# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/RrnaAD.hmm.txt
# target sequence database: proteomes/Petromyzon_marinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: RrnaAD [M=265]
Accession: PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
4.9e-25 87.7 0.0 6.2e-25 87.4 0.0 1.0 1 tr|S4RSM5|S4RSM5_PETMA rRNA adenine N(6)-methyltransferase O
3.3e-18 65.3 0.0 4.1e-18 65.0 0.0 1.0 1 tr|S4RUG9|S4RUG9_PETMA rRNA adenine N(6)-methyltransferase O
3.7e-11 42.2 0.0 7.9e-09 34.6 0.0 2.2 2 tr|S4R4I3|S4R4I3_PETMA Phosphoethanolamine methyltransferase
8.9e-08 31.1 0.0 7.1e-07 28.2 0.0 2.1 2 tr|S4RMG0|S4RMG0_PETMA Phosphoethanolamine methyltransferase
0.00073 18.3 0.0 0.0012 17.6 0.0 1.2 1 tr|S4RWE3|S4RWE3_PETMA Acetylserotonin O-methyltransferase O
------ inclusion threshold ------
0.083 11.5 0.0 0.12 11.0 0.0 1.2 1 tr|S4R939|S4R939_PETMA Methyltransferase like 9 OS=Petromyzo
0.14 10.8 0.0 0.2 10.3 0.0 1.1 1 tr|S4RA41|S4RA41_PETMA Acetylserotonin O-methyltransferase O
Domain annotation for each sequence (and alignments):
>> tr|S4RSM5|S4RSM5_PETMA rRNA adenine N(6)-methyltransferase OS=Petromyzon marinus OX=7757 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 87.4 0.0 3.2e-28 6.2e-25 12 263 .. 6 304 .. 2 306 .. 0.90
Alignments for each domain:
== domain 1 score: 87.4 bits; conditional E-value: 3.2e-28
EE--HHHHHHHHHHH-GG..TTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHH CS
RrnaAD 12 flknkkvineIldklnle..ekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeev 94
f++++ v+ +I ++l+++ ++ v + +G+GilT+ L++ + vvvlE d+ ++ +lq+ + ++++++ h+D+ k +t +
tr|S4RSM5|S4RSM5_PETMA 6 FITEPRVAHSITEALQINegDQAVVFDCSAGPGILTRALLNSGaNRVVVLERDKLFLPPLQELEEsAEGRMNLFHCDVFKLDTHDGL 92
999***************6667789**************66655******************5558999****************99 PP
CT..................TTCCCCEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SH CS
RrnaAD 95 te..................kdsihqeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsr 156
+ +++ +++ v+ lP + +l+ rfg+v+ l + + +++ ++pg k++s+
tr|S4RSM5|S4RSM5_PETMA 93 LRppfmsskqlqvqlglkerSWNDEIPIRLVGILPLRNPRTILWRLIYaafqgisVFRFGRVELNLFISERELQKIRSSPGCKNYSS 179
99****************99999999**********999999999998899999999****************************** PP
HHHHHHHHEEEEEEEEC-GG................CECS--SSSEEEEEEEE-SS..-S.--S-HHHHHHHHHHHHCTTTSBCCCH CS
RrnaAD 157 lsvlreaftdvklvakveks................ifsPppkvdsalvelerkde..dl.pqkdlkkyesvvrkllnrkrktlsts 224
ls+l +++ d+++v++ + + + +++ l++l+++ e ++ + +++++ ++++++l r+rk+l+
tr|S4RSM5|S4RSM5_PETMA 180 LSILWQIMSDITVVYQESLTsvvtcsnkalktdffsNHVEA-GEKLCLMQLNPRREitSVlNYHSMDRFMAMINHCLSRRRKKLKDI 265
**************9987779***********977543344.7899********98223455667899*****************99 PP
CCCTSTCHHHHHCTT..T--TTTCCCCSGHHHHHHHHHHH CS
RrnaAD 225 lksllpggelqalsst.gindnalvkklsaeqtldifkel 263
l+ l + g +++ + g+ +a+ + +s+ ++l++f+++
tr|S4RSM5|S4RSM5_PETMA 266 LN-LWNPGSGELIMAQlGLSPEATSGTVSPRDYLRLFEII 304
88.55555556666777********************998 PP
