# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/RrnaAD.hmm.txt
# target sequence database:        proteomes/Macaca_mulatta.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       RrnaAD  [M=265]
Accession:   PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence                       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------                       -----------
      5e-66  222.7   0.0    6.1e-66  222.4   0.0    1.1  1  tr|F6X5A5|F6X5A5_MACMU          rRNA adenine N(6)-methyltransfer
    1.9e-42  145.4   0.0    2.4e-42  145.1   0.0    1.1  1  tr|F6VAH2|F6VAH2_MACMU          rRNA adenine N(6)-methyltransfer
    4.6e-17   62.2   0.0      9e-17   61.2   0.0    1.4  1  tr|F6W6K7|F6W6K7_MACMU          rRNA adenine N(6)-methyltransfer
    1.5e-10   40.8   0.0    1.4e-07   31.1   0.0    2.1  2  tr|A0A1D5QK90|A0A1D5QK90_MACMU  rRNA adenine N(6)-methyltransfer
     0.0033   16.8   0.0     0.0072   15.7   0.0    1.5  1  tr|G7MS35|G7MS35_MACMU          Protein arginine methyltransfera
  ------ inclusion threshold ------
      0.078   12.3   0.0       0.12   11.6   0.0    1.2  1  tr|F6UBC5|F6UBC5_MACMU          Protein RRNAD1 isoform 1 OS=Maca
       0.18   11.1   0.0       0.39   10.0   0.0    1.5  1  tr|F7D1K5|F7D1K5_MACMU          tRNA methyltransferase 61B OS=Ma


Domain annotation for each sequence (and alignments):
>> tr|F6X5A5|F6X5A5_MACMU  rRNA adenine N(6)-methyltransferase OS=Macaca mulatta OX=9544 GN=DIMT1 PE=3 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  222.4   0.0     2e-69   6.1e-66       4     237 ..      30     254 ..      27     274 .. 0.96

  Alignments for each domain:
  == domain 1  score: 222.4 bits;  conditional E-value: 2e-69
                             CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS
                  RrnaAD   4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87 
                             +++  gq++lkn+ +in+I+dk+ l++++ vle+gpG+G++T++L++ ak+vv+ Eld+rL+++l k+++    ++kl+v+  D+lk
  tr|F6X5A5|F6X5A5_MACMU  30 FNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQgtpVASKLQVLVGDVLK 116
                             78999*****************************************************************9999************* PP

                             HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC- CS
                  RrnaAD  88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakve 174
                             +++p +            +vanlPy+is+++v++ll ++r+ ++ ++l++q+efa rl+a+pg+k+++rls+++++++ v +++kv+
  tr|F6X5A5|F6X5A5_MACMU 117 TDLPFFD----------TCVANLPYQISSPFVFKLL-LHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVG 192
                             *****88..........6******************.788889******************************************** PP

                             GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHC CS
                  RrnaAD 175 ksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqal 237
                             k++f+Pppkv+s++v++e+k+++ p  + ++++ +vr+ ++rk+ktls+++ks   ++ l+++
  tr|F6X5A5|F6X5A5_MACMU 193 KNNFRPPPKVESSVVRIEPKNPP-PPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKN 254
                             **********************8.89**************************98888877766 PP

>> tr|F6VAH2|F6VAH2_MACMU  rRNA adenine N(6)-methyltransferase OS=Macaca mulatta OX=9544 GN=TFB1M PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.1   0.0     8e-46   2.4e-42       3     243 ..      28     281 ..      26     302 .. 0.90

  Alignments for each domain:
  == domain 1  score: 145.1 bits;  conditional E-value: 8e-46
                             CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCG CS
                  RrnaAD   3 klrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls.kdeklkvvhqDflk 87 
                             ++ k+++qnfl +  + ++I++k+    +  v+e+gpG+G  T+++++    ++ v+E+d+r++  lq   +   +kl +vh D+l+
  tr|F6VAH2|F6VAH2_MACMU  28 QATKQLSQNFLLDLRLTDKIVRKAGNLANAYVYEVGPGPGGITRSILNADvAELLVVEKDTRFIPGLQMLSEaAPGKLRIVHGDVLT 114
                             67799***************************************9966655******************6558889*********** PP

