# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Pox_MCEL.hmm.txt
# target sequence database: proteomes/Tetrahymena_thermophila.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Pox_MCEL [M=333]
Accession: PF03291.15
Description: mRNA capping enzyme
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
7.6e-47 160.6 10.5 7.6e-47 160.6 10.5 1.9 2 tr|Q231D4|Q231D4_TETTS mRNA cap guanine-N7 methyltransferase
3.4e-37 128.9 14.6 1.2e-20 74.5 4.7 2.3 2 tr|Q234L5|Q234L5_TETTS mRNA capping enzyme, large subunit fa
Domain annotation for each sequence (and alignments):
>> tr|Q231D4|Q231D4_TETTS mRNA cap guanine-N7 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -5.2 4.1 1.5 2.1e+04 282 312 .. 104 134 .. 89 164 .. 0.49
2 ! 160.6 10.5 5.7e-51 7.6e-47 6 332 .. 179 523 .. 172 524 .. 0.78
Alignments for each domain:
== domain 1 score: -5.2 bits; conditional E-value: 1.5
Pox_MCEL 282 elkklikrvsklee.rkstknfeelnrsalks 312
++kk+ +r + + + r+ + n+ e +rs++++
tr|Q231D4|Q231D4_TETTS 104 DVKKIQERKT-MQQvRERHDNSGEKKRSTMQQ 134
3444333332.222123333443333333332 PP
== domain 2 score: 160.6 bits; conditional E-value: 5.7e-51
Pox_MCEL 6 tesevtdlvathynerpetgellkkRiastiiylrnlnNyiKslLiseyasktkl.........desnklkvLdldcgkGgDLeKye 83
+ +e ++ +++ y++++ + +R+ + lrn+ N+iKs++i++y k+ e+ +l v++++cg+GgDL+K+
tr|Q231D4|Q231D4_TETTS 179 RVTEQQKTIQSGYEKKEALT--VLTRSVLETAELRNFHNWIKSVIIKKYSDDMKQiikkkedlrTETGQLFVMEIACGQGGDLKKWL 263
55667777888887777655..889999999******************8776665544433444566788**************** PP
Pox_MCEL 84 kgeIsklvatDiaeesieeckeRY..nklrsekkskyykFdaelirsd......sfvssvrevfed.......yelkfdivslQFai 155
++I +v++Di+ +s++e+++R + + +y kF++ +++ d f +++++ + +++ fdivs+Q a+
tr|Q231D4|Q231D4_TETTS 264 HADIGLYVGVDISFNSLKEASRRTkdIMEKLPPHWNYKKFKYGFYQKDgsastdEFWKHIHD---KdkdqdksKRFFFDIVSCQMAM 347
************************65444445566788899977765411100034444444...155599888999********** PP
Pox_MCEL 156 HYsFeseekartvlrNvaellasGGkvlgTtpdgdelskltvkklkvi.ekdlpsfgNsiyvvkfeeekiev.plfGakYeynledv 240
HY F se++ar + N++++l+ G++l+T d++ + k+++ + k +++ fgN+ +++ fe+ + v ++G kYe++l+d+
tr|Q231D4|Q231D4_TETTS 348 HYMFGSEQHARNFFSNATQRLNDQGYLLVTCSDSNAIVKKMRSRGKLDsTNNKYTFGNKYFSMAFENLNFPVgKPYGLKYEFYLQDA 434
*************************************999997666541567889***********99988889************9 PP
Pox_MCEL 241 v..........kdvpEyivkfealvklaeeYgleLvdkkdfaeiieesikkelkklikrvskleerkstknfeelnrsalkstlgkd 317
v k pEy+v+ ++l kla eY l+ ++ +f e+++++ ++++ l k++ l++ +++ ++ +
tr|Q231D4|Q231D4_TETTS 435 VgekdeatgqiKYTPEYLVELNNLNKLAMEYSLVVKENLNFIEFYKNY-RNKYGYLFKSMG-LDK---------FTNDH--PSIDPE 508
