# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/RrnaAD.hmm.txt # target sequence database: proteomes/Ornithorhynchus_anatinus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: RrnaAD [M=265] Accession: PF00398.19 Description: Ribosomal RNA adenine dimethylase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.6e-17 62.0 0.0 8.4e-17 61.4 0.0 1.3 1 tr|F6ZKK0|F6ZKK0_ORNAN rRNA adenine N(6)-methyltransferase O 4.7e-11 42.5 0.0 0.0097 15.3 0.0 3.1 3 tr|F6PSD4|F6PSD4_ORNAN Uncharacterized protein OS=Ornithorhy 1.5e-07 31.0 0.0 1.9e-07 30.7 0.0 1.0 1 tr|K7EAF7|K7EAF7_ORNAN rRNA adenine N(6)-methyltransferase O 5.3e-06 26.0 0.0 6.3e-06 25.7 0.0 1.0 1 tr|K7EAG1|K7EAG1_ORNAN rRNA adenine N(6)-methyltransferase O 0.0033 16.8 0.0 0.0054 16.1 0.0 1.3 1 tr|F6VLF6|F6VLF6_ORNAN Methyltransferase like 22 OS=Ornithor ------ inclusion threshold ------ 0.076 12.3 0.0 0.13 11.6 0.0 1.3 1 tr|F6VIV0|F6VIV0_ORNAN Protein arginine methyltransferase 9 0.19 11.0 0.0 0.34 10.2 0.0 1.4 1 tr|F6RR08|F6RR08_ORNAN Uncharacterized protein OS=Ornithorhy Domain annotation for each sequence (and alignments): >> tr|F6ZKK0|F6ZKK0_ORNAN rRNA adenine N(6)-methyltransferase OS=Ornithorhynchus anatinus OX=9258 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 61.4 0.0 2.7e-20 8.4e-17 39 226 .. 11 241 .. 7 278 .. 0.83 Alignments for each domain: == domain 1 score: 61.4 bits; conditional E-value: 2.7e-20 -TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHHCT..................TTCCCCEEEE CS RrnaAD 39 pGkGilTeeLakrakqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeevte..................kdsihqeflv 106 +G+GilT+ L++ vv+lE+d +++ +lq + +d++l+vvh+Df + +e+ + + ++ tr|F6ZKK0|F6ZKK0_ORNAN 11 AGPGILTRALLQTGARVVALESDAAFLPHLQSLKNsLDGQLEVVHCDFFALDCNSEILKppamlsehlfeglgiqevPWTADIPVKI 97 8******************************95558*********************99***************999888899**** PP EEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GG.......... CS RrnaAD 107 vanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveks.......... 176 v+ lP +ll g+ + + l ++ + rl+++p++kk+++lsvl ++++d++l+ + s tr|F6ZKK0|F6ZKK0_ORNAN 98 VGFLPSRREPHTLWRLLYslyqrlsVFSYGRIELNMFLSEKEYTRLVSKPNEKKYQALSVLWQIACDIELLHMEPLSsfvmnsrncv 184 ****99555554555554577675533345677888999999*****************************9999999******987 PP ......CECS--SSSEEEEEEEE-SS-S.--...S-HHHHHHHHHHHHCTTTSBCCCHCC CS RrnaAD 177 ......ifsPppkvdsalvelerkdedl.pq...kdlkkyesvvrkllnrkrktlstslk 226 + sP ++ lv++++++ + + ++ + +v++ +++ + +l +l+ tr|F6ZKK0|F6ZKK0_ORNAN 185 pqkskkVESPS---NLCLVKMTPRKDLFsESltpLNSTFFFHLVKQSFVKHKFKLMDNLN 241 77666544555...66*********98855422246778999999999998888877765 PP >> tr|F6PSD4|F6PSD4_ORNAN Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 8.6 0.0 0.00035 1.1 4 25 .. 24 45 .. 21 52 .. 0.90 2 ! 15.3 0.0 3.1e-06 0.0097 76 127 .. 101 141 .. 95 157 .. 0.84 3 ! 15.2 0.0 3.4e-06 0.01 201 239 .. 218 256 .. 208 278 .. 0.79 Alignments for each domain: == domain 1 score: 8.6 bits; conditional E-value: 0.00035 CXXGCG--EE--HHHHHHHHHH CS RrnaAD 4 lrksygqnflknkkvineIldk 25 +++ gq++lkn+ v+n+I++k tr|F6PSD4|F6PSD4_ORNAN 24 FNTGIGQHILKNPLVVNSIVEK 45 78999***************98 PP == domain 2 score: 15.3 bits; conditional E-value: 3.1e-06 CCEEEE-S-CCGHHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGG CS RrnaAD 76 eklkvvhqDflkfetpeevtekdsihqeflvvanlPyeistqlvkqlleesr 127 +kl+v+ D+lk+e+p + ++vanlP +is+++v++ll +r tr|F6PSD4|F6PSD4_ORNAN 101 GKLQVLVGDVLKTELPFFD----------ACVANLPFQISSPFVFKLLL-HR 141 7899999999999999977..........8*****************95.43 PP == domain 3 score: 15.2 bits; conditional E-value: 3.4e-06 S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT CS RrnaAD 201 kdlkkyesvvrkllnrkrktlstslksllpggelqalss 239 ++++++ +vr+ ++rk+ktls+++ks ++ l++++ tr|F6PSD4|F6PSD4_ORNAN 218 NQIQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYR 256 6799**********************9888888777754 PP >> tr|K7EAF7|K7EAF7_ORNAN rRNA adenine N(6)-methyltransferase OS=Ornithorhynchus anatinus OX=9258 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.7 0.0 6e-11 1.9e-07 76 143 .. 