# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/RrnaAD.hmm.txt
# target sequence database: proteomes/Mus_musculus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: RrnaAD [M=265]
Accession: PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2.2e-65 220.7 0.0 2.7e-65 220.4 0.0 1.1 1 sp|Q9D0D4|DIM1_MOUSE Probable dimethyladenosine transferase
1.9e-41 142.2 0.0 2.4e-41 141.9 0.0 1.1 1 sp|Q8JZM0|TFB1M_MOUSE Dimethyladenosine transferase 1, mitoc
2e-20 73.3 0.0 2.6e-20 72.9 0.0 1.1 1 sp|Q3TL26|TFB2M_MOUSE Dimethyladenosine transferase 2, mitoc
0.0008 18.9 0.0 0.0014 18.1 0.0 1.3 1 sp|Q3U3W5|ANM9_MOUSE Protein arginine N-methyltransferase 9
------ inclusion threshold ------
0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 sp|Q921L7|HEMK1_MOUSE HemK methyltransferase family member 1
Domain annotation for each sequence (and alignments):
>> sp|Q9D0D4|DIM1_MOUSE Probable dimethyladenosine transferase OS=Mus musculus OX=10090 GN=Dimt1 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 220.4 0.0 6e-69 2.7e-65 4 239 .. 30 256 .. 27 278 .. 0.94
Alignments for each domain:
== domain 1 score: 220.4 bits; conditional E-value: 6e-69
CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHH CS
RrnaAD 4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflkfe 89
+++ gq++lkn+ ++n+I+dk+ l++++ vle+gpG+G++T++L++ ak+vv+ Eld+rL+++l k+++ +++kl+v+ D+lk +
sp|Q9D0D4|DIM1_MOUSE 30 FNTGIGQHILKNPLIVNSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQgtpLASKLQVLVGDVLKSD 118
78999*****************************************************************9999*************** PP
HHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCE CS
RrnaAD 90 tpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveksif 178
+p + ++vanlPy+is+++v++ll ++r+ ++ ++l++q+efa rl+a+pg+k+++rls+++++++ v +++kv+k++f
sp|Q9D0D4|DIM1_MOUSE 119 LPFFD----------ACVANLPYQISSPFVFKLL-LHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNF 196
***77..........8******************.788889************************************************ PP
CS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT CS
RrnaAD 179 sPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalss 239
+Pppkv+s++v++e+k+++ p + ++++ +vr+ ++rk+ktls+++ks ++ l++++
sp|Q9D0D4|DIM1_MOUSE 197 RPPPKVESSVVRIEPKNPP-PPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYR 256
******************8.89**************************9888887777654 PP
>> sp|Q8JZM0|TFB1M_MOUSE Dimethyladenosine transferase 1, mitochondrial OS=Mus musculus OX=10090 GN=Tfb1m PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 141.9 0.0 5.3e-45 2.4e-41 5 239 .. 30 278 .. 26 299 .. 0.89
Alignments for each domain:
== domain 1 score: 141.9 bits; conditional E-value: 5.3e-45
XXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT..TCCCEEEE-S-CCGHH CS
RrnaAD 5 rksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls..kdeklkvvhqDflkfe 89
k+++qnfl + + ++I++k+ + v+e+gpG+G T+++++ ++ v+E+d+r++ lq ls +kl +vh D+l+++
sp|Q8JZM0|TFB1M_MOUSE 30 VKQLSQNFLLDLRLTDKIVRKAGSLADVYVYEVGPGPGGITRSILNANvAELLVVEKDTRFIPGLQM-LSdaAPGKLRIVHGDVLTYK 116
5899**************************************9966666******************.5558889***********99 PP
HHHHHCT.....TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHE CS
RrnaAD 90 tpeevte.....kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlreaft 165
+ + + + +++nlP +st+l+ ++le g+ km+l +qke+a+rl+a gsk++srls+++++++
sp|Q8JZM0|TFB1M_MOUSE 117 IEKAFPGnirrqWEDDPPNVHIIGNLPFSVSTPLIIKWLEnislkdgPFVYGRTKMTLTFQKEVAERLVATTGSKQHSRLSIMAQYLC 204
988554478775444556799**********************99885566789********************************** PP
EEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT CS
RrnaAD 166 dvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalss 239
+v+++ +++ ++f P+pkvd +v l++ e+ ++ k e+vv+ ++ +rk l l+p++++ +
