# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/RrnaAD.hmm.txt # target sequence database: proteomes/Homo_sapiens.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: RrnaAD [M=265] Accession: PF00398.19 Description: Ribosomal RNA adenine dimethylase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.1e-65 222.7 0.0 2.5e-65 222.4 0.0 1.1 1 sp|Q9UNQ2|DIM1_HUMAN Probable dimethyladenosine transferas 8.9e-42 145.2 0.0 1.1e-41 145.0 0.0 1.1 1 sp|Q8WVM0|TFB1M_HUMAN Dimethyladenosine transferase 1, mito 5.5e-31 109.9 0.0 6.3e-31 109.7 0.0 1.0 1 tr|D6RCL3|D6RCL3_HUMAN Probable dimethyladenosine transferas 2.5e-19 71.7 0.0 4.1e-19 70.9 0.0 1.3 1 sp|Q9H5Q4|TFB2M_HUMAN Dimethyladenosine transferase 2, mito 1.5e-05 26.5 0.0 1.7e-05 26.3 0.0 1.1 1 tr|F5H7M4|F5H7M4_HUMAN Dimethyladenosine transferase 2, mito 0.0025 19.2 0.0 0.0066 17.8 0.0 1.6 1 tr|B3KU92|B3KU92_HUMAN Putative protein arginine N-methyltra 0.0033 18.8 0.0 0.0081 17.5 0.0 1.6 1 sp|Q6P2P2|ANM10_HUMAN Putative protein arginine N-methyltra ------ inclusion threshold ------ 0.032 15.6 0.0 0.05 14.9 0.0 1.3 1 tr|E5RJL6|E5RJL6_HUMAN Protein RRNAD1 (Fragment) OS=Homo sap 0.039 15.3 0.0 0.054 14.8 0.0 1.3 1 tr|H0YBL9|H0YBL9_HUMAN Protein RRNAD1 (Fragment) OS=Homo sap 0.051 14.9 0.0 0.07 14.5 0.0 1.3 1 tr|F8WDR2|F8WDR2_HUMAN tRNA (adenine(58)-N(1))-methyltransfe 0.073 14.4 0.0 0.12 13.6 0.0 1.3 1 sp|Q9BVS5|TR61B_HUMAN tRNA (adenine(58)-N(1))-methyltransfe 0.18 13.1 0.0 0.27 12.6 0.0 1.2 1 tr|Q4VX71|Q4VX71_HUMAN Protein RRNAD1 OS=Homo sapiens GN=RRN 0.33 12.3 0.0 0.51 11.6 0.0 1.2 1 sp|Q96FB5|RRNAD_HUMAN Protein RRNAD1 OS=Homo sapiens GN=RRN 0.43 11.9 0.0 1.9 9.8 0.0 1.8 2 tr|H3BN86|H3BN86_HUMAN Methyltransferase-like protein 9 (Fra 0.46 11.8 0.0 0.55 11.5 0.0 1.1 1 tr|H3BM54|H3BM54_HUMAN Methyltransferase-like protein 9 (Fra 0.75 11.1 0.0 0.92 10.8 0.0 1.1 1 tr|H3BQD2|H3BQD2_HUMAN Methyltransferase-like protein 9 (Fra 0.84 10.9 0.0 1.1 10.5 0.0 1.1 1 sp|O60344-4|ECE2_HUMAN Isoform D of Endothelin-converting en Domain annotation for each sequence (and alignments): >> sp|Q9UNQ2|DIM1_HUMAN Probable dimethyladenosine transferase OS=Homo sapiens GN=DIMT1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 222.4 0.0 4.9e-69 2.5e-65 4 237 .. 30 254 .. 27 274 .. 0.96 Alignments for each domain: == domain 1 score: 222.4 bits; conditional E-value: 4.9e-69 CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHH CS RrnaAD 4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflkfe 89 +++ gq++lkn+ +in+I+dk+ l++++ vle+gpG+G++T++L++ ak+vv+ Eld+rL+++l k+++ ++kl+v+ D+lk++ sp|Q9UNQ2|DIM1_HUMAN 30 FNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQgtpVASKLQVLVGDVLKTD 118 78999*****************************************************************9999*************** PP HHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCE CS RrnaAD 90 tpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveksif 178 +p + +vanlPy+is+++v++ll ++r+ ++ ++l++q+efa rl+a+pg+k+++rls+++++++ v +++kv+k++f sp|Q9UNQ2|DIM1_HUMAN 119 LPFFD----------TCVANLPYQISSPFVFKLL-LHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNF 196 ***88..........6******************.788889************************************************ PP CS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHC CS RrnaAD 179 sPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqal 237 +Pppkv+s++v++e+k+++ p + ++++ +vr+ ++rk+ktls+++ks ++ l+++ sp|Q9UNQ2|DIM1_HUMAN 197 RPPPKVESSVVRIEPKNPP-PPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKN 254 ******************8.89**************************98888877766 PP >> sp|Q8WVM0|TFB1M_HUMAN Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens GN=TFB1M PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 145.0 0.0 2.1e-45 1.1e-41 3 244 .. 