# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/RrnaAD.hmm.txt # target sequence database: proteomes/Monodelphis_domestica.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: RrnaAD [M=265] Accession: PF00398.19 Description: Ribosomal RNA adenine dimethylase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-66 222.9 0.0 5.3e-66 222.6 0.0 1.1 1 tr|F6QCM9|F6QCM9_MONDO rRNA adenine N(6)-methyltransferase O 3.9e-40 137.9 0.0 4.9e-40 137.5 0.0 1.1 1 tr|F7EKY1|F7EKY1_MONDO rRNA adenine N(6)-methyltransferase O 2.6e-08 33.5 0.1 3.9e-08 32.9 0.1 1.3 1 tr|K7E385|K7E385_MONDO rRNA adenine N(6)-methyltransferase O 1.9e-05 24.1 0.0 2.9e-05 23.5 0.0 1.3 1 tr|F7FVV1|F7FVV1_MONDO Ribosomal RNA adenine dimethylase dom ------ inclusion threshold ------ 0.03 13.6 0.0 0.068 12.5 0.0 1.5 1 tr|F6WM17|F6WM17_MONDO Protein arginine methyltransferase 9 0.073 12.4 0.0 0.12 11.7 0.0 1.4 1 tr|F6XFW3|F6XFW3_MONDO Methyltransferase like 22 OS=Monodelp Domain annotation for each sequence (and alignments): >> tr|F6QCM9|F6QCM9_MONDO rRNA adenine N(6)-methyltransferase OS=Monodelphis domestica OX=13616 GN=DIMT1 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 222.6 0.0 1.5e-69 5.3e-66 4 238 .. 98 323 .. 95 346 .. 0.94 Alignments for each domain: == domain 1 score: 222.6 bits; conditional E-value: 1.5e-69 CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS RrnaAD 4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87 +++ +gq++lkn+ ++n+I+dk+ l++++ vle+gpG+G++T++L++ ak+vv+ Eld+rL+++l k+++ +++kl+v+ D+lk tr|F6QCM9|F6QCM9_MONDO 98 FNTGLGQHILKNPLIVNSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQgtpQASKLQVMVGDVLK 184 78999******************************************************************999************* PP HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC- CS RrnaAD 88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakve 174 +++p + ++vanlPy+is+++v++ll ++r+ ++ ++l++q+efa rl+a+pg+k+++rls+++++++ v +++kv+ tr|F6QCM9|F6QCM9_MONDO 185 TDLPFFD----------ACVANLPYQISSPFVFKLL-LHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVG 260 *****77..........8******************.788889******************************************** PP GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCT CS RrnaAD 175 ksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqals 238 k++f+Pppkv+s++v++e+k+++ p + ++++ +vr+ ++rk+ktls+++ks ++ l++++ tr|F6QCM9|F6QCM9_MONDO 261 KNNFRPPPKVESSVVRIEPKNPP-PPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNY 323 **********************8.89************************99888877777664 PP >> tr|F7EKY1|F7EKY1_MONDO rRNA adenine N(6)-methyltransferase OS=Monodelphis domestica OX=13616 GN=TFB1M PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 137.5 0.0 1.4e-43 4.9e-40 3 246 .. 28 284 .. 26 302 .. 0.89 Alignments for each domain: == domain 1 score: 137.5 bits; conditional E-value: 1.4e-43 CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHH.HCC-SEEEEE-S-HHHHHHHHCHTT..TCCCEEEE-S-CC CS RrnaAD 3 klrksygqnflknkkvineIldklnleekltvleigpGkGilTeeL.akrakqvvvlElderLakllqkkls..kdeklkvvhqDfl 86 +++k+++qnfl + + ++I++k+ ++ v+e+gpG+G++T+++ + ++ + v+E+d+r++ lq ls +kl +vh D+l tr|F7EKY1|F7EKY1_MONDO 28 RAQKQLSQNFLLDLRLTDKIVRKTGDLKNAHVYEVGPGPGAFTRSIlNAQVADLLVVEKDTRFIPGLQM-LSdaAPGKLRIVHGDVL 113 6789****************************************9945566******************.5558889********** PP GHHHHHHHCT.....TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHH CS RrnaAD 87 kfetpeevte.....kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlr 161 +f++ e + + +++nlP +st+l+ ++le g+ +m+l +qke+a+rl+a g+k+rsrls+++ tr|F7EKY1|F7EKY1_MONDO 114 TFKVERMFPEhlkrrWEDDPPNVYIIGNLPFSVSTPLIIKWLEniskrdgPFVYGRTQMTLTFQKEVAERLTAGTGNKQRSRLSIMA 200 ***99966668877633444568899*******************988775556789****************************** PP HHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T--TTT CS RrnaAD 162 eaftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalsstgindna 246 ++++ v +++ ++f P+p+vd +v ++ ++ ++ k e+vv+ + +rk + l+p++e+ +++++ + + a tr|F7EKY1|F7EKY1_MONDO 201 QYLCKVDNSFIIPGRAFVPKPEVDVGVVHFTPLVQPQINQPFKLVEKVVQSTFQFRRKYCHHGIGILFPQAERSKNTEK-MLMLA 284 ********************************9886567789999****************************999885.44444 PP >> tr|K7E385|K7E385_MONDO rRNA adenine N(6)-methyltransferase OS=Monodelphis domestica OX=13616 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.9 0.1 1.1e-11 3.9e-08 45 263 .. 