# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/RrnaAD.hmm.txt
# target sequence database: proteomes/Drosophila_melanogaster.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: RrnaAD [M=265]
Accession: PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.1e-64 217.7 0.1 1.5e-64 217.3 0.1 1.1 1 sp|Q9VAQ5|DIM1_DROME Probable dimethyladenosine transferas
9.9e-37 126.1 0.0 1.2e-36 125.8 0.0 1.1 1 sp|Q9VTM5|TFB1M_DROME Dimethyladenosine transferase 1, mito
3.1e-11 42.5 0.0 4.2e-11 42.0 0.0 1.2 1 sp|Q9VH38|TFB2M_DROME Dimethyladenosine transferase 2, mito
0.00081 18.2 0.0 0.0014 17.4 0.0 1.3 1 tr|Q9VVV7|Q9VVV7_DROME Uncharacterized protein OS=Drosophila
0.001 17.9 0.0 0.0015 17.3 0.0 1.3 1 tr|Q9VIF3|Q9VIF3_DROME Ubiquinone biosynthesis O-methyltrans
------ inclusion threshold ------
0.055 12.2 0.0 0.075 11.7 0.0 1.2 1 sp|Q27869|PIMT_DROME Protein-L-isoaspartate(D-aspartate) O
0.058 12.1 0.0 0.1 11.2 0.0 1.4 1 sp|Q9W1V1|ANM7_DROME Protein arginine N-methyltransferase
0.099 11.3 0.0 0.15 10.7 0.0 1.2 1 tr|Q8SX32|Q8SX32_DROME Arginine methyltransferase 8 OS=Droso
0.12 11.0 0.0 0.18 10.5 0.0 1.2 1 tr|Q9VQX9|Q9VQX9_DROME Arginine methyltransferase 2, isoform
0.14 10.8 0.0 0.23 10.1 0.0 1.2 1 sp|Q7K480|BN3D1_DROME Probable RNA methyltransferase bin3 O
Domain annotation for each sequence (and alignments):
>> sp|Q9VAQ5|DIM1_DROME Probable dimethyladenosine transferase OS=Drosophila melanogaster OX=7227 GN=CG11837 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 217.3 0.1 1.1e-67 1.5e-64 4 239 .. 23 249 .. 21 270 .. 0.94
Alignments for each domain:
== domain 1 score: 217.3 bits; conditional E-value: 1.1e-67
CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHH CS
RrnaAD 4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflkfe 89
++k++gq++lkn+ vi l+k+ l+ ++ vleigpG+G++T+++++rak+v + E+d+rLa++lqk+++ +++kl+v+ Dflk+e
sp|Q9VAQ5|DIM1_DROME 23 FNKDFGQHILKNPLVITTMLEKAALRATDVVLEIGPGTGNMTVRMLERAKKVIACEIDTRLAAELQKRVQatpLQPKLQVLIGDFLKAE 111
799*******************************************************************9999*************** PP
HHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCE CS
RrnaAD 90 tpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveksif 178
+p + l++an+Py+is++l+++ll ++r+ ++ ++l++q+efa+rl+a+pg+k+++rls+++++++ v +++kv+k++f
sp|Q9VAQ5|DIM1_DROME 112 LPFFD----------LCIANVPYQISSPLIFKLL-LHRPLFRCAVLMFQREFAERLVAKPGDKLYCRLSINTQLLARVDMLMKVGKNNF 189
***77..........9******************.899999************************************************ PP
CS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT CS
RrnaAD 179 sPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalss 239
+Pppkv+s++v+le+k+++ p ++ +++ ++r+++ rk+ktl + +k + + l+++++
sp|Q9VAQ5|DIM1_DROME 190 RPPPKVESSVVRLEPKNPP-PPVNFTEWDGLTRIAFLRKNKTLAATFKVTSVLEMLEKNYK 249
******************9.899***********************997776666666655 PP
>> sp|Q9VTM5|TFB1M_DROME Dimethyladenosine transferase 1, mitochondrial OS=Drosophila melanogaster OX=7227 GN=mtTFB1 PE
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 125.8 0.0 8.7e-40 1.2e-36 3 249 .. 31 286 .. 29 307 .. 0.87
Alignments for each domain:
== domain 1 score: 125.8 bits; conditional E-value: 8.7e-40
CCXXGCG--EE--HHHHHHHHHHH.-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT..TCCCEEE.E-.S- CS
RrnaAD 3 klrksygqnflknkkvineIldkl.nleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls..kdeklkv.vh.qD 84
++rk+++qnfl ++ + ++I++ + + + + vle+gpG+G T++++ r + + ++E+d+r+ + lq + + +++ +h D
sp|Q9VTM5|TFB1M_DROME 31 QARKQLSQNFLMDERLTDKIVKSAgRIDPRDLVLEVGPGPGGITRSILRRHpQRLLLVEKDPRFGETLQLLKEcaSPLNIQFdIHyDD 118
79*******************9984699***********************9**************9998555554444444655278 PP
CCGHHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHH.........GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHH CS
RrnaAD 85 flkfetpeevtekdsihqeflvvanlPyeistqlvkqlle.........esrfglvkmllwlqkefarrllarpgskkrsrlsvlrea 163
+l f++ + + q++ ++nlP ist l +l+ + m+l +q+e+a+r++a+ g +r+rlsv++++
sp|Q9VTM5|TFB1M_DROME 119 ILRFNIEQHI---PDTSQRIHLIGNLPFAISTRLLINWLDdlaarrgafRRI--DTCMTLTFQQEVAERICAPVGGEQRCRLSVMSQV 201
9******987...5889**************************998763333..3789****************************** PP
HEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T--TTTCCC CS
RrnaAD 164 ftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalsstgindnalvk 249
+t+ + +++ ++f P+p+vd +v+l++ + + q+ e+vvr+++ ++k + +llp + ++ + + ++ + a+v+
sp|Q9VTM5|TFB1M_DROME 202 WTEPVMKFTIPGKAFVPKPQVDVGVVKLIPLKRPKTQLPFHLVERVVRHIFSMRQKYCRRGYGTLLPPEDREEVAE-KLFQRAEVQ 286
******************************9986589999999******************999999999988866.455444444 PP
>> sp|Q9VH38|TFB2M_DROME Dimethyladenosine transferase 2, mitochondrial OS=Drosophila melanogaster OX=7227 GN=mtTFB2 PE
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 42.0 0.0 3.1e-14 4.2e-11 11 181 .. 44 245 .. 34 314 .. 0.83
Alignments for each domain:
== domain 1 score: 42.0 bits; conditional E-value: 3.1e-14
-EE--HHHHHHHHHHH-GG....TTSEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCG.HH CS
RrnaAD 11 nflknkkvineIldklnle....ekltvleigpGkGilTeeLakra...kqvvvlElderLakllqkkls.kdeklkvvhqDflk.fe 89
++ n +++I + l++ +tv+e+ +G G +T++L++r + +lE+ +++ q+ + e++kv + Df + ++
sp|Q9VH38|TFB2M_DROME 44 MYIANSEAAARINQYLEPHfqssGCDTVMELNSGAGYFTRHLLDREsqfRRIILLESMDHFMPKIQELHTlYPERVKVRQGDFVNlWK 131
57777778888888888777777789****************9987677******************7777889*********98566 PP
HHHHHCT.................TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH..--TTS CS
RrnaAD 90 tpeevte.................kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrll..arpgs 151
+ + + + + + ++lv++++ s +++k+l++ + g+ +m+l ++ ++ l+ ++ g
sp|Q9VH38|TFB2M_DROME 132 LVY-MDKmdggsrvadllsdvpqkAFTDDINMLVFGAVG---SYPFFKHLINslifqtsLFNLGRCEMILAMPPPIYIHLTcnNEIGY 215
666.44468*************99899999*******95...5566666666666686655567889*****9999887763367899 PP
TT-SHHHHHHHHHEEEEEEEEC-GGCECS- CS
RrnaAD 152 kkrsrlsvlreaftdvklvakveksifsPp 181
++++svl +++++ k++akv+++ f P+
sp|Q9VH38|TFB2M_DROME 216 LIYRSTSVLFQILFEHKFIAKVPREDFLPQ 245
9************************88776 PP
>> tr|Q9VVV7|Q9VVV7_DROME Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=cg3808 PE=1 SV=3
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.4 0.0 1e-06 0.0014 17 60 .. 402 445 .. 392 460 .. 0.91
Alignments for each domain:
== domain 1 score: 17.4 bits; conditional E-value: 1e-06
HHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S CS
RrnaAD 17 kvineIldklnleekltvleigpGkGilTeeLakrakqvvvlEl 60
++++++d + +++++t+l+i G+G T +ak +k+v +E+
tr|Q9VVV7|Q9VVV7_DROME 402 VLYQKAIDLVAPTKDTTMLDICCGTGTITLAFAKHCKKVMGVEI 445
6899***********************************99997 PP
>> tr|Q9VIF3|Q9VIF3_DROME Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Drosophila melanogaster OX=7227
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.3 0.0 1.1e-06 0.0015 25 74 .. 90 140 .. 76 181 .. 0.86
Alignments for each domain:
== domain 1 score: 17.3 bits; conditional E-value: 1.1e-06
HH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT.T CS
RrnaAD 25 klnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls.k 74
++++ +++le+g G G+lTe+La qv + l e+L++ +++l+ +
tr|Q9VIF3|Q9VIF3_DROME 90 TTKVLLGQNILEVGCGGGLLTEHLARLGAQVAGIDLGEKLIEAAREHLKcS 140
555666799**************************************9953 PP
>> sp|Q27869|PIMT_DROME Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Drosophila melanogaster OX=7227 GN=P