                             HHHHHHHCT.....TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHH CS
                  RrnaAD  88 fetpeevte.....kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlre 162
                             f++ +   e        +  +  +++nlP  +st+l+ ++le           g+ +m+l +qke+a+rl+a+ gsk+rsrlsv+++
  tr|F6VAH2|F6VAH2_MACMU 115 FKVEKAFSEslkrpWEDDPPNVHIIGNLPFSVSTPLIIKWLEniscrdgPFVYGRTQMTLTFQKEVAERLAANTGSKQRSRLSVMAQ 201
                             *****998888887555667899*********************999885566789******************************* PP

                             HHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T-- CS
                  RrnaAD 163 aftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalsstgin 243
                             ++++v+++ +++ ++f P+p+vd  +v  ++  ++  ++  k  e+vv+ ++  +rk     l  l+p++++  ++  ++ 
  tr|F6VAH2|F6VAH2_MACMU 202 YLCNVRHIFTIPGRAFVPKPEVDVGVVHFTPLIQPKIEQPFKLVEKVVQNVFQFRRKYCHRGLGMLFPEAQRLENTG-RLL 281
                             ******************************97665347788999**************************9887754.444 PP

>> tr|F6W6K7|F6W6K7_MACMU  rRNA adenine N(6)-methyltransferase OS=Macaca mulatta OX=9544 GN=TFB2M PE=3 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.2   0.0     3e-20     9e-17      32     263 ..      97     377 ..      80     379 .. 0.83

  Alignments for each domain:
  == domain 1  score: 61.2 bits;  conditional E-value: 3e-20
                             SEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHHCT...................TT CS
                  RrnaAD  32 ltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeevte...................kd 98 
                               +le  pG+GilTe L++    vv+lE+d+ ++ +l+   + +d+kl v+h+Df   +  +                         
  tr|F6W6K7|F6W6K7_MACMU  97 HLLLECNPGPGILTEALLEAGATVVALESDKTFIPHLESLGKnLDGKLRVIHCDFFRIDPRSGGAIkppamsseglfknlgveevPW 183
                             5689**********************************97669*****************99433379*997777777777777766 PP

                             CCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--T.TSTT-SHHHHHHHHHEEEEEEEEC-GG. CS
                  RrnaAD  99 sihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarp.gskkrsrlsvlreaftdvklvakveks. 176
                               + +++v++  P    +    +l          ++fg+ ++ + + ++  ++l+a+p +  ++  lsv+ ++++++k++   + s 
  tr|F6W6K7|F6W6K7_MACMU 184 TAGVPLKVFGMFPSRGEKRALWKLAYdlyscssIYKFGRIEINMFIGEKEFQKLMADPrNRGLYYVLSVVWQVACEIKVLHMEPWSs 270
                             777777777777775444443333336999*99999999999888766666666665527789*****************9999999 PP

                             .................CECS--SSSEEEEEEEE-SS-S.--S...-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T- CS
                  RrnaAD 177 .................ifsPppkvdsalvelerkdedl.pqk...dlkkyesvvrkllnrkrktlstslksllpggelqalsstgi 242
                                              +  +  + ++ l++++++ + + + +   +++ +  ++++++ +++ t+   l sl+p ++++ l + g 
  tr|F6W6K7|F6W6K7_MACMU 271 fdvytrsgrlentkrkeV-LELLQQNLYLIQMTPRRNLFaNSLtpmNYNIFFHLLKHCFGKRSATVIDHLRSLTPLDAADILMQIGK 356
                             ***********9999963.56667799********9988765423378899999************************999977789 PP

                             -TTTCCCCSGHHHHHHHHHHH CS
                  RrnaAD 243 ndnalvkklsaeqtldifkel 263
                             +++ +v++  +e++ ++f+ +
  tr|F6W6K7|F6W6K7_MACMU 357 KEDEKVVNMYPEDFKRLFETI 377
                             9999***********999987 PP

>> tr|A0A1D5QK90|A0A1D5QK90_MACMU  rRNA adenine N(6)-methyltransferase OS=Macaca mulatta OX=9544 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   0.0   4.7e-11   1.4e-07      30      90 ..      85     146 ..      60     151 .. 0.83
   2 !    7.7   0.0   0.00062       1.9     159     263 ..     207     332 ..     186     333 .. 0.69

