# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/RrnaAD.hmm.txt
# target sequence database: proteomes/Danio_rerio.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: RrnaAD [M=265]
Accession: PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.7e-65 221.2 0.0 2.1e-65 220.9 0.0 1.1 1 tr|B0S688|B0S688_DANRE rRNA adenine N(6)-methyltransfer
5.3e-42 144.2 0.0 6.4e-42 144.0 0.0 1.0 1 tr|A0A0R4IU10|A0A0R4IU10_DANRE rRNA adenine N(6)-methyltransfer
3.1e-17 63.0 0.0 4.7e-17 62.4 0.0 1.2 1 tr|B7ZVD7|B7ZVD7_DANRE rRNA adenine N(6)-methyltransfer
1.2e-08 34.9 0.0 3.4e-06 26.9 0.0 2.3 2 tr|A0A2R8QIW3|A0A2R8QIW3_DANRE Phosphoethanolamine methyltransf
0.00024 20.8 0.0 0.00039 20.1 0.0 1.3 1 tr|B3DIQ7|B3DIQ7_DANRE Methyltransferase-like 22 OS=Dan
0.0037 16.9 2.7 0.0042 16.7 2.7 1.2 1 tr|A0A0R4II97|A0A0R4II97_DANRE Stathmin OS=Danio rerio OX=7955
------ inclusion threshold ------
0.037 13.6 0.0 0.067 12.8 0.0 1.4 1 tr|A0A0R4IL77|A0A0R4IL77_DANRE Ribosomal RNA adenine dimethylas
0.054 13.1 0.1 0.11 12.0 0.0 1.5 2 tr|A0A2R8Q256|A0A2R8Q256_DANRE tRNA methyltransferase 2 homolog
0.062 12.9 0.0 0.078 12.6 0.0 1.1 1 sp|Q5D013|EFMT2_DANRE EEF1A lysine methyltransferase 2
0.21 11.1 0.0 0.34 10.4 0.0 1.3 1 sp|Q0P466|TYW2_DANRE tRNA wybutosine-synthesizing pro
Domain annotation for each sequence (and alignments):
>> tr|B0S688|B0S688_DANRE rRNA adenine N(6)-methyltransferase OS=Danio rerio OX=7955 GN=dimt1l PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 220.9 0.0 8.2e-69 2.1e-65 4 239 .. 23 249 .. 20 270 .. 0.95
Alignments for each domain:
== domain 1 score: 220.9 bits; conditional E-value: 8.2e-69
CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS
RrnaAD 4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87
+++ gq++lkn+ v+n+I++k+ l++++ vle+gpG+G++T++L++ ak+vv+ Eld+rL+++lqk+++ ++kl+++ D+lk
tr|B0S688|B0S688_DANRE 23 FNTGIGQHILKNPLVVNGIIEKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDTRLVAELQKRVQctpMQNKLQILIGDVLK 109
68899******************************************************************9999************ PP
HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC- CS
RrnaAD 88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakve 174
+e+p + +vanlPy+is+++v++ll ++r+ ++ ++l++q+efa rl+a+pg+k+++rls+++++++ v +++kv+
tr|B0S688|B0S688_DANRE 110 TELPFFD----------VCVANLPYQISSPFVFKLL-LHRPFFRCAVLMFQREFAMRLVAKPGDKLYCRLSINTQLLARVDHLMKVG 185
*****77..........7******************.788889******************************************** PP
GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT CS
RrnaAD 175 ksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalss 239
k++f+Pppkv+s++v++e+k+++ p ++ + ++ +vr++++rk+k ls+++ks ++ l+++++
tr|B0S688|B0S688_DANRE 186 KNNFRPPPKVESSVVRIEPKNPP-PPVNFQAWDGLVRIAFVRKNKMLSAAFKSAAVEKLLEKNYK 249
**********************9.899*************************9888888777755 PP
>> tr|A0A0R4IU10|A0A0R4IU10_DANRE rRNA adenine N(6)-methyltransferase OS=Danio rerio OX=7955 GN=tfb1m PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 144.0 0.0 2.5e-45 6.4e-42 2 240 .. 32 284 .. 31 309 .. 0.91
Alignments for each domain:
== domain 1 score: 144.0 bits; conditional E-value: 2.5e-45
GCCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT.TCCCE CS
