# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/PCIF1_WW.hmm.txt
# target sequence database:        proteomes/Petromyzon_marinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       PCIF1_WW  [M=172]
Accession:   PF12237.8
Description: Phosphorylated CTD interacting factor 1 WW domain
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    7.6e-69  230.3   0.0    1.1e-68  229.8   0.0    1.3  1  tr|S4RMM4|S4RMM4_PETMA  PDX1 C-terminal inhibiting factor 1 O
    8.1e-69  230.2   0.0    1.2e-68  229.7   0.0    1.3  1  tr|S4RMM7|S4RMM7_PETMA  PDX1 C-terminal inhibiting factor 1 O
  ------ inclusion threshold ------
      0.065   12.4   0.0         13    5.0   0.0    3.0  4  tr|S4RK72|S4RK72_PETMA  Uncharacterized protein OS=Petromyzon
      0.077   12.2   0.0         10    5.3   0.0    2.7  3  tr|S4RK48|S4RK48_PETMA  Uncharacterized protein OS=Petromyzon
       0.13   11.5   0.0         36    3.5   0.0    3.2  4  tr|Q2VGV6|Q2VGV6_PETMA  Variable lymphocyte receptor diversit


Domain annotation for each sequence (and alignments):
>> tr|S4RMM4|S4RMM4_PETMA  PDX1 C-terminal inhibiting factor 1 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  229.8   0.0   4.1e-72   1.1e-68       1     172 []     467     643 ..     467     643 .. 0.97

  Alignments for each domain:
  == domain 1  score: 229.8 bits;  conditional E-value: 4.1e-72
                PCIF1_WW   1 kLkeLyesseeddekleaflsrvfalllrYda.llg.....eaglqaalpeevfevLkkefgvsfecfAsPlncyfeqycsafpdtD 81 
                             kL++Ly+  ++dd+++e+fl+rv++ll+rY + ++g     +agl++alp  vfe+L+++fgv+fecfAsPlncyf+qycsaf+dtD
  tr|S4RMM4|S4RMM4_PETMA 467 KLEHLYRLGSTDDPRFEKFLARVWCLLRRYRQtMFGvggseGAGLHGALPVPVFEALHRHFGVTFECFASPLNCYFRQYCSAFADTD 553
                             89****************************751556889999********************************************* PP

                PCIF1_WW  82 ayFGsvGsffdfkpasgsfeanPPfveevleraaehieklLeaaeeesepLsfvvvvpewre..tealkkleesrykrkevvieake 166
                             +yFGs+G+++df+p+sgsfeanPPf ee+++++++h+e+l++++   +epLsf+v+vpewre  t al ++eesr+kr++v+++a e
  tr|S4RMM4|S4RMM4_PETMA 554 GYFGSRGPILDFNPVSGSFEANPPFGEELMNAMVDHFENLMSSS---TEPLSFIVFVPEWREpvTPALLRMEESRFKRRQVLVPAFE 637
                             ********************************************...9***************99********************** PP

                PCIF1_WW 167 heyreg 172
                             heyr+g
  tr|S4RMM4|S4RMM4_PETMA 638 HEYRNG 643
                             ***987 PP

>> tr|S4RMM7|S4RMM7_PETMA  PDX1 C-terminal inhibiting factor 1 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  229.7   0.0   4.4e-72   1.2e-68       1     172 []     433     609 ..     433     609 .. 0.97

  Alignments for each domain:
  == domain 1  score: 229.7 bits;  conditional E-value: 4.4e-72
                PCIF1_WW   1 kLkeLyesseeddekleaflsrvfalllrYda.llg.....eaglqaalpeevfevLkkefgvsfecfAsPlncyfeqycsafpdtD 81 
                             kL++Ly+  ++dd+++e+fl+rv++ll+rY + ++g     +agl++alp  vfe+L+++fgv+fecfAsPlncyf+qycsaf+dtD
  tr|S4RMM7|S4RMM7_PETMA 433 KLEHLYRLGSTDDPRFEKFLARVWCLLRRYRQtMFGvggseGAGLHGALPVPVFEALHRHFGVTFECFASPLNCYFRQYCSAFADTD 519
                             89****************************751556889999********************************************* PP