sp|Q8JZM0|TFB1M_MOUSE 205 NVEHLFTIPGKAFVPKPKVDVGVVHLTPLIEPKIKQPFKLVEKVVQNAFQFRRKYCHRGLGMLFPEAQRLESTG 278
***************************97775447778999**************************9876644 PP
>> sp|Q3TL26|TFB2M_MOUSE Dimethyladenosine transferase 2, mitochondrial OS=Mus musculus OX=10090 GN=Tfb2m PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 72.9 0.0 5.8e-24 2.6e-20 17 237 .. 82 349 .. 79 377 .. 0.85
Alignments for each domain:
== domain 1 score: 72.9 bits; conditional E-value: 5.8e-24
HHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHHCT....... CS
RrnaAD 17 kvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeevte....... 96
+++ + l++ n++ + +le pG+GilT L+k vv++E+ + ++ +l+ + d+ l+vvh+Df k++ ++ +
sp|Q3TL26|TFB2M_MOUSE 82 NLVRDLLEHQNPSR-QIILECNPGPGILTGALLKAGARVVAFESEKTFIPHLEPLQRnMDGELQVVHCDFFKMDPRYQEVVrpdvssq 168
56667777777764.679*******************************9999955589***************98855558****** PP
...........TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTS.TT-SHHHHHHHHHE CS
RrnaAD 97 ...........kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgs.kkrsrlsvlreaft 165
s + +++v++ lPy+ + ++l+ +r g+v+ + + ++ r+l+a p +++ + vl ++++
sp|Q3TL26|TFB2M_MOUSE 169 aifqnlgikavPWSAGVPIKVFGILPYKHERRILWKILFdlyscesIYRYGRVELNMFVSEKEFRKLIATPKRpDLYQVMAVLWQVAC 256
********9998999******************************99**********************9986368************ PP
EEEEEEEC-GG....................CECS--SSSEEEEEEEE-SS-S.--...S-HHHHHHHHHHHHCTTTSBCCCHCCCTS CS
RrnaAD 166 dvklvakveks....................ifsPppkvdsalvelerkdedl.pq...kdlkkyesvvrkllnrkrktlstslksll 229
dvk++ + s + k ++ lv+++++ + + ++ ++++ + +v++++ +++ ++ l sl
sp|Q3TL26|TFB2M_MOUSE 257 DVKFLHMEPWSsfsvhtenghlekskhgesvN---LLKQNLYLVRMTPRRTLFtENlspLNYDIFFHLVKHCFGKRNAPIIRHLRSLS 341
******999999***99999999988887552...334488*********99877622257899999*************99999987 PP
TCHHHHHC CS
RrnaAD 230 pggelqal 237
+ + l
sp|Q3TL26|TFB2M_MOUSE 342 TVDPINIL 349
76655554 PP
>> sp|Q3U3W5|ANM9_MOUSE Protein arginine N-methyltransferase 9 OS=Mus musculus OX=10090 GN=Prmt9 PE=2 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.1 0.0 3.2e-07 0.0014 17 95 .. 164 246 .. 158 269 .. 0.86
Alignments for each domain:
== domain 1 score: 18.1 bits; conditional E-value: 3.2e-07
HHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHHC CS
RrnaAD 17 kvineIldklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeevt 95
v+n +++k+ + tvl+ig+G+Gil+ +ak a ++v + El + +++l + + ++ +k++h l+ e+p+ +
sp|Q3U3W5|ANM9_MOUSE 164 MVYNAAIQKAVCLGSRTVLDIGTGTGILSM-FAKKAgaQSVYACELSKTMYELACDVVAankMENGIKLLHMKSLDIEIPKHIP 246
699*************************97.56666689*************99997777767777999999999999998654 PP
>> sp|Q921L7|HEMK1_MOUSE HemK methyltransferase family member 1 OS=Mus musculus OX=10090 GN=Hemk1 PE=2 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.6 0.0 7.5e-06 0.033 34 85 .. 164 220 .. 149 228 .. 0.85
Alignments for each domain:
== domain 1 score: 13.6 bits; conditional E-value: 7.5e-06
EEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-C CS
RrnaAD 34 vleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvhqDf 85
+le+g G G+ T +L+ ++ vv++ + e+ + l+ ++ + ++ ++ ++h D+
sp|Q921L7|HEMK1_MOUSE 164 ILEVGCGSGAITLSLLSQLpkSRVVAVDKEEAAVSLTHENAQrlqLQDRIRIIHLDI 220
9******************977899999988777777665555559********998 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (265 nodes)
Target sequences: 22289 (11757923 residues searched)
Passed MSV filter: 594 (0.0266499); expected 445.8 (0.02)
Passed bias filter: 418 (0.0187536); expected 445.8 (0.02)
Passed Vit filter: 56 (0.00251245); expected 22.3 (0.001)
Passed Fwd filter: 5 (0.000224326); expected 0.2 (1e-05)
Initial search space (Z): 22289 [actual number of targets]
Domain search space (domZ): 5 [number of targets reported over threshold]
# CPU time: 0.23u 0.01s 00:00:00.24 Elapsed: 00:00:00.09
# Mc/sec: 34620.55
//
[ok]