RrnaAD 2 nklrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls.kdekl 78
k++k+++qnfl ++ + ++I++++ ++ v e+gpG+G lT++++k + v+E+d r++ lq + +++
tr|A0A0R4IU10|A0A0R4IU10_DANRE 32 LKAQKQLSQNFLLDTRLTDKIVRQAGNLNNAHVCEVGPGPGGLTRSILKAGaADLLVVEKDMRFIPGLQLLSEaAPGRI 110
6899*******************************************99988*****************95558889** PP
EEE-S-CCGHH....HHHHHCT.TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHH CS
RrnaAD 79 kvvhqDflkfe....tpeevte.kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrl 145
+ + D+l ++ +p ++t+ + ++ +++nlP ++st+l+ ++le fg+ + +l +qke+a+rl
tr|A0A0R4IU10|A0A0R4IU10_DANRE 111 RIAQGDILAYKlerrFPANITKtWEDDPPNLHIIGNLPFNVSTPLIIKWLEqmsnrtgIFMFGRTRLTLTFQKEVAERL 189
******988762222666777664555678**********************99998888899**************** PP
H--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCH CS
RrnaAD 146 larpgskkrsrlsvlreaftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlsts 224
+a+ gs++rsrlsv+++++t vk +++ ++f P+p+vd +v ++ +++ q+ k e++v+ ++ +rk +
tr|A0A0R4IU10|A0A0R4IU10_DANRE 190 TASTGSRQRSRLSVMAQYLTTVKSCFTIPGQAFVPKPNVDVGVVHFTPLAQPQIQQPFKLVEKIVKNAFQFRRKHCRRG 268
*************************************************997689999********************* PP
CCCTSTCHHHHHCTT. CS
RrnaAD 225 lksllpggelqalsst 240
l l+p++++q l+++
tr|A0A0R4IU10|A0A0R4IU10_DANRE 269 LGMLFPESQRQELTEE 284
***********99874 PP
>> tr|B7ZVD7|B7ZVD7_DANRE rRNA adenine N(6)-methyltransferase OS=Danio rerio OX=7955 GN=tfb2m PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 62.4 0.0 1.8e-20 4.7e-17 12 264 .. 112 414 .. 108 415 .. 0.84
Alignments for each domain:
== domain 1 score: 62.4 bits; conditional E-value: 1.8e-20
EE--HHHHHHHHHHH-GG...TTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHH CS
RrnaAD 12 flknkkvineIldklnle...ekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpee 93
f++++ ++ + d+l k + e pG+G+lT+ L++r + vv+lE+d +++ +l + s ++++l vvh+Df k + +
tr|B7ZVD7|B7ZVD7_DANRE 112 FIVDPALATIVTDHLSRDiddGKAVIFECNPGPGVLTRALLNRGaQRVVALESDANFLPELLELESrLEGQLDVVHCDFFKLDPIGN 198
777777777777777655656788899*************99987*************9999954489***************9987 PP
HCT...................TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--.TTSTT CS
RrnaAD 94 vte...................kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllar.pgskk 153
+ + ++v+ + +l+ +++ r g+v+ ++ + ++ + +l+ r + k+
tr|B7ZVD7|B7ZVD7_DANRE 199 GIMkppvmyseklfsdlaisevPWTADVPVKIVGLFTQRNERNLMWKMIYnlferrsIFRYGRVELIMFISQKEYTKLVTRpRDYKN 285
66679*********99999888777888999999999999999999888889999775556677766666555555555551678** PP
-SHHHHHHHHHEEEEEEEEC-GG...............CECS--SSSEEEEEEEE-SS-S.--...S-HHHHHHHHHHHHCTTTSBC CS
RrnaAD 154 rsrlsvlreaftdvklvakveks...............ifsPppkvdsalvelerkdedl.pq...kdlkkyesvvrkllnrkrktl 221
+++ s l+++++d++l+ + + s ++ + ++++ lv++++++ + + ++ + + +v+++l++++ +l
tr|B7ZVD7|B7ZVD7_DANRE 286 YQAFSALAQMAFDIELLHEEPLSsfltttnnnrksasgSTLSQ-SENLCLVRITPREDLFsSHltpLNGSTLVLMVKQCLAKRKGKL 371
*********************999*************965666.899**********98855422245678899************* PP
CCHCCCTSTCHHHHHCTT.T--TTTCCCCSGHHHHHHHHHHHH CS
RrnaAD 222 stslksllpggelqalsstgindnalvkklsaeqtldifkela 264
++++s pg +++s+ g d++l +++ ++++ ++f++++
tr|B7ZVD7|B7ZVD7_DANRE 372 IQQINSWSPGMGSELISNLGFLDDTLTGDVYPDEYKRLFELME 414