28 282 .. 26 303 .. 0.89 Alignments for each domain: == domain 1 score: 145.0 bits; conditional E-value: 2.1e-45 CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT..TCCCEEEE-S-CCG CS RrnaAD 3 klrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls..kdeklkvvhqDflk 87 ++ k+++qnfl + + ++I++k+ + v+e+gpG+G T+++++ ++ v+E+d+r++ lq ls +kl +vh D+l+ sp|Q8WVM0|TFB1M_HUMAN 28 QAAKQLSQNFLLDLRLTDKIVRKAGNLTNAYVYEVGPGPGGITRSILNADvAELLVVEKDTRFIPGLQM-LSdaAPGKLRIVHGDVLT 114 56789*******************99999***************9966655******************.5558889*********** PP HHHHHHHCT.....TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHH CS RrnaAD 88 fetpeevte.....kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlrea 163 f++ + e + + +++nlP +st+l+ ++le g+ +m+l +qke+a+rl+a+ gsk+rsrlsv++++ sp|Q8WVM0|TFB1M_HUMAN 115 FKVEKAFSEslkrpWEDDPPNVHIIGNLPFSVSTPLIIKWLEniscrdgPFVYGRTQMTLTFQKEVAERLAANTGSKQRSRLSVMAQY 202 *****998888887555667899*********************999885566789******************************** PP HEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T--T CS RrnaAD 164 ftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalsstgind 244 +++v+++ +++ ++f P+p+vd +v ++ ++ ++ k e+vv+ ++ +rk l l+p++++ + ++ + sp|Q8WVM0|TFB1M_HUMAN 203 LCNVRHIFTIPGQAFVPKPEVDVGVVHFTPLIQPKIEQPFKLVEKVVQNVFQFRRKYCHRGLRMLFPEAQRLESTG-RLLE 282 *****************************97665347788999**************************9876644.4554 PP >> tr|D6RCL3|D6RCL3_HUMAN Probable dimethyladenosine transferase OS=Homo sapiens GN=DIMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 109.7 0.0 1.2e-34 6.3e-31 4 127 .. 30 145 .. 27 152 .. 0.94 Alignments for each domain: == domain 1 score: 109.7 bits; conditional E-value: 1.2e-34 CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS RrnaAD 4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87 +++ gq++lkn+ +in+I+dk+ l++++ vle+gpG+G++T++L++ ak+vv+ Eld+rL+++l k+++ ++kl+v+ D+lk tr|D6RCL3|D6RCL3_HUMAN 30 FNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQgtpVASKLQVLVGDVLK 116 78999*****************************************************************9999************* PP HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGG CS RrnaAD 88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesr 127 +++p + +vanlPy+is+++v++ll ++r tr|D6RCL3|D6RCL3_HUMAN 117 TDLPFFD----------TCVANLPYQISSPFVFKLL-LHR 145 *****88..........6*****************9.444 PP >> sp|Q9H5Q4|TFB2M_HUMAN Dimethyladenosine transferase 2, mitochondrial OS=Homo sapiens GN=TFB2M PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 70.9 0.0 7.9e-23 4.1e-19 30 263 .. 95 377 .. 71 379 .. 0.87 Alignments for each domain: == domain 1 score: 70.9 bits; conditional E-value: 7.9e-23 TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHHCT.................... CS RrnaAD 30 ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeevte.................... 