# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Pox_MCEL.hmm.txt
# target sequence database:        proteomes/Dictyostelium_discoideum.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Pox_MCEL  [M=333]
Accession:   PF03291.15
Description: mRNA capping enzyme
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    3.8e-71  239.4  12.2    6.6e-69  232.1  12.2    2.5  1  tr|Q54Y13|Q54Y13_DICDI  mRNA cap guanine-N7 methyltransferase
    4.5e-24   84.7   7.7    1.6e-22   79.6   7.7    2.3  1  tr|Q54IL6|Q54IL6_DICDI  Uncharacterized protein OS=Dictyostel
     0.0003   19.5   0.0      0.054   12.1   0.0    2.3  2  tr|Q54LU3|Q54LU3_DICDI  Uncharacterized protein OS=Dictyostel


Domain annotation for each sequence (and alignments):
>> tr|Q54Y13|Q54Y13_DICDI  mRNA cap guanine-N7 methyltransferase OS=Dictyostelium discoideum OX=44689 GN=DDB0205479 PE=3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  232.1  12.2   1.5e-72   6.6e-69       9     332 ..     106     438 ..      98     439 .. 0.95

  Alignments for each domain:
  == domain 1  score: 232.1 bits;  conditional E-value: 1.5e-72
                Pox_MCEL   9 evtdlvathynerpetgellkkRiastiiylrnlnNyiKslLiseyasktkldesnklkvLdldcgkGgDLeKyekgeIsklvatDi 95 
                             + +++v++hy ++++t   ++ R +s+ii l+n+nN++Ks+Li+ey ++++        v d++ gk gDL+K+ k++I++l+  Di
  tr|Q54Y13|Q54Y13_DICDI 106 KQNEIVSSHYDNKQNTP--IHIRAQSKIISLKNINNWVKSMLIQEYSKPNTI-------VFDICGGKLGDLQKWIKAQIKSLIVSDI 183
                             5689***********88..9*****************************999.......**************************** PP

                Pox_MCEL  96 aeesieeckeRYnklrsekkskyykFdaelirsdsfvssvrevfed......................................... 141
                             + es++++ eRY     ++k +y +F+ ++i+ d+f+s++ +vf +                                         
  tr|Q54Y13|Q54Y13_DICDI 184 SLESLKHGLERY-----NQKLNYIHFNITMIAVDCFSSKLLDVFPKqpssnklknkkkkinnnnneednsseseneqededddddye 265
                             ************.....77888999*******************7799*************************************99 PP

                Pox_MCEL 142 ..yelkfdivslQFaiHYsFeseekartvlrNvaellasGGkvlgTtpdgdelskltvkklkviekdlpsfgNsiyvvkfeeekiev 226
                                 lk+++vs+QFa+HYsF +ee ar +l+Nv+ +l+ GG+++gT+p++ ++    vkkl++++   ++fgN++++++f+e++++ 
  tr|Q54Y13|Q54Y13_DICDI 266 neELLKVNLVSCQFALHYSFRTEESARSLLKNVSSVLEDGGHFIGTIPNSCLI----VKKLRESK--SNKFGNEVFKIEFKEKEPNF 346
                             98889**********************************************99....*****996..899***************** PP

                Pox_MCEL 227 plfGakYeynledvvkdvpEyivkfealvklaeeYgleLvdkkdfaeiieesikke.lkklikrvskleerkstknfeelnrsalks 312
                             ++fG+ Y++ led+++ + Ey+v+ ++l +la++Y+le+v++++f+++i e+ k++  + l+++++          ++++n     +
  tr|Q54Y13|Q54Y13_DICDI 347 SAFGCAYNFFLEDAIDFLEEYLVHIDVLIELARDYQLEIVSHSNFHNLIYEKSKSKpSHDLLRKMN----------CFNSN-----N 418
                             ***********************************************9888866666888888887..........55554.....4 PP

                Pox_MCEL 313 tlgkdeeealsyYlvfvfeK 332
                             t+++ e++al +Y +fvf+K
  tr|Q54Y13|Q54Y13_DICDI 419 TISQAEWDALGIYKTFVFKK 438
                             67779**************9 PP

>> tr|Q54IL6|Q54IL6_DICDI  Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0188046 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.6   7.7   3.7e-26   1.6e-22      35     289 ..       9     283 ..       5     312 .. 0.87