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 4.7e-11
                                     TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHH CS
                          RrnaAD  30 ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls.kdeklkvvhqDflkfet 90 
                                     +   +l   pG+GilT+ L++   + v+lE+d+ ++++l+   + +d+kl+v h+Df k + 
  tr|A0A1D5QK90|A0A1D5QK90_MACMU  85 PPHLLLQCNPGPGILTQALLEVDAKAVALESDKTFIAHLESLGKnLDGKLQVSHCDFFKIDP 146
                                     555678999*******************************97669*************9876 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00062
                                     HHHHHHEEEEEEEEC-GG..................CECS--SSSEEEEEEEE-SS-S.--S-...HHHHHHHHHHHHC CS
                          RrnaAD 159 vlreaftdvklvakveks..................ifsPppkvdsalvelerkdedl.pqkd...lkkyesvvrklln 215
                                     v+ +a++++k++   + s                  +  +  + ++ l+++++  + + +++    ++ +  +++++++
  tr|A0A1D5QK90|A0A1D5QK90_MACMU 207 VIWHAACEIKVLHMEPWSsfdvytrngrlenpkhreL-LELLQHNLYLIRMTPCGNLFtKNLTlihYNIFFHMLKHCFV 284
                                     5566666666666655556666666666444444421.223344668999999888887776611145566889***** PP

                                     TTTSBCCCHCCCTSTCHHHHHCTT.T--TTTCCCCSGHHHHHHHHHHH CS
                          RrnaAD 216 rkrktlstslksllpggelqalsstgindnalvkklsaeqtldifkel 263
                                     r++ ++   l sl+p ++++ l + g +++ +++++ ++++ ++f+ +
  tr|A0A1D5QK90|A0A1D5QK90_MACMU 285 RRSANVIDHLRSLTPLDAMDILPQIGKKEEEKITNVYPQNFKKLFETI 332
                                     ***************999998866577788888888888888888765 PP

>> tr|G7MS35|G7MS35_MACMU  Protein arginine methyltransferase 9 OS=Macaca mulatta OX=9544 GN=PRMT10 PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   2.4e-06    0.0072      16      94 ..     163     245 ..     157     263 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 2.4e-06
                             HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHH CS
                  RrnaAD  16 kkvineIldklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeev 94 
                             ++++n +++k+    +  vl+ig+G+Gil+  +ak a   +v + El + +++l  + +     +  +k++h   l+ e+p+ +
  tr|G7MS35|G7MS35_MACMU 163 NTIYNAAIQKAVCLGSRSVLDIGAGTGILSM-FAKKAgaHSVYACELSKTMYELACDVVAankMEAGIKLLHMKSLDIEIPKHI 245
                             6799*************************97.566665899999*********9988776666677788888888888888755 PP

>> tr|F6UBC5|F6UBC5_MACMU  Protein RRNAD1 isoform 1 OS=Macaca mulatta OX=9544 GN=RRNAD1 PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   4.1e-05      0.12      32      70 ..     155     194 ..     143     218 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 4.1e-05
                             SEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHC CS
                  RrnaAD  32 ltvleigpGkGilTeeLakra.kqvvvlElderLakllqk 70 
                             ++v+++g+G+G+l++ +a  +   v ++E d+rL+++ q 
  tr|F6UBC5|F6UBC5_MACMU 155 TQVVDVGSGQGHLSRFMALGLgLMVKSIEGDQRLVERAQR 194
                             79***************888879999**********9997 PP

>> tr|F7D1K5|F7D1K5_MACMU  tRNA methyltransferase 61B OS=Macaca mulatta OX=9544 GN=TRMT61B PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00013      0.39      19      69 ..     235     288 ..     229     317 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00013
                             HHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHH CS
                  RrnaAD  19 ineIldklnleekltvleigpGkGilTeeLakra...kqvvvlElderLakllq 69 
                             i  Il  +++++ +tvle g+G G ++  L k +     v ++E +++   l +
  tr|F7D1K5|F7D1K5_MACMU 235 ISMILLMMDISPGDTVLEAGSGSGGMSLFLSKAVgsqGRVISFEVRKDHHDLAK 288
                             77899999**********************999987777889998876444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (265 nodes)
Target sequences:                        21211  (10888574 residues searched)
Passed MSV filter:                       605  (0.0285229); expected 424.2 (0.02)
Passed bias filter:                      395  (0.0186224); expected 424.2 (0.02)
Passed Vit filter:                        66  (0.00311159); expected 21.2 (0.001)
Passed Fwd filter:                         7  (0.000330017); expected 0.2 (1e-05)
Initial search space (Z):              21211  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.23u 0.01s 00:00:00.24 Elapsed: 00:00:00.08
# Mc/sec: 36068.40
//
[ok]