# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/SpoU_methylase.hmm.txt
# target sequence database:        proteomes/Ciona_intestinalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       SpoU_methylase  [M=142]
Accession:   PF00588.18
Description: SpoU rRNA Methylase family
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    5.5e-31  107.5   0.0    9.9e-31  106.7   0.0    1.4  2  tr|F6YVG2|F6YVG2_CIOIN  Uncharacterized protein OS=Ciona inte
  ------ inclusion threshold ------
       0.02   15.0   0.0        1.9    8.5   0.0    2.3  2  tr|F6QCQ5|F6QCQ5_CIOIN  putative methyltransferase C9orf114 O


Domain annotation for each sequence (and alignments):
>> tr|F6YVG2|F6YVG2_CIOIN  Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       1.1     9e+03      65      83 ..      50      68 ..      39      89 .. 0.53
   2 !  106.7   0.0   1.2e-34   9.9e-31       2     141 ..     101     242 ..     100     243 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 1.1
                            HHHHHHHCCCTEEEEEEST CS
          SpoU_methylase 65 eealkelkeegfalvatsl 83
                            +++l++l+ +++  ++ ++
  tr|F6YVG2|F6YVG2_CIOIN 50 RSILRDLNSSNWIAMGSKK 68
                            4445555555443333333 PP

  == domain 2  score: 106.7 bits;  conditional E-value: 1.2e-34
                             EEEEEES-SSHHHHHHHHHHHHHTT-SEEEEESGSSCTCGSHHHHHHCTTHHHHHHEEEES..SHHHHHHHHCCCTEEEEEESTT-S CS
          SpoU_methylase   2 livvlveiedpgNlGaiaRtakafgaselvlvkprsadllnpeakraaagalevlelkvvd..sleealkelkeegfalvatslkgk 86 
                             l++v   i++p NlG + Rt+++fga+++++ +  +    ++ ++ +++ a+++l++ +v+  +lee+l+ +k++g+alvat++ ++
  tr|F6YVG2|F6YVG2_CIOIN 101 LVLVASLIDKPSNLGGLTRTCEVFGAEQMIVHSLSCT--SDKLFQSLSVTAHKWLKMSEVKrwELEEYLESMKRQGYALVATEQTEQ 185
                             6789999*******************99999887776..889999***********9999722568******************888 PP

                             EGC..CSHHHTTEEEEEEBTTTBS-HHHHCTSSEEEE----TTSSS--HHHHHHHHH CS
          SpoU_methylase  87 sls..eidlkekvalvfGnEdkGlsnelleladrlvkIpmsgeveSLNvavAvaill 141
                             s++  e++++ k+++++GnE++G++++ll+ ++ +++Ip+ g v+SLNv+v+ +i +
  tr|F6YVG2|F6YVG2_CIOIN 186 SVCltEYKFPPKCVILLGNEKEGIPPNLLRMCSACIEIPQVGVVRSLNVHVSGGITV 242
                             8888899**********************************************9975 PP

>> tr|F6QCQ5|F6QCQ5_CIOIN  putative methyltransferase C9orf114 OS=Ciona intestinalis OX=7719 GN=LOC100187134 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.0   0.00023       1.9      16      38 ..      84     106 ..      83     121 .. 0.85
   2 ?    3.9   0.0    0.0064        53      60     102 ..     251     299 ..     238     308 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00023
                             HHHHHHHHHTT-SEEEEESGSSC CS
          SpoU_methylase  16 GaiaRtakafgaselvlvkprsa 38 
                             G iaR++ +f+++e+++ ++ + 
  tr|F6QCQ5|F6QCQ5_CIOIN  84 GQIARACVVFQVDEIIVFDESAS 106
                             99***************986554 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.0064
                             EESSHHHHHHHHCCC..T.EEE.EEESTT-SEGCCSHHH..TTEEEEEE CS
          SpoU_methylase  60 vvdsleealkelkee..g.fal.vatslkgkslseidlk..ekvalvfG 102
                              ++sl++a+ ++  +  g +++ ++ts kg+++ +++++  ++ ++vfG
  tr|F6QCQ5|F6QCQ5_CIOIN 251 LANSLSSAIVDCPYSdtGkYDItIGTSDKGEPVADFKMPtfKHLLIVFG 299
                             5667777777766553234666589999******9999999*******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (142 nodes)
Target sequences:                        16678  (5370518 residues searched)
Passed MSV filter:                       361  (0.0216453); expected 333.6 (0.02)
Passed bias filter:                      322  (0.0193069); expected 333.6 (0.02)
Passed Vit filter:                        25  (0.00149898); expected 16.7 (0.001)
Passed Fwd filter:                         2  (0.000119918); expected 0.2 (1e-05)
Initial search space (Z):              16678  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.07u 0.00s 00:00:00.07 Elapsed: 00:00:00.03
# Mc/sec: 25420.45
//
[ok]