# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/RrnaAD.hmm.txt # target sequence database: proteomes/Trypanosoma_brucei.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: RrnaAD [M=265] Accession: PF00398.19 Description: Ribosomal RNA adenine dimethylase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.9e-63 210.9 0.0 9.8e-63 210.6 0.0 1.2 1 tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase O 9.5e-25 86.1 0.0 1.1e-14 53.1 0.0 2.1 2 tr|Q38BN0|Q38BN0_TRYB2 rRNA adenine N(6)-methyltransferase O 4.6e-06 24.8 0.1 7.4e-06 24.2 0.1 1.2 1 sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase 0.00037 18.6 0.0 0.00065 17.8 0.0 1.3 1 tr|Q57WE9|Q57WE9_TRYB2 Protein arginine methyltransferase ND 0.0025 15.9 0.0 0.0035 15.4 0.0 1.1 1 tr|Q38AH9|Q38AH9_TRYB2 Protein-L-isoaspartate, putative OS=T ------ inclusion threshold ------ 0.015 13.3 0.0 0.02 12.9 0.0 1.1 1 tr|Q57YY7|Q57YY7_TRYB2 Uncharacterized protein OS=Trypanosom Domain annotation for each sequence (and alignments): >> tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 210.6 0.0 6.9e-66 9.8e-63 4 227 .. 62 275 .. 59 321 .. 0.95 Alignments for each domain: == domain 1 score: 210.6 bits; conditional E-value: 6.9e-66 CXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCG CS RrnaAD 4 lrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflk 87 ++k +gq++lkn+ vi+ I++k+ +++++ vleigpG+G+lTe+L++ ak+v ++E d+r++++l+k+++ +++kl+v+ + l+ tr|Q585P9|Q585P9_TRYB2 62 FNKGFGQHILKNPLVIAAIVEKAAVKPTDIVLEIGPGTGNLTEKLLQAAKKVIAFEVDPRMVAELNKRFQnspLAPKLQVIRGNCLD 148 7899******************************************************************9999************* PP HHHHHHHCTTTCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC- CS RrnaAD 88 fetpeevtekdsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakve 174 e+p++ ++van+Py is++lv++ll+ + f + ++l++q+efa r +a+pgs +++rlsv++++++ +++k+ tr|Q585P9|Q585P9_TRYB2 149 HEFPYFD----------KCVANVPYAISSALVFKLLKRPNF--KCAVLMFQREFALRVCAQPGSEAYCRLSVNSQLLARCSHLMKIS 223 *****77..........8******************86666..******************************************** PP GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCC CS RrnaAD 175 ksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslks 227 k++f Pppkv+s++++l++k++ p +d ++++ +v++++nrk+k++s + + tr|Q585P9|Q585P9_TRYB2 224 KNSFNPPPKVESSVIRLDPKHPA-PSVDFEEWDGLVKHIFNRKNKKVSSIFRT 275 **********************8.8**********************988764 PP >> tr|Q38BN0|Q38BN0_TRYB2 rRNA adenine N(6)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.9 0.0 4.5e-11 6.4e-08 7 92 .. 67 158 .. 65 178 .. 0.84 2 ! 53.1 0.0 7.9e-18 1.1e-14 102 260 .. 279 448 .. 260 452 .. 0.92 Alignments for each domain: == domain 1 score: 30.9 bits; conditional E-value: 4.5e-11 GCG--EE--HHHHHHHHHHH-GG....TTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCG CS RrnaAD 7 sygqnflknkkvineIldklnle....ekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls.kdeklkvvhqDflk 87 +ygq f+ n k+ ++ l + +++ +le+gpG G+lT++L+ r v +E+der+ +l++ + ++k ++ + D+l tr|Q38BN0|Q38BN0_TRYB2 67 KYGQRFILNLKLTHQVAALLSRTtlrtPDKLLLELGPGAGALTRSLLTRPcVGVLGIEQDERFNGHLEQIRQyTNGKFQWTNGDVLR 153 8***********9998766555555599999***************8886699**************99555899**********99 PP HHHHH CS RrnaAD 88 fetpe 92 + e tr|Q38BN0|Q38BN0_TRYB2 154 INELE 158 87666 PP == domain 2 score: 53.1 bits; conditional E-value: 7.9e-18 CEEEEEEE--TTTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCECS- CS RrnaAD 102 qeflvvanlPyeistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveksifsPp 181 ++ v+anlP +i t+l +++ + fg+v ++ +q+e+a+ ++a+ gs srlsvl + f+ ++l+ + + + P+ tr|Q38BN0|Q38BN0_TRYB2 279 AKLEVIANLPFNIITELLMRYAVdcsrkqnLFVFGRVPLHVFTQQEVAECIIAPAGSIHFSRLSVLCQCFFHTQLLRTFREMTYYPK 365 6899*******98888888887679999988999***************************************************** PP -SSSEEEEEEEE-SS-S.