakvPledesvdvavf.clslmgtnladflkeanrv 147
+i l k +n++ +d+ + +a++ +k + +d +++ r dl+ + d+ +dv+v c+ ++ + ++ ke++rv
tr|A2FK19|A2FK19_TRIVA 81 VISALAGKTGNVIGIDMTQEQIDVANEAIAYHKEHILDASPIEFRkGFIEDLRAANIPDNFADVVVSnCVINLSPQKKEVFKEIYRV 167
5677778888888899999999999888889999999999999651566799999999******99549999999999********* PP
EEEEEEEEEEEE CS
Methyltransf_8 148 lkvGGllkvaev 159
lk GG l+ ++v
tr|A2FK19|A2FK19_TRIVA 168 LKEGGELHFSDV 179
******998877 PP
== domain 2 score: -1.3 bits; conditional E-value: 0.8
-EEEEEEES---SS-HHHHHHHHHHHEE CS
Methyltransf_8 122 svdvavfclslmgtnladflkeanrvlk 149
++d+ f +mg ++df r+l
tr|A2FK19|A2FK19_TRIVA 203 AMDINTFIAYMMGVGFKDFRVVTSRILN 230
6899999999********9999999985 PP
>> tr|A2FH79|A2FH79_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_123080 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.0 0.0 2.6e-07 0.0014 71 157 .. 44 141 .. 24 196 .. 0.73
Alignments for each domain:
== domain 1 score: 20.0 bits; conditional E-value: 2.6e-07
-TTS-EEEES-TT-HHH...HH--S-..EEEEESS....-SSTTEEES-TTS-S--TT-EEEEEEES---....SS-HHHHHHHHHH CS
Methyltransf_8 71 kdnlvvadlGcGeakia...eavrekekvrsfdlv....avnervvacdlakvPledesvdvavfclslm....gtnladflkeanr 146
+d +++d+GcG+ + +v + s+ l + n+ v d k+P++ + d a++ + + + +ke+ r
tr|A2FH79|A2FH79_TRIVA 44 PDYSTLIDVGCGNGRNIginPKVYDVGTDFSLSLIkiakSKNKSVFCADALKLPVKSDYFDNAICIAVIHhfasEERRIQCMKEICR 130
6677899******99552323444444445666642222568889999********98888877544332111134455789***** PP
HEEEEEEEEEE CS
Methyltransf_8 147 vlkvGGllkva 157
++kvGG +v+
tr|A2FH79|A2FH79_TRIVA 131 IIKVGGTAFVT 141
******99886 PP
>> tr|A2GIP8|A2GIP8_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_031080 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.3 0.0 8e-07 0.0045 65 158 .. 38 142 .. 30 157 .. 0.72
Alignments for each domain:
== domain 1 score: 18.3 bits; conditional E-value: 8e-07
HHHCTS-TTS-EEEES-TT-H...HHHH--S-..EEEEESS-SST....TEEES-TTS-S--TT-EE..EEEEES---SS-..HHHH CS
Methyltransf_8 65 rklkkkkdnlvvadlGcGeak...iaeavrekekvrsfdlvavne....rvvacdlakvPledesvd..vavfclslmgtn..ladf 140
+++++ + v+ d+GcG+ + i +++ + sf l + + ++ d k+Pl + d + + + +t+ +
tr|A2GIP8|A2GIP8_TRIVA 38 NWVNSLEPYSVILDIGCGNGRnlgINKSIYNIGTDYSFALCKIAKsrnfQIFRADGLKIPLRSGVFDhiIQIAVIHHFATEnrRIQC 124
5677777889*********995445577888888899*998664422227999********97776633233334444443014578 PP
HHHHHHHEEEEEEEEEEE CS
Methyltransf_8 141 lkeanrvlkvGGllkvae 158
lke+ r+lk+ G +v+
tr|A2GIP8|A2GIP8_TRIVA 125 LKEIARLLKINGTAYVTA 142
************999975 PP
>> tr|A2DVE6|A2DVE6_TRIVA Methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_209040 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 16.1 0.0 3.9e-06 0.022 112 161 .. 128 178 .. 78 220 .. 0.89
Alignments for each domain:
== domain 1 score: 16.1 bits; conditional E-value: 3.9e-06
-TTS-S--TT-EEEEEE.ES---SS-HHHHHHHHHHHEEEEEEEEEEEEGG CS
Methyltransf_8 112 dlakvPledesvdvavf.clslmgtnladflkeanrvlkvGGllkvaevks 161
dl + d+ +dv+v c+ ++ + ++ ke++rvlk GG l+ ++v s
tr|A2DVE6|A2DVE6_TRIVA 128 DLHTANIPDNFADVVVSnCVINLSPQKKNVFKEIYRVLKDGGELHFSDVFS 178
55555667999999995499899999999****************999977 PP
>> tr|A2EDP7|A2EDP7_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_309010 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.6 0.0 2.2e-05 0.12 58 159 .. 61 184 .. 40 201 .. 0.62
Alignments for each domain:
== domain 1 score: 13.6 bits; conditional E-value: 2.2e-05