*********999999977799*******999999999999875 PP
>> tr|A0A2R8QIW3|A0A2R8QIW3_DANRE Phosphoethanolamine methyltransferase OS=Danio rerio OX=7955 GN=pmt PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 26.9 0.0 1.3e-09 3.4e-06 21 94 .. 42 115 .. 35 137 .. 0.87
2 ! 5.6 0.0 0.0039 9.9 19 43 .. 277 301 .. 274 377 .. 0.79
Alignments for each domain:
== domain 1 score: 26.9 bits; conditional E-value: 1.3e-09
HHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHH CS
RrnaAD 21 eIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkklskdeklkvvhqDflkfetpeev 94
eIld l + vle+g+G G T++L ra++v+++ e++++ ++ + ++ +++D+ k ++pe
tr|A0A2R8QIW3|A0A2R8QIW3_DANRE 42 EILDLLPALSESCVLELGAGIGRYTKHLIGRARHVTAVDFMEKFVEKNRQDNGHLGSVEFIQADVTKLDFPEHS 115
5666666668889*************************************877999***************954 PP
== domain 2 score: 5.6 bits; conditional E-value: 0.0039
HHHHHHHH-GGTTSEEEEES-TTTC CS
RrnaAD 19 ineIldklnleekltvleigpGkGi 43
+e +d lnl+ ++vl++g G G
tr|A0A2R8QIW3|A0A2R8QIW3_DANRE 277 TKEFVDMLNLSAGQKVLDVGCGIGG 301
57889*****************995 PP
>> tr|B3DIQ7|B3DIQ7_DANRE Methyltransferase-like 22 OS=Danio rerio OX=7955 GN=mettl22 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.1 0.0 1.5e-07 0.00039 19 124 .. 146 271 .. 139 296 .. 0.85
Alignments for each domain:
== domain 1 score: 20.1 bits; conditional E-value: 1.5e-07
HHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT........TCCCEEEE-S-CCGHHHHHHHCT. CS
RrnaAD 19 ineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls........kdeklkvvhqDflkfetpeevte. 96
++ Il ++ + + tvle+g+G+G+++ +a ak v e+L+++ q +++ +++ ++v + D + ++ ++ +
tr|B3DIQ7|B3DIQ7_DANRE 146 ADFILAQSSMFKGATVLELGAGTGLTSIVMAMVAKTVYCTDVGEDLLNMCQRNVTvnkqhfepQESEIMVRQLDWMADDFCTDA-Dl 231
56799999999*************9999999999****************9999888888888899999999999999998855.35 PP
..........TTCCCCEEEEEEE--T..TTHHHHHHHHHH CS
RrnaAD 97 ..........kdsihqeflvvanlPy..eistqlvkqlle 124
++++ f ++a + y ++ +l+ +
tr|B3DIQ7|B3DIQ7_DANRE 232 efswtdievaDLHDNTTFVIAADVCYddDLTDALFRTIYR 271
8999*****99*************9976677777766655 PP
>> tr|A0A0R4II97|A0A0R4II97_DANRE Stathmin OS=Danio rerio OX=7955 GN=stmn1a PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.7 2.7 1.6e-06 0.0042 169 262 .. 23 122 .. 1 142 [. 0.73
Alignments for each domain:
== domain 1 score: 16.7 bits; conditional E-value: 1.6e-06
EEEEC-GG......CECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTS.TCHHHHHCTT. CS
RrnaAD 169 lvakveks......ifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksll.pggelqalsst 240
+++ +++s + sPp k d++lve+++k e + ++ k e+ v k l+ kr +++l++ l ++++ ++ ++
tr|A0A0R4II97|A0A0R4II97_DANRE 23 VILGSPASdvknefLLSPPKKKDLSLVEIQKKLEAA-EERRKSHEAEVLKHLAEKREHEKEVLQKALeENNNFSKMAEE 100
33444444888888779*****************86.555555565555556666666566665554156677888888 PP
T--TTTCCCCSGHHHHHHHHHH CS
RrnaAD 241 gindnalvkklsaeqtldifke 262
++n++++++k+++ ++ ++e
tr|A0A0R4II97|A0A0R4II97_DANRE 101 KLNQKMEANKENRTAIMAAMNE 122
**********998887776665 PP
>> tr|A0A0R4IL77|A0A0R4IL77_DANRE Ribosomal RNA adenine dimethylase domain-containing 1 OS=Danio rerio OX=7955 GN=rrnad
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.8 0.0 2.6e-05 0.067 33 70 .. 158 196 .. 141 209 .. 0.83
Alignments for each domain:
