# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/RrnaAD.hmm.txt # target sequence database: proteomes/Trichoplax_adhaerens.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: RrnaAD [M=265] Accession: PF00398.19 Description: Ribosomal RNA adenine dimethylase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-64 217.2 0.1 1.6e-64 216.9 0.1 1.0 1 tr|B3S4V8|B3S4V8_TRIAD rRNA adenine N(6)-methyltransferase O 3.8e-38 130.5 0.0 4.5e-38 130.2 0.0 1.1 1 tr|B3RWS2|B3RWS2_TRIAD rRNA adenine N(6)-methyltransferase O 3.6e-18 65.0 0.0 4.8e-18 64.5 0.0 1.1 1 tr|B3S0S8|B3S0S8_TRIAD rRNA adenine N(6)-methyltransferase O 9.8e-08 30.7 0.0 1.4e-07 30.3 0.0 1.3 1 tr|B3SA59|B3SA59_TRIAD Uncharacterized protein OS=Trichoplax 0.0048 15.4 0.0 0.007 14.8 0.0 1.2 1 tr|B3RJQ6|B3RJQ6_TRIAD Protein-L-isoaspartate O-methyltransf ------ inclusion threshold ------ 0.01 14.3 0.0 0.016 13.7 0.0 1.2 1 tr|B3S8A4|B3S8A4_TRIAD Uncharacterized protein OS=Trichoplax 0.042 12.3 0.0 0.042 12.3 0.0 1.1 1 tr|B3SF37|B3SF37_TRIAD Uncharacterized protein (Fragment) OS 0.043 12.3 0.0 0.078 11.4 0.0 1.4 1 tr|B3RVI8|B3RVI8_TRIAD Uncharacterized protein OS=Trichoplax 0.075 11.5 0.0 0.12 10.8 0.0 1.3 1 tr|B3S2L1|B3S2L1_TRIAD Uncharacterized protein (Fragment) OS Domain annotation for each sequence (and alignments): >> tr|B3S4V8|B3S4V8_TRIAD rRNA adenine N(6)-methyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_29342 PE=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 216.9 0.1 1.3e-67 1.6e-64 9 252 .. 2 232 .. 1 246 [. 0.92 Alignments for each domain: == domain 1 score: 216.9 bits; conditional E-value: 1.3e-67 G--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHH CS RrnaAD 9 gqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpe 92 gq++lkn+ ++n+I++k+ ++ ++tvleigpG+G+lT++L++ ak+v + E d+rLa++lqk+++ ++kl ++ D+lk+e+p+ tr|B3S4V8|B3S4V8_TRIAD 2 GQHILKNPLIVNSIVEKAAIRSTDTVLEIGPGTGNLTVKLLQKAKKVIACEVDPRLAAELQKRVQgspVSTKLHIIVGDVLKTELPY 88 9****************************************************************9999****************** PP HHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCEC CS RrnaAD 93 evtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveksifs 179 + +vanlPy+is+++v++ll ++r+ ++ ++l++q+efa rl+a+pg+k+++rls+++++++ v ++ kv+k++f+ tr|B3S4V8|B3S4V8_TRIAD 89 FD----------VCVANLPYQISSPFVFKLL-LHRPLFRCAVLMFQREFALRLVAKPGDKLYCRLSINTQLLAKVDHLIKVGKNNFR 164 77..........7******************.899999************************************************* PP S--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHHCTT.T--TTTCCCCSG CS RrnaAD 180 Pppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqalsstgindnalvkkls 252 Pppkv+s++v++e++++ p + k+++ ++r++++rk++tls+s+k+ + + l+++ + + + + tr|B3S4V8|B3S4V8_TRIAD 165 PPPKVESSVVRIEPINPV-PPINFKEWDGLTRIVFARKNRTLSASFKTQGVQTMLEKN----FRIHCSIHNQA 232 *****************6.89************************9977766666554....33444444444 PP >> tr|B3RWS2|B3RWS2_TRIAD rRNA adenine N(6)-methyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_24833 PE=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 130.2 0.0 3.5e-41 4.5e-38 3 236 .. 20 267 .. 18 298 .. 