# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/RrnaAD.hmm.txt # target sequence database: proteomes/Macaca_mulatta.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: RrnaAD [M=265] Accession: PF00398.19 Description: Ribosomal RNA adenine dimethylase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5e-66 222.7 0.0 6.1e-66 222.4 0.0 1.1 1 tr|F6X5A5|F6X5A5_MACMU rRNA adenine N(6)-methyltransfer 1.9e-42 145.4 0.0 2.4e-42 145.1 0.0 1.1 1 tr|F6VAH2|F6VAH2_MACMU rRNA adenine N(6)-methyltransfer 4.6e-17 62.2 0.0 9e-17 61.2 0.0 1.4 1 tr|F6W6K7|F6W6K7_MACMU rRNA adenine N(6)-methyltransfer 1.5e-10 40.8 0.0 1.4e-07 31.1 0.0 2.1 2 tr|A0A1D5QK90|A0A1D5QK90_MACMU rRNA adenine N(6)-methyltransfer 0.0033 16.8 0.0 0.0072 15.7 0.0 1.5 1 tr|G7MS35|G7MS35_MACMU Protein arginine methyltransfera ------ inclusion threshold ------ 0.078 12.3 0.0 0.12 11.6 0.0 1.2 1 tr|F6UBC5|F6UBC5_MACMU Protein RRNAD1 isoform 1 OS=Maca 0.18 11.1 0.0 0.39 10.0 0.0 1.5 1 tr|F7D1K5|F7D1K5_MACMU tRNA methyltransferase 61B OS=Ma Domain annotation for each sequence (and alignments): >> tr|F6X5A5|F6X5A5_MACMU rRNA adenine N(6)-methyltransferase OS=Macaca mulatta OX=9544 GN=DIMT1 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 222.4 0.0 2e-69 6.1e-66 4 237 .. 30 254 .. 27 274 .. 0.96 Alignments for each domain: == domain 1 score: 222.4 bits; conditional E-value: 2e-69 CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS RrnaAD 4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87 +++ gq++lkn+ +in+I+dk+ l++++ vle+gpG+G++T++L++ ak+vv+ Eld+rL+++l k+++ ++kl+v+ D+lk tr|F6X5A5|F6X5A5_MACMU 30 FNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQgtpVASKLQVLVGDVLK 116 78999*****************************************************************9999************* PP HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC- CS RrnaAD 88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakve 174 +++p + +vanlPy+is+++v++ll ++r+ ++ ++l++q+efa rl+a+pg+k+++rls+++++++ v +++kv+ tr|F6X5A5|F6X5A5_MACMU 117 TDLPFFD----------TCVANLPYQISSPFVFKLL-LHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVG 192 *****88..........6******************.788889******************************************** PP GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHC CS RrnaAD 175 ksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqal 237 k++f+Pppkv+s++v++e+k+++ p + ++++ +vr+ ++rk+ktls+++ks ++ l+++ tr|F6X5A5|F6X5A5_MACMU 193 KNNFRPPPKVESSVVRIEPKNPP-PPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKN 254 **********************8.89**************************98888877766 PP >> tr|F6VAH2|F6VAH2_MACMU rRNA adenine N(6)-methyltransferase OS=Macaca mulatta OX=9544 GN=TFB1M PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 145.1 0.0 8e-46 2.4e-42 3 243 .. 28 281 .. 26 302 .. 0.90 Alignments for each domain: == domain 1 score: 145.1 bits; conditional E-value: 8e-46 CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCG CS RrnaAD 3 klrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls.kdeklkvvhqDflk 87 ++ k+++qnfl + + ++I++k+ + v+e+gpG+G T+++++ ++ v+E+d+r++ lq + +kl +vh D+l+ tr|F6VAH2|F6VAH2_MACMU 28 QATKQLSQNFLLDLRLTDKIVRKAGNLANAYVYEVGPGPGGITRSILNADvAELLVVEKDTRFIPGLQMLSEaAPGKLRIVHGDVLT 114 67799***************************************9966655******************6558889*********** PP