--S-HHHHHHHHHHHHC..TTTSBCCCHCCCTSTCHHHHHCTT..T--TTTCCCCSGHHHHHHHH CS RrnaAD 182 pkvdsalvelerkdedl.pqkdlkkyesvvrklln..rkrktlstslksllpggelqalsst.gindnalvkklsaeqtldif 260 v +al+ l++++ +l p +d + + ++ l+ ++ t+ ++l++ +p + +q++ ++ + + +v +l+ e++++++ tr|Q38BN0|Q38BN0_TRYB2 366 TAVLGALITLQPRAVPLlPGLDAATLIHFTDLLMRpgQRGMTVYKALQQHVPPEVAQYMLQElRTDGALTVLDLTTEEVCKLA 448 **********************************7558999*******************99888888888888888888765 PP >> sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase 7 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.2 0.1 5.2e-09 7.4e-06 25 82 .. 90 151 .. 81 161 .. 0.89 Alignments for each domain: == domain 1 score: 24.2 bits; conditional E-value: 5.2e-09 HH-GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE- CS RrnaAD 25 klnleekltvleigpGkGilTeeLakra.kqvvvlElderLakllqkkls...kdeklkvvh 82 k +++++ vleig+G G+l+ ak k vv++E e+Lakl +++++ ++++kv+h sp|Q582G4|ANM7_TRYB2 90 KKHVTPETGVLEIGAGSGLLSLMAAKLGaKWVVAVEGSEELAKLARENIRannMEHQVKVLH 151 446899********************988******************999888889999987 PP >> tr|Q57WE9|Q57WE9_TRYB2 Protein arginine methyltransferase NDUFAF7 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 4.5e-07 0.00065 25 89 .. 173 248 .. 162 275 .. 0.86 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 4.5e-07 HH-GGTTSEEEEES-TTTCCHHHHHCC-..........SEEEEE-S-HHHHHHHHCHTT.TCCCEEEE-S-CCGHH CS RrnaAD 25 klnleekltvleigpGkGilTeeLakra..........kqvvvlElderLakllqkkls.kdeklkvvhqDflkfe 89 k ++++ l v++ig+G G+l +++++++ ++ v+E+ ++L+++l+++l ++ +k+ + +l++ tr|Q57WE9|Q57WE9_TRYB2 173 KFDPRDPLVVYDIGAGSGALAVSVLDYLsehfpsvyeqCEYHVVEINPQLVQVLRNRLImHYHHVKIHNISILNWR 248 677888999******************9755555554335689*************9998999****999999996 PP >> tr|Q38AH9|Q38AH9_TRYB2 Protein-L-isoaspartate, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.4 0.0 2.4e-06 0.0035 30 86 .. 88 155 .. 69 160 .. 0.74 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 2.4e-06 TTSEEEEES-TTTCCHHHHHCC-....SEEEEE-S-HHHHHHHHCHTT.......TCCCEEEE-S-CC CS RrnaAD 30 ekltvleigpGkGilTeeLakra....kqvvvlElderLakllqkkls.......kdeklkvvhqDfl 86 + tvl++g+G G lT+ La+ + v +E ++L+ + ++ ++ +++++k ++ D+ tr|Q38AH9|Q38AH9_TRYB2 88 KPATVLDVGSGSGYLTAVLAELCsgrgGTVIGVEHISELVVRSTEVVNkhfrswvEEGRIKFIEGDGR 155 6689*******************995556667899999997766655544447777778888887765 PP >> tr|Q57YY7|Q57YY7_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 1.4e-05 0.02 149 254 .. 57 158 .. 53 163 .. 0.82 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 1.4e-05 TTSTT-SHHHHHHHHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS-S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHH CS RrnaAD 149 pgskkrsrlsvlreaftdvklvakveksifsPppkvdsalvelerkdedlpqkdlkkyesvvrkllnrkrktlstslksllpggelq 235 ++k+rs sv +ea ++ ++ +v+k f p s +v+ler++ d ++d+ +y ++++ + + ++++ l+ +++++ + tr|Q57YY7|Q57YY7_TRYB2 57 GNDKRRSLKSVEVEA-NSLSPLCEVDKFQFERLPLTVSEIVRLERRTRD-YVLDVTRYPRILYTVEEETPTEVKGTLELRGERKAIT 141 466777777777776.478999***************************.5*************************99444444433 PP HCTT..T--TTTCCCCSGHH CS RrnaAD 236 alsst.gindnalvkklsae 254 t ++ + l++ ++++ tr|Q57YY7|Q57YY7_TRYB2 142 C---TkSVEGPELIVRCPID 158 3...3379999999888875 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 8561 (4332363 residues searched) Passed MSV filter: 196 (0.0228945); expected 171.2 (0.02) Passed bias filter: 157 (0.018339); expected 171.2 (0.02) Passed Vit filter: 29 (0.00338745); expected 8.6 (0.001) Passed Fwd filter: 6 (0.000700853); expected 0.1 (1e-05) Initial search space (Z): 8561 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.09u 0.00s 00:00:00.09 Elapsed: 00:00:00.04 # Mc/sec: 28701.90 // [ok]