# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/RrnaAD.hmm.txt
# target sequence database:        proteomes/Ornithorhynchus_anatinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       RrnaAD  [M=265]
Accession:   PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    5.6e-17   62.0   0.0    8.4e-17   61.4   0.0    1.3  1  tr|F6ZKK0|F6ZKK0_ORNAN  rRNA adenine N(6)-methyltransferase O
    4.7e-11   42.5   0.0     0.0097   15.3   0.0    3.1  3  tr|F6PSD4|F6PSD4_ORNAN  Uncharacterized protein OS=Ornithorhy
    1.5e-07   31.0   0.0    1.9e-07   30.7   0.0    1.0  1  tr|K7EAF7|K7EAF7_ORNAN  rRNA adenine N(6)-methyltransferase O
    5.3e-06   26.0   0.0    6.3e-06   25.7   0.0    1.0  1  tr|K7EAG1|K7EAG1_ORNAN  rRNA adenine N(6)-methyltransferase O
     0.0033   16.8   0.0     0.0054   16.1   0.0    1.3  1  tr|F6VLF6|F6VLF6_ORNAN  Methyltransferase like 22 OS=Ornithor
  ------ inclusion threshold ------
      0.076   12.3   0.0       0.13   11.6   0.0    1.3  1  tr|F6VIV0|F6VIV0_ORNAN  Protein arginine methyltransferase 9 
       0.19   11.0   0.0       0.34   10.2   0.0    1.4  1  tr|F6RR08|F6RR08_ORNAN  Uncharacterized protein OS=Ornithorhy


Domain annotation for each sequence (and alignments):
>> tr|F6ZKK0|F6ZKK0_ORNAN  rRNA adenine N(6)-methyltransferase OS=Ornithorhynchus anatinus OX=9258 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.4   0.0   2.7e-20   8.4e-17      39     226 ..      11     241 ..       7     278 .. 0.83

  Alignments for each domain:
  == domain 1  score: 61.4 bits;  conditional E-value: 2.7e-20
                             -TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHHCT..................TTCCCCEEEE CS
                  RrnaAD  39 pGkGilTeeLakrakqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeevte..................kdsihqeflv 106
                             +G+GilT+ L++    vv+lE+d +++ +lq   + +d++l+vvh+Df   +  +e+ +                        + ++
  tr|F6ZKK0|F6ZKK0_ORNAN  11 AGPGILTRALLQTGARVVALESDAAFLPHLQSLKNsLDGQLEVVHCDFFALDCNSEILKppamlsehlfeglgiqevPWTADIPVKI 97 
                             8******************************95558*********************99***************999888899**** PP

                             EEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GG.......... CS
                  RrnaAD 107 vanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveks.......... 176
                             v+ lP         +ll            g+ +  + l ++ + rl+++p++kk+++lsvl ++++d++l+   + s          
  tr|F6ZKK0|F6ZKK0_ORNAN  98 VGFLPSRREPHTLWRLLYslyqrlsVFSYGRIELNMFLSEKEYTRLVSKPNEKKYQALSVLWQIACDIELLHMEPLSsfvmnsrncv 184
                             ****99555554555554577675533345677888999999*****************************9999999******987 PP

                             ......CECS--SSSEEEEEEEE-SS-S.--...S-HHHHHHHHHHHHCTTTSBCCCHCC CS
                  RrnaAD 177 ......ifsPppkvdsalvelerkdedl.pq...kdlkkyesvvrkllnrkrktlstslk 226
                                   + sP    ++ lv++++++  + +    ++   +  +v++ +++ + +l  +l+
  tr|F6ZKK0|F6ZKK0_ORNAN 185 pqkskkVESPS---NLCLVKMTPRKDLFsESltpLNSTFFFHLVKQSFVKHKFKLMDNLN 241
                             77666544555...66*********98855422246778999999999998888877765 PP

>> tr|F6PSD4|F6PSD4_ORNAN  Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.0   0.00035       1.1       4      25 ..      24      45 ..      21      52 .. 0.90
   2 !   15.3   0.0   3.1e-06    0.0097      76     127 ..     101     141 ..      95     157 .. 0.84
   3 !   15.2   0.0   3.4e-06      0.01     201     239 ..     218     256 ..     208     278 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00035
                            CXXGCG--EE--HHHHHHHHHH CS
                  RrnaAD  4 lrksygqnflknkkvineIldk 25
                            +++  gq++lkn+ v+n+I++k
  tr|F6PSD4|F6PSD4_ORNAN 24 FNTGIGQHILKNPLVVNSIVEK 45
                            78999***************98 PP

  == domain 2  score: 15.3 bits;  conditional E-value: 3.1e-06
                             CCEEEE-S-CCGHHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGG CS
                  RrnaAD  76 eklkvvhqDflkfetpeevtekdsihqeflvvanlPyeistqlvkqlleesr 127
                             +kl+v+  D+lk+e+p +           ++vanlP +is+++v++ll  +r
  tr|F6PSD4|F6PSD4_ORNAN 101 GKLQVLVGDVLKTELPFFD----------ACVANLPFQISSPFVFKLLL-HR 141
                             7899999999999999977..........8*****************95.43 PP