>> tr|S4RUG9|S4RUG9_PETMA rRNA adenine N(6)-methyltransferase OS=Petromyzon marinus OX=7757 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 65.0 0.0 2.1e-21 4.1e-18 104 242 .. 5 151 .. 2 169 .. 0.90
Alignments for each domain:
== domain 1 score: 65.0 bits; conditional E-value: 2.1e-21
EEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH.--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCECS-- CS
RrnaAD 104 flvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrll.arpgskkrsrlsvlreaftdvklvakveksifsPpp 182
+ +++nlP +st+lv +le g+ + +l +qke+a+rll a+ s++r+rlsv+++ + +vkl +++ s+f P p
tr|S4RUG9|S4RUG9_PETMA 5 IHIIGNLPFSVSTALVIDWLEcmanrsgPFSYGRTRLTLTFQKEVAERLLvASVHSSQRCRLSVMAQSLSSVKLRFIIPGSAFIPVP 91
689********************999884445689*************7548999******************************** PP
SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T- CS
RrnaAD 183 kvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalsstgi 242
kvd +v le+ ++ q+ + e+vvr l+ +rk + l+p++e+ +ls++ +
tr|S4RUG9|S4RUG9_PETMA 92 KVDVGVVTLEPLVTPRIQQPFPLVEKVVRSLFQFRRKYCLRGVELLFPQAERLSLSQRML 151
***********988657999*******************************999987643 PP
>> tr|S4R4I3|S4R4I3_PETMA Phosphoethanolamine methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 34.6 0.0 4.1e-12 7.9e-09 30 95 .. 50 115 .. 36 138 .. 0.89
2 ! 5.3 0.0 0.0034 6.6 19 104 .. 272 367 .. 266 371 .. 0.73
Alignments for each domain:
== domain 1 score: 34.6 bits; conditional E-value: 4.1e-12
TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHHC CS
RrnaAD 30 ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkklskdeklkvvhqDflkfetpeevt 95
++ +vle+g+G G +T +Lak+a++v+++ + ++ ++ s++ ++k +++D+ + ++pe+
tr|S4R4I3|S4R4I3_PETMA 50 DDAKVLELGAGIGRFTGHLAKQARHVTAVDFMQTFLDKNRELNSDHVNIKFLQADVTQLQFPENSF 115
6789*************************************888******************9754 PP
== domain 2 score: 5.3 bits; conditional E-value: 0.0034
HHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTTTCCCEEE..E-S-CCGHHHHHHHCT...... CS
RrnaAD 19 ineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkklskdeklkv..vhqDflkfetpeevte...... 96
+e ++ l+l+ ++vl++g G G +ak + v + l ++++++ ++ ++d+ l v D+ k ++pee +
tr|S4R4I3|S4R4I3_PETMA 272 TKEFVSLLDLQAGQKVLDVGCGIGGGNFYMAKAFkVDVLGMDLSSNMVEIAMERATEDSTLLVqfEISDATKRDFPEESFDvvysrd 358
67788899****************999999999944566678888888888888887666655424568888888876666666655 PP
.TTCCCCEE CS
RrnaAD 97 .kdsihqef 104
++i ++f
tr|S4R4I3|S4R4I3_PETMA 359 tILHIADKF 367
555555555 PP
>> tr|S4RMG0|S4RMG0_PETMA Phosphoethanolamine methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 28.2 0.0 3.7e-10 7.1e-07 30 95 .. 47 112 .. 36 134 .. 0.86
2 ? -0.0 0.0 0.15 2.9e+02 21 42 .. 272 293 .. 266 295 .. 0.83
Alignments for each domain:
== domain 1 score: 28.2 bits; conditional E-value: 3.7e-10
TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHHC CS
RrnaAD 30 ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkklskdeklkvvhqDflkfetpeevt 95
+ + +le+g+G G +T +Lak+a++v+++ e++++ ++ ++l+ +++D+ + ++p +
