# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/RrnaAD.hmm.txt
# target sequence database: proteomes/Tetrahymena_thermophila.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: RrnaAD [M=265]
Accession: PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
6.4e-62 209.6 0.5 9.2e-62 209.1 0.5 1.2 1 tr|Q24GH8|Q24GH8_TETTS rRNA adenine N(6)-methyltransferase O
3.3e-05 23.7 0.3 5.2e-05 23.0 0.0 1.4 2 tr|Q24E29|Q24E29_TETTS UbiE/COQ5 family methyltransferase OS
0.0023 17.6 0.1 0.0052 16.5 0.1 1.7 1 tr|W7XCF3|W7XCF3_TETTS HemK methyltransferase family protein
0.0032 17.2 0.0 0.0042 16.8 0.0 1.2 1 tr|I7M351|I7M351_TETTS Kinase domain protein OS=Tetrahymena
0.0044 16.7 0.0 0.0058 16.3 0.0 1.2 1 tr|I7LWQ0|I7LWQ0_TETTS Kinase domain protein OS=Tetrahymena
0.0097 15.6 0.0 0.015 15.0 0.0 1.3 1 tr|I7MAE9|I7MAE9_TETTS UbiE/COQ5 family methyltransferase OS
------ inclusion threshold ------
0.011 15.5 0.1 0.018 14.7 0.1 1.4 1 tr|I7MKV3|I7MKV3_TETTS Arginine N-methyltransferase OS=Tetra
0.02 14.6 0.1 0.025 14.3 0.1 1.3 1 tr|Q239D4|Q239D4_TETTS Cyclopropane-fatty-acyl-phospholipid
0.021 14.5 0.2 0.031 13.9 0.2 1.2 1 tr|Q22R62|Q22R62_TETTS Oxidoreductase, short chain dehydroge
0.079 12.6 0.2 0.2 11.3 0.0 1.7 2 tr|Q22D66|Q22D66_TETTS UbiE/COQ5 methyltransferase OS=Tetrah
0.097 12.3 0.0 0.11 12.1 0.0 1.2 1 tr|Q24D56|Q24D56_TETTS UbiE/COQ5 methyltransferase, putative
0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 tr|I7MB26|I7MB26_TETTS Spermine/spermidine synthase OS=Tetra
Domain annotation for each sequence (and alignments):
>> tr|Q24GH8|Q24GH8_TETTS rRNA adenine N(6)-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TT
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 209.1 0.5 4.1e-65 9.2e-62 4 240 .. 13 240 .. 10 259 .. 0.95
Alignments for each domain:
== domain 1 score: 209.1 bits; conditional E-value: 4.1e-65
CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS
RrnaAD 4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87
++ks+gq++l+n++++ +I++k+ +++++ vleigpG+G+lT+ L++ ak+v ++E+d+r++++l+k+++ ++k ++++ D+
tr|Q24GH8|Q24GH8_TETTS 13 FNKSFGQHILVNPQMLHSIVEKSAIRPTDIVLEIGPGTGNLTALLLEKAKKVIAVEIDPRMVAELNKRFKysqHAHKFELIQGDAIS 99
79********************************************************************99999************ PP
HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC- CS
RrnaAD 88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakve 174
+e+p + +van+Py+is++lv++ll+ +r+ ++ ++l++qkefa r +a+p+s +++rlsv+++++ ++ kv+
tr|Q24GH8|Q24GH8_TETTS 100 TEFPFFD----------VCVANTPYQISSPLVFKLLS-HRPLFRHAVLMFQKEFAMRCVAKPSSDLYCRLSVNVQLLSKCDHLIKVG 175
*****77..........7******************7.88889******************************************** PP
GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT. CS
RrnaAD 175 ksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalsst 240
k++f+Pppkv+s+++++e+k++ p++++ +++ ++r ++ rk+k+ls+ +k++ + l+++ +t
tr|Q24GH8|Q24GH8_TETTS 176 KNNFKPPPKVESSVIRIEPKNPA-PVLNYIEWDGLLRVCFMRKNKQLSAIFKNKSVLQVLEKNFET 240
