# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/RrnaAD.hmm.txt
# target sequence database:        proteomes/Monosiga_brevicollis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       RrnaAD  [M=265]
Accession:   PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    4.9e-65  218.3   0.0    7.1e-65  217.8   0.0    1.1  1  tr|A9V663|A9V663_MONBE  rRNA adenine N(6)-methyltransferase O
    1.1e-24   85.9   0.0      3e-18   64.9   0.0    2.1  2  tr|A9UY16|A9UY16_MONBE  rRNA adenine N(6)-methyltransferase O
    1.2e-07   30.1   0.0    2.1e-07   29.4   0.0    1.4  1  tr|A9UZ84|A9UZ84_MONBE  Predicted protein OS=Monosiga brevico
    1.8e-05   23.0   0.0    2.9e-05   22.3   0.0    1.2  1  tr|A9UV85|A9UV85_MONBE  Predicted protein OS=Monosiga brevico
    0.00084   17.5   0.1     0.0012   17.0   0.1    1.4  1  tr|A9VD27|A9VD27_MONBE  Predicted protein OS=Monosiga brevico
     0.0061   14.7   0.0     0.0094   14.1   0.0    1.2  1  tr|A9UQI2|A9UQI2_MONBE  Uncharacterized protein OS=Monosiga b
  ------ inclusion threshold ------
      0.015   13.4   0.0      0.025   12.7   0.0    1.3  1  tr|A9V6A5|A9V6A5_MONBE  Predicted protein OS=Monosiga brevico
      0.075   11.1   0.0      0.085   11.0   0.0    1.2  1  tr|A9UUG3|A9UUG3_MONBE  Predicted protein (Fragment) OS=Monos


Domain annotation for each sequence (and alignments):
>> tr|A9V663|A9V663_MONBE  rRNA adenine N(6)-methyltransferase OS=Monosiga brevicollis OX=81824 GN=27741 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  217.8   0.0   6.2e-68   7.1e-65       4     228 ..      37     252 ..      35     265 .. 0.96

  Alignments for each domain:
  == domain 1  score: 217.8 bits;  conditional E-value: 6.2e-68
                             CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS
                  RrnaAD   4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87 
                             ++k++gq++lkn+ v+++I+dk+ ++ ++tvleigpG+G+lT++L++  k+vv+ E d+rLa++lqk++    +++kl +v  D+lk
  tr|A9V663|A9V663_MONBE  37 FNKDFGQHILKNPLVVQGIIDKAAIKSTDTVLEIGPGTGNLTVKLLEKGKKVVACEVDPRLAAELQKRVMgtpLHRKLHLVMGDVLK 123
                             799******************************************************************9999************** PP

                             HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC- CS
                  RrnaAD  88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakve 174
                             +++p +            +van+Py+is+++v+++l ++r+ ++ ++l++q+efa+rl+a+pg+ +++rlsv++++++ v +v+kv+
  tr|A9V663|A9V663_MONBE 124 ADLPFFD----------VCVANMPYQISSPFVFKIL-LHRPLFRCAVLMFQREFAQRLVAKPGDALYCRLSVNTQLLARVDHVMKVG 199
                             *****77..........7******************.899999******************************************** PP

                             GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCT CS
                  RrnaAD 175 ksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksl 228
                             +++f+Pppkv+s++v++e+++++ p +d ++++ ++r++++rk+ktl + ++s+
  tr|A9V663|A9V663_MONBE 200 RNNFRPPPKVESSVVRIEPRNPP-PPVDFEEWDGLLRIAFIRKNKTLAACFHSK 252
                             **********************9.8**********************9987765 PP

>> tr|A9UY16|A9UY16_MONBE  rRNA adenine N(6)-methyltransferase OS=Monosiga brevicollis OX=81824 GN=24887 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0     2e-07   0.00023       3      53 ..      21      71 ..      19      78 .. 0.93
   2 !   64.9   0.0   2.6e-21     3e-18     131     230 ..      81     179 ..      73     190 .. 0.94

