# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/RrnaAD.hmm.txt
# target sequence database:        proteomes/Trichomonas_vaginalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       RrnaAD  [M=265]
Accession:   PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    4.2e-58  198.0   0.0    5.2e-58  197.7   0.0    1.1  1  tr|A2EVN6|A2EVN6_TRIVA  rRNA adenine N(6)-methyltransferase O
    0.00017   22.2   0.0    0.00022   21.9   0.0    1.1  1  tr|A2FEZ1|A2FEZ1_TRIVA  S-adenosylmethionine-dependent methyl
     0.0058   17.2   0.0     0.0066   17.0   0.0    1.2  1  tr|A2F2A3|A2F2A3_TRIVA  Menaquinone biosynthesis methyltransf
     0.0086   16.6   0.1      0.032   14.8   0.0    1.8  2  tr|A2FAI4|A2FAI4_TRIVA  Uncharacterized protein OS=Trichomona
  ------ inclusion threshold ------
      0.018   15.6   0.0      0.025   15.1   0.0    1.2  1  tr|A2DNX4|A2DNX4_TRIVA  Arginine methyltransferase, putative 
      0.042   14.4   0.0      0.067   13.7   0.0    1.3  1  tr|A2EXH2|A2EXH2_TRIVA  Uncharacterized protein OS=Trichomona
      0.047   14.2   0.0      0.064   13.8   0.0    1.2  1  tr|A2FCQ2|A2FCQ2_TRIVA  Arginine methyltransferase, putative 
      0.077   13.5   0.0       0.12   12.9   0.0    1.2  1  tr|A2H3A0|A2H3A0_TRIVA  Uncharacterized protein OS=Trichomona
       0.12   12.9   0.0       0.18   12.3   0.0    1.2  1  tr|A2G2M2|A2G2M2_TRIVA  Uncharacterized protein OS=Trichomona


Domain annotation for each sequence (and alignments):
>> tr|A2EVN6|A2EVN6_TRIVA  rRNA adenine N(6)-methyltransferase OS=Trichomonas vaginalis OX=5722 GN=TVAG_299080 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  197.7   0.0   9.4e-62   5.2e-58       3     254 ..      16     249 ..      14     262 .. 0.89

  Alignments for each domain:
  == domain 1  score: 197.7 bits;  conditional E-value: 9.4e-62
                             CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGH CS
                  RrnaAD   3 klrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkklskdeklkvvhqDflkf 88 
                             k+  s+gqn+l++k v+++I+d+ ++++ +++leigpG G++Tee++ r   +v ++E+d+r++ +l+kk+  +++l ++++D+l  
  tr|A2EVN6|A2EVN6_TRIVA  16 KMDHSLGQNILRSKVVVKNIVDAGEPRPGDKILEIGPGNGNMTEEMLSREgIEVIAIEKDQRMCVELKKKFPRHPNLRIINADVLSV 102
                             67789********************************************99************************************ PP

                             HHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-G CS
                  RrnaAD  89 etpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakvek 175
                             ++pe+           l+++n+Py+is+++v++ll  ++f  ++ +l++qkef +r++arpg+  ++rl ++++++++vklv++v +
  tr|A2EVN6|A2EVN6_TRIVA 103 DLPEFD----------LCISNIPYNISSAIVFKLLARPTF--RRTVLMVQKEFGERIVARPGKDGWGRLAINTQLYASVKLVMNVSR 177
                             ****77..........9******************98888..9******************************************** PP

                             GCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T--TTTCCCCSGHH CS
                  RrnaAD 176 sifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalsstgindnalvkklsae 254
                             ++f Pppkvds +v +++++ + p+ d ++++ +++ +++r ++tl++ +++    ++ +al ++  n ++ +  ++ +
  tr|A2EVN6|A2EVN6_TRIVA 178 KNFVPPPKVDSIVVSIQPREVQ-PDIDFNEWDGLIKLCFTRPNRTLQATFHK----KKIRALLNE--NREKYLSSINQQ 249
                             *********************9.8***********************98653....333333332..333333333333 PP

>> tr|A2FEZ1|A2FEZ1_TRIVA  S-adenosylmethionine-dependent methyltransferase, putative OS=Trichomonas vaginalis OX=5722 G
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   0.0   3.9e-08   0.00022      19      93 ..      29     105 ..      22     133 .. 0.88

