# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/RrnaAD.hmm.txt
# target sequence database: proteomes/Dictyostelium_discoideum.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: RrnaAD [M=265]
Accession: PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
5.1e-64 215.4 0.0 6.2e-64 215.1 0.0 1.1 1 sp|Q54QK7|DIM1_DICDI Probable dimethyladenosine transferas
1.1e-54 184.8 0.9 2e-54 183.9 0.0 1.9 2 tr|Q54M56|Q54M56_DICDI rRNA adenine N(6)-methyltransferase O
0.00033 19.3 1.3 0.00069 18.3 1.3 1.5 1 tr|Q86K81|Q86K81_DICDI Uncharacterized protein OS=Dictyostel
0.0031 16.2 0.0 0.005 15.5 0.0 1.3 1 sp|Q55EX9|Y8948_DICDI Putative methyltransferase DDB_G02689
------ inclusion threshold ------
0.01 14.4 0.0 0.016 13.8 0.0 1.3 1 sp|Q54FP4|OMT10_DICDI O-methyltransferase 10 OS=Dictyosteli
0.011 14.3 0.0 0.012 14.2 0.0 1.1 1 tr|Q55ES6|Q55ES6_DICDI Uncharacterized protein OS=Dictyostel
0.012 14.3 0.0 0.012 14.3 0.0 1.2 1 tr|Q54LN7|Q54LN7_DICDI Uncharacterized protein OS=Dictyostel
0.013 14.1 0.0 0.019 13.5 0.0 1.3 1 tr|Q55GC0|Q55GC0_DICDI Uncharacterized protein OS=Dictyostel
0.013 14.0 0.0 0.026 13.1 0.0 1.4 1 sp|Q54XD0|COQ3_DICDI Ubiquinone biosynthesis O-methyltrans
0.019 13.5 0.0 0.032 12.8 0.0 1.3 1 tr|Q54QG2|Q54QG2_DICDI Uncharacterized protein OS=Dictyostel
Domain annotation for each sequence (and alignments):
>> sp|Q54QK7|DIM1_DICDI Probable dimethyladenosine transferase OS=Dictyostelium discoideum OX=44689 GN=dimt1 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 215.1 0.0 4.9e-67 6.2e-64 2 240 .. 27 256 .. 26 283 .. 0.92
Alignments for each domain:
== domain 1 score: 215.1 bits; conditional E-value: 4.9e-67
GCCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS
RrnaAD 2 nklrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87
++++ksygq+ lkn+ +i+ I+dk++l+ ++tvleigpG+G+lT +L++ +k+v ++E d+r+a++lqk++ ++ l+++ Dflk
sp|Q54QK7|DIM1_DICDI 27 FQMNKSYGQHLLKNPLIIDAIVDKSQLKSTDTVLEIGPGTGNLTMKLLENCKKVIAIEVDPRMAAELQKRVAaspYAQHLQIILGDFLK 115
689********************************************************************9998899*********** PP
HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GG CS
RrnaAD 88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveks 176
++p++ +van+Py+is++l ++ll +r+ +++++l++qkefa rl a+pg+++++rlsv+++++ v++++kv+k+
sp|Q54QK7|DIM1_DICDI 116 VDLPYFD----------VCVANVPYQISSPLTFKLLA-HRPIFRTAVLMFQKEFALRLGAKPGDSLYCRLSVNTQLLSKVTHLMKVGKN 193
*****77..........7******************5.88889********************************************** PP
CECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT. CS
RrnaAD 177 ifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalsst 240
+f Pppkv+sa+v++e+ +++ p + +++ +v+ ++ rk+ktls + + l+ +++t
sp|Q54QK7|DIM1_DICDI 194 NFLPPPKVESAVVRIEPFNPP-PPINFVEWDGLVKLCFSRKNKTLSGIFRVSSVIETLNQNYKT 256
********************8.799999*****************9877655555555555555 PP
>> tr|Q54M56|Q54M56_DICDI rRNA adenine N(6)-methyltransferase OS=Dictyostelium discoideum OX=44689 GN=DDB0186850 PE=3 S
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 183.9 0.0 1.6e-57 2e-54 3 263 .. 26 302 .. 24 304 .. 0.94
2 ? -2.5 0.6 1.2 1.5e+03 64 64 .. 424 424 .. 366 458 .. 0.62
Alignments for each domain:
== domain 1 score: 183.9 bits; conditional E-value: 1.6e-57
CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT..TCCCEEEE-S-CC CS
RrnaAD 3 klrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls..kdeklkvvhqDfl 86
