# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/RrnaAD.hmm.txt
# target sequence database:        proteomes/Ciona_savignyi.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       RrnaAD  [M=265]
Accession:   PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.6e-61  207.1   0.0    2.1e-61  206.7   0.0    1.1  1  tr|H2ZDH2|H2ZDH2_CIOSA  rRNA adenine N(6)-methyltransferase O
    2.4e-39  134.4   0.0    3.1e-39  134.0   0.0    1.1  1  tr|H2YRF1|H2YRF1_CIOSA  rRNA adenine N(6)-methyltransferase O
  ------ inclusion threshold ------
      0.018   13.5   0.0      0.038   12.4   0.0    1.5  1  tr|H2Z161|H2Z161_CIOSA  Uncharacterized protein OS=Ciona savi
       0.11   11.0   0.0         30    2.9   0.0    2.9  3  tr|H2Y7Q7|H2Y7Q7_CIOSA  Uncharacterized protein OS=Ciona savi


Domain annotation for each sequence (and alignments):
>> tr|H2ZDH2|H2ZDH2_CIOSA  rRNA adenine N(6)-methyltransferase OS=Ciona savignyi OX=51511 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  206.7   0.0   7.4e-65   2.1e-61       4     227 ..      25     240 ..      23     261 .. 0.95

  Alignments for each domain:
  == domain 1  score: 206.7 bits;  conditional E-value: 7.4e-65
                             CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS
                  RrnaAD   4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87 
                             +++  gq++lkn+ +in+ ++k+ l+ ++tvleigpG+G++T ++++ +++vv+ E+d+r++++lqk++s    ++kl ++  D+lk
  tr|H2ZDH2|H2ZDH2_CIOSA  25 FNTGVGQHILKNPLIINSMVEKAALKTTDTVLEIGPGTGNMTIKILEKVNKVVACEIDPRMSAELQKRVSgtpMQRKLHLMVGDVLK 111
                             68889*****************************************************************99999************ PP

                             HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC- CS
                  RrnaAD  88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakve 174
                              +   +            +vanlPy+is+++v++ll ++r+ ++ ++l++q+efa+rl+a+pg+k+++rls+++++++ v l++kv+
  tr|H2ZDH2|H2ZDH2_CIOSA 112 LDSLPFF---------NVCVANLPYQISSPIVFKLL-LHRPLFRCAILMFQREFAQRLVAKPGEKLYCRLSINTQLLARVDLIMKVG 188
                             **99966.........49******************.899999******************************************** PP

                             GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCC CS
                  RrnaAD 175 ksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslks 227
                             k++f+Pppkv+s++v++e+++++ p  +  +++ +vr+++ rk+ktls+ + +
  tr|H2ZDH2|H2ZDH2_CIOSA 189 KNNFRPPPKVESSVVRIEPRNPP-PPINFTEWDGLVRIAFMRKNKTLSAIFRT 240
                             **********************8.899*********************98765 PP

>> tr|H2YRF1|H2YRF1_CIOSA  rRNA adenine N(6)-methyltransferase OS=Ciona savignyi OX=51511 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  134.0   0.0   1.1e-42   3.1e-39       2     239 ..      40     292 ..      39     304 .. 0.91

  Alignments for each domain:
  == domain 1  score: 134.0 bits;  conditional E-value: 1.1e-42
                             GCCXXGCG--EE--HHHHHHHHHHH-GG.TTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-C CS
                  RrnaAD   2 nklrksygqnflknkkvineIldklnle.ekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls.kdeklkvvhqDf 85 
                              ++rk+++qnfl ++ + ++ +           v e+gpG+G  T+ +++r  ++++v+E+d r++ +l+     +d +l++vh D+
  tr|H2YRF1|H2YRF1_CIOSA  40 LRARKQLSQNFLLDPMITDRFVACGGKDlSGHHVCEVGPGPGSITRAILNRNpEKLTVVEKDHRFLPMLKYLADvSDDRLQIVHGDI 126
                             578*****************998766556899********************9*****************966699*********** PP