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.7 0.0 5.4e-05 0.075 28 74 .. 76 137 .. 69 178 .. 0.77
Alignments for each domain:
== domain 1 score: 11.7 bits; conditional E-value: 5.4e-05
GGTTSEEEEES-TTTCCHHHHHCC-........SEEEEE-S-HHHHHHHHCHTT.......T CS
RrnaAD 28 leekltvleigpGkGilTeeLakra........kqvvvlElderLakllqkkls.......k 74
l++ +l++g+G G lT+ + ++ v +E +L+ + +++l+ +
sp|Q27869|PIMT_DROME 76 LKPGARILDVGSGSGYLTACFYRYIkakgvdadTRIVGIEHQAELVRRSKANLNtddrsmlD 137
678899***************99996655555556799999999999999999944444444 PP
>> sp|Q9W1V1|ANM7_DROME Protein arginine N-methyltransferase 7 OS=Drosophila melanogaster OX=7227 GN=Art7 PE=2 SV=4
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.2 0.0 7.6e-05 0.1 31 94 .. 65 132 .. 49 166 .. 0.82
Alignments for each domain:
== domain 1 score: 11.2 bits; conditional E-value: 7.6e-05
TSEEEEES-TTTCCHH.HHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHH CS
RrnaAD 31 kltvleigpGkGilTe.eLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeev 94
+ vl+ig+G+Gil+ La a++v++ E +a+ +k l + k+ ++ + + ++ e++
sp|Q9W1V1|ANM7_DROME 65 EVHVLDIGTGTGILSMmALAAGADSVTACEAFLPMANCAEKILAangAGDKVRLIRKRSTEIQVGEDM 132
678************72568889********9999999999777777788888888888888888866 PP
>> tr|Q8SX32|Q8SX32_DROME Arginine methyltransferase 8 OS=Drosophila melanogaster OX=7227 GN=Art8 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.7 0.0 0.00011 0.15 18 73 .. 28 84 .. 24 123 .. 0.76
Alignments for each domain:
== domain 1 score: 10.7 bits; conditional E-value: 0.00011
HHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT CS
RrnaAD 18 vineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls 73
+n Il + +l +++ v+++g+G+Gil++ ak + v ++E ++ k+ + ++
tr|Q8SX32|Q8SX32_DROME 28 YYNAILGNKDLFKDKIVMDVGAGTGILSAFCAKAGaRLVYAVEASNVATKVALDLIE 84
6899************************99998876888888877666666555555 PP
>> tr|Q9VQX9|Q9VQX9_DROME Arginine methyltransferase 2, isoform A OS=Drosophila melanogaster OX=7227 GN=Art2 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.5 0.0 0.00013 0.18 18 92 .. 55 132 .. 48 157 .. 0.78
Alignments for each domain:
== domain 1 score: 10.5 bits; conditional E-value: 0.00013
HHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHH CS
RrnaAD 18 vineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpe 92
+ e++++ + +tvl++g G G+l+ ak k v ++E ++++ q+ ++ ++ ++v++ + + e+p
tr|Q9VQX9|Q9VQX9_DROME 55 AYREAIQHNEFFRHKTVLDVGCGMGVLSMFAAKAGsKRVLAVEAA-TISEFAQQVVQdneFGRVIQVIQGKVEDIELPD 132
57789999999999**************99999888999999975.344444444443326677777777776666665 PP
>> sp|Q7K480|BN3D1_DROME Probable RNA methyltransferase bin3 OS=Drosophila melanogaster OX=7227 GN=bin3 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.1 0.0 0.00017 0.23 24 73 .. 814 865 .. 807 885 .. 0.88
Alignments for each domain:
== domain 1 score: 10.1 bits; conditional E-value: 0.00017
HHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT CS
RrnaAD 24 dklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls 73
++++l e++ +l+ig +G++T +a + k v + +d++L+++ + +ls
sp|Q7K480|BN3D1_DROME 814 RHVELFENKDILDIGCNVGHMTITVARHLapKTIVGIDIDRELVARARRNLS 865
578889*******************98888***************9998776 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (265 nodes)
Target sequences: 13786 (7394964 residues searched)
Passed MSV filter: 394 (0.0285797); expected 275.7 (0.02)
Passed bias filter: 235 (0.0170463); expected 275.7 (0.02)
Passed Vit filter: 29 (0.00210358); expected 13.8 (0.001)
Passed Fwd filter: 10 (0.000725374); expected 0.1 (1e-05)
Initial search space (Z): 13786 [actual number of targets]
Domain search space (domZ): 10 [number of targets reported over threshold]
# CPU time: 0.15u 0.01s 00:00:00.16 Elapsed: 00:00:00.06
# Mc/sec: 32661.09
//
[ok]