  Alignments for each domain:
  == domain 1  score: 79.6 bits;  conditional E-value: 3.7e-26
                Pox_MCEL  35 tiiylrnlnNyiKslLiseyasktkldesnklkvLdldcgkGgDLeKyekgeIsklvatDiaeesieeckeRYnklrsekkskyykF 121
                              + +++ +  ++K++Li e ++++++         ++    G D  K+e ++I+++ +   ++    e+k+++   + +++     F
  tr|Q54IL6|Q54IL6_DICDI   9 SVWQFKAYQAWVKTILITELVEENDT-------AAEIYSAIGLDTGKWERAKIKRYYCFESSKSNATESKNKW---QAKNEP----F 81 
                             5667888999************9999.......4566667788888***************999999999998...333333....8 PP

                Pox_MCEL 122 daelirsdsfvssvrevfed.......................................yelkfdivslQFaiHYsFeseekartvl 169
                             +a +i+ d  + +++  +++                                       +  +fd++ +   +  sF+   +a+  +
  tr|Q54IL6|Q54IL6_DICDI  82 EADFITMDLNKDNIESFLQPipnnnnninnninnninnstnnninnnnnnnnnnninisKLPQFDVIACFDGLQNSFTDPTQAEQFI 168
                             8899999999888888888888889999***************************99977789************************ PP

                Pox_MCEL 170 rNvaellasGGkvlgTtpdgdelskltvkklkviekdlpsfgNsiyvvkfeeekievplfGakYeynledvvkdvpEyivkfealvk 256
                             +N++ +l+ GG+++g +pd+  l ++ +k++  +  +lp +  +++ ++f++e ++   fG+kY+    +   ++ E +v+f+ + +
  tr|Q54IL6|Q54IL6_DICDI 169 KNASSRLKVGGFFFGMMPDSSALWYKAQKETSSS--GLPIIKSNLFNITFDSEIQS--FFGCKYNLTIPTEL-NLSENLVHFPSFLN 250
                             ***********************99999999998..6**************66554..6***********99.************** PP

                Pox_MCEL 257 laeeYgleLvdkkdfaeiieesikkelkklikr 289
                             l+++Y+l Lv+  + +e+++e+ k++ +kl ++
  tr|Q54IL6|Q54IL6_DICDI 251 LCKKYNLTLVEATNLSEFYDENKKNYESKLKQS 283
                             **********************88877777543 PP

>> tr|Q54LU3|Q54LU3_DICDI  Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0186961 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.0   1.3e-05     0.054      66     129 ..      79     153 ..      67     163 .. 0.73
   2 !    5.1   0.0    0.0017       7.4     166     209 ..     163     203 ..     157     212 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 1.3e-05
                Pox_MCEL  66 lkvLdldcgkGgDLeKyekg..eIsklvatDiaeesieeckeRY.........nklrsekkskyykFdaelirsd 129
                              kv+d +cg G DL + e    +    v++Di+ e +e++k R              s++  + + Fda +ir++
  tr|Q54LU3|Q54LU3_DICDI  79 QKVMDCGCGAGKDLGRLESMveGNGIVVGMDISREMVECAKSRMshlpnvkifIGDASRIPIDDNYFDAYVIRCE 153
                             68************99986422566799***************96555554443344555555556666666665 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0017
                Pox_MCEL 166 rtvlrNvaellasGGkvlgTtpdgdelskltvkklkviekdlps 209
                             + v+  ++++++sGG++++T  d    s  + k++++i+k   +
  tr|Q54LU3|Q54LU3_DICDI 163 DLVISEMTRVIKSGGRIVITDADWSSTSVSIPKNIEEINK---K 203
                             5688899****************99999999999999964...3 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (333 nodes)
Target sequences:                        12739  (6856946 residues searched)
Passed MSV filter:                      1905  (0.149541); expected 254.8 (0.02)
Passed bias filter:                      149  (0.0116964); expected 254.8 (0.02)
Passed Vit filter:                        17  (0.00133448); expected 12.7 (0.001)
Passed Fwd filter:                         3  (0.000235497); expected 0.1 (1e-05)
Initial search space (Z):              12739  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.18u 0.01s 00:00:00.19 Elapsed: 00:00:00.07
# Mc/sec: 32619.47
//
[ok]