# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/SpoU_methylase.hmm.txt
# target sequence database:        proteomes/Ciona_savignyi.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       SpoU_methylase  [M=142]
Accession:   PF00588.18
Description: SpoU rRNA Methylase family
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    2.8e-30  104.7   0.0      6e-30  103.7   0.0    1.5  2  tr|H2YWT1|H2YWT1_CIOSA  Uncharacterized protein OS=Ciona savi
    1.1e-09   38.0   0.0      2e-09   37.2   0.0    1.4  1  tr|H2YFV4|H2YFV4_CIOSA  Uncharacterized protein OS=Ciona savi
    4.2e-05   23.1   0.0    6.2e-05   22.6   0.0    1.3  1  tr|H2YLA3|H2YLA3_CIOSA  Uncharacterized protein OS=Ciona savi
  ------ inclusion threshold ------
      0.014   14.9   0.0        1.1    8.8   0.0    2.3  2  tr|H2YY31|H2YY31_CIOSA  Uncharacterized protein OS=Ciona savi


Domain annotation for each sequence (and alignments):
>> tr|H2YWT1|H2YWT1_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       1.6   4.7e+03      58      85 ..     190     217 ..     181     236 .. 0.62
   2 !  103.7   0.0   2.1e-33     6e-30       2     141 ..     246     387 ..     245     388 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 1.6
                             EEEESSHHHHHHHHCCCTEEEEEESTT- CS
          SpoU_methylase  58 lkvvdsleealkelkeegfalvatslkg 85 
                             +  v+++++ l++lk +++  ++ ++++
  tr|H2YWT1|H2YWT1_CIOSA 190 WIPVQNIRNNLRDLKSSNWVAMGNKKSE 217
                             5567888888888888855555544443 PP

  == domain 2  score: 103.7 bits;  conditional E-value: 2.1e-33
                             EEEEEES-SSHHHHHHHHHHHHHTT-SEEEEESGSSCTCGSHHHHHHCTTHHHHHHEEEES..SHHHHHHHHCCCTEEEEEESTT-S CS
          SpoU_methylase   2 livvlveiedpgNlGaiaRtakafgaselvlvkprsadllnpeakraaagalevlelkvvd..sleealkelkeegfalvatslkgk 86 
                             l++v   i++p NlG + Rt+++fga+++v+ +  ++  +++ ++ +++ a+++l + +v+  +le++l+++k+eg+alvat++ ++
  tr|H2YWT1|H2YWT1_CIOSA 246 LVLVASLIDKPSNLGGLSRTCEVFGAERMVVHNLSCV--NDKLFQSLSVTAHKWLVMSEVKrwDLEKYLEAMKREGYALVATEQTEQ 330
                             6889999************************998888..777777788888888777777522789******************888 PP

                             EGC..CSHHHTTEEEEEEBTTTBS-HHHHCTSSEEEE----TTSSS--HHHHHHHHH CS
          SpoU_methylase  87 sls..eidlkekvalvfGnEdkGlsnelleladrlvkIpmsgeveSLNvavAvaill 141
                             s++  ++++++k+++++GnE++G++++ll+l+d  v+Ip+ g v+SLNv+v+ +i +
  tr|H2YWT1|H2YWT1_CIOSA 331 SVCltQYKFSSKCVVLLGNEKEGIPPNLLRLCDASVEIPQVGVVRSLNVHVSGGITV 387
                             8887799999*******************************************9975 PP

>> tr|H2YFV4|H2YFV4_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.2   0.0   6.8e-13     2e-09       2      62 ..     165     223 ..     164     228 .] 0.87

  Alignments for each domain:
  == domain 1  score: 37.2 bits;  conditional E-value: 6.8e-13
                             EEEEEES-SSHHHHHHHHHHHHHTT-SEEEEESGSSCTCGSHHHHHHCTTHHHHHHEEEES CS
          SpoU_methylase   2 livvlveiedpgNlGaiaRtakafgaselvlvkprsadllnpeakraaagalevlelkvvd 62 
                             l v+l++i dp+N+G+i+Rt+  +g+ e+ ++  ++a +++p++ +a++ga ev++l+  +
  tr|H2YFV4|H2YFV4_CIOSA 165 LWVLLYDIIDPMNIGNILRTCHFLGV-EVPIMTSQCA-PISPTTSKASSGAVEVMQLYSTN 223
                             6799**********************.6666666998.*****************987665 PP

>> tr|H2YLA3|H2YLA3_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.6   0.0   2.2e-08   6.2e-05       2      76 ..      45     117 ..      44     152 .. 0.83

  Alignments for each domain:
  == domain 1  score: 22.6 bits;  conditional E-value: 2.2e-08
                             EEEEEES-SSHHHHHHHHHHHHHTT-SEEEEESGSSCTCGSHHHHHHCTTHHHHHHEEEESSHHHHHHHHCCCTE CS
          SpoU_methylase   2 livvlveiedpgNlGaiaRtakafgaselvlvkprsadllnpeakraaagalevlelkvvdsleealkelkeegf 76 
                             +++++++i+d++ +G ++ +a   g++++++++  +++++n+ +++ aa a++++++   +++e++ k + +e f
  tr|H2YLA3|H2YLA3_CIOSA  45 ITLICDGIKDAKIMGDVLKVALSSGCQQVYVME-GCVNIWNSSVLKRAAAAHFKIPILPNQQWENMEKLVSHE-F 117
                             68999**************************98.9*********************99999999976666655.3 PP

>> tr|H2YY31|H2YY31_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.0   0.00037       1.1      16      38 ..      87     109 ..      86     144 .. 0.83
   2 ?    3.6   0.0     0.016        45      62     102 ..     255     301 ..     244     307 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00037
                             HHHHHHHHHTT-SEEEEESGSSC CS
          SpoU_methylase  16 GaiaRtakafgaselvlvkprsa 38 
                             G iaR++ +f+++e+++ ++ + 
  tr|H2YY31|H2YY31_CIOSA  87 GQIARACVIFQVDEIIVFDESAS 109
                             99***************996554 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.016
                             SSHHHHHHHHCCC..T.EEE.EEESTT-SEGCCSHHH..TTEEEEEE CS
          SpoU_methylase  62 dsleealkelkee..g.fal.vatslkgkslseidlk..ekvalvfG 102
                             +sl++a+ e+  +  g ++l ++ts+kg+++s+++++  ++ ++vfG
  tr|H2YY31|H2YY31_CIOSA 255 NSLSSAIVECPYSdtGkYDLtIGTSEKGNPVSKFKMPkfKHLLIVFG 301
                             55666666655442223555589999******999998899*****9 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (142 nodes)
Target sequences:                        11592  (4231397 residues searched)
Passed MSV filter:                       248  (0.0213941); expected 231.8 (0.02)
Passed bias filter:                      217  (0.0187198); expected 231.8 (0.02)
Passed Vit filter:                        23  (0.00198413); expected 11.6 (0.001)
Passed Fwd filter:                         4  (0.000345066); expected 0.1 (1e-05)
Initial search space (Z):              11592  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.06u 0.00s 00:00:00.06 Elapsed: 00:00:00.03
# Mc/sec: 20028.61
//
[ok]