96 + +le pG+GilT+ L++ +vv+lE+d+ ++ +l+ + +d+kl v+h+Df k + + + sp|Q9H5Q4|TFB2M_HUMAN 95 PPHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKnLDGKLRVIHCDFFKLDPRSGG-Vikppamssrglfknlgieav 181 566789**********************************97669*****************9943.2469**************999 PP TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTS.TT-SHHHHHHHHHEEEEEEEEC-GG CS RrnaAD 97 kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgs.kkrsrlsvlreaftdvklvakveks 176 +++vv+ P + +l ++fg+ ++ + + ++ ++l+a+pg+ ++ lsv+ ++++++k++ + s sp|Q9H5Q4|TFB2M_HUMAN 182 PWTADIPLKVVGMFPSRGEKRALWKLAYdlysctsIYKFGRIEVNMFIGEKEFQKLMADPGNpDLYHVLSVIWQLACEIKVLHMEPWS 269 888999*********966555444444458889999***********999999*******98468*****************999999 PP ..................CECS--SSSEEEEEEEE-SS-S.--S...-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T- CS RrnaAD 177 ..................ifsPppkvdsalvelerkdedl.pqk...dlkkyesvvrkllnrkrktlstslksllpggelqalsstgi 242 + + + ++ l++++++++ + +++ +++ + ++++++ r++ t+ l sl+p ++++ l + g sp|Q9H5Q4|TFB2M_HUMAN 270 sfdiytrkgplenpkrreL-LDQLQQKLYLIQMIPRQNLFtKNLtpmNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGK 356 9**************9953.7788899***********99776533378888999**************************9987799 PP -TTTCCCCSGHHHHHHHHHHH CS RrnaAD 243 ndnalvkklsaeqtldifkel 263 +++ +v++ ++++ ++f+ + sp|Q9H5Q4|TFB2M_HUMAN 357 QEDEKVVNMHPQDFKTLFETI 377 999*************99987 PP >> tr|F5H7M4|F5H7M4_HUMAN Dimethyladenosine transferase 2, mitochondrial OS=Homo sapiens GN=TFB2M PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.3 0.0 3.3e-09 1.7e-05 24 70 .. 85 135 .. 66 137 .] 0.81 Alignments for each domain: == domain 1 score: 26.3 bits; conditional E-value: 3.3e-09 HHH-GG....TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHC CS RrnaAD 24 dklnle....ekltvleigpGkGilTeeLakrakqvvvlElderLakllqk 70 +++l + +le pG+GilT+ L++ +vv+lE+d+ ++ +l++ tr|F5H7M4|F5H7M4_HUMAN 85 AQIYLGkpsrPPHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLET 135 555555555566779********************************9987 PP >> tr|B3KU92|B3KU92_HUMAN Putative protein arginine N-methyltransferase 10 OS=Homo sapiens GN=LOC90826 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 1.3e-06 0.0066 16 94 .. 50 132 .. 44 157 .. 0.87 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 1.3e-06 HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHH CS RrnaAD 16 kkvineIldklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeev 94 ++++n +++k+ ++ vl+ig+G+Gil+ +ak a +v + El + +++l + + + +k++h+ l+ e+p+ + tr|B3KU92|B3KU92_HUMAN 50 NTIYNAAIQKAVCLGSKSVLDIGAGTGILSM-FAKKAgaHSVYACELSKTMYELACDVVAankMEAGIKLLHTKSLDIEIPKHI 132 6799*************************97.56666589999**********9999877776788899999999999999966 PP >> sp|Q6P2P2|ANM10_HUMAN Putative protein arginine N-methyltransferase 10 OS=Homo sapiens GN=PRMT10 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 1.6e-06 0.0081 16 94 .. 163 245 .. 157 269 .. 0.87 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 1.6e-06 HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHH CS RrnaAD 16 kkvineIldklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeev 94 ++++n +++k+ ++ vl+ig+G+Gil+ +ak a +v + El + +++l + + + +k++h+ l+ e+p+ + sp|Q6P2P2|ANM10_HUMAN 163 NTIYNAAIQKAVCLGSKSVLDIGAGTGILSM-FAKKAgaHSVYACELSKTMYELACDVVAankMEAGIKLLHTKSLDIEIPKHI 245 6799*************************97.56666589999**********9999877776788899999999999999965 PP >> tr|E5RJL6|E5RJL6_HUMAN Protein RRNAD1 (Fragment) OS=Homo sapiens GN=RRNAD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.9 0.0 9.6e-06 0.05 31 70 .. 