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 3.9e-08
                             HHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT..TCCCEEEE-S-CCGHHHHHH CS
                  RrnaAD  19 ineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls..kdeklkvvhqDflkfetpee 93 
                             ++e+ +++n++++  +l+ g G+G+    L + ak    l   + +++ ++k+l   +++++++++q++ ++ +  +
  tr|A2FEZ1|A2FEZ1_TRIVA  29 VAEVRKQANITPESRILDFGCGTGLNGIYLINDAKTIGFLDPSSGMIEQVKKELAeiNKTNVEIYNQEISQTTMEPF 105
                             667889**********************************************999999***********99877664 PP

>> tr|A2F2A3|A2F2A3_TRIVA  Menaquinone biosynthesis methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   1.2e-06    0.0066      32      96 ..      60     125 ..      46     190 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 1.2e-06
                             SEEEEES-TTTCCHHHH.HCC-SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHHHHHHHCT CS
                  RrnaAD  32 ltvleigpGkGilTeeL.akrakqvvvlElderLakllqkklskdeklkvvhqDflkfetpeevte 96 
                              t l +g G  ++T eL ++ +++vv +   e+ +  ++kk ++++kl++   D+ k+++p++  +
  tr|A2F2A3|A2F2A3_TRIVA  60 GTALNLGCGNSNMTSELlLNGFDKVVGIDFSEVVIGQMRKKYQLEQKLEWETGDITKMKFPNNHFD 125
                             57799**********99899******************************************7655 PP

>> tr|A2FAI4|A2FAI4_TRIVA  Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_415010 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   5.7e-06     0.032      19      83 ..      25      91 ..      14     112 .. 0.88
   2 ?   -0.4   0.0      0.24   1.4e+03     160     196 ..     109     143 ..      98     167 .. 0.61

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 5.7e-06
                            HHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT..TCCCEEEE-S CS
                  RrnaAD 19 ineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls..kdeklkvvhq 83
                            ++ I +++nl++++tvl+ g  kG+l  +L + ak+   l  d++ + + ++ l+   +++ +++++
  tr|A2FAI4|A2FAI4_TRIVA 25 VDIIKSQSNLNKSMTVLDFGCEKGFLGLKLIDDAKKIAFLDPDPNAISIAEESLKmmGKTNYEIINK 91
                            5667889*************************************99999999888888888888876 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.24
                             HHHHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS CS
                  RrnaAD 160 lreaftdvklvakveksifsPppkvdsalvelerkde 196
                              ++++ dvk  ++  ks+  P+   +++++e+  k++
  tr|A2FAI4|A2FAI4_TRIVA 109 SLHYVPDVKSALTKIKSLLNPD--GKLVIIEIYHKHF 143
                             4444445544444444444444..5556666655555 PP

>> tr|A2DNX4|A2DNX4_TRIVA  Arginine methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_225950 PE=3 SV=
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.1   0.0   4.4e-06     0.025       7      93 ..      20     113 ..      14     142 .. 0.75

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 4.4e-06
                             GCG--EE--HHHHHHHHHHH-GG....TTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT....TCCCEEEE-S- CS
                  RrnaAD   7 sygqnflknkkvineIldklnle....ekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls....kdeklkvvhqD 84 
                             s+   +l+++ v  +  +++  +    +++ vleig+G+Gi++   ak   k+v + E  ++L+++++kk      ++ k++++ q+
  tr|A2DNX4|A2DNX4_TRIVA  20 SFHDIILRDTAVFSQFEKAIRYNstlfKDKIVLEIGSGTGIFSMMAAKSGaKHVYAWE--PSLLNIYSKKTIednnLQDKITILSQN 104
                             5555566666666655554444445559999***************999857777776..899999998876577788889999998 PP

                             CCGHHHHHH CS
                  RrnaAD  85 flkfetpee 93 
                               + ++ e+
  tr|A2DNX4|A2DNX4_TRIVA 105 LEEIKLEEK 113
                             877776665 PP

>> tr|A2EXH2|A2EXH2_TRIVA  Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_253130 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   1.2e-05     0.067      32      89 ..      77     135 ..      56     163 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.2e-05
                             SEEEEES-TTTCCHHHH.HCC-SEEEEE-S-HHHHHHHHCHTTTCCCEEEE-S-CCGHH CS
                  RrnaAD  32 ltvleigpGkGilTeeL.akrakqvvvlElderLakllqkklskdeklkvvhqDflkfe 89 
                             ++  +ig+G G  +e +  k++k+  ++E  ++++ + ++kl+++  lk + + + +++
  tr|A2EXH2|A2EXH2_TRIVA  77 QKCADIGAGIGRVSELIlSKYFKEIDLVEPVQKFVDVAKEKLKNKVILKTYTCGAQDWK 135
                             6778**********96659***********************98888888888887776 PP