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 2e-07
                            CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-S CS
                  RrnaAD  3 klrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrak 53
                            +++k+++qnf+  +  +++ ++++    +  v+eig G+G lT+ +++ a+
  tr|A9UY16|A9UY16_MONBE 21 RAKKKLSQNFILHQPCADKFVRAAGDLRDRVVVEIGGGPGSLTRAILEAAR 71
                            689**********************99*******************99985 PP

  == domain 2  score: 64.9 bits;  conditional E-value: 2.6e-21
                             EEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTT CS
                  RrnaAD 131 vkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrk 217
                               m+l++q+e  +rl+a+p+s  r ++s +++ +++v + + +++++f P+p+vd  +v le+k+e+ p +d +++e v+r+l++  
  tr|A9UY16|A9UY16_MONBE  81 LAMTLIFQREYGERLFAPPNSLHRAKISAFVQQYCNVSPGYLLPRNVFVPEPRVDTMVVHLESKPEP-PAVDPAVFEDVLRHLFTTP 166
                             579***************************************************************9.8****************** PP

                             TSBCCCHCCCTST CS
                  RrnaAD 218 rktlstslksllp 230
                             r+ l++ ++ ll 
  tr|A9UY16|A9UY16_MONBE 167 RRLLRNGMQPLLG 179
                             *******998776 PP

>> tr|A9UZ84|A9UZ84_MONBE  Predicted protein OS=Monosiga brevicollis OX=81824 GN=25375 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   0.0   1.8e-10   2.1e-07       5     230 ..    1584    1843 ..    1580    1874 .. 0.75

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 1.8e-10
                              XXGCG--.EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-........SEEEEE-S-HHHHHHHHCHTTTCCCEEE CS
                  RrnaAD    5 rksygqn.flknkkvineIldklnleekltvleigpGkGilTeeLakra........kqvvvlElderLakllqkklskdeklkv 80  
                              r+s +q  f+ ++ +++ I  + ++ e   v+e ++G G+lT+ +++           + + l +d++ +++l++++   + l v
  tr|A9UZ84|A9UZ84_MONBE 1584 RSSASQPlFVMDPRLADLIAAHCDV-EGRHVYEQAAGAGLLTQAFLQHGaafvtgcnSSSSRLNIDPDCFERLTNAFP--KHLSV 1665
                              55555533999*************9.6789*************9976533345666777888*************887..55666 PP

                              E-S-....CCGHHHHHHHCT..........TTCCCCEEEEEEE--TTTHHHHHHHHHH.........GGGGCEEEEEEEEEHHHH CS
                  RrnaAD   81 vhqD....flkfetpeevte..........kdsihqeflvvanlPyeistqlvkqlle.........esrfglvkmllwlqkefa 142 
                              +++     ++   tpe v e          kd +   fl+   lP + +   +  +l          ++r    k + +l ++ a
  tr|A9UZ84|A9UZ84_MONBE 1666 INAHlsvlGYHQTTPEAVKEhednvlaarqKDLPRTLFLF---LPTHNGLGYITNVLYqlvafdspfSYRQ-SCKFYCLLNRKWA 1746
                              66652222466667776666999***98766666666666...5555555555555555555699988888.5999********* PP

                              HHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCECS--SSSE.....EEEEEEE-SS-S--S-....HHHHHHHHHHHHCTTT CS
                  RrnaAD  143 rrllarpgskkrsrlsvlreaftdvklvakveksifsPppkvds.....alvelerkdedlpqkd....lkkyesvvrkllnrkr 218 
                              ++l+a+pg+++  r++ l+++++dv  +   ++++fsPp  v        l+e+ +k+  ++ ++    l++y+  + kl++  +
  tr|A9UZ84|A9UZ84_MONBE 1747 QTLVADPGQSRFTRITALTKTLCDVHELRVFPRQLFSPPLDVYKkddtmHLLEIAPKASLPDSVStpvgLARYDETLLKLFAPNQ 1831
                              ***************************************6664355567899999999866444312226778888888888888 PP

                              SBCCCHCCCTST CS
                  RrnaAD  219 ktlstslksllp 230 
                               ++++ l+  + 
  tr|A9UZ84|A9UZ84_MONBE 1832 LPVRKLLEPYVD 1843
                              888887775555 PP