52 92 .. 39 99 .. 0.86 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 9.6e-06 TSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHC CS RrnaAD 31 kltvleigpGkGilTeeLakra.kqvvvlElderLakllqk 70 ++v+++g+G+G+l++ +a + v ++E d+rL+++ q tr|E5RJL6|E5RJL6_HUMAN 52 CTQVVDVGSGQGHLSRFMALGLgLMVKSIEGDQRLVERAQR 92 579***************888879999**********9987 PP >> tr|H0YBL9|H0YBL9_HUMAN Protein RRNAD1 (Fragment) OS=Homo sapiens GN=RRNAD1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.8 0.0 1e-05 0.054 31 70 .. 41 81 .. 28 108 .. 0.84 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 1e-05 TSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHC CS RrnaAD 31 kltvleigpGkGilTeeLakra.kqvvvlElderLakllqk 70 ++v+++g+G+G+l++ +a + v ++E d+rL+++ q tr|H0YBL9|H0YBL9_HUMAN 41 CTQVVDVGSGQGHLSRFMALGLgLMVKSIEGDQRLVERAQR 81 579***************888879999**********9997 PP >> tr|F8WDR2|F8WDR2_HUMAN tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial OS=Homo sapiens GN=TRMT61B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.0 1.3e-05 0.07 16 69 .. 232 288 .. 192 320 .. 0.87 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 1.3e-05 HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHH CS RrnaAD 16 kkvineIldklnleekltvleigpGkGilTeeLakra...kqvvvlElderLakllq 69 +k in Il+ +++++ +tvle g+G G ++ L k + v ++E +++ l + tr|F8WDR2|F8WDR2_HUMAN 232 PKDINMILSMMDINPGDTVLEAGSGSGGMSLFLSKAVgsqGRVISFEVRKDHHDLAK 288 56799****************************999987777899998876444444 PP >> sp|Q9BVS5|TR61B_HUMAN tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial OS=Homo sapiens GN=TRMT61B PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 2.4e-05 0.12 17 69 .. 233 288 .. 229 319 .. 0.82 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 2.4e-05 HHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHH CS RrnaAD 17 kvineIldklnleekltvleigpGkGilTeeLakra...kqvvvlElderLakllq 69 k in Il+ +++++ +tvle g+G G ++ L k + v ++E +++ l + sp|Q9BVS5|TR61B_HUMAN 233 KDINMILSMMDINPGDTVLEAGSGSGGMSLFLSKAVgsqGRVISFEVRKDHHDLAK 288 6699****************************999987777899998876444444 PP >> tr|Q4VX71|Q4VX71_HUMAN Protein RRNAD1 OS=Homo sapiens GN=RRNAD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 5.1e-05 0.27 32 70 .. 155 194 .. 141 206 .. 0.85 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 5.1e-05 SEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHC CS RrnaAD 32 ltvleigpGkGilTeeLakra.kqvvvlElderLakllqk 70 ++v+++g+G+G+l++ +a + v ++E d+rL+++ q tr|Q4VX71|Q4VX71_HUMAN 155 TQVVDVGSGQGHLSRFMALGLgLMVKSIEGDQRLVERAQR 194 79***************888879999**********9997 PP >> sp|Q96FB5|RRNAD_HUMAN Protein RRNAD1 OS=Homo sapiens GN=RRNAD1 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 9.8e-05 0.51 32 70 .. 155 194 .. 143 218 .. 0.85 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 9.8e-05 SEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHC CS RrnaAD 32 ltvleigpGkGilTeeLakra.kqvvvlElderLakllqk 70 ++v+++g+G+G+l++ +a + v ++E d+rL+++ q sp|Q96FB5|RRNAD_HUMAN 155 TQVVDVGSGQGHLSRFMALGLgLMVKSIEGDQRLVERAQR 194 79***************888879999**********9997 PP >> tr|H3BN86|H3BN86_HUMAN Methyltransferase-like protein 9 (Fragment) OS=Homo sapiens GN=METTL9 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.0 0.6 3.1e+03 208 237 .. 