0.89 Alignments for each domain: == domain 1 score: 130.2 bits; conditional E-value: 3.5e-41 CCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHH.HCC-SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCG CS RrnaAD 3 klrksygqnflknkkvineIldklnleekltvleigpGkGilTeeL.akrakqvvvlElderLakllqkkls.kdeklkvvhqDflk 87 ++ k+++qnfl n ++ n+I+ e+ +v e+g+G+G lT+++ a a + v++E+d+r++ l + d+++ +v +D+l+ tr|B3RWS2|B3RWS2_TRIAD 20 SASKQLSQNFLLNSNITNKIVLLDGGVENHQVCEVGAGPGCLTRSIiAGGASKIVAVEKDRRFLPALDILANaVDGRMVIVYADILN 106 56789****************888888******************978888*****************987799************* PP HHHHHHHCT......TTCCCCEEEEEEE--TTTHHHHHHHHHH........GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHH CS RrnaAD 88 fetpeevte......kdsihqeflvvanlPyeistqlvkqlle........esrfglvkmllwlqkefarrllarpgskkrsrlsvl 160 +e+ + + ++++++nlP ist+l q+l+ g+ km+l +q+e+a+r+la+p ++rsrls++ tr|B3RWS2|B3RWS2_TRIAD 107 YEMIKAF-DpvdkkaWNDESPKMKIIGNLPFSISTPLLIQWLNlisqnagpF-SLGRIKMTLTFQEEVAQRILAEPKTSQRSRLSIM 191 ****955.45888765566789***********************9998852.34467***************************** PP HHHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHHH CS RrnaAD 161 reaftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelqa 236 ++ ++ vk+ + s+f P pkv+s+++ +++ ++l + d +e + + l+ +rk + + k+l+p + + tr|B3RWS2|B3RWS2_TRIAD 192 TQNYCHVKPGFLIKGSSFVPAPKVNSVVLTFTPRITPLIDIDFTTLEVIAKSLFRHRRKFVIKGTKYLFPTDVDLS 267 ************************************99999****************************9887444 PP >> tr|B3S0S8|B3S0S8_TRIAD rRNA adenine N(6)-methyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_57156 PE=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 64.5 0.0 3.8e-21 4.8e-18 5 261 .. 27 314 .. 24 318 .. 0.87 Alignments for each domain: == domain 1 score: 64.5 bits; conditional E-value: 3.8e-21 XXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT..TCCCEEEE-S-CCGH CS RrnaAD 5 rksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls..kdeklkvvhqDflkf 88 + + + l+n+++++++ + k ++e pG+G+lT+ L++ q+v+lE+ ++++ +l++ l+ +d++lk + D+ k tr|B3S0S8|B3S0S8_TRIAD 27 NIKASHRHLINPQTADKVAKSFGDLHKYVIIEKDPGPGVLTKALLNAGcTQLVALESNQKFLSVLKE-LEndSDGRLKAYYSDINKL 112 66778889**************999*******************66544******************.5559*************** PP HHHHHHCT.....................TTCCCCEEEEEEE--T..TTHHHHHHHHHH...GGGGCEEEEEEEEEHHHHHHHH--T CS RrnaAD 89 etpeevte.....................kdsihqeflvvanlPy..eistqlvkqlle...esrfglvkmllwlqkefarrllarp 149 ++ + + d i + + van + + +l+e ++r g+ + + +++ar l a tr|B3S0S8|B3S0S8_TRIAD 113 DLIPLY-QgyippvyqsgdilghikpkswDDDIVGRVIGVANNTMghRFTISYLIRLIErsgLHRWGRWQHIAYYTEKTARALYAHV 198 ****55.55*****************9887777777777777554235666666677779*************************** PP TSTT-SHHHHHHHHHEEEEEEEEC-GGCECS--...SSSE.EEEEEEE-SS-S.--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTC CS RrnaAD 150 gskkrsrlsvlreaftdvklvakveksifsPpp...kvds.alvelerkdedl.pqkdlkkyesvvrkllnrkrktlstslksllpg 231 g ++r++vl+++++++ ++ k f P k +s l+ le k++ ++++lk ++ +++++++ +r++l + l+s+ pg tr|B3S0S8|B3S0S8_TRIAD 199 GTPIYGRITVLSNILCNISTLSKDHIDEFFPRGmaiKGNSmELICLETKKHCElSDEALKFLDPILQQVFAARRQPLLNRLESIAPG 285 *************************999999842224455889****9999878********************************9 PP HHHHHCTT.T--TTTCCCCSGHHHHHHHHH CS RrnaAD 232 gelqalsstgindnalvkklsaeqtldifk 261 + + l + +i + + + s+ +++++++ tr|B3S0S8|B3S0S8_TRIAD 286 SY-TVLEKLKIPPRKCASNMSPMDFVELAE 314 98.444343899999999999888888776 PP >> tr|B3SA59|B3SA59_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_61143 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.3 0.0 1.1e-10 1.4e-07 16 97 .. 55 147 .. 43 196 .. 0.85 Alignments for each domain: == domain 1 score: 30.3 bits; conditional E-value: 1.1e-10 HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHHCT.. CS RrnaAD 16 kkvineIldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeevte.. 