# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/RrnaAD.hmm.txt
# target sequence database: proteomes/Trypanosoma_brucei.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: RrnaAD [M=265]
Accession: PF00398.19
Description: Ribosomal RNA adenine dimethylase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
7.9e-63 210.9 0.0 9.8e-63 210.6 0.0 1.2 1 tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase O
9.5e-25 86.1 0.0 1.1e-14 53.1 0.0 2.1 2 tr|Q38BN0|Q38BN0_TRYB2 rRNA adenine N(6)-methyltransferase O
4.6e-06 24.8 0.1 7.4e-06 24.2 0.1 1.2 1 sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase
0.00037 18.6 0.0 0.00065 17.8 0.0 1.3 1 tr|Q57WE9|Q57WE9_TRYB2 Protein arginine methyltransferase ND
0.0025 15.9 0.0 0.0035 15.4 0.0 1.1 1 tr|Q38AH9|Q38AH9_TRYB2 Protein-L-isoaspartate, putative OS=T
------ inclusion threshold ------
0.015 13.3 0.0 0.02 12.9 0.0 1.1 1 tr|Q57YY7|Q57YY7_TRYB2 Uncharacterized protein OS=Trypanosom
Domain annotation for each sequence (and alignments):
>> tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 210.6 0.0 6.9e-66 9.8e-63 4 227 .. 62 275 .. 59 321 .. 0.95
Alignments for each domain:
== domain 1 score: 210.6 bits; conditional E-value: 6.9e-66
CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS
RrnaAD 4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87
++k +gq++lkn+ vi+ I++k+ +++++ vleigpG+G+lTe+L++ ak+v ++E d+r++++l+k+++ +++kl+v+ + l+
tr|Q585P9|Q585P9_TRYB2 62 FNKGFGQHILKNPLVIAAIVEKAAVKPTDIVLEIGPGTGNLTEKLLQAAKKVIAFEVDPRMVAELNKRFQnspLAPKLQVIRGNCLD 148
7899******************************************************************9999************* PP
HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC- CS
RrnaAD 88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakve 174
e+p++ ++van+Py is++lv++ll+ + f + ++l++q+efa r +a+pgs +++rlsv++++++ +++k+
tr|Q585P9|Q585P9_TRYB2 149 HEFPYFD----------KCVANVPYAISSALVFKLLKRPNF--KCAVLMFQREFALRVCAQPGSEAYCRLSVNSQLLARCSHLMKIS 223
*****77..........8******************86666..******************************************** PP
GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCC CS
RrnaAD 175 ksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslks 227
k++f Pppkv+s++++l++k++ p +d ++++ +v++++nrk+k++s + +
tr|Q585P9|Q585P9_TRYB2 224 KNSFNPPPKVESSVIRLDPKHPA-PSVDFEEWDGLVKHIFNRKNKKVSSIFRT 275
**********************8.8**********************988764 PP
>> tr|Q38BN0|Q38BN0_TRYB2 rRNA adenine N(6)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 30.9 0.0 4.5e-11 6.4e-08 7 92 .. 67 158 .. 65 178 .. 0.84
2 ! 53.1 0.0 7.9e-18 1.1e-14 102 260 .. 279 448 .. 260 452 .. 0.92
Alignments for each domain:
== domain 1 score: 30.9 bits; conditional E-value: 4.5e-11
GCG--EE--HHHHHHHHHHH-GG....TTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCG CS
RrnaAD 7 sygqnflknkkvineIldklnle....ekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls.kdeklkvvhqDflk 87
+ygq f+ n k+ ++ l + +++ +le+gpG G+lT++L+ r v +E+der+ +l++ + ++k ++ + D+l
tr|Q38BN0|Q38BN0_TRYB2 67 KYGQRFILNLKLTHQVAALLSRTtlrtPDKLLLELGPGAGALTRSLLTRPcVGVLGIEQDERFNGHLEQIRQyTNGKFQWTNGDVLR 153
8***********9998766555555599999***************8886699**************99555899**********99 PP
HHHHH CS
RrnaAD 88 fetpe 92
+ e
tr|Q38BN0|Q38BN0_TRYB2 154 INELE 158
87666 PP
== domain 2 score: 53.1 bits; conditional E-value: 7.9e-18
CEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCECS- CS
RrnaAD 102 qeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveksifsPp 181
++ v+anlP +i t+l +++ + fg+v ++ +q+e+a+ ++a+ gs srlsvl + f+ ++l+ + + + P+
tr|Q38BN0|Q38BN0_TRYB2 279 AKLEVIANLPFNIITELLMRYAVdcsrkqnLFVFGRVPLHVFTQQEVAECIIAPAGSIHFSRLSVLCQCFFHTQLLRTFREMTYYPK 365
6899*******98888888887679999988999***************************************************** PP