>> tr|A9UV85|A9UV85_MONBE  Predicted protein OS=Monosiga brevicollis OX=81824 GN=18255 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.0   2.5e-08   2.9e-05      27      82 ..      71     130 ..      61     139 .. 0.90

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 2.5e-08
                             -GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE- CS
                  RrnaAD  27 nleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls...kdeklkvvh 82 
                             ++++++ vleig+G G+l    ak   ++v ++E  +++a+l q+ +s   ++ +++v++
  tr|A9UV85|A9UV85_MONBE  71 QIQPSDIVLEIGTGSGLLAMLAAKAGaRHVYAIEANRHMAQLAQHIISvngLADRITVIN 130
                             799***************988888778******************999889999999998 PP

>> tr|A9VD27|A9VD27_MONBE  Predicted protein OS=Monosiga brevicollis OX=81824 GN=34649 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.1   1.1e-06    0.0012      25      73 ..      41      93 ..      28     144 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 1.1e-06
                            HH-GG....TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT CS
                  RrnaAD 25 klnle....ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls 73
                            ++n +    ++l vle+g G G+l+ eLa r+k v +     ++++ l+++  
  tr|A9VD27|A9VD27_MONBE 41 QINKRgldwKQLSVLEVGCGAGVLSLELAARVKDVLAADPSAAMIAKLKERQA 93
                            4444466689***************************9999999999999655 PP

>> tr|A9UQI2|A9UQI2_MONBE  Uncharacterized protein OS=Monosiga brevicollis OX=81824 GN=21077 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   0.0   8.2e-06    0.0094      30      76 ..      60     108 ..      37     113 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 8.2e-06
                             TTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTTTCC CS
                  RrnaAD  30 ekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkklskde 76 
                             e +  l++g+G G  Te+L+  a  k v +l +d+r++   +++ls+ +
  tr|A9UQI2|A9UQI2_MONBE  60 ERTRALDVGAGIGRITEHLLIPAgfKAVDLLDIDQRFLDTARDRLSSTG 108
                             77888**************888788*****************9998655 PP

>> tr|A9V6A5|A9V6A5_MONBE  Predicted protein OS=Monosiga brevicollis OX=81824 GN=10470 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   2.2e-05     0.025      31      75 ..     242     286 ..     230     309 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.2e-05
                             TSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTTTC CS
                  RrnaAD  31 kltvleigpGkGilTeeLakrakqvvvlElderLakllqkklskd 75 
                             +l++le+++G G  T  +   + +v ++E+ + L++  + +l+++
  tr|A9V6A5|A9V6A5_MONBE 242 DLNLLELYSGSGTYTPAMCSVFAHVLSVEIQRTLVEAARRNLELN 286
                             6799*********************************99998843 PP

>> tr|A9UUG3|A9UUG3_MONBE  Predicted protein (Fragment) OS=Monosiga brevicollis OX=81824 GN=15704 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   7.4e-05     0.085      35      86 ..       2      55 ..       1      97 [. 0.81

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 7.4e-05
                            EEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT..TCCCEEEE-S-CC CS
                  RrnaAD 35 leigpGkGilTeeLakrakqvvvlElderLakllqkkls..kdeklkvvhqDfl 86
                            l+ig+G G  Te+L   ++qv   E  +++  +l+ +     +    ++  D l
  tr|A9UUG3|A9UUG3_MONBE  2 LDIGAGDGGVTEQLRPLFDQVETTETNRVMRWRLSRRGYlrVHDEASWMAGDQL 55
                            9***************************99988887533347777777776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (265 nodes)
Target sequences:                         9188  (5511963 residues searched)
Passed MSV filter:                       227  (0.0247061); expected 183.8 (0.02)
Passed bias filter:                      196  (0.0213322); expected 183.8 (0.02)
Passed Vit filter:                        34  (0.00370048); expected 9.2 (0.001)
Passed Fwd filter:                         8  (0.000870701); expected 0.1 (1e-05)
Initial search space (Z):               9188  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.13u 0.01s 00:00:00.14 Elapsed: 00:00:00.05
# Mc/sec: 29213.40
//
[ok]