+++++++qnfl++k++ ++I +k+ ++ tv+e+g+G+G lT++L+ k+v ++E+d+r++ l+ + +++++ ++ ++++
tr|Q54M56|Q54M56_DICDI 26 SAKQQLSQNFLIDKNITDKICKKSGGFDDCTVIEVGAGPGGLTRSLLTSGaKKVIAVEMDPRFYPALKML-EesSGGRMSLIMANMM 111
6899******************************************65544****************994.4489************ PP
GHHHHHHHCT......TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHH CS
RrnaAD 87 kfetpeevte......kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvl 160
+ + + + + + +++ + ++++nlP +++t l+ +++ ++ fg+v m+l++qke r++a+ gs ++srlsv+
tr|Q54M56|Q54M56_DICDI 112 DVDEAKLLRDagaettNWKDKSKVKIIGNLPFNVGTHLMLKWIRqiaprqgLYEFGRVPMYLMFQKELSDRICAQVGSEEYSRLSVM 198
******9999*****9999******************************************************************** PP
HHHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S...--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T--T CS
RrnaAD 161 reaftdvklvakveksifsPppkvdsalvelerkdedl...pqkdlkkyesvvrkllnrkrktlstslksllpggelqalsstgind 244
++ +++ +v+ ++ ++f Pppkvd ++v +e++ +l p+kd +e+v+r+l+ ++rk+ls+ +k+l++ +e +l + i+
tr|Q54M56|Q54M56_DICDI 199 VQQMCQPSIVYSIPGTAFVPPPKVDASVVAIEPRISPLgdePVKDHHYFEFVCRELFSQRRKKLSNTIKTLGKDAE-SLLGD-DIDP 283
**********************************9988856789*************************9998888.44445.7*** PP
TTCCCCSGHHHHHHHHHHH CS
RrnaAD 245 nalvkklsaeqtldifkel 263
+ + ++l++eq+++i +++
tr|Q54M56|Q54M56_DICDI 284 KIRTQNLQIEQFVKITNRY 302
***************9876 PP
== domain 2 score: -2.5 bits; conditional E-value: 1.2
H CS
RrnaAD 64 L 64
+
tr|Q54M56|Q54M56_DICDI 424 I 424
2 PP
>> tr|Q86K81|Q86K81_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0169088 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.3 1.3 5.4e-07 0.00069 17 98 .. 151 233 .. 133 272 .. 0.81
Alignments for each domain:
== domain 1 score: 18.3 bits; conditional E-value: 5.4e-07
HHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT..TCCCEEE.E-S-CCGHHHHHHHCTTT CS
RrnaAD 17 kvineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls..kdeklkv.vhqDflkfetpeevtekd 98
+n I ++ln++ ++++ig+G++ lT++L+ ++ +++++ e++++ k+ s +++++k ++q +++t e + +k+
tr|Q86K81|Q86K81_DICDI 151 EFVNMIAKQLNPN---EIVDIGAGEAYLTQILNHQFnHSMTAIDCSESFIEGAIKRQSliENQRIKKeLKQQKETTSTTEIINNKL 233
4566777777765...6*******************99************988777776788898887888888888888555533 PP
>> sp|Q55EX9|Y8948_DICDI Putative methyltransferase DDB_G0268948 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0268948 P
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.5 0.0 3.9e-06 0.005 30 60 .. 44 74 .. 28 93 .. 0.82
Alignments for each domain:
== domain 1 score: 15.5 bits; conditional E-value: 3.9e-06
TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S CS
RrnaAD 30 ekltvleigpGkGilTeeLakrakqvvvlEl 60
+ + ++ig+G G T++Lak++k+v +E
sp|Q55EX9|Y8948_DICDI 44 KRDLAIDIGAGSGQATVRLAKYFKKVIGFEP 74
666779********************99986 PP
>> sp|Q54FP4|OMT10_DICDI O-methyltransferase 10 OS=Dictyostelium discoideum OX=44689 GN=omt10 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.8 0.0 1.3e-05 0.016 16 96 .. 237 319 .. 227 352 .. 0.83
Alignments for each domain:
== domain 1 score: 13.8 bits; conditional E-value: 1.3e-05
HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHHCT CS
RrnaAD 16 kkvineIldklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkklskdeklkvvhqDflkfetpeevte 96
+k+ +I++ + ++ ++v +ig G G+l e+++ v vlEl e + l++ +++k ++++ l f+t + +
sp|Q54FP4|OMT10_DICDI 237 TKIHTQIINGYDFSKYKKVCDIGGGIGFLGFEIVNHNanTCVCVLELEETVRNGLEQSKVDEKKQRIIEEQRLVFKTGNMFIP 319