-HHHHHHHHHCT.S-TTS-EEEES-TT-HHH..HH--S-..EEEEE...........SS-SSTT..EEES-TTS-S--TT-EEEEE. CS
Methyltransf_8 58 nPldviirklkk.kkdnlvvadlGcGeakia..eavrekekvrsfd...........lvavner..vvacdlakvPledesvdvav. 127
+P d++ + l k ++ ++ +GcG++ ++ ++ kv +d l+ +++ + c+ +k+P +d++ d +
tr|A2EDP7|A2EDP7_TRIVA 61 QPWDNLKNALGKyVTKDSTILSVGCGNSPMSaqLLKEGASKVYNVDfshvvidqmkaLHQEESNliWTECNATKLPYDDNTFDFVFd 147
566666666654135567788888988877633122333455555411111111111222222211468**************9873 PP
..EES---SS.....-HHHHHHHHHHHEEEEEEEEEEEE CS
Methyltransf_8 128 ..fclslmgt.....nladflkeanrvlkvGGllkvaev 159
s+++t ++ ++l e+ rvlk+GG++ ae+
tr|A2EDP7|A2EDP7_TRIVA 148 kgTLDSFVATadsskQIPTMLSEVCRVLKPGGIF--AEI 184
32223444432222268889************97..555 PP
>> tr|A2DMU5|A2DMU5_TRIVA Methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_254280 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.5 0.1 1.2e-05 0.067 72 105 .. 48 83 .. 34 97 .. 0.79
Alignments for each domain:
== domain 1 score: 14.5 bits; conditional E-value: 1.2e-05
TTS-EEEES-TT..-HHHHH--S-..EEEEESS-SS CS
Methyltransf_8 72 dnlvvadlGcGe..akiaeavrekekvrsfdlvavn 105
+ ++vadlGcG ia v ++v+sfdl +v
tr|A2DMU5|A2DMU5_TRIVA 48 EGKIVADLGCGCgiLSIACLVMGAKEVHSFDLDPVS 83
66799***98751157889999999*******9986 PP
>> tr|A2FNV4|A2FNV4_TRIVA Phosphoethanolamine N-methyltransferase-related protein OS=Trichomonas vaginalis OX=5722 GN=T
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.4 0.0 0.00022 1.2 63 154 .. 48 163 .. 44 178 .. 0.60
Alignments for each domain:
== domain 1 score: 10.4 bits; conditional E-value: 0.00022
HHHHHCTS-TTS-EE.EES-TT-HHHHH--S..-..EEEEESS-S.....ST........TEEES-TTS-S--TT-EEE........ CS
Methyltransf_8 63 iirklkkkkdnlvva.dlGcGeakiaeavre..kekvrsfdlvav.....ne........rvvacdlakvPledesvdv........ 125
i +++k++ ++ ++a ++GcG++ +++ + e + kv+s+d+ + e + + d +k+ d++ d
tr|A2FNV4|A2FNV4_TRIVA 48 IEEQVKEHLKESSIAlNIGCGDSPMSHDMPEkyFSKVISIDVSPNaikemSErykdeprlEWKVMDCSKLDFPDNTFDFifdkgtfd 134
556677665555554399999999996654411679999998753111111111111111234567788888888887633333333 PP
EEEES---SS-HHHHHHHHHHHEEEEEEE CS
Methyltransf_8 126 avfclslmgtnladflkeanrvlkvGGll 154
a+ c + + ++e++rvlk+GG l
tr|A2FNV4|A2FNV4_TRIVA 135 AISCGVNGDEIIWASMQEIHRVLKPGGKL 163
45554444444567889999999999976 PP
>> tr|A2EQY4|A2EQY4_TRIVA Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_040100 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.0 0.0 7.2e-05 0.4 108 154 .. 116 170 .. 65 186 .. 0.74
Alignments for each domain:
== domain 1 score: 12.0 bits; conditional E-value: 7.2e-05
EEES-TTS-S--TT-EEEEE........EES---SS-HHHHHHHHHHHEEEEEEE CS
Methyltransf_8 108 vvacdlakvPledesvdvav........fclslmgtnladflkeanrvlkvGGll 154
++ d++++ +s d+++ +c ++ ++ ke+ rvlk+GG +
tr|A2EQY4|A2EQY4_TRIVA 116 FEVGDIRNLEYRKNSFDLVIdkgtmdsmMCAETSQHDIGKMFKEISRVLKPGGTF 170
55667777777777777666333111114555556789999************86 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (219 nodes)
Target sequences: 50190 (17055200 residues searched)
Passed MSV filter: 1925 (0.0383543); expected 1003.8 (0.02)
Passed bias filter: 1102 (0.0219566); expected 1003.8 (0.02)
Passed Vit filter: 41 (0.000816896); expected 50.2 (0.001)
Passed Fwd filter: 9 (0.000179319); expected 0.5 (1e-05)
Initial search space (Z): 50190 [actual number of targets]
Domain search space (domZ): 9 [number of targets reported over threshold]
# CPU time: 0.27u 0.01s 00:00:00.28 Elapsed: 00:00:00.12
# Mc/sec: 31125.74
//
[ok]