# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/RrnaAD.hmm.txt
# target sequence database: proteomes/Anolis_carolinensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: RrnaAD [M=265]
Accession: PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
3.9e-51 173.7 0.0 4.8e-51 173.4 0.0 1.1 1 tr|G1KHV6|G1KHV6_ANOCA rRNA adenine N(6)-methyltransferase O
5e-35 120.9 0.0 6.4e-35 120.6 0.0 1.1 1 tr|G1KDU6|G1KDU6_ANOCA rRNA adenine N(6)-methyltransferase O
7.3e-17 61.4 0.0 9e-17 61.0 0.0 1.1 1 tr|H9GIA2|H9GIA2_ANOCA rRNA adenine N(6)-methyltransferase O
8.8e-06 25.0 0.0 1.4e-05 24.4 0.0 1.2 1 tr|H9GMB0|H9GMB0_ANOCA Ribosomal RNA adenine dimethylase dom
0.0039 16.4 0.0 0.0053 15.9 0.0 1.2 1 tr|H9GC35|H9GC35_ANOCA Methyltransferase like 22 OS=Anolis c
------ inclusion threshold ------
0.046 12.8 0.0 0.096 11.8 0.0 1.5 1 tr|H9GDC5|H9GDC5_ANOCA tRNA methyltransferase 2 homolog A OS
0.059 12.5 0.0 0.12 11.5 0.0 1.4 1 tr|G1KC96|G1KC96_ANOCA Protein arginine methyltransferase 9
0.077 12.1 0.0 0.1 11.7 0.0 1.2 1 tr|H9GKF5|H9GKF5_ANOCA Protein-L-isoaspartate O-methyltransf
0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 tr|G1KBC8|G1KBC8_ANOCA Methyltransferase like 21C OS=Anolis
0.19 10.8 0.0 0.3 10.1 0.0 1.2 1 tr|R4GAD1|R4GAD1_ANOCA HemK methyltransferase family member
Domain annotation for each sequence (and alignments):
>> tr|G1KHV6|G1KHV6_ANOCA rRNA adenine N(6)-methyltransferase OS=Anolis carolinensis OX=28377 GN=DIMT1 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 173.4 0.0 2.6e-54 4.8e-51 28 237 .. 3 203 .. 1 221 [. 0.95
Alignments for each domain:
== domain 1 score: 173.4 bits; conditional E-value: 2.6e-54
GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHHCTTTCCCCEEEEEEE-- CS
RrnaAD 28 leekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeevtekdsihqeflvvanlP 111
l +++ vle+gpG+G++T+++++ +k vv+ E d +La +lqk+++ +++kl++ D+lk ++p + ++vanlP
tr|G1KHV6|G1KHV6_ANOCA 3 LYPTDVVLEVGPGTGNMTVKMLEKVKRVVACEVDVKLAGELQKRVQgtpLANKLEIKIGDVLKSDLPFFD----------ACVANLP 79
6689******************************************9999******************77..........8****** PP
TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S CS
RrnaAD 112 yeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveksifsPppkvdsalvelerkdedl 198
y+is+++v++ll ++r+ ++ ++l++q+efa rl+a+pgs +++rlsv++++++ v +++kv+k++f+Pppkv+s++v++e+k+++
tr|G1KHV6|G1KHV6_ANOCA 80 YQISSPFVFKLL-LHRPFFRCAVLMFQREFALRLVAKPGSPLYCRLSVNTQLLARVDHLMKVGKNNFKPPPKVESSVVRIEPKNPP- 164
************.788889******************************************************************8. PP
--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHC CS
RrnaAD 199 pqkdlkkyesvvrkllnrkrktlstslksllpggelqal 237
p + ++++ ++r++++rk+ktl ++++s+ ++ l+ +
tr|G1KHV6|G1KHV6_ANOCA 165 PPINFQEWDGLLRIVFVRKNKTLAAVFNSTAVKRLLEQN 203
89*************************999888776655 PP
>> tr|G1KDU6|G1KDU6_ANOCA rRNA adenine N(6)-methyltransferase OS=Anolis carolinensis OX=28377 GN=TFB1M PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 120.6 0.0 3.4e-38 6.4e-35 3 239 .. 28 278 .. 26 301 .. 0.89
