# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Methyltransf_8.hmm.txt
# target sequence database: proteomes/Trichoplax_adhaerens.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Methyltransf_8 [M=219]
Accession: PF05148.15
Description: Hypothetical methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.3e-80 269.8 0.2 1.5e-80 269.5 0.2 1.0 1 tr|B3RTE1|B3RTE1_TRIAD Uncharacterized protein OS=Trichoplax
1e-07 31.5 0.0 1.1e-05 24.8 0.0 2.4 2 tr|B3RJV9|B3RJV9_TRIAD 2-methoxy-6-polyprenyl-1,4-benzoquino
4.9e-07 29.2 0.0 1.1e-06 28.0 0.0 1.5 1 tr|B3S9J7|B3S9J7_TRIAD Uncharacterized protein OS=Trichoplax
8.3e-06 25.2 0.1 1.7e-05 24.2 0.1 1.4 1 tr|B3RYI8|B3RYI8_TRIAD Uncharacterized protein OS=Trichoplax
4.7e-05 22.7 0.0 0.0001 21.6 0.0 1.5 1 tr|B3S9J8|B3S9J8_TRIAD Uncharacterized protein OS=Trichoplax
0.00011 21.5 0.0 0.00015 21.1 0.0 1.3 1 tr|B3SAR5|B3SAR5_TRIAD Uncharacterized protein OS=Trichoplax
0.0002 20.6 0.0 0.00039 19.7 0.0 1.5 1 tr|B3RP82|B3RP82_TRIAD Uncharacterized protein OS=Trichoplax
0.00021 20.6 0.0 0.00045 19.5 0.0 1.6 1 tr|B3SAR8|B3SAR8_TRIAD Uncharacterized protein OS=Trichoplax
0.002 17.4 0.0 0.0058 15.9 0.0 1.6 1 tr|B3S042|B3S042_TRIAD Uncharacterized protein OS=Trichoplax
Domain annotation for each sequence (and alignments):
>> tr|B3RTE1|B3RTE1_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_22483 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 269.5 0.2 1.2e-83 1.5e-80 4 219 .] 34 251 .] 31 251 .] 0.95
Alignments for each domain:
== domain 1 score: 269.5 bits; conditional E-value: 1.2e-83
XXX-HHHHHHHHHHHHHHHHHS-HHHHHHHHHH-HHHHHHHHHHHHHHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH- CS
Methyltransf_8 4 akikkrldgarfrflneklytgesskavdlfkedpeafdlyhkgfrsqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeav 90
+k ++rl+++rfr++neklyt ++ +a+++fk dp++fd+yh gf++qv kWP nPld+ii ++++ ++l++adlGcGe ++a++v
tr|B3RTE1|B3RTE1_TRIAD 34 NKFAQRLQAGRFRWVNEKLYTIKGLEAFHMFKSDPNLFDIYHSGFQTQVDKWPINPLDNIIDFIRNRSKDLIIADLGCGEGRLAQSV 120
7899********************************************************************************888 PP
-S-..EEEEESS-SSTTEEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEEEEEEEEEGGG-S-HHHHHHHHHCTT CS
Methyltransf_8 91 rekekvrsfdlvavnervvacdlakvPledesvdvavfclslmgtnladflkeanrvlkvGGllkvaevksrfesvklfaraltklG 177
+k v s+dl++ ++++acd+a+ Pled vd++vfcl+lmgtnl d++kea+r+lk+GG+l +aev sr+e f+r l+ +G
tr|B3RTE1|B3RTE1_TRIAD 121 PNK--VYSIDLASRADHIIACDMANTPLEDAHVDMVVFCLALMGTNLLDYVKEAKRILKPGGILLIAEVLSRIEHEARFVRSLSMFG 205
776..********************************************************************************** PP
EEEEEEE--STTEEEEEEEE-SSS-TT---GG-....-------XX CS
Methyltransf_8 178 fevkskdlsnkqfvlfefkkvekkgkkrelglk....lkpclykkr 219
f+ k+k + +k+f+ f+f v+k+ kk + ++ lkpc+ykkr
tr|B3RTE1|B3RTE1_TRIAD 206 FKLKEKLVLSKMFIRFQFVEVSKQLKKSNTEVAnlslLKPCVYKKR 251
**********************88887766432222389******9 PP
>> tr|B3RJV9|B3RJV9_TRIAD 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial OS=Trichoplax adhaerens OX=10
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 4.4 0.0 0.015 19 61 125 .. 91 148 .. 45 151 .. 0.75
2 ! 24.8 0.0 8.5e-09 1.1e-05 110 160 .. 166 217 .. 159 230 .. 0.89
Alignments for each domain:
== domain 1 score: 4.4 bits; conditional E-value: 0.015
HHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..EEEEESS-SSTTEEES-TTS-S--TT-EEE CS