578899************************99965554778899**********99966689999999999999999986655 PP
>> tr|Q55ES6|Q55ES6_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB_G0268980 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.2 0.0 9.7e-06 0.012 29 55 .. 51 77 .. 36 79 .. 0.83
Alignments for each domain:
== domain 1 score: 14.2 bits; conditional E-value: 9.7e-06
GTTSEEEEES-TTTCCHHHHHCC-SEE CS
RrnaAD 29 eekltvleigpGkGilTeeLakrakqv 55
e+ + +++g+G G T++Lak++k+v
tr|Q55ES6|Q55ES6_DICDI 51 EKRDLAIDVGAGSGQATVRLAKYFKKV 77
5677789******************98 PP
>> tr|Q54LN7|Q54LN7_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB_G0286529 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.3 0.0 9.1e-06 0.012 22 55 .. 40 80 .. 9 83 .. 0.85
Alignments for each domain:
== domain 1 score: 14.3 bits; conditional E-value: 9.1e-06
HHHHH-GG.......TTSEEEEES-TTTCCHHHHHCC-SEE CS
RrnaAD 22 Ildklnle.......ekltvleigpGkGilTeeLakrakqv 55
++d++nl+ + +++l+i+ G+G lT ++++k++
tr|Q54LN7|Q54LN7_DICDI 40 AIDAINLTipkenqeKPMKILDIACGTGPLTIVANEIFKKL 80
56677777777776699**************999**99986 PP
>> tr|Q55GC0|Q55GC0_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0189501 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.5 0.0 1.5e-05 0.019 26 74 .. 41 92 .. 32 118 .. 0.83
Alignments for each domain:
== domain 1 score: 13.5 bits; conditional E-value: 1.5e-05
H-GG..TTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTTT CS
RrnaAD 26 lnle..ekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkklsk 74
++ + ++ +vl++++G+G +Te Lak +++E ++ + +k l+k
tr|Q55GC0|Q55GC0_DICDI 41 AEFKlnDNSKVLDLAAGTGKFTELLAKSKfLDITAVEPSAEFREACTKVLEK 92
554444999****************9987799*****999999988887663 PP
>> sp|Q54XD0|COQ3_DICDI Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Dictyostelium discoideum OX=44689
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.1 0.0 2e-05 0.026 17 56 .. 111 154 .. 97 200 .. 0.80
Alignments for each domain:
== domain 1 score: 13.1 bits; conditional E-value: 2e-05
HHHHHHHHHH-GG...TTSEEEEES-TTTCCHHHHHCC-.SEEE CS
RrnaAD 17 kvineIldklnle...ekltvleigpGkGilTeeLakra.kqvv 56
k++ne ++k + e l+v+++g G+G+lTe+L +vv
sp|Q54XD0|COQ3_DICDI 111 KIYNEKVSKNPIHlplEGLNVIDVGCGVGLLTESLSRLGaSKVV 154
6777777877777999*******************766545555 PP
>> tr|Q54QG2|Q54QG2_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0185725 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.8 0.0 2.5e-05 0.032 18 56 .. 189 228 .. 184 255 .. 0.81
Alignments for each domain:
== domain 1 score: 12.8 bits; conditional E-value: 2.5e-05
HHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEE CS
RrnaAD 18 vineIldklnleekltvleigpGkGilTeeLakra.kqvv 56
i + +d++nl+++ +leig G G+l e +kr v+
tr|Q54QG2|Q54QG2_DICDI 189 KIRKLIDQANLKKDHHLLEIGCGWGALAIEAVKRTgCRVT 228
57889**********************9998888765555 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (265 nodes)
Target sequences: 12739 (6856946 residues searched)
Passed MSV filter: 836 (0.0656252); expected 254.8 (0.02)
Passed bias filter: 162 (0.0127169); expected 254.8 (0.02)
Passed Vit filter: 35 (0.00274747); expected 12.7 (0.001)
Passed Fwd filter: 10 (0.000784991); expected 0.1 (1e-05)
Initial search space (Z): 12739 [actual number of targets]
Domain search space (domZ): 10 [number of targets reported over threshold]
# CPU time: 0.14u 0.01s 00:00:00.15 Elapsed: 00:00:00.05
# Mc/sec: 36341.81
//
[ok]