3 265 .. 1 267 [. 0.84 Alignments for each domain: == domain 1 score: 32.9 bits; conditional E-value: 1.1e-11 HHHHHCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHHCT...................TTCCCCEEEEEEE-- CS RrnaAD 45 TeeLakrakqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeevte...................kdsihqeflvvanlP 111 T L++ qv +lE d+ ++ l+ + ++++l+v+ +Df + ++ + + ++v+ P tr|K7E385|K7E385_MONDO 3 TSALLNAGLQVIALERDRTFLPYLESLKNhLNGQLEVIYCDFFSRDPSNNRATtppplftetlfknfgireiPWEADVPVKIVGFFP 89 778888889************99999444899***************9977779***************999889999********* PP T.TTHHHHHHHHHH......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GG.............CE CS RrnaAD 112 y.eistqlvkqlle......esrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveks.............if 178 + ++l k l + + g+ + + + ++ +++++++p +k ++ lsvl +++ ++kl+ + s + tr|K7E385|K7E385_MONDO 90 VkNERSALWKFLYDlyscssIYDYGRIELNMFISEKEYKKIISKPDEKFYQPLSVLCQTAYEIKLLHMEPLSsfvtfksgkfqsfKC 176 9777788888888899999988899999**************************************9999999**********9955 PP CS--SSSEEEEEEEE-SS-S.--S...-HHHHHHHHHHHHCTTTSBCCCHCCC..TSTCHHHHHCTT.T--TTTCCCCSGHHHHHHH CS RrnaAD 179 sPppkvdsalvelerkdedl.pqk...dlkkyesvvrkllnrkrktlstslks..llpggelqalsstgindnalvkklsaeqtldi 259 ++ + + ++l+++ + + +++ + ++ ++v++++++++ +l ++s + ++g l ++ n+ ++v+ l++e++ + tr|K7E385|K7E385_MONDO 177 KESKNKHLNFIRLTPRRNLFtDNLtpmNSCNFMYLVKQCFTKRKYKLIDLFNSwsICNKGDLLQQLNR--NKHDPVGSLEPEEFKYL 261 88889999*********99977652225679**********999887655554114444443333344..88889999999988888 PP HHHH CS RrnaAD 260 fkel 263 f+ l tr|K7E385|K7E385_MONDO 262 FEVL 265 7765 PP >> tr|F7FVV1|F7FVV1_MONDO Ribosomal RNA adenine dimethylase domain containing 1 OS=Monodelphis domestica OX=13616 GN=RR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.5 0.0 8.2e-09 2.9e-05 26 82 .. 149 204 .. 107 217 .. 0.88 Alignments for each domain: == domain 1 score: 23.5 bits; conditional E-value: 8.2e-09 H-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTTTCCCEEEE- CS RrnaAD 26 lnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkklskdeklkvvh 82 ++l+ +v+++g+G+G+lT+ La + +v+ +E+d++L+++ q+ ++e l +++ tr|F7FVV1|F7FVV1_MONDO 149 SDLTSCNQVVDVGSGQGHLTRFLALGLgLSVTGIEKDRKLVERAQH--LDQELLSILK 204 4788899****************88888****************99..5566666655 PP >> tr|F6WM17|F6WM17_MONDO Protein arginine methyltransferase 9 OS=Monodelphis domestica OX=13616 GN=PRMT9 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.0 1.9e-05 0.068 18 94 .. 160 240 .. 152 265 .. 0.83 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 1.9e-05 HHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHH CS RrnaAD 18 vineIldklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeev 94 ++n++++k+ +tvl+ig+G+Gil+ +ak a v + El + +++l + + ++ +k++h l+ ++p+ + tr|F6WM17|F6WM17_MONDO 160 TYNSAIQKVVRLGCKTVLDIGAGTGILSM-FAKNAgaHRVYACELSKTMYELACDVVAankMETGIKLLHMKSLDIDVPKHI 240 677777777777889************97.55555579999**********9999777777788899999999999999865 PP >> tr|F6XFW3|F6XFW3_MONDO Methyltransferase like 22 OS=Monodelphis domestica OX=13616 GN=METTL22 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 3.4e-05 0.12 19 76 .. 194 251 .. 191 339 .. 0.78 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 3.4e-05 HHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTTTCC CS RrnaAD 19 ineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkklskde 76 ++ Il + +l ++ tvle+g+G+Gi + + a ak v e+L+ + + ++ +++ tr|F6XFW3|F6XFW3_MONDO 194 ADYILFQRDLFKSCTVLELGAGTGIASIITATVAKTVYCTDVGEDLLTMCERNVALNK 251 67799999999*************9988888888877766666666665555544443 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 21272 (11266248 residues searched) Passed MSV filter: 919 (0.0432023); expected 425.4 (0.02) Passed bias filter: 469 (0.0220478); expected 425.4 (0.02) Passed Vit filter: 55 (0.00258556); expected 21.3 (0.001) Passed Fwd filter: 6 (0.000282061); expected 0.2 (1e-05) Initial search space (Z): 21272 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.23u 0.01s 00:00:00.24 Elapsed: 00:00:00.09 # Mc/sec: 33172.84 // [ok]