**********************8.8***************************99888888877665 PP
>> tr|Q24E29|Q24E29_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 23.0 0.0 2.3e-08 5.2e-05 24 124 .. 36 142 .. 25 158 .. 0.75
2 ? -3.3 0.0 2.5 5.7e+03 225 239 .. 229 243 .. 195 256 .. 0.51
Alignments for each domain:
== domain 1 score: 23.0 bits; conditional E-value: 2.3e-08
HHH-GGTTSEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHHCTTTCCCCE.E. CS
RrnaAD 24 dklnleekltvleigpGkGilTeeLakra...kqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeevtekdsihqe.f. 104
+ l++ + + +le+g+G+G+l ++++++ ++v+ + e+++++++k+l+ +++ +v + + ++ + + e++ +qe f
tr|Q24E29|Q24E29_TETTS 36 NMLKIDKRDSILEVGAGTGFLYNHILNYKkqtAKYVATDISEKMLQIMSKRLKlEYKENQVNNYEKYNLTIQKANAEQLPFEQEsFd 122
5577889******************9999666789*****************98777777777777777777655554443333141 PP
EEEEE--TTTHHHHHHHHHH CS
RrnaAD 105 lvvanlPyeistqlvkqlle 124
++nl +i+ + vk l e
tr|Q24E29|Q24E29_TETTS 123 CLIGNLCLHITPDPVKMLSE 142
34677777777666665555 PP
== domain 2 score: -3.3 bits; conditional E-value: 2.5
CCCTSTCHHHHHCTT CS
RrnaAD 225 lksllpggelqalss 239
l + ++++ +++++
tr|Q24E29|Q24E29_TETTS 229 LGTYYSEEIKNKVIE 243
333333333333322 PP
>> tr|W7XCF3|W7XCF3_TETTS HemK methyltransferase family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.5 0.1 2.3e-06 0.0052 23 117 .. 107 206 .. 98 270 .. 0.74
Alignments for each domain:
== domain 1 score: 16.5 bits; conditional E-value: 2.3e-06
HHHH-GG.TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-H.HHHHHHHCHTT.....TCCCEEEE-S-CCGHHHHHHHCTTTCCCC CS
RrnaAD 23 ldklnle.ekltvleigpGkGilTeeLakrakqvvvlElde.rLakllqkkls.....kdeklkvvhqDflkfetpeevtekdsihq 102
++kl + +k + leig G+G+ + +L+k q++ + +d+ +++ +l k+ + ++l+++h + lkf + +++ q
tr|W7XCF3|W7XCF3_TETTS 107 VNKLSKQkQKCQFLEIGIGTGAISLSLLKENSQFTGIAIDKqKFCIELAKQNLnlnkiDPQRLQLIHLECLKFFQNNLN---QNPDQ 190
5665555578899***********************9999526887776654448888899***********9666633...34444 PP
EE.EEEEE--TTTHHH CS
RrnaAD 103 ef.lvvanlPyeistq 117
+f +v+n Py ++q
tr|W7XCF3|W7XCF3_TETTS 191 QFdFIVSNPPYIPTSQ 206
4413466666644444 PP
>> tr|I7M351|I7M351_TETTS Kinase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00558360
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.8 0.0 1.9e-06 0.0042 28 93 .. 38 105 .. 28 136 .. 0.88
Alignments for each domain:
== domain 1 score: 16.8 bits; conditional E-value: 1.9e-06
GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHH CS
RrnaAD 28 leekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpee 93
++++ ++l +g+G l+ee+++ ++ + + + + k++q+k + k+++ k ++ D+ ++e+ +
tr|I7M351|I7M351_TETTS 38 INPESKILNVGSGSSRLSEEMFDEGhQNITNIDISSIVTKSMQEKYKdKGPNFKYLQMDVRNMEFEAK 105
56899****************99888*********************99*************999875 PP
>> tr|I7LWQ0|I7LWQ0_TETTS Kinase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00578720
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.3 0.0 2.6e-06 0.0058 30 96 .. 40 108 .. 30 151 .. 0.85
Alignments for each domain:
== domain 1 score: 16.3 bits; conditional E-value: 2.6e-06
TTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHHHHHHHCT CS
RrnaAD 30 ekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls.kdeklkvvhqDflkfetpeevte 96
++ ++l ig+G ++ee+++ ++ + + + ++ k +q+k + k++++k + D+ ++++p ++
tr|I7LWQ0|I7LWQ0_TETTS 40 PESKILNIGAGNSRMSEEMFDEGyQNITNIDISQVVTKAMQEKYKdKGPNMKYLCMDVKNMDFPAGSYD 108
7899***************88887*********************999***************997766 PP
>> tr|I7MAE9|I7MAE9_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.0 0.0 6.5e-06 0.015 32 93 .. 53 117 .. 35 162 .. 0.89
Alignments for each domain:
== domain 1 score: 15.0 bits; conditional E-value: 6.5e-06
SEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHH CS
RrnaAD 32 ltvleigpGkGilTeeLakra...kqvvvlElderLakllqkklskdeklkvvhqDflkfetpee 93
+ +l++g G+G+ ++ +r+ qv+ + +d++ + +k +sk++++++ +f+++e +
tr|I7MAE9|I7MAE9_TETTS 53 KRILDVGVGTGHPLYSIIDRIpksVQVTGIDIDTNYIPAAKKIFSKHSNVEIKYMNFYDMEKEKT 117
689******************97678999*****************************9998774 PP
>> tr|I7MKV3|I7MKV3_TETTS Arginine N-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.7 0.1 7.9e-06 0.018 16 56 .. 112 152 .. 98 195 .. 0.82
Alignments for each domain:
== domain 1 score: 14.7 bits; conditional E-value: 7.9e-06
HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEE CS
RrnaAD 16 kkvineIldklnleekltvleigpGkGilTeeLakrakqvv 56
k +++Ild+ nl e + vl+ig G+Gil+ ak ++v
tr|I7MKV3|I7MKV3_TETTS 112 KAYMKSILDNKNLFEGKIVLDIGCGTGILSIFAAKAGAKHV 152
5689*************************976666655554 PP
>> tr|Q239D4|Q239D4_TETTS Cyclopropane-fatty-acyl-phospholipid synthase OS=Tetrahymena thermophila (strain SB210) OX=31
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.3 0.1 1.1e-05 0.025 32 93 .. 51 115 .. 29 195 .. 0.86
Alignments for each domain:
== domain 1 score: 14.3 bits; conditional E-value: 1.1e-05
SEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHH CS
RrnaAD 32 ltvleigpGkGilTeeLakra...kqvvvlElderLakllqkklskdeklkvvhqDflkfetpee 93
+ +l+ig G+G+ ++a + + + +de+ +k qk +++++++++ q+f++ + ++e
tr|Q239D4|Q239D4_TETTS 51 DSILDIGIGTGLPLYKIASKFpqnAKILGVDIDENYVKAAQKLFKDKKNVEIRLQNFYELDAKKE 115
78**********999999998877778889*****************************999884 PP
>> tr|Q22R62|Q22R62_TETTS Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Tetrahymena thermophila
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.9 0.2 1.4e-05 0.031 57 164 .. 91 224 .. 71 228 .. 0.79
Alignments for each domain:
== domain 1 score: 13.9 bits; conditional E-value: 1.4e-05
EE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHHCT.................TTCCCCEEEEEEE--TTTHHHHHHHHHH.. CS
RrnaAD 57 vlElderLakllqkklskdeklkvvhqDflkfetpeevte.................kdsihqeflvvanlPyeistqlvkqlle.. 124
+E+ ++L+++ +k+++++ +k+v+ Dflk + p v+ +si +++ + + + e+s +v+ + +
tr|Q22R62|Q22R62_TETTS 91 NVEKAQALVEEIKKTINDKIDVKIVQIDFLKVNQPGVVQAavkqvedvdisllvnnaGMSIANKLSIESYTEEELSNTIVFNIYSqv 177
58**********************************87779999**********999999999999999999999999999998867 PP