tr|S4RMG0|S4RMG0_PETMA 47 DGTDILELGAGIGRFTGHLAKIANHVTAVDFMENFIAKNKEDNGHRGNLTFLQADVTQLDFPANSF 112
5678*************************************8889*****************9765 PP
== domain 2 score: -0.0 bits; conditional E-value: 0.15
HHHHHH-GGTTSEEEEES-TTT CS
RrnaAD 21 eIldklnleekltvleigpGkG 42
e l l l++ ++vl++g G G
tr|S4RMG0|S4RMG0_PETMA 272 EFLAMLGLRQGQKVLDVGCGIG 293
5667788999**********98 PP
>> tr|S4RWE3|S4RWE3_PETMA Acetylserotonin O-methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.6 0.0 6.2e-07 0.0012 22 92 .. 177 248 .. 175 275 .. 0.87
Alignments for each domain:
== domain 1 score: 17.6 bits; conditional E-value: 6.2e-07
HHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHH CS
RrnaAD 22 IldklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkklskdeklkvvhqDflkfetpe 92
Il++ +l+ + v ++g G+G+l +++a + v+++ l ++ +++ qk++ +++++k+ Df k ++pe
tr|S4RWE3|S4RWE3_PETMA 177 ILNAFDLSSFKDVCDVGGGTGVLAQQFARMYpdARVTLFDL-PEVLEVAQKHFLSSGNVKLHAGDFFKGKIPE 248
8999999999*********************9666666665.666799*******************998887 PP
>> tr|S4R939|S4R939_PETMA Methyltransferase like 9 OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.0 0.0 6.1e-05 0.12 32 71 .. 148 187 .. 130 208 .. 0.90
Alignments for each domain:
== domain 1 score: 11.0 bits; conditional E-value: 6.1e-05
SEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCH CS
RrnaAD 32 ltvleigpGkGilTeeLakrakqvvvlElderLakllqkk 71
+ +l++g+G G T+++ +kqv v E + + +l+k+
tr|S4R939|S4R939_PETMA 148 DSLLDLGAGDGEVTAIMGAHFKQVFVTEVSPTMQWRLRKR 187
789***************************9999999984 PP
>> tr|S4RA41|S4RA41_PETMA Acetylserotonin O-methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.3 0.0 0.0001 0.2 22 122 .. 181 273 .. 178 280 .. 0.81
Alignments for each domain:
== domain 1 score: 10.3 bits; conditional E-value: 0.0001
HHHHH-GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHHCTTTCCCCEEEE CS
RrnaAD 22 IldklnleekltvleigpGkGilTeeLakra..kqvvvlElderLakllqkklskdeklkvvhqDflkfetpeevtekdsihqeflv 106
+l + +l++ + v+++g +G+l +La++ v+v+ + + +++ +k++ ++ +++ Df k e+p+ + +
tr|S4RA41|S4RA41_PETMA 181 VLTAFDLSPFKDVYDLGGCTGALALQLAEIHpdSRVTVF-DLPPVVEVARKHFLASGTVQLQGGDFFKDEIPQ---------GDLYI 257
5778899999**********************5555555.557789**********************99998.........45566 PP
EEE--TTTHHHHHHHH CS
RrnaAD 107 vanlPyeistqlvkql 122
a + + s++ +ql
tr|S4RA41|S4RA41_PETMA 258 LARILHDWSKEQCMQL 273
6666666655555555 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (265 nodes)
Target sequences: 13539 (5048892 residues searched)
Passed MSV filter: 344 (0.0254081); expected 270.8 (0.02)
Passed bias filter: 273 (0.020164); expected 270.8 (0.02)
Passed Vit filter: 32 (0.00236354); expected 13.5 (0.001)
Passed Fwd filter: 7 (0.000517025); expected 0.1 (1e-05)
Initial search space (Z): 13539 [actual number of targets]
Domain search space (domZ): 7 [number of targets reported over threshold]
# CPU time: 0.12u 0.01s 00:00:00.13 Elapsed: 00:00:00.04
# Mc/sec: 33448.91
//
[ok]