                             CGHHHHHHHCT.....TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHH CS
                  RrnaAD  86 lkfetpeevte.....kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvl 160
                             l++++     e        +  +f v++nlP ++s +l++++l+       + + g+   +l +q+e+++r +a+pg+ +r+rlsv 
  tr|H2YRF1|H2YRF1_CIOSA 127 LQYDLSDSFPEelskeWTDDSPPFCVFGNLPFNVSLPLIFKWLDqisrkdgMFKRGRIPLVLTFQREVVERFVAPPGDAQRCRLSVS 213
                             ***97776655566566677889*************************988667778889999************************ PP

                             HHHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S.--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT CS
                  RrnaAD 161 reaftdvklvakveksifsPppkvdsalvelerkdedl.pqkdlkkyesvvrkllnrkrktlstslksllpggelqalss 239
                             ++ f+d+    ++   +f Pppkv+  +v++ +++  +  ++  k  ++vv++ +  +rk  + s k+++p ++++++s+
  tr|H2YRF1|H2YRF1_CIOSA 214 AQNFCDIDYKFIISGGSFVPPPKVEVGVVKIVPRTS-FeIELPFKTIDYVVKHTMHIRRKYCKHSVKTMFPPKRTDLVSE 292
                             ********999999999*****************99.778999******************************9998864 PP

>> tr|H2Z161|H2Z161_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   1.3e-05     0.038      18      94 ..     141     221 ..     127     257 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.3e-05
                             HHHHHHHHH-GG.TTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHH CS
                  RrnaAD  18 vineIldklnle.ekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeev 94 
                             ++++++ + +++  ++ vl++g+G Gil+   ++   ++v ++E  + +a++++k +s    ++++ v+   + +  +pe+v
  tr|H2Z161|H2Z161_CIOSA 141 TYQKAMLQNYINfRDKVVLDVGAGSGILSFFAMQAGaRKVYAVEA-STMAEHTKKLVScsqYAGRISVIPGKIEDITLPEKV 221
                             56666666666678899***********975544336*******8.78*******999887788999998877777777765 PP

>> tr|H2Y7Q7|H2Y7Q7_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0     0.038   1.1e+02     106     156 ..       3      53 ..       2      62 .. 0.86
   2 ?    2.9   0.0      0.01        30     104     147 ..     136     178 ..     117     220 .. 0.80
   3 ?    2.7   0.0     0.012        34      40      88 ..     287     337 ..     285     345 .. 0.84

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.038
                             EEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SH CS
                  RrnaAD 106 vvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsr 156
                             +v n+Pye   q +k l+ e+   + ++ l +q ++  r  +   +k++ +
  tr|H2Y7Q7|H2Y7Q7_CIOSA   3 FVNNIPYEEKWQAIKDLFREKVGEVTYVELFMQDKVKSRGYGVIEFKDKET 53 
                             799********************999********99998877777766655 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.01
                             EEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH- CS
                  RrnaAD 104 flvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrlla 147
                               +vanl y+++   vk ++++    +vk+ l+l+k    r +a
  tr|H2Y7Q7|H2Y7Q7_CIOSA 136 TVFVANLDYKVTYSKVKEVFQLAGK-VVKVDLMLDKDNKSRGMA 178
                             579*****************97766.6999****9987777665 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.012
                             TTTCCHHHH.HCC-..SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGH CS
                  RrnaAD  40 GkGilTeeL.akra..kqvvvlElderLakllqkklskdeklkvvhqDflkf 88 
                             G   l+++L ++r   +q v+ E+++rL++  +  l++  ++++  +++l+ 
  tr|H2Y7Q7|H2Y7Q7_CIOSA 287 GISDLSKQLgLNRDsyDQRVLQEQRSRLIAASRG-LTERDRIEINDNNPLQS 337
                             67778888876665579****************9.88899***999999885 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (265 nodes)
Target sequences:                        11592  (4231397 residues searched)
Passed MSV filter:                       378  (0.0326087); expected 231.8 (0.02)
Passed bias filter:                      220  (0.0189786); expected 231.8 (0.02)
Passed Vit filter:                        21  (0.00181159); expected 11.6 (0.001)
Passed Fwd filter:                         4  (0.000345066); expected 0.1 (1e-05)
Initial search space (Z):              11592  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.09u 0.00s 00:00:00.09 Elapsed: 00:00:00.03
# Mc/sec: 37377.34
//
[ok]