.........GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHH CS
RrnaAD 125 .........esrfglvkmllwlqkefarrllarpgskkrsrlsvlreaf 164
+ k ++ + + + ++ g++ + ++ ++ +f
tr|Q22R62|Q22R62_TETTS 178 fftyyllpkLRNR--GKKSGIINLSSVSTVASMAGFHIYTSTKIFNDYF 224
7777777543333..3333444555555555555777777777766665 PP
>> tr|Q22D66|Q22D66_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_009
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.3 0.0 9e-05 0.2 5 65 .. 17 80 .. 13 113 .. 0.78
2 ? -2.1 0.0 1.1 2.4e+03 209 239 .. 169 198 .. 156 204 .. 0.70
Alignments for each domain:
== domain 1 score: 11.3 bits; conditional E-value: 9e-05
XXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHH CS
RrnaAD 5 rksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakra...kqvvvlElderLa 65
++y + + + + + ++ l++++ +le+g+G G+l + +++ ++v+ l e+++
tr|Q22D66|Q22D66_TETTS 17 SQNYVNMYNGSSTFYLSLINMLQIQNRNCILEVGAGSGFLFHHTMNYKkseAKYVATDLSENML 80
4455555666788888999*********************999988874455677766666665 PP
== domain 2 score: -2.1 bits; conditional E-value: 1.1
HHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT CS
RrnaAD 209 vvrkllnrkrktlstslksllpggelqalss 239
+++ +l+ ++ l+t++ s+++ +++q+l++
tr|Q22D66|Q22D66_TETTS 169 IISDILT-EYGCLNTQIRSNFHLNNRQKLIQ 198
5555554.57788899999999888888754 PP
>> tr|Q24D56|Q24D56_TETTS UbiE/COQ5 methyltransferase, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.1 0.0 4.8e-05 0.11 23 73 .. 36 89 .. 16 119 .. 0.87
Alignments for each domain:
== domain 1 score: 12.1 bits; conditional E-value: 4.8e-05
HHHH-GGTTSEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHHCHTT CS
RrnaAD 23 ldklnleekltvleigpGkGilTeeLakra...kqvvvlElderLakllqkkls 73
l+ l+++ +++le+g+G G+l ++ +++ ++v+ l e+++ +l k+l+
tr|Q24D56|Q24D56_TETTS 36 LNMLKVNTRKQILEVGAGAGFLYNHTMNYKrpeASYVATDLSEKMLSILCKRLQ 89
6667778999****************999988889*********9999999876 PP
>> tr|I7MB26|I7MB26_TETTS Spermine/spermidine synthase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.7 0.0 0.00013 0.29 33 79 .. 200 249 .. 187 277 .. 0.81
Alignments for each domain:
== domain 1 score: 10.7 bits; conditional E-value: 0.00013
EEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHHCHTTTCCCEE CS
RrnaAD 33 tvleigpGkGilTeeLakra...kqvvvlElderLakllqkklskdeklk 79
+l ig G + + L++ + k+ +v E+der ++ ++k ++ +e+++
tr|I7MB26|I7MB26_TETTS 200 HILIIGGGDMLIANYLLESFpnvKKITVCEIDERVVENVRKYFKMSENIN 249
578899999999999*9999999******************999555543 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (265 nodes)
Target sequences: 26971 (16912921 residues searched)
Passed MSV filter: 3017 (0.111861); expected 539.4 (0.02)
Passed bias filter: 187 (0.00693337); expected 539.4 (0.02)
Passed Vit filter: 31 (0.00114938); expected 27.0 (0.001)
Passed Fwd filter: 12 (0.000444922); expected 0.3 (1e-05)
Initial search space (Z): 26971 [actual number of targets]
Domain search space (domZ): 12 [number of targets reported over threshold]
# CPU time: 0.33u 0.02s 00:00:00.35 Elapsed: 00:00:00.12
# Mc/sec: 37349.37
//
[ok]