96 +k +++ ++kl+++++ +vl+ g+G G ++La + v ++E+ e+L k+ + + ++ ++ v qD++k +t +++ + tr|B3SA59|B3SA59_TRIAD 55 TKAVDDCIEKLQINKTFQVLDFGSGIGGPARHLASKSrCRVKAVEIQEDLNKIAADLTNrcgLSDRIDHVRQDIYKLDTDSNYFDca 141 678999***************************98886789999999999998888655788******************9987655 PP .....T CS RrnaAD 97 .....k 97 tr|B3SA59|B3SA59_TRIAD 142 vswlaV 147 555552 PP >> tr|B3RJQ6|B3RJQ6_TRIAD Protein-L-isoaspartate O-methyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_495 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.8 0.0 5.5e-06 0.007 25 74 .. 73 132 .. 66 145 .. 0.80 Alignments for each domain: == domain 1 score: 14.8 bits; conditional E-value: 5.5e-06 HH-GGTTSEEEEES-TTTCCHHHHHCC-...SEEEEE-S-HHHHHHHHCHTT.......T CS RrnaAD 25 klnleekltvleigpGkGilTeeLakra...kqvvvlElderLakllqkkls.......k 74 ++nl+e t+l++g+G G lT+ +a ++ +v +E ++L+ l +++++ + tr|B3RJQ6|B3RJQ6_TRIAD 73 ASNLKEGCTILDVGSGSGYLTACMAMMVgssGKVYGIEHIPELISLSRNNINkfnpsllE 132 68**********************999988888999999999999998877644444444 PP >> tr|B3S8A4|B3S8A4_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_60467 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 1.2e-05 0.016 22 94 .. 19 94 .. 10 114 .. 0.81 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 1.2e-05 HHHHH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHH CS RrnaAD 22 IldklnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeev 94 Il+++n ++ vl++g+G+Gil+ ++ ++v ++E +++a+ +k + k+ v++ + + e+pe+v tr|B3S8A4|B3S8A4_TRIAD 19 ILKNANRIRNKVVLDVGAGTGILSHFCVEAGaRKVYAVEA-SAIAEQAKKVALannAQDKISVINDLVENIELPEKV 94 88889988999**************9999877*******7.567777777443666778888888777777777755 PP >> tr|B3SF37|B3SF37_TRIAD Uncharacterized protein (Fragment) OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_9885 PE=4 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 3.3e-05 0.042 35 58 .. 33 56 .. 10 86 .. 0.79 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 3.3e-05 EEES-TTTCCHHHHHCC-SEEEEE CS RrnaAD 35 leigpGkGilTeeLakrakqvvvl 58 ++++ G+G+ T++L k++kqv l tr|B3SF37|B3SF37_TRIAD 33 VDVACGPGLCTQPLGKYFKQVIGL 56 79******************9654 PP >> tr|B3RVI8|B3RVI8_TRIAD Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_55668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 6.1e-05 0.078 33 70 .. 124 161 .. 122 202 .. 0.88 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 6.1e-05 EEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHC CS RrnaAD 33 tvleigpGkGilTeeLakrakqvvvlElderLakllqk 70 t+l++g+G G+ T +a+ +++v+v E +++ +l+ tr|B3RVI8|B3RVI8_TRIAD 124 TMLDLGAGDGNITSVMAEFVEKVSVTEVSKSMRWRLNR 161 79*************************99998777765 PP >> tr|B3S2L1|B3S2L1_TRIAD Uncharacterized protein (Fragment) OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_1535 PE=3 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 9.3e-05 0.12 16 92 .. 35 115 .. 23 142 .. 0.72 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 9.3e-05 HHHHHHHHHHH-GG.TTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHH..HHHHHCHTTTCCCEEEE-S-CCGHHHHH CS RrnaAD 16 kkvineIldklnle.ekltvleigpGkGilTeeLakra.kqvvvlElderL..akllqkklskdeklkvvhqDflkfetpe 92 ++++++++ + + +++ vl++g+G Gil+ ++ ++v ++E + a+ l + ++++k+++v+ + + e+pe tr|B3S2L1|B3S2L1_TRIAD 35 TSTYQRAILQNSIDfQNKVVLDVGAGSGILSFFAVQAGaRKVYAVEASSIAihAENLIHSNQLSPKIQIVKGRIEEIEIPE 115 4567777777777789999***********975544435999999986543113333343337888888887776666665 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 11518 (5222075 residues searched) Passed MSV filter: 416 (0.0361174); expected 230.4 (0.02) Passed bias filter: 212 (0.018406); expected 230.4 (0.02) Passed Vit filter: 27 (0.00234416); expected 11.5 (0.001) Passed Fwd filter: 9 (0.000781386); expected 0.1 (1e-05) Initial search space (Z): 11518 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.10u 0.01s 00:00:00.11 Elapsed: 00:00:00.04 # Mc/sec: 34596.25 // [ok]