-SSSEEEEEEEE-SS-S.--S-HHHHHHHHHHHHC..TTTSBCCCHCCCTSTCHHHHHCTT..T--TTTCCCCSGHHHHHHHH CS
RrnaAD 182 pkvdsalvelerkdedl.pqkdlkkyesvvrklln..rkrktlstslksllpggelqalsst.gindnalvkklsaeqtldif 260
v +al+ l++++ +l p +d + + ++ l+ ++ t+ ++l++ +p + +q++ ++ + + +v +l+ e++++++
tr|Q38BN0|Q38BN0_TRYB2 366 TAVLGALITLQPRAVPLlPGLDAATLIHFTDLLMRpgQRGMTVYKALQQHVPPEVAQYMLQElRTDGALTVLDLTTEEVCKLA 448
**********************************7558999*******************99888888888888888888765 PP
>> sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase 7 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 24.2 0.1 5.2e-09 7.4e-06 25 82 .. 90 151 .. 81 161 .. 0.89
Alignments for each domain:
== domain 1 score: 24.2 bits; conditional E-value: 5.2e-09
HH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE- CS
RrnaAD 25 klnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls...kdeklkvvh 82
k +++++ vleig+G G+l+ ak k vv++E e+Lakl +++++ ++++kv+h
sp|Q582G4|ANM7_TRYB2 90 KKHVTPETGVLEIGAGSGLLSLMAAKLGaKWVVAVEGSEELAKLARENIRannMEHQVKVLH 151
446899********************988******************999888889999987 PP
>> tr|Q57WE9|Q57WE9_TRYB2 Protein arginine methyltransferase NDUFAF7 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.8 0.0 4.5e-07 0.00065 25 89 .. 173 248 .. 162 275 .. 0.86
Alignments for each domain:
== domain 1 score: 17.8 bits; conditional E-value: 4.5e-07
HH-GGTTSEEEEES-TTTCCHHHHHCC-..........SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHH CS
RrnaAD 25 klnleekltvleigpGkGilTeeLakra..........kqvvvlElderLakllqkkls.kdeklkvvhqDflkfe 89
k ++++ l v++ig+G G+l +++++++ ++ v+E+ ++L+++l+++l ++ +k+ + +l++
tr|Q57WE9|Q57WE9_TRYB2 173 KFDPRDPLVVYDIGAGSGALAVSVLDYLsehfpsvyeqCEYHVVEINPQLVQVLRNRLImHYHHVKIHNISILNWR 248
677888999******************9755555554335689*************9998999****999999996 PP
>> tr|Q38AH9|Q38AH9_TRYB2 Protein-L-isoaspartate, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.4 0.0 2.4e-06 0.0035 30 86 .. 88 155 .. 69 160 .. 0.74
Alignments for each domain:
== domain 1 score: 15.4 bits; conditional E-value: 2.4e-06
TTSEEEEES-TTTCCHHHHHCC-....SEEEEE-S-HHHHHHHHCHTT.......TCCCEEEE-S-CC CS
RrnaAD 30 ekltvleigpGkGilTeeLakra....kqvvvlElderLakllqkkls.......kdeklkvvhqDfl 86
+ tvl++g+G G lT+ La+ + v +E ++L+ + ++ ++ +++++k ++ D+
tr|Q38AH9|Q38AH9_TRYB2 88 KPATVLDVGSGSGYLTAVLAELCsgrgGTVIGVEHISELVVRSTEVVNkhfrswvEEGRIKFIEGDGR 155
6689*******************995556667899999997766655544447777778888887765 PP
>> tr|Q57YY7|Q57YY7_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.9 0.0 1.4e-05 0.02 149 254 .. 57 158 .. 53 163 .. 0.82
Alignments for each domain:
== domain 1 score: 12.9 bits; conditional E-value: 1.4e-05
TTSTT-SHHHHHHHHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHH CS
RrnaAD 149 pgskkrsrlsvlreaftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelq 235
++k+rs sv +ea ++ ++ +v+k f p s +v+ler++ d ++d+ +y ++++ + + ++++ l+ +++++ +
tr|Q57YY7|Q57YY7_TRYB2 57 GNDKRRSLKSVEVEA-NSLSPLCEVDKFQFERLPLTVSEIVRLERRTRD-YVLDVTRYPRILYTVEEETPTEVKGTLELRGERKAIT 141
466777777777776.478999***************************.5*************************99444444433 PP
HCTT..T--TTTCCCCSGHH CS
RrnaAD 236 alsst.gindnalvkklsae 254
t ++ + l++ ++++
tr|Q57YY7|Q57YY7_TRYB2 142 C---TkSVEGPELIVRCPID 158
3...3379999999888875 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (265 nodes)
Target sequences: 8561 (4332363 residues searched)
Passed MSV filter: 196 (0.0228945); expected 171.2 (0.02)
Passed bias filter: 157 (0.018339); expected 171.2 (0.02)
Passed Vit filter: 29 (0.00338745); expected 8.6 (0.001)
Passed Fwd filter: 6 (0.000700853); expected 0.1 (1e-05)
Initial search space (Z): 8561 [actual number of targets]
Domain search space (domZ): 6 [number of targets reported over threshold]
# CPU time: 0.09u 0.00s 00:00:00.09 Elapsed: 00:00:00.04
# Mc/sec: 28701.90
//
[ok]