Methyltransf_8 61 dviirklkkkkdnlvvadlGcGeakiaeavrekekvrsfdlvavnervvacdlakvPledesvdv 125
d+++r+l+ + l ++d+G G k+ ++v+++ +d +e++ c ++ + ++ + dv
tr|B3RJV9|B3RJV9_TRIAD 91 DTFVRQLNLQS-GLNIVDVGGGTGKVNQRVKNS-----MDK-NTQENIPNCAISVIDINQSMLDV 148
66777777654.57799**********888876.....564.45667777777777777777776 PP
== domain 2 score: 24.8 bits; conditional E-value: 8.5e-09
ES-TTS-S--TT-EEEEEEES---.SS-HHHHHHHHHHHEEEEEEEEEEEEG CS
Methyltransf_8 110 acdlakvPledesvdvavfclslm.gtnladflkeanrvlkvGGllkvaevk 160
d ++P++d+s+d++ +++ +tn+++ + ea+r+l +GG + v e +
tr|B3RJV9|B3RJV9_TRIAD 166 KGDAENLPVKDSSADLVTAAFAIRnVTNIRKAISEAYRILTPGGRFSVLEFS 217
67899*************99999538********************999864 PP
>> tr|B3S9J7|B3S9J7_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_60933 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 28.0 0.0 8.8e-10 1.1e-06 60 152 .. 36 141 .. 16 148 .. 0.66
Alignments for each domain:
== domain 1 score: 28.0 bits; conditional E-value: 8.8e-10
HHHHHHHHCTS-TTS-EEEES-TT-HHH.HH--S-..EEEEE.......SS-SSTT..EEES-T...TS-S--TT-EEEEEEES--- CS
Methyltransf_8 60 ldviirklkkkkdnlvvadlGcGeakia.eavrekekvrsfd.......lvavner..vvacdl...akvPledesvdvavfclslm 133
+d + + ++++++ +d+GcG + + +++++ fd l+ +++ ++ l ++Pled+ vd++++ ++
tr|B3S9J7|B3S9J7_TRIAD 36 MDYLKQGINQQDKFDLAIDVGCGPGTSTqQYAPYFNRIIGFDhsatqidLARQDNHdpNITYQLspaENLPLEDNIVDLVICAQAIH 122
444455555677777788999998766522333455565555110000054444432222333333379****************** PP
SS-HHHHHHHHHHHEEEEE CS
Methyltransf_8 134 gtnladflkeanrvlkvGG 152
n+ +fl e+nrvlk+G
tr|B3S9J7|B3S9J7_TRIAD 123 WFNIDQFLSEVNRVLKPGT 141
****************994 PP
>> tr|B3RYI8|B3RYI8_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_26003 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 24.2 0.1 1.3e-08 1.7e-05 40 155 .. 403 528 .. 387 554 .. 0.71
Alignments for each domain:
== domain 1 score: 24.2 bits; conditional E-value: 1.3e-08
HHHHHHHHHHHHHCTSSS-HHHHHHHHHCTS-TTS-EEEES-TT-HHHHH--S-..E...EEEESS-S....STTEEES-TTS-S-- CS
Methyltransf_8 40 afdlyhkgfrsqvkkWPenPldviirklkkkkdnlvvadlGcGeakiaeavrekekv...rsfdlvav....nervvacdlakvPle 119
++++y + ++ + + P vi++ l + ++ +v d+GcG+ k + + v rs lv++ + +v+ cd+ ++P +
tr|B3RYI8|B3RYI8_TRIAD 403 VYNIYDN-IADHFSGTRHSPWPVIANFLTSLPEGSMVLDIGCGNGKYMNVNKSLYMVgcdRSSGLVSIcgerGFEVILCDILNLPFQ 488
5666654.3555666777899999**********************99555555555333456688864322457************ PP
TT-EEEEEEES--..-SS-..HHHHHHHHHHHEEEEEEEE CS
Methyltransf_8 120 desvdvavfclsl..mgtn..ladflkeanrvlkvGGllk 155
++ d ++ + ++t + lke r+l+ G+
tr|B3RYI8|B3RYI8_TRIAD 489 SQAFDACICIAVIhhLSTTkrRIEALKECIRILRRDGVAL 528
99999766543221123320134689********999754 PP
>> tr|B3S9J8|B3S9J8_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_60934 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.6 0.0 7.9e-08 0.0001 91 150 .. 97 161 .. 40 173 .. 0.62
Alignments for each domain:
== domain 1 score: 21.6 bits; conditional E-value: 7.9e-08
-S-..EEEEESS-SSTT...E..EES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEE CS
Methyltransf_8 91 rekekvrsfdlvavner...v..vacdlakvPledesvdvavfclslmgtnladflkeanrvlkv 150
+ + +d + +++ v ++ +P ed++vd++v+ ++ n+ +f e+nrvlk+
tr|B3S9J8|B3S9J8_TRIAD 97 GTDHSATQLDQARQENQhpnVtfQVSAAETLPFEDNTVDLVVCAQAIHWFNMDQFFAEVNRVLKP 161
4444444555443322211121134455789********************************96 PP