>> tr|A2FCQ2|A2FCQ2_TRIVA  Arginine methyltransferase, putative OS=Trichomonas vaginalis OX=5722 GN=TVAG_048280 PE=3 SV=
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   1.1e-05     0.064       7      93 ..      20     113 ..      14     141 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.1e-05
                             GCG--EE--HHHHHHHHHHH-GG....TTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT....TCCCEEEE-S-C CS
                  RrnaAD   7 sygqnflknkkvineIldklnle....ekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls....kdeklkvvhqDf 85 
                             s+   +l+++ v  +  +++  +    +++ vleig+G+Gi++   ak   ++v     ++L+++++kk      ++ k++++ q+ 
  tr|A2FCQ2|A2FCQ2_TRIVA  20 SFHDIILRDTAVFSQFEKAIRYNstlfKDKIVLEIGSGTGIFSMMAAKSGAKHVYA-WKPSLLNIYSKKTIednnLQDKITILSQNL 105
                             5555566666666655554444445559999*****************99888755.567888888777655777888899999988 PP

                             CGHHHHHH CS
                  RrnaAD  86 lkfetpee 93 
                              + ++ e+
  tr|A2FCQ2|A2FCQ2_TRIVA 106 EEIKLEEK 113
                             77766665 PP

>> tr|A2H3A0|A2H3A0_TRIVA  Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_207000 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   2.2e-05      0.12      55     126 ..     108     186 ..     103     203 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.2e-05
                             EEEE-S-HHHHHHHHCHTTTCCCEEE.E-S-CCGHHHHHHHCT........TTCCCCEEEEEEE--TTTHHHHHHHHHHGG CS
                  RrnaAD  55 vvvlElderLakllqkklskdeklkv.vhqDflkfetpeevte........kdsihqeflvvanlPyeistqlvkqllees 126
                             ++ +E++ +L+ +++   +k++ +k+  ++ ++k  +    +         k  +++  +vv ++P ++++q+++ +++++
  tr|A2H3A0|A2H3A0_TRIVA 108 LTNIESRIALVDFYNL--KKANSIKIlFNKQIYKDRILDVTYAplkkildpKNPPNNGTIVVFHIPEQVTEQMIFSIFSKY 186
                             789***********99..89999**9889999999999977779999******************************9955 PP

>> tr|A2G2M2|A2G2M2_TRIVA  Uncharacterized protein OS=Trichomonas vaginalis OX=5722 GN=TVAG_467070 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   3.3e-05      0.18      55     126 ..     170     248 ..     165     265 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.3e-05
                             EEEE-S-HHHHHHHHCHTTTCCCEEE.E-S-CCGHHHHHHHCT........TTCCCCEEEEEEE--TTTHHHHHHHHHHGG CS
                  RrnaAD  55 vvvlElderLakllqkklskdeklkv.vhqDflkfetpeevte........kdsihqeflvvanlPyeistqlvkqllees 126
                             ++ +E++ +L+ +++   +k++ +k+  ++ ++k  +    +         k  +++  +vv ++P ++++q+++ +++++
  tr|A2G2M2|A2G2M2_TRIVA 170 LTNIESRIALVDFYNL--KKANSIKIlFNKQIYKDRILDVTYAplkkildpKNPPNNGTIVVFHIPEQVTEQMIFSIFSKY 248
                             789***********99..89999**9889999999999977779999******************************9955 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (265 nodes)
Target sequences:                        50190  (17055200 residues searched)
Passed MSV filter:                      1918  (0.0382148); expected 1003.8 (0.02)
Passed bias filter:                      719  (0.0143256); expected 1003.8 (0.02)
Passed Vit filter:                        48  (0.000956366); expected 50.2 (0.001)
Passed Fwd filter:                         9  (0.000179319); expected 0.5 (1e-05)
Initial search space (Z):              50190  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.34u 0.01s 00:00:00.35 Elapsed: 00:00:00.13
# Mc/sec: 34766.37
//
[ok]