# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/RrnaAD.hmm.txt
# target sequence database:        proteomes/Monodelphis_domestica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       RrnaAD  [M=265]
Accession:   PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    4.5e-66  222.9   0.0    5.3e-66  222.6   0.0    1.1  1  tr|F6QCM9|F6QCM9_MONDO  rRNA adenine N(6)-methyltransferase O
    3.9e-40  137.9   0.0    4.9e-40  137.5   0.0    1.1  1  tr|F7EKY1|F7EKY1_MONDO  rRNA adenine N(6)-methyltransferase O
    2.6e-08   33.5   0.1    3.9e-08   32.9   0.1    1.3  1  tr|K7E385|K7E385_MONDO  rRNA adenine N(6)-methyltransferase O
    1.9e-05   24.1   0.0    2.9e-05   23.5   0.0    1.3  1  tr|F7FVV1|F7FVV1_MONDO  Ribosomal RNA adenine dimethylase dom
  ------ inclusion threshold ------
       0.03   13.6   0.0      0.068   12.5   0.0    1.5  1  tr|F6WM17|F6WM17_MONDO  Protein arginine methyltransferase 9 
      0.073   12.4   0.0       0.12   11.7   0.0    1.4  1  tr|F6XFW3|F6XFW3_MONDO  Methyltransferase like 22 OS=Monodelp


Domain annotation for each sequence (and alignments):
>> tr|F6QCM9|F6QCM9_MONDO  rRNA adenine N(6)-methyltransferase OS=Monodelphis domestica OX=13616 GN=DIMT1 PE=3 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  222.6   0.0   1.5e-69   5.3e-66       4     238 ..      98     323 ..      95     346 .. 0.94

  Alignments for each domain:
  == domain 1  score: 222.6 bits;  conditional E-value: 1.5e-69
                             CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS
                  RrnaAD   4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87 
                             +++ +gq++lkn+ ++n+I+dk+ l++++ vle+gpG+G++T++L++ ak+vv+ Eld+rL+++l k+++   +++kl+v+  D+lk
  tr|F6QCM9|F6QCM9_MONDO  98 FNTGLGQHILKNPLIVNSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQgtpQASKLQVMVGDVLK 184
                             78999******************************************************************999************* PP

                             HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC- CS
                  RrnaAD  88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakve 174
                             +++p +           ++vanlPy+is+++v++ll ++r+ ++ ++l++q+efa rl+a+pg+k+++rls+++++++ v +++kv+
  tr|F6QCM9|F6QCM9_MONDO 185 TDLPFFD----------ACVANLPYQISSPFVFKLL-LHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVG 260
                             *****77..........8******************.788889******************************************** PP

                             GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCT CS
                  RrnaAD 175 ksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqals 238
                             k++f+Pppkv+s++v++e+k+++ p  + ++++ +vr+ ++rk+ktls+++ks   ++ l++++
  tr|F6QCM9|F6QCM9_MONDO 261 KNNFRPPPKVESSVVRIEPKNPP-PPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNY 323
                             **********************8.89************************99888877777664 PP

>> tr|F7EKY1|F7EKY1_MONDO  rRNA adenine N(6)-methyltransferase OS=Monodelphis domestica OX=13616 GN=TFB1M PE=3 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.5   0.0   1.4e-43   4.9e-40       3     246 ..      28     284 ..      26     302 .. 0.89

  Alignments for each domain:
  == domain 1  score: 137.5 bits;  conditional E-value: 1.4e-43
                             CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHH.HCC-SEEEEE-S-HHHHHHHHCHTT..TCCCEEEE-S-CC CS
                  RrnaAD   3 klrksygqnflknkkvineIldklnleekltvleigpGkGilTeeL.akrakqvvvlElderLakllqkkls..kdeklkvvhqDfl 86 
                             +++k+++qnfl +  + ++I++k+   ++  v+e+gpG+G++T+++ + ++  + v+E+d+r++  lq  ls    +kl +vh D+l
  tr|F7EKY1|F7EKY1_MONDO  28 RAQKQLSQNFLLDLRLTDKIVRKTGDLKNAHVYEVGPGPGAFTRSIlNAQVADLLVVEKDTRFIPGLQM-LSdaAPGKLRIVHGDVL 113
                             6789****************************************9945566******************.5558889********** PP

                             GHHHHHHHCT.....TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHH CS
                  RrnaAD  87 kfetpeevte.....kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlr 161
                             +f++     e        +  +  +++nlP  +st+l+ ++le           g+ +m+l +qke+a+rl+a  g+k+rsrls+++
  tr|F7EKY1|F7EKY1_MONDO 114 TFKVERMFPEhlkrrWEDDPPNVYIIGNLPFSVSTPLIIKWLEniskrdgPFVYGRTQMTLTFQKEVAERLTAGTGNKQRSRLSIMA 200
                             ***99966668877633444568899*******************988775556789****************************** PP

                             HHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T--TTT CS
                  RrnaAD 162 eaftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalsstgindna 246
                             ++++ v    +++ ++f P+p+vd  +v  ++  ++  ++  k  e+vv+  +  +rk     +  l+p++e+ +++++ + + a
  tr|F7EKY1|F7EKY1_MONDO 201 QYLCKVDNSFIIPGRAFVPKPEVDVGVVHFTPLVQPQINQPFKLVEKVVQSTFQFRRKYCHHGIGILFPQAERSKNTEK-MLMLA 284
                             ********************************9886567789999****************************999885.44444 PP