Alignments for each domain:
== domain 1 score: 120.6 bits; conditional E-value: 3.4e-38
CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCG CS
RrnaAD 3 klrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls.kdeklkvvhqDflk 87
k+ k+++qnfl + + ++I + + ++ v e+gpG+G T+ +++ ++ ++E+d+r++ lq + +k+ vvh D+l+
tr|G1KDU6|G1KDU6_ANOCA 28 KAVKQLSQNFLLDLRLTDKIARSAGNLKDAHVCEVGPGPGGITRAILNAGvAELLLVEKDPRFIPGLQMLSEaAPGKVRVVHGDILT 114
566899*************************************99977666******************6558889*********** PP
HHHHHHHCT.....TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHH CS
RrnaAD 88 fetpeevte.....kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlre 162
+++ + + + + +++nlP +st+l+ ++le r g+ + +l +qke+ +rl+a+ g ++rsrls++++
tr|G1KDU6|G1KDU6_ANOCA 115 YKLGQAFPNhliknWEDDPPDIHIIGNLPFSVSTPLIIKWLEniskrdgPFRYGRTQLTLTFQKEVGERLTASTGTRQRSRLSIMSQ 201
*998877777776644555679**********************99998778899******************************** PP
HHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT CS
RrnaAD 163 aftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalss 239
+++ v +++ ++f P+p vd ++v ++ ++ ++ k e+vv+ ++ +rk + l+p++ + +
tr|G1KDU6|G1KDU6_ANOCA 202 YLCTVHKCFTIPGKAFVPKPDVDVTVVHFTPLVQPKIEQPFKLVEKVVQSVFQFRRKYCHHGIRILFPEATRLEKAE 278
*******************************9886557778999********************9999988655434 PP
>> tr|H9GIA2|H9GIA2_ANOCA rRNA adenine N(6)-methyltransferase OS=Anolis carolinensis OX=28377 GN=TFB2M PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 61.0 0.0 4.9e-20 9e-17 33 263 .. 36 312 .. 14 314 .. 0.86
Alignments for each domain:
== domain 1 score: 61.0 bits; conditional E-value: 4.9e-20
EEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHHCT....................TT CS
RrnaAD 33 tvleigpGkGilTeeLakrakqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeevte....................kd 98
v e pG+GilT+ L++ +vv+lE+ ++++ l+ + +d++l+vvh+Df + +
tr|H9GIA2|H9GIA2_ANOCA 36 LVFECEPGPGILTRTLLNAGAHVVALESNRSFLSDLESLKNkLDGQLEVVHCDFFRLDPINVG-SmkppvmysetlfenlgissvAW 121
58999***************************99999844479***************99944.3599***************9989 PP
CCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTS.TT-SHHHHHHHHHEEEEEEEEC-GG. CS
RrnaAD 99 sihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgs.kkrsrlsvlreaftdvklvakveks. 176
+++vv+ +P + ++ + + ++ g+ + l + ++ +++l+a+p + + +++lsvl ++++d++l+ + s
tr|H9GIA2|H9GIA2_ANOCA 122 TADIPLKVVGIVPQKRERNFLWKHIYalyerssIYKYGRTELNLFVSEKEYKTLIAKPKEtRIYQALSVLWQTACDIQLLHMEPWSs 208
999***********9988888777777999*9999999******************9975278*****************9999999 PP
................CECS--SSSEEEEEEEE-SS-S.--...S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT..T- CS
RrnaAD 177 ................ifsPppkvdsalvelerkdedl.pq...kdlkkyesvvrkllnrkrktlstslksllpggelqalsst.gi 242
+ + + + lv++++++ + ++ ++ + + +v+++l++ +++l +l+ l + + ++l + +i
tr|H9GIA2|H9GIA2_ANOCA 209 fltnsrngglsipksvLLQND---HLCLVRMTPRKDLFaNNltsANSSIFIVMVKQCLAKSKTKLIDKLN-LWSCESGKKLLRQlEI 291