== domain 1 score: 12.8 bits; conditional E-value: 2.6e-05
EEEEES-TTTCCHHHH.HCC-SEEEEE-S-HHHHHHHHC CS
RrnaAD 33 tvleigpGkGilTeeL.akrakqvvvlElderLakllqk 70
v+++g+G+G+lT+ L + +v+ +E d++L+ + +k
tr|A0A0R4IL77|A0A0R4IL77_DANRE 158 CVVDVGSGQGHLTRFLsFGLGLHVTGIEADPNLVSMATK 196
69**************66666*************99887 PP
>> tr|A0A2R8Q256|A0A2R8Q256_DANRE tRNA methyltransferase 2 homolog A OS=Danio rerio OX=7955 GN=trmt2a PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -4.2 0.1 3.9 1e+04 63 98 .. 91 126 .. 90 129 .. 0.80
2 ? 12.0 0.0 4.4e-05 0.11 25 67 .. 451 493 .. 425 508 .. 0.83
Alignments for each domain:
== domain 1 score: -4.2 bits; conditional E-value: 3.9
HHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHHCTTT CS
RrnaAD 63 rLakllqkklskdeklkvvhqDflkfetpeevtekd 98
+L k+l+k+ + +k+k++ + f t+++ +e+d
tr|A0A2R8Q256|A0A2R8Q256_DANRE 91 DLKKFLNKHGINPHKIKLLGRQKFAFVTFKNQEERD 126
577888888888999999999999999998877766 PP
== domain 2 score: 12.0 bits; conditional E-value: 4.4e-05
HH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHH CS
RrnaAD 25 klnleekltvleigpGkGilTeeLakrakqvvvlElderLakl 67
++l ++ tvl++ G+G +Lakr+k+v +El ++ +k
tr|A0A2R8Q256|A0A2R8Q256_DANRE 451 WAQLDQDSTVLDVCCGTGTIGISLAKRVKKVIGIELCQEAVKD 493
578999*****************************87776665 PP
>> sp|Q5D013|EFMT2_DANRE EEF1A lysine methyltransferase 2 OS=Danio rerio OX=7955 GN=eef1akmt2 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.6 0.0 3e-05 0.078 24 89 .. 69 137 .. 61 168 .. 0.79
Alignments for each domain:
== domain 1 score: 12.6 bits; conditional E-value: 3e-05
HHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT..TCCCEEEE-S-CCGHH CS
RrnaAD 24 dklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls..kdeklkvvhqDflkfe 89
++ n++e+ +l+ig+G G++ +eLa +++ + ++ ++l+++ l +++++ +Dfl+ +
sp|Q5D013|EFMT2_DANRE 69 EAQNISENAAILDIGTGNGMFLVELARHGfSNLTGIDYSKAALELTTNILVeeGLKNINIQVEDFLNPS 137
6789*********************76655888888877777777666554455566666666766655 PP
>> sp|Q0P466|TYW2_DANRE tRNA wybutosine-synthesizing protein 2 homolog OS=Danio rerio OX=7955 GN=trmt12 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.4 0.0 0.00013 0.34 22 92 .. 205 284 .. 187 321 .. 0.85
Alignments for each domain:
== domain 1 score: 10.4 bits; conditional E-value: 0.00013
HHHHH-GG....TTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHH CS
RrnaAD 22 Ildklnle....ekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpe 92
I +kl + tv+++++G G +T + + a +v + E ++ ++ lq +l+ +++ +v + D + ++
sp|Q0P466|TYW2_DANRE 205 ITEKLRIAsfdcSGETVVDLYAGIGYFTLPYLVHAnaAHVHACEWNPDAVAALQRNLEingVSNRCTVHQGDNRQLSLSD 284
5555555566667889************9986666569999****************99999999***999999887765 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (265 nodes)
Target sequences: 25687 (13798380 residues searched)
Passed MSV filter: 817 (0.031806); expected 513.7 (0.02)
Passed bias filter: 465 (0.0181025); expected 513.7 (0.02)
Passed Vit filter: 50 (0.00194651); expected 25.7 (0.001)
Passed Fwd filter: 10 (0.000389302); expected 0.3 (1e-05)
Initial search space (Z): 25687 [actual number of targets]
Domain search space (domZ): 10 [number of targets reported over threshold]
# CPU time: 0.26u 0.01s 00:00:00.27 Elapsed: 00:00:00.09
# Mc/sec: 40628.56
//
[ok]