>> tr|K7E385|K7E385_MONDO  rRNA adenine N(6)-methyltransferase OS=Monodelphis domestica OX=13616 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9   0.1   1.1e-11   3.9e-08      45     263 ..       3     265 ..       1     267 [. 0.84

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 1.1e-11
                             HHHHHCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHHCT...................TTCCCCEEEEEEE-- CS
                  RrnaAD  45 TeeLakrakqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeevte...................kdsihqeflvvanlP 111
                             T  L++   qv +lE d+ ++  l+   + ++++l+v+ +Df   +  ++                        +   + ++v+  P
  tr|K7E385|K7E385_MONDO   3 TSALLNAGLQVIALERDRTFLPYLESLKNhLNGQLEVIYCDFFSRDPSNNRATtppplftetlfknfgireiPWEADVPVKIVGFFP 89 
                             778888889************99999444899***************9977779***************999889999********* PP

                             T.TTHHHHHHHHHH......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GG.............CE CS
                  RrnaAD 112 y.eistqlvkqlle......esrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveks.............if 178
                               +  ++l k l +       +  g+ +  + + ++ +++++++p +k ++ lsvl +++ ++kl+   + s             + 
  tr|K7E385|K7E385_MONDO  90 VkNERSALWKFLYDlyscssIYDYGRIELNMFISEKEYKKIISKPDEKFYQPLSVLCQTAYEIKLLHMEPLSsfvtfksgkfqsfKC 176
                             9777788888888899999988899999**************************************9999999**********9955 PP

                             CS--SSSEEEEEEEE-SS-S.--S...-HHHHHHHHHHHHCTTTSBCCCHCCC..TSTCHHHHHCTT.T--TTTCCCCSGHHHHHHH CS
                  RrnaAD 179 sPppkvdsalvelerkdedl.pqk...dlkkyesvvrkllnrkrktlstslks..llpggelqalsstgindnalvkklsaeqtldi 259
                             ++  +  +  ++l+++ + + +++   +  ++ ++v++++++++ +l   ++s  + ++g l    ++  n+ ++v+ l++e++  +
  tr|K7E385|K7E385_MONDO 177 KESKNKHLNFIRLTPRRNLFtDNLtpmNSCNFMYLVKQCFTKRKYKLIDLFNSwsICNKGDLLQQLNR--NKHDPVGSLEPEEFKYL 261
                             88889999*********99977652225679**********999887655554114444443333344..88889999999988888 PP

                             HHHH CS
                  RrnaAD 260 fkel 263
                             f+ l
  tr|K7E385|K7E385_MONDO 262 FEVL 265
                             7765 PP

>> tr|F7FVV1|F7FVV1_MONDO  Ribosomal RNA adenine dimethylase domain containing 1 OS=Monodelphis domestica OX=13616 GN=RR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.0   8.2e-09   2.9e-05      26      82 ..     149     204 ..     107     217 .. 0.88

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 8.2e-09
                             H-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTTTCCCEEEE- CS
                  RrnaAD  26 lnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkklskdeklkvvh 82 
                             ++l+   +v+++g+G+G+lT+ La  +  +v+ +E+d++L+++ q+   ++e l +++
  tr|F7FVV1|F7FVV1_MONDO 149 SDLTSCNQVVDVGSGQGHLTRFLALGLgLSVTGIEKDRKLVERAQH--LDQELLSILK 204
                             4788899****************88888****************99..5566666655 PP

>> tr|F6WM17|F6WM17_MONDO  Protein arginine methyltransferase 9 OS=Monodelphis domestica OX=13616 GN=PRMT9 PE=3 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.9e-05     0.068      18      94 ..     160     240 ..     152     265 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.9e-05
                             HHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHH CS
                  RrnaAD  18 vineIldklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeev 94 
                             ++n++++k+     +tvl+ig+G+Gil+  +ak a    v + El + +++l  + +     ++ +k++h   l+ ++p+ +
  tr|F6WM17|F6WM17_MONDO 160 TYNSAIQKVVRLGCKTVLDIGAGTGILSM-FAKNAgaHRVYACELSKTMYELACDVVAankMETGIKLLHMKSLDIDVPKHI 240
                             677777777777889************97.55555579999**********9999777777788899999999999999865 PP

>> tr|F6XFW3|F6XFW3_MONDO  Methyltransferase like 22 OS=Monodelphis domestica OX=13616 GN=METTL22 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   3.4e-05      0.12      19      76 ..     194     251 ..     191     339 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 3.4e-05
                             HHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTTTCC CS
                  RrnaAD  19 ineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkklskde 76 
                             ++ Il + +l ++ tvle+g+G+Gi + + a  ak v      e+L+ + + ++ +++
  tr|F6XFW3|F6XFW3_MONDO 194 ADYILFQRDLFKSCTVLELGAGTGIASIITATVAKTVYCTDVGEDLLTMCERNVALNK 251
                             67799999999*************9988888888877766666666665555544443 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (265 nodes)
Target sequences:                        21272  (11266248 residues searched)
Passed MSV filter:                       919  (0.0432023); expected 425.4 (0.02)
Passed bias filter:                      469  (0.0220478); expected 425.4 (0.02)
Passed Vit filter:                        55  (0.00258556); expected 21.3 (0.001)
Passed Fwd filter:                         6  (0.000282061); expected 0.2 (1e-05)
Initial search space (Z):              21272  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.23u 0.01s 00:00:00.24 Elapsed: 00:00:00.09
# Mc/sec: 33172.84
//
[ok]