                PCIF1_WW  82 ayFGsvGsffdfkpasgsfeanPPfveevleraaehieklLeaaeeesepLsfvvvvpewre..tealkkleesrykrkevvieake 166
                             +yFGs+G+++df+p+sgsfeanPPf ee+++++++h+e+l++++   +epLsf+v+vpewre  t al ++eesr+kr++v+++a e
  tr|S4RMM7|S4RMM7_PETMA 520 GYFGSRGPILDFNPVSGSFEANPPFGEELMNAMVDHFENLMSSS---TEPLSFIVFVPEWREpvTPALLRMEESRFKRRQVLVPAFE 603
                             ********************************************...9***************99********************** PP

                PCIF1_WW 167 heyreg 172
                             heyr+g
  tr|S4RMM7|S4RMM7_PETMA 604 HEYRNG 609
                             ***987 PP

>> tr|S4RK72|S4RK72_PETMA  Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.0    0.0046        13      12      53 ..      40      81 ..      35      90 .. 0.87
   2 ?    2.8   0.0     0.022        59      14      53 ..      90     129 ..      83     137 .. 0.79
   3 ?    1.1   0.0     0.075     2e+02      19      52 ..     119     152 ..     106     161 .. 0.69
   4 ?    0.8   0.0     0.091   2.5e+02      17      52 ..     141     176 ..     129     205 .. 0.63

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0046
                PCIF1_WW 12 ddekleaflsrvfalllrYdallgeaglqaalpeevfevLkk 53
                            ++++ e +++ vf ll+  ++l+ +++  +a+p+ vf+ L++
  tr|S4RK72|S4RK72_PETMA 40 ESNRIESLPEGVFDLLVNLQHLHLNSNKLTAIPAGVFDKLTE 81
                            56678889999*************99************9987 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.022
                PCIF1_WW  14 ekleaflsrvfalllrYdallgeaglqaalpeevfevLkk 53 
                             ++l+a+++ vf  l++ ++l+ ++++  alp+ vf+ L++
  tr|S4RK72|S4RK72_PETMA  90 NQLTALPEGVFDRLVKLKELSLNTNQLLALPAGVFDSLTQ 129
                             4556777788888888888888888889999999999886 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.075
                PCIF1_WW  19 flsrvfalllrYdallgeaglqaalpeevfevLk 52 
                             +++ vf  l++ ++l  ++++ +alp+ vfe L 
  tr|S4RK72|S4RK72_PETMA 119 LPAGVFDSLTQLTTLYLSNNQLTALPAGVFERLV 152
                             4455666666666666677777888888888775 PP

  == domain 4  score: 0.8 bits;  conditional E-value: 0.091
                PCIF1_WW  17 eaflsrvfalllrYdallgeaglqaalpeevfevLk 52 
                             +a+++ vf  l+  ++++  ++  +a+p  +f+ L+
  tr|S4RK72|S4RK72_PETMA 141 TALPAGVFERLVNLQEFAVYNNKLTAVPDGIFDKLT 176
                             445555555555555555555555566666666555 PP

>> tr|S4RK48|S4RK48_PETMA  Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0    0.0038        10      12      53 ..      40      81 ..      34      89 .. 0.87
   2 ?    3.0   0.0     0.019        51      14      53 ..      90     129 ..      82     134 .. 0.78
   3 ?    2.2   0.0     0.034        91      19      53 ..     119     153 ..     105     178 .. 0.76