********9887776533333...78*********98876511146677999****************88.6666666777677799 PP
-TTTCCCCSGHHHHHHHHHHH CS
RrnaAD 243 ndnalvkklsaeqtldifkel 263
+n++ + l +eq+ +f+++
tr|H9GIA2|H9GIA2_ANOCA 292 PENSTTGSLYPEQYRCLFELI 312
999999999999988777765 PP
>> tr|H9GMB0|H9GMB0_ANOCA Ribosomal RNA adenine dimethylase domain containing 1 OS=Anolis carolinensis OX=28377 GN=RRNA
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 24.4 0.0 7.4e-09 1.4e-05 26 94 .. 155 222 .. 145 235 .. 0.86
Alignments for each domain:
== domain 1 score: 24.4 bits; conditional E-value: 7.4e-09
H-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHH CS
RrnaAD 26 lnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkklskdeklkvvhqDflkfetpeev 94
++l+ ++v+++g+G+G+l++ La + v++lE d rLa k +++e l+v+++D +++ +
tr|H9GMB0|H9GMB0_ANOCA 155 SDLTGCQQVVDVGSGQGHLSRFLAFGLnLPVTALEGDARLASQAAK--FDQELLQVLKKDCNSTQVQDDF 222
5778889****************6666599************9999..88************99998865 PP
>> tr|H9GC35|H9GC35_ANOCA Methyltransferase like 22 OS=Anolis carolinensis OX=28377 GN=METTL22 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.9 0.0 2.9e-06 0.0053 22 112 .. 188 296 .. 183 353 .. 0.75
Alignments for each domain:
== domain 1 score: 15.9 bits; conditional E-value: 2.9e-06
HHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHH......HHCHTT..TCCCEEEE-S-CCGHHHHHHHCT.... CS
RrnaAD 22 IldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakl......lqkkls..kdeklkvvhqDflkfetpeevte.... 96
Il + +l ++ tvle+g G+Gi +++ ak ak v + e+L+ + l+k+++ ++k+kv D l+ ++ + +
tr|H9GC35|H9GC35_ANOCA 188 ILCNQDLFKDRTVLELGGGTGIVSVITAKAAKTVYCTDIGEDLLDMcerniaLNKHFTepAESKVKVRVLDWLQNDFCADPDNaysw 274
6777788899************************99988888876522233366777788888999988888888888765556667 PP
......TTCCCCEEEEEEE--T CS
RrnaAD 97 ......kdsihqeflvvanlPy 112
++++ +v+a + y
tr|H9GC35|H9GC35_ANOCA 275 sekeiaELHDFTTVIVAADVFY 296
7666666666666666666666 PP
>> tr|H9GDC5|H9GDC5_ANOCA tRNA methyltransferase 2 homolog A OS=Anolis carolinensis OX=28377 GN=TRMT2A PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.8 0.0 5.2e-05 0.096 16 63 .. 430 477 .. 417 497 .. 0.84
Alignments for each domain:
== domain 1 score: 11.8 bits; conditional E-value: 5.2e-05
HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HH CS
RrnaAD 16 kkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElder 63
+ ++ I d +++ +++tvl++ G+G Lak +k+v +El ++
tr|H9GDC5|H9GDC5_ANOCA 430 EVLYSAIQDWAQVGPETTVLDVCCGTGTIGITLAKKVKKVIGIELCQE 477
567888999999*******************************98665 PP
>> tr|G1KC96|G1KC96_ANOCA Protein arginine methyltransferase 9 OS=Anolis carolinensis OX=28377 GN=PRMT9 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.5 0.0 6.4e-05 0.12 18 82 .. 164 232 .. 158 253 .. 0.79
Alignments for each domain:
== domain 1 score: 11.5 bits; conditional E-value: 6.4e-05
HHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE- CS
RrnaAD 18 vineIldklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvh 82
+++++++k+ + vl+ig+G+Gil+ +ak a +v + El + +++l + l+ ++++k++h
