# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/SpoU_methylase.hmm.txt
# target sequence database:        proteomes/Nematostella_