>> tr|B3SAR5|B3SAR5_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_61353 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.1 0.0 1.2e-07 0.00015 114 152 .. 99 138 .. 21 163 .. 0.84
Alignments for each domain:
== domain 1 score: 21.1 bits; conditional E-value: 1.2e-07
TS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEE.E CS
Methyltransf_8 114 akvPledesvdvavfclslmgtnladflkeanrvlkvG.G 152
++P ed+svd++ + +l g + ++f e+ r+lk+G G
tr|B3SAR5|B3SAR5_TRIAD 99 YQLPCEDNSVDLVTCAQALHGLDEEKFFAEVDRILKPGrG 138
689*********************************9944 PP
>> tr|B3RP82|B3RP82_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_53437 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.7 0.0 3e-07 0.00039 98 156 .. 102 165 .. 47 178 .. 0.79
Alignments for each domain:
== domain 1 score: 19.7 bits; conditional E-value: 3e-07
EEESS-SSTTEEES-TTS-S--TT-EEEEEEES---.....SS-HHHHHHHHHHHEEEEEEEEE CS
Methyltransf_8 98 sfdlvavnervvacdlakvPledesvdvavfclslm.....gtnladflkeanrvlkvGGllkv 156
+d + v+ +++ + +P +d+ d + c l l+df +e+nrvlk+ G++ v
tr|B3RP82|B3RP82_TRIAD 102 KLDQHQVQAELIQAQVPAIPFDDHQFDFICNCQMLHhlsggLPTLKDFFREINRVLKNNGMVIV 165
489999***********************9996554111113579***************9877 PP
>> tr|B3SAR8|B3SAR8_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_61356 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 19.5 0.0 3.6e-07 0.00045 111 152 .. 96 137 .. 14 160 .. 0.69
Alignments for each domain:
== domain 1 score: 19.5 bits; conditional E-value: 3.6e-07
S-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEEE CS
Methyltransf_8 111 cdlakvPledesvdvavfclslmgtnladflkeanrvlkvGG 152
++P +d+svd++ + +l + ++f e++rvlk+G
tr|B3SAR8|B3SAR8_TRIAD 96 GSAYELPCDDNSVDLVTCAQALHCLDEEKFFAEVERVLKPGT 137
344689*********************************994 PP
>> tr|B3S042|B3S042_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_64033 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.9 0.0 4.5e-06 0.0058 54 152 .. 27 141 .. 11 148 .. 0.69
Alignments for each domain:
== domain 1 score: 15.9 bits; conditional E-value: 4.5e-06
TSSS-HHHHHHHHHCTS-TTS...-EEEES-TT-HHHHH.--S-..EEEEE.....SS-SSTTEEES-T.......TS-S--TT-EE CS
Methyltransf_8 54 kWPenPldviirklkkkkdnl...vvadlGcGeakiaea.vrekekvrsfd.....lvavnervvacdl.......akvPledesvd 124
+P + ++i++ l k+d + +d+GcG + ++ r +++v+ +d ++ ne+ + ++ ++P + +svd
tr|B3S042|B3S042_TRIAD 27 TYPAEVYEQILQFLTGKDDRVkydLAVDVGCGSGQSTKPlARYFTQVIGLDpsqgqIQQGNEKKENANVtlqvgsgEQLPCHSNSVD 113
567777777777777555543111568999999998854156688999998443333333444333332111133379********* PP
EEEEES---SS-HHHHHHHHHHHEEEEE CS
Methyltransf_8 125 vavfclslmgtnladflkeanrvlkvGG 152
+ + s+ + ++f ea rvlk+G
tr|B3S042|B3S042_TRIAD 114 LLTCAQSFHWLDEKKFFAEADRVLKPGT 141
*************************994 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (219 nodes)
Target sequences: 11518 (5222075 residues searched)
Passed MSV filter: 299 (0.0259594); expected 230.4 (0.02)
Passed bias filter: 193 (0.0167564); expected 230.4 (0.02)
Passed Vit filter: 22 (0.00191005); expected 11.5 (0.001)
Passed Fwd filter: 9 (0.000781386); expected 0.1 (1e-05)
Initial search space (Z): 11518 [actual number of targets]
Domain search space (domZ): 9 [number of targets reported over threshold]
# CPU time: 0.10u 0.00s 00:00:00.10 Elapsed: 00:00:00.04
# Mc/sec: 28590.86
//
[ok]