  == domain 3  score: 15.2 bits;  conditional E-value: 3.4e-06
                             S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT CS
                  RrnaAD 201 kdlkkyesvvrkllnrkrktlstslksllpggelqalss 239
                              ++++++ +vr+ ++rk+ktls+++ks   ++ l++++ 
  tr|F6PSD4|F6PSD4_ORNAN 218 NQIQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYR 256
                             6799**********************9888888777754 PP

>> tr|K7EAF7|K7EAF7_ORNAN  rRNA adenine N(6)-methyltransferase OS=Ornithorhynchus anatinus OX=9258 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.7   0.0     6e-11   1.9e-07      76     143 ..       8      87 ..       2      92 .. 0.90

  Alignments for each domain:
  == domain 1  score: 30.7 bits;  conditional E-value: 6e-11
                             CCEEEE-S-CCGHHHHHHHCT.....TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHH CS
                  RrnaAD  76 eklkvvhqDflkfetpeevte.....kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefar 143
                             +kl +vh D+l+f++ +          d +  ++ +++nlP  +st+l+ ++le         + g+ +m+l +qke+a+
  tr|K7EAF7|K7EAF7_ORNAN   8 GKLRIVHGDVLTFNVEKAFPRslrreWDADPPNIHIIGNLPFSVSTPLIIKWLEnisrkdgPFIYGRTQMTLTFQKEVAE 87 
                             6899*************7776898887888899***********************999987788999**********97 PP

>> tr|K7EAG1|K7EAG1_ORNAN  rRNA adenine N(6)-methyltransferase OS=Ornithorhynchus anatinus OX=9258 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.0     2e-09   6.3e-06       3      43 ..      28      68 ..      26      71 .. 0.95

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 2e-09
                            CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTC CS
                  RrnaAD  3 klrksygqnflknkkvineIldklnleekltvleigpGkGi 43
                            ++rk+++qnfl +  + ++I++k+   ++  v+e+gpG+G 
  tr|K7EAG1|K7EAG1_ORNAN 28 RARKQLSQNFLLDLRLTDKIVRKAGDLKNAYVYEVGPGPGX 68
                            789************************************96 PP

>> tr|F6VLF6|F6VLF6_ORNAN  Methyltransferase like 22 OS=Ornithorhynchus anatinus OX=9258 GN=METTL22 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   1.7e-06    0.0054      19     121 ..     187     309 ..     184     336 .. 0.67

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1.7e-06
                             HHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..........SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHHC CS
                  RrnaAD  19 ineIldklnleekltvleigpGkGilTeeLakra..........kqvvvlElderLakllqkklskdeklkvvhqDflkfetpeevt 95 
                             ++ Il k++l ++ tvle+g+G+Gi++ +    a          + +v+ E    L k+l++  +k++ +kv + D lk  +  + +
  tr|F6VLF6|F6VLF6_ORNAN 187 ADYILFKSDLFKNCTVLELGAGTGITSIIAGTVAktvyctdvgeDLLVMCERNVTLNKHLTE--EKGGTIKVRELDWLKDGLCTDPQ 271
                             678999********************988776661113333333334555555555555555..57888888877777766666554 PP

                             T..........TTCCCCEEEEEEE--T..TTHHHHHHH CS
                  RrnaAD  96 e..........kdsihqeflvvanlPy..eistqlvkq 121
                             +           +++h    ++a + y   ++ +l+k 
  tr|F6VLF6|F6VLF6_ORNAN 272 VpyswseeeiaDLHDHTTVVFAADVFYddDLTDALFKT 309
                             46666667777777777777777777755555555555 PP

>> tr|F6VIV0|F6VIV0_ORNAN  Protein arginine methyltransferase 9 OS=Ornithorhynchus anatinus OX=9258 GN=PRMT9 PE=3 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   4.2e-05      0.13      24      94 ..     141     215 ..     129     240 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 4.2e-05
                             HHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHH CS
                  RrnaAD  24 dklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeev 94 
                             +k+     +tvl+ig+G+Gil+  +ak a   +v + El + +++l  + +     ++ +k++h   l+ e+p+ +
  tr|F6VIV0|F6VIV0_ORNAN 141 QKVVSLGCKTVLDIGTGTGILSM-FAKKAgaPSVYACELSKTMYELACDVVAannMATEIKLLHMKSLDIEVPKHL 215
                             5555556689***********97.56666589**************999887777889999999999999999966 PP

>> tr|F6RR08|F6RR08_ORNAN  Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   0.00011      0.34      25      71 ..     101     148 ..      84     166 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00011
                             HH-GG.TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCH CS
                  RrnaAD  25 klnle.ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkk 71 
                             k+n+  ++  +l++g+G G  T+++   +++  + El e ++  lqkk
  tr|F6RR08|F6RR08_ORNAN 101 KINPDwKTHRLLDLGAGDGEVTKIMSPHFEEIYATELSETMIWQLQKK 148
                             6788889999*********************************99994 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (265 nodes)
Target sequences:                        21677  (8259262 residues searched)
Passed MSV filter:                       536  (0.0247267); expected 433.5 (0.02)
Passed bias filter:                      367  (0.0169304); expected 433.5 (0.02)
Passed Vit filter:                        45  (0.00207593); expected 21.7 (0.001)
Passed Fwd filter:                         7  (0.000322923); expected 0.2 (1e-05)
Initial search space (Z):              21677  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.16u 0.01s 00:00:00.17 Elapsed: 00:00:00.06
# Mc/sec: 36478.41
//
[ok]