HHHHHHHCT.....TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHH CS RrnaAD 88 fetpeevte.....kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlre 162 f++ + e + + +++nlP +st+l+ ++le g+ +m+l +qke+a+rl+a+ gsk+rsrlsv+++ tr|F6VAH2|F6VAH2_MACMU 115 FKVEKAFSEslkrpWEDDPPNVHIIGNLPFSVSTPLIIKWLEniscrdgPFVYGRTQMTLTFQKEVAERLAANTGSKQRSRLSVMAQ 201 *****998888887555667899*********************999885566789******************************* PP HHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T-- CS RrnaAD 163 aftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalsstgin 243 ++++v+++ +++ ++f P+p+vd +v ++ ++ ++ k e+vv+ ++ +rk l l+p++++ ++ ++ tr|F6VAH2|F6VAH2_MACMU 202 YLCNVRHIFTIPGRAFVPKPEVDVGVVHFTPLIQPKIEQPFKLVEKVVQNVFQFRRKYCHRGLGMLFPEAQRLENTG-RLL 281 ******************************97665347788999**************************9887754.444 PP >> tr|F6W6K7|F6W6K7_MACMU rRNA adenine N(6)-methyltransferase OS=Macaca mulatta OX=9544 GN=TFB2M PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.2 0.0 3e-20 9e-17 32 263 .. 97 377 .. 80 379 .. 0.83 Alignments for each domain: == domain 1 score: 61.2 bits; conditional E-value: 3e-20 SEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHHCT...................TT CS RrnaAD 32 ltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeevte...................kd 98 +le pG+GilTe L++ vv+lE+d+ ++ +l+ + +d+kl v+h+Df + + tr|F6W6K7|F6W6K7_MACMU 97 HLLLECNPGPGILTEALLEAGATVVALESDKTFIPHLESLGKnLDGKLRVIHCDFFRIDPRSGGAIkppamsseglfknlgveevPW 183 5689**********************************97669*****************99433379*997777777777777766 PP CCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--T.TSTT-SHHHHHHHHHEEEEEEEEC-GG. CS RrnaAD 99 sihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarp.gskkrsrlsvlreaftdvklvakveks. 176 + +++v++ P + +l ++fg+ ++ + + ++ ++l+a+p + ++ lsv+ ++++++k++ + s tr|F6W6K7|F6W6K7_MACMU 184 TAGVPLKVFGMFPSRGEKRALWKLAYdlyscssIYKFGRIEINMFIGEKEFQKLMADPrNRGLYYVLSVVWQVACEIKVLHMEPWSs 270 777777777777775444443333336999*99999999999888766666666665527789*****************9999999 PP .................CECS--SSSEEEEEEEE-SS-S.--S...-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T- CS RrnaAD 177 .................ifsPppkvdsalvelerkdedl.pqk...dlkkyesvvrkllnrkrktlstslksllpggelqalsstgi 242 + + + ++ l++++++ + + + + +++ + ++++++ +++ t+ l sl+p ++++ l + g tr|F6W6K7|F6W6K7_MACMU 271 fdvytrsgrlentkrkeV-LELLQQNLYLIQMTPRRNLFaNSLtpmNYNIFFHLLKHCFGKRSATVIDHLRSLTPLDAADILMQIGK 356 ***********9999963.56667799********9988765423378899999************************999977789 PP -TTTCCCCSGHHHHHHHHHHH CS RrnaAD 243 ndnalvkklsaeqtldifkel 263 +++ +v++ +e++ ++f+ + tr|F6W6K7|F6W6K7_MACMU 357 KEDEKVVNMYPEDFKRLFETI 377 9999***********999987 PP >> tr|A0A1D5QK90|A0A1D5QK90_MACMU rRNA adenine N(6)-methyltransferase OS=Macaca mulatta OX=9544 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.1 0.0 4.7e-11 1.4e-07 30 90 .. 85 146 .. 60 151 .. 0.83 2 ! 7.7 0.0 0.00062 1.9 159 263 .. 207 332 .. 186 333 .. 