8 87 .. 2 92 .. 0.90 Alignments for each domain: == domain 1 score: 30.7 bits; conditional E-value: 6e-11 CCEEEE-S-CCGHHHHHHHCT.....TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHH CS RrnaAD 76 eklkvvhqDflkfetpeevte.....kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefar 143 +kl +vh D+l+f++ + d + ++ +++nlP +st+l+ ++le + g+ +m+l +qke+a+ tr|K7EAF7|K7EAF7_ORNAN 8 GKLRIVHGDVLTFNVEKAFPRslrreWDADPPNIHIIGNLPFSVSTPLIIKWLEnisrkdgPFIYGRTQMTLTFQKEVAE 87 6899*************7776898887888899***********************999987788999**********97 PP >> tr|K7EAG1|K7EAG1_ORNAN rRNA adenine N(6)-methyltransferase OS=Ornithorhynchus anatinus OX=9258 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.0 2e-09 6.3e-06 3 43 .. 28 68 .. 26 71 .. 0.95 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 2e-09 CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTC CS RrnaAD 3 klrksygqnflknkkvineIldklnleekltvleigpGkGi 43 ++rk+++qnfl + + ++I++k+ ++ v+e+gpG+G tr|K7EAG1|K7EAG1_ORNAN 28 RARKQLSQNFLLDLRLTDKIVRKAGDLKNAYVYEVGPGPGX 68 789************************************96 PP >> tr|F6VLF6|F6VLF6_ORNAN Methyltransferase like 22 OS=Ornithorhynchus anatinus OX=9258 GN=METTL22 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 1.7e-06 0.0054 19 121 .. 187 309 .. 184 336 .. 0.67 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 1.7e-06 HHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..........SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHHC CS RrnaAD 19 ineIldklnleekltvleigpGkGilTeeLakra..........kqvvvlElderLakllqkklskdeklkvvhqDflkfetpeevt 95 ++ Il k++l ++ tvle+g+G+Gi++ + a + +v+ E L k+l++ +k++ +kv + D lk + + + tr|F6VLF6|F6VLF6_ORNAN 187 ADYILFKSDLFKNCTVLELGAGTGITSIIAGTVAktvyctdvgeDLLVMCERNVTLNKHLTE--EKGGTIKVRELDWLKDGLCTDPQ 271 678999********************988776661113333333334555555555555555..57888888877777766666554 PP T..........TTCCCCEEEEEEE--T..TTHHHHHHH CS RrnaAD 96 e..........kdsihqeflvvanlPy..eistqlvkq 121 + +++h ++a + y ++ +l+k tr|F6VLF6|F6VLF6_ORNAN 272 VpyswseeeiaDLHDHTTVVFAADVFYddDLTDALFKT 309 46666667777777777777777777755555555555 PP >> tr|F6VIV0|F6VIV0_ORNAN Protein arginine methyltransferase 9 OS=Ornithorhynchus anatinus OX=9258 GN=PRMT9 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 4.2e-05 0.13 24 94 .. 141 215 .. 129 240 .. 0.83 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 4.2e-05 HHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHH CS RrnaAD 24 dklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeev 94 +k+ +tvl+ig+G+Gil+ +ak a +v + El + +++l + + ++ +k++h l+ e+p+ + tr|F6VIV0|F6VIV0_ORNAN 141 QKVVSLGCKTVLDIGTGTGILSM-FAKKAgaPSVYACELSKTMYELACDVVAannMATEIKLLHMKSLDIEVPKHL 215 5555556689***********97.56666589**************999887777889999999999999999966 PP >> tr|F6RR08|F6RR08_ORNAN Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 0.00011 0.34 25 71 .. 101 148 .. 84 166 .. 0.85 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.00011 HH-GG.TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCH CS RrnaAD 25 klnle.ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkk 71 k+n+ ++ +l++g+G G T+++ +++ + El e ++ lqkk tr|F6RR08|F6RR08_ORNAN 101 KINPDwKTHRLLDLGAGDGEVTKIMSPHFEEIYATELSETMIWQLQKK 148 6788889999*********************************99994 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 21677 (8259262 residues searched) Passed MSV filter: 536 (0.0247267); expected 433.5 (0.02) Passed bias filter: 367 (0.0169304); expected 433.5 (0.02) Passed Vit filter: 45 (0.00207593); expected 21.7 (0.001) Passed Fwd filter: 7 (0.000322923); expected 0.2 (1e-05) Initial search space (Z): 21677 [actual number of targets] Domain search space (domZ): 7 [number of targets reported over threshold] # CPU time: 0.16u 0.01s 00:00:00.17 Elapsed: 00:00:00.06 # Mc/sec: 36478.41 // [ok]