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0038
                PCIF1_WW 12 ddekleaflsrvfalllrYdallgeaglqaalpeevfevLkk 53
                            ++++ e +++ vf ll+  ++l+ +++  +a+p+ vf+ L++
  tr|S4RK48|S4RK48_PETMA 40 ESNRIESLPEGVFDLLVNLQHLHLNSNKLTAIPAGVFDKLTE 81
                            56778889999*************99************9987 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.019
                PCIF1_WW  14 ekleaflsrvfalllrYdallgeaglqaalpeevfevLkk 53 
                             ++l+a+++ vf  l++ ++l+ ++++  alp+ vf+ L++
  tr|S4RK48|S4RK48_PETMA  90 NQLTALPEGVFDRLVKLKELSLNTNQLLALPAGVFDSLTQ 129
                             4566777778888888888888888889999999998876 PP

  == domain 3  score: 2.2 bits;  conditional E-value: 0.034
                PCIF1_WW  19 flsrvfalllrYdallgeaglqaalpeevfevLkk 53 
                             +++ vf  l++ ++l  ++++ +alp+ vfe L k
  tr|S4RK48|S4RK48_PETMA 119 LPAGVFDSLTQLTTLYLSNNQLTALPAGVFERLVK 153
                             45556666677777777778888888888888876 PP

>> tr|Q2VGV6|Q2VGV6_PETMA  Variable lymphocyte receptor diversity region (Fragment) OS=Petromyzon marinus OX=7757 GN=VLR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0     0.054   1.5e+02      16      53 ..      41      78 ..      33      85 .. 0.84
   2 ?    0.9   0.0     0.086   2.3e+02      23      53 ..      72     102 ..      52     109 .. 0.62
   3 ?    3.5   0.0     0.013        36      13      56 ..     110     153 ..      99     159 .. 0.80
   4 ?    1.7   0.0     0.047   1.3e+02      14      68 ..     159     211 ..     154     225 .. 0.73

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.054
                PCIF1_WW 16 leaflsrvfalllrYdallgeaglqaalpeevfevLkk 53
                             ++++  vf  l+  + l+ ++++  +lp+ vf+ L++
  tr|Q2VGV6|Q2VGV6_PETMA 41 ITKLEPGVFDSLVNLQRLHLDQNQLVSLPAGVFDRLTQ 78
                            55677788888999999999999************987 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.086
                PCIF1_WW  23 vfalllrYdallgeaglqaalpeevfevLkk 53 
                             vf  l++ + l+ + ++ +alp  vf+ L++
  tr|Q2VGV6|Q2VGV6_PETMA  72 VFDRLTQLTYLNLGGNQLTALPVGVFDKLTQ 102
                             4444444333333347777888888888776 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.013
                PCIF1_WW  13 dekleaflsrvfalllrYdallgeaglqaalpeevfevLkkefg 56 
                             d++l+a+++ vf  l+  ++l  ++++ +alp  vf+ L++  g
  tr|Q2VGV6|Q2VGV6_PETMA 110 DNQLSALPAGVFDRLVNLQKLYLGENQLSALPVGVFDSLTQLTG 153
                             5667788888898899999988889999***********98655 PP

  == domain 4  score: 1.7 bits;  conditional E-value: 0.047
                PCIF1_WW  14 ekleaflsrvfalllrYdallgeaglqaalpeevfevLkkefgvsfecfAsPlnc 68 
                             ++l+a+++ vf  l++ + l+ ++++ +++p  +f+ Lk+  ++    f  P +c
  tr|Q2VGV6|Q2VGV6_PETMA 159 NQLQALPTGVFDNLTQLSILNMHTNQLKSIPRGAFDNLKSLTHI--YLFNNPWDC 211
                             56677778888888888888888888999999999999986554..457777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (172 nodes)
Target sequences:                        13539  (5048892 residues searched)
Passed MSV filter:                      1469  (0.108501); expected 270.8 (0.02)
Passed bias filter:                     1417  (0.104661); expected 270.8 (0.02)
Passed Vit filter:                       266  (0.0196469); expected 13.5 (0.001)
Passed Fwd filter:                         5  (0.000369303); expected 0.1 (1e-05)
Initial search space (Z):              13539  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.16u 0.00s 00:00:00.16 Elapsed: 00:00:00.05
# Mc/sec: 17368.19
//
[ok]