0.69 Alignments for each domain: == domain 1 score: 31.1 bits; conditional E-value: 4.7e-11 TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHH CS RrnaAD 30 ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls.kdeklkvvhqDflkfet 90 + +l pG+GilT+ L++ + v+lE+d+ ++++l+ + +d+kl+v h+Df k + tr|A0A1D5QK90|A0A1D5QK90_MACMU 85 PPHLLLQCNPGPGILTQALLEVDAKAVALESDKTFIAHLESLGKnLDGKLQVSHCDFFKIDP 146 555678999*******************************97669*************9876 PP == domain 2 score: 7.7 bits; conditional E-value: 0.00062 HHHHHHEEEEEEEEC-GG..................CECS--SSSEEEEEEEE-SS-S.--S-...HHHHHHHHHHHHC CS RrnaAD 159 vlreaftdvklvakveks..................ifsPppkvdsalvelerkdedl.pqkd...lkkyesvvrklln 215 v+ +a++++k++ + s + + + ++ l+++++ + + +++ ++ + +++++++ tr|A0A1D5QK90|A0A1D5QK90_MACMU 207 VIWHAACEIKVLHMEPWSsfdvytrngrlenpkhreL-LELLQHNLYLIRMTPCGNLFtKNLTlihYNIFFHMLKHCFV 284 5566666666666655556666666666444444421.223344668999999888887776611145566889***** PP TTTSBCCCHCCCTSTCHHHHHCTT.T--TTTCCCCSGHHHHHHHHHHH CS RrnaAD 216 rkrktlstslksllpggelqalsstgindnalvkklsaeqtldifkel 263 r++ ++ l sl+p ++++ l + g +++ +++++ ++++ ++f+ + tr|A0A1D5QK90|A0A1D5QK90_MACMU 285 RRSANVIDHLRSLTPLDAMDILPQIGKKEEEKITNVYPQNFKKLFETI 332 ***************999998866577788888888888888888765 PP >> tr|G7MS35|G7MS35_MACMU Protein arginine methyltransferase 9 OS=Macaca mulatta OX=9544 GN=PRMT10 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 2.4e-06 0.0072 16 94 .. 163 245 .. 157 263 .. 0.83 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 2.4e-06 HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHH CS RrnaAD 16 kkvineIldklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeev 94 ++++n +++k+ + vl+ig+G+Gil+ +ak a +v + El + +++l + + + +k++h l+ e+p+ + tr|G7MS35|G7MS35_MACMU 163 NTIYNAAIQKAVCLGSRSVLDIGAGTGILSM-FAKKAgaHSVYACELSKTMYELACDVVAankMEAGIKLLHMKSLDIEIPKHI 245 6799*************************97.566665899999*********9988776666677788888888888888755 PP >> tr|F6UBC5|F6UBC5_MACMU Protein RRNAD1 isoform 1 OS=Macaca mulatta OX=9544 GN=RRNAD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 4.1e-05 0.12 32 70 .. 155 194 .. 143 218 .. 0.85 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4.1e-05 SEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHC CS RrnaAD 32 ltvleigpGkGilTeeLakra.kqvvvlElderLakllqk 70 ++v+++g+G+G+l++ +a + v ++E d+rL+++ q tr|F6UBC5|F6UBC5_MACMU 155 TQVVDVGSGQGHLSRFMALGLgLMVKSIEGDQRLVERAQR 194 79***************888879999**********9997 PP >> tr|F7D1K5|F7D1K5_MACMU tRNA methyltransferase 61B OS=Macaca mulatta OX=9544 GN=TRMT61B PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.0 0.0 0.00013 0.39 19 69 .. 235 288 .. 229 317 .. 0.81 Alignments for each domain: == domain 1 score: 10.0 bits; conditional E-value: 0.00013 HHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHH CS RrnaAD 19 ineIldklnleekltvleigpGkGilTeeLakra...kqvvvlElderLakllq 69 i Il +++++ +tvle g+G G ++ L k + v ++E +++ l + tr|F7D1K5|F7D1K5_MACMU 235 ISMILLMMDISPGDTVLEAGSGSGGMSLFLSKAVgsqGRVISFEVRKDHHDLAK 288 77899999**********************999987777889998876444444 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 21211 (10888574 residues searched) Passed MSV filter: 605 (0.0285229); expected 424.2 (0.02) Passed bias filter: 395 (0.0186224); expected 424.2 (0.02) Passed Vit filter: 66 (0.00311159); expected 21.2 (0.001) Passed Fwd filter: 7 (0.000330017); expected 0.2 (1e-05) Initial search space (Z): 21211 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.23u 0.01s 00:00:00.24 Elapsed: 00:00:00.08 # Mc/sec: 36068.40 // [ok]