844333332224579*******************************99.677999999998.333.........22222..235556 PP
Pox_MCEL 318 eeealsyYlvfvfeK 332
+e+ + Y v vf+K
tr|Q231D4|Q231D4_TETTS 509 LWEISHCYRVIVFQK 523
666666666666665 PP
>> tr|Q234L5|Q234L5_TETTS mRNA capping enzyme, large subunit family protein OS=Tetrahymena thermophila (strain SB210) O
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 59.5 2.3 3.1e-20 4.2e-16 4 132 .. 255 393 .. 252 404 .. 0.74
2 ! 74.5 4.7 8.7e-25 1.2e-20 142 293 .. 479 641 .. 466 668 .. 0.79
Alignments for each domain:
== domain 1 score: 59.5 bits; conditional E-value: 3.1e-20
Pox_MCEL 4 aetesevtdlvathynerpetgellkkRiastiiylrnlnNyiKslLiseyasktkl........desnklkvLdldcgkGgDLeKy 82
++++s ++ v+++yn+ + +++R++ + +++r + N++Ks+Li++y + ++ n l +Ldl+cgkGgD +K+
tr|Q234L5|Q234L5_TETTS 255 HHHQSSSNNQVQNFYNNNKGFN--QQERKNLETFHIRVFHNWVKSVLIQKYGEIQRSivkaenakLPENYLYILDLACGKGGDHKKW 339
5667788899******988766..99*************************765544333211112346688*************** PP
Pox_MCEL 83 ekg.eIsklvatDiaeesieeckeRY.nklrsekkskyykFda..elirsdsfv 132
+ + ++++Dia e+++++ +R +l++ k++++y+ + +++ d+
tr|Q234L5|Q234L5_TETTS 340 LMHsHACFYIGVDIAMEALNQAYQRAiITLNEIKQNSRYHSNIkfGFFQKDCSC 393
875156679****************98555555555555444433555555554 PP
== domain 2 score: 74.5 bits; conditional E-value: 8.7e-25
Pox_MCEL 142 yelkfdivslQFaiHYsFeseekartvlrNvaellasGGkvlgTtpdgdelskltvkklkviekdlpsfgNsiyvvkfeeekiev.. 226
+ fd+vs+Q a+HY +eseek+r l N +++l+ G++l T dg+ + ++ k + + ++ + + +++kf++ +
tr|Q234L5|Q234L5_TETTS 479 GKYMFDVVSCQMAMHYMHESEEKVRNFLDNCTKRLNDQGFLLLTFTDGNAVLDIMKSKGQPTPEGGTIYSSKHFSMKFDNPVEQIdl 565
4678**********************************************9777777777777777778888888999965444477 PP
Pox_MCEL 227 ..plfGakYeynl........edvvkdvpEyivkfealvklaeeYgleLvdkkdfaeiieesikkelkklikrvskl 293
++G+kY ++l e+v+k vpEy+v+ + + + a+eY le ++ ++++e++ k + l+k+++
tr|Q234L5|Q234L5_TETTS 566 qqNPYGNKYGFYLqesvgsqvEGVIKYVPEYLVNVDLFIETAKEYSLEVKENNLLTDFYENN-KTPFADLLKQMKVT 641
889********9833333333457899**********************************9.66699999999822 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (333 nodes)
Target sequences: 26971 (16912921 residues searched)
Passed MSV filter: 5396 (0.200067); expected 539.4 (0.02)
Passed bias filter: 150 (0.00556153); expected 539.4 (0.02)
Passed Vit filter: 15 (0.000556153); expected 27.0 (0.001)
Passed Fwd filter: 2 (7.41537e-05); expected 0.3 (1e-05)
Initial search space (Z): 26971 [actual number of targets]
Domain search space (domZ): 2 [number of targets reported over threshold]
# CPU time: 0.42u 0.01s 00:00:00.43 Elapsed: 00:00:00.13
# Mc/sec: 43323.10
//
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