tr|G1KC96|G1KC96_ANOCA 164 LYQKAIQKAVHSGCRSVLDIGTGTGILSM-FAKKAgaSSVYACELSKTMYELACEVLTangFSRQIKLLH 232
789999999999999************97.566665899**********999888777555556666666 PP
>> tr|H9GKF5|H9GKF5_ANOCA Protein-L-isoaspartate O-methyltransferase OS=Anolis carolinensis OX=28377 GN=LOC100554054 PE
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.7 0.0 5.5e-05 0.1 26 87 .. 74 145 .. 63 176 .. 0.84
Alignments for each domain:
== domain 1 score: 11.7 bits; conditional E-value: 5.5e-05
H-GGTTSEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHHCHTT.......TCCCEEEE-S-CCG CS
RrnaAD 26 lnleekltvleigpGkGilTeeLakra...kqvvvlElderLakllqkkls.......kdeklkvvhqDflk 87
+l e + l++g+G G lT+ +a ++ + v +E e+L+ + k+++ +++++k++ D+ k
tr|H9GKF5|H9GKF5_ANOCA 74 EQLVEGAKALDVGSGSGYLTACFARMVgptGKAVGIEHIEELVHESIKNVReddptllSSGRVKLIVGDGRK 145
456699999******************99999************9999998766666677777777777665 PP
>> tr|G1KBC8|G1KBC8_ANOCA Methyltransferase like 21C OS=Anolis carolinensis OX=28377 GN=METTL21C PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.2 0.0 7.9e-05 0.15 27 115 .. 65 156 .. 59 180 .. 0.82
Alignments for each domain:
== domain 1 score: 11.2 bits; conditional E-value: 7.9e-05
-GG.TTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHHCT..TTCCCCEEEEEEE CS
RrnaAD 27 nle.ekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkklskdeklkvvhqDflkfetpeevte..kdsihqeflvvan 109
+++ + ++vleig+G+G+ + ++a ++ v++ l e+L +l + ++ ++++v + ++ k e++ e s + +f+v+
tr|G1KBC8|G1KBC8_ANOCA 65 EISlKGKKVLEIGAGTGLVS-IVASILgAFVTATDLPEVLQNLEYNITKNTQNINVHKPEVRKLVWGENLNEdfPKSTCYNFIVATD 150
45567899*********987.7899997888888888888777777666999******99999999999988777788999999998 PP
--TTTH CS
RrnaAD 110 lPyeis 115
+ y+ +
tr|G1KBC8|G1KBC8_ANOCA 151 VVYHHT 156
888765 PP
>> tr|R4GAD1|R4GAD1_ANOCA HemK methyltransferase family member 1 OS=Anolis carolinensis OX=28377 GN=HEMK1 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.1 0.0 0.00016 0.3 33 86 .. 182 240 .. 174 251 .. 0.80
Alignments for each domain:
== domain 1 score: 10.1 bits; conditional E-value: 0.00016
EEEEES-TTTCCHHHHHCC-..SEEEEE...-S-HHHHHHHHCHTTTCCCEEEE-S-CC CS
RrnaAD 33 tvleigpGkGilTeeLakra..kqvvvl...ElderLakllqkklskdeklkvvhqDfl 86
+le+g G G+ +L+k + +v ++ E +L k+ ++l+++e++ v+h ++
tr|R4GAD1|R4GAD1_ANOCA 182 VILEVGCGSGAIALSLLKKLphSKVIAIdklEAAVNLTKENAERLNLQERVSVLHHEVS 240
69******************98888886222555667777777777********98875 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (265 nodes)
Target sequences: 18528 (9796552 residues searched)
Passed MSV filter: 585 (0.0315738); expected 370.6 (0.02)
Passed bias filter: 359 (0.0193761); expected 370.6 (0.02)
Passed Vit filter: 47 (0.0025367); expected 18.5 (0.001)
Passed Fwd filter: 10 (0.000539724); expected 0.2 (1e-05)
Initial search space (Z): 18528 [actual number of targets]
Domain search space (domZ): 10 [number of targets reported over threshold]
# CPU time: 0.19u 0.01s 00:00:00.20 Elapsed: 00:00:00.07
# Mc/sec: 37086.95
//
[ok]