11 40 .. 2 54 .. 0.67 2 ? 9.8 0.0 0.00036 1.9 25 71 .. 99 146 .. 83 163 .. 0.85 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 0.6 HHHHHHHCTTTSBCCCHCCCTSTCHHHHHC CS RrnaAD 208 svvrkllnrkrktlstslksllpggelqal 237 ++ +k+ ++ r +l +sl+ ++ ++ l+ tr|H3BN86|H3BN86_HUMAN 11 KFYEKWYVCNREKLCESLQAVFVQSYLDQG 40 577788888888888888877777766555 PP == domain 2 score: 9.8 bits; conditional E-value: 0.00036 HH-GG.TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCH CS RrnaAD 25 klnle.ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkk 71 k+n+ ++ +l++g+G G T+++ +++ + El e ++ lqkk tr|H3BN86|H3BN86_HUMAN 99 KINPDwKTHRLLDLGAGDGEVTKIMSPHFEEIYATELSETMIWQLQKK 146 6788889999*********************************99994 PP >> tr|H3BM54|H3BM54_HUMAN Methyltransferase-like protein 9 (Fragment) OS=Homo sapiens GN=METTL9 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.5 0.0 0.00011 0.55 24 71 .. 27 75 .. 12 96 .. 0.84 Alignments for each domain: == domain 1 score: 11.5 bits; conditional E-value: 0.00011 HHH-GG.TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCH CS RrnaAD 24 dklnle.ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkk 71 k+n+ ++ +l++g+G G T+++ +++ + El e ++ lqkk tr|H3BM54|H3BM54_HUMAN 27 LKINPDwKTHRLLDLGAGDGEVTKIMSPHFEEIYATELSETMIWQLQKK 75 36788889999**********************************9994 PP >> tr|H3BQD2|H3BQD2_HUMAN Methyltransferase-like protein 9 (Fragment) OS=Homo sapiens GN=METTL9 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00018 0.92 25 71 .. 10 57 .. 6 78 .. 0.89 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00018 HH-GG.TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCH CS RrnaAD 25 klnle.ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkk 71 k+n+ ++ +l++g+G G T+++ +++ + El e ++ lqkk tr|H3BQD2|H3BQD2_HUMAN 10 KINPDwKTHRLLDLGAGDGEVTKIMSPHFEEIYATELSETMIWQLQKK 57 6677778999**********************************9994 PP >> sp|O60344-4|ECE2_HUMAN Isoform D of Endothelin-converting enzyme 2 OS=Homo sapiens GN=ECE2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 0.00022 1.1 26 93 .. 54 122 .. 49 149 .. 0.90 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.00022 H-GGTTSEEEEES-TTTCCHHHH.HCC-SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHH CS RrnaAD 26 lnleekltvleigpGkGilTeeL.akrakqvvvlElderLakllqkklskdeklkvvhqDflkfetpee 93 +l++++ +l +g G +l+ eL + + +v+++ ++ ++ +q++ ++l + D+ k ++p+ sp|O60344-4|ECE2_HUMAN 54 PELRPEDRILVLGCGNSALSYELfLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPSA 122 5799*******************77788******************999*****************995 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 88473 (35070517 residues searched) Passed MSV filter: 2361 (0.0266861); expected 1769.5 (0.02) Passed bias filter: 1556 (0.0175873); expected 1769.5 (0.02) Passed Vit filter: 181 (0.00204582); expected 88.5 (0.001) Passed Fwd filter: 17 (0.000192149); expected 0.9 (1e-05) Initial search space (Z): 88473 [actual number of targets] Domain search space (domZ): 17 [number of targets reported over threshold] # CPU time: 0.70u 0.03s 00:00:00.73 Elapsed: 00:00:00.25 # Mc/sec: 37174.75 // [ok]