# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Pox_MCEL.hmm.txt
# target sequence database:        proteomes/Mus_musculus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Pox_MCEL  [M=333]
Accession:   PF03291.15
Description: mRNA capping enzyme
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence             Description
    ------- ------ -----    ------- ------ -----   ---- --  --------             -----------
     2e-125  418.6   3.3   3.2e-125  418.0   3.3    1.3  1  sp|Q9D0L8|MCES_MOUSE  mRNA cap guanine-N7 methyltransferase O
  ------ inclusion threshold ------
      0.078   12.4   0.0        1.4    8.3   0.0    2.0  1  sp|Q8BMS4|COQ3_MOUSE  Ubiquinone biosynthesis O-methyltransfe


Domain annotation for each sequence (and alignments):
>> sp|Q9D0L8|MCES_MOUSE  mRNA cap guanine-N7 methyltransferase OS=Mus musculus OX=10090 GN=Rnmt PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  418.0   3.3  2.8e-129  3.2e-125       4     333 .]     128     464 ..     125     464 .. 0.98

  Alignments for each domain:
  == domain 1  score: 418.0 bits;  conditional E-value: 2.8e-129
              Pox_MCEL   4 aetesevtdlvathynerpetgellkkRiastiiylrnlnNyiKslLiseyasktkldesnklkvLdldcgkGgDLeKyekgeIsklva 92 
                           ++ e++++++va+hyne++e g  l+kR++s+i+ylrn+nN+iKs+Li+e+++k++++++++++vLdl+cgkGgDL K++kg+Is+lv+
  sp|Q9D0L8|MCES_MOUSE 128 QKLEEGHSSAVAAHYNELQEVG--LAKRSQSRIFYLRNFNNWIKSILIGEILEKVRQRKTRDITVLDLGCGKGGDLLKWRKGRISRLVC 214
                           678999****************..***************************************************************** PP

              Pox_MCEL  93 tDiaeesieeckeRY..nklrsekkskyykFdaelirsdsfvssvrevfedyelkfdivslQFaiHYsFeseekartvlrNvaellasG 179
                           +Dia+ s+++c++RY  +++r+++++    F+ae+i++d+ ++ + e+f+d+e++fd++s+QFa+HYsFes+ +a+t+lrN++ +l++G
  sp|Q9D0L8|MCES_MOUSE 215 ADIADISMKQCQQRYedMRCRRDNEHI---FSAEFITADCSKELLVEKFRDPEMYFDVCSCQFACHYSFESQVQADTMLRNACGRLNPG 300
                           ***************777777777776...*********************************************************** PP

              Pox_MCEL 180 GkvlgTtpdgdelskltvkklkviekdlpsfgNsiyvvkfeeekievplfGakYeynledvvkdvpEyivkfealvklaeeYgleLvdk 268
                           G+++gTtp+++el    +++l+++e  ++sfgN+iy+vkf+ +k ++plfG+kY++nle+vv dvpE++v+f+ l+++a++Y+++L++k
  sp|Q9D0L8|MCES_MOUSE 301 GYFIGTTPNSFEL----IRRLEASE--TESFGNEIYTVKFQ-KKGNYPLFGCKYDFNLEGVV-DVPEFLVYFPLLTEMAKKYNMKLIYK 381
                           *************....*******6..**************.8999****************.************************** PP

              Pox_MCEL 269 kdfaeiieesikke.lkklikrvskleerkstknf.................eelnrsalkstlgkdeeealsyYlvfvfeKr 333
                           k+f e++ee+ik++ +k+l+kr+++le++++++n+                 ++++++ + +tl+k+e+ea+s+Ylvf+feK+
  sp|Q9D0L8|MCES_MOUSE 382 KTFLEFYEEKIKNNeNKMLLKRMQALEQYPAHENSklasekvgdythaaeylKKSQVRLPLGTLSKSEWEATSIYLVFAFEKQ 464
                           *************99*************************************9*****************************6 PP

>> sp|Q8BMS4|COQ3_MOUSE  Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Mus musculus OX=10090 GN=Coq3 PE=
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.0   0.00012       1.4      45     194 ..     128     261 ..      90     294 .. 0.65

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00012
              Pox_MCEL  45 yiKslLiseyasktkldesnklkvLdldcgkGgDLeKyekgeI.sklvatDiaeesieeckeRYnklrsekkskyykFdaelirsdsfv 132
                           +i+  L+++ as++  +  + +k+Ld++cg G  L     g++ ++ v++D+ +e i+ +++         k+            +  v
  sp|Q8BMS4|COQ3_MOUSE 128 FIRDNLLKTSASHHPGKPLSGMKILDVGCGGG--LLTEPLGRLgASVVGIDPVAENIKIAQHHKSFDPVLDKRI-----------QYKV 203
                           57777888888888888888899999999744..5555566653678899999999988876442222222222...........2222 PP

              Pox_MCEL 133 ssvrevfedyelkfd.ivslQFaiHYsFeseekartvlrNvaellasGGkvlgTtpdgdelsk 194
                            s++e++++ +  fd +v    + H s+      ++ ++   ++l++GG +++Tt++  +ls+
  sp|Q8BMS4|COQ3_MOUSE 204 CSLEEAVDESAECFDaVVASEVVEHVSH-----LEMFIQCCYQVLKPGGSLFITTVNKTQLSY 261
                           3344444444444442333344444442.....235556666777777777777777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (333 nodes)
Target sequences:                        22289  (11757923 residues searched)
Passed MSV filter:                       898  (0.0402889); expected 445.8 (0.02)
Passed bias filter:                      403  (0.0180807); expected 445.8 (0.02)
Passed Vit filter:                        31  (0.00139082); expected 22.3 (0.001)
Passed Fwd filter:                         2  (8.97304e-05); expected 0.2 (1e-05)
Initial search space (Z):              22289  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.28u 0.01s 00:00:00.29 Elapsed: 00:00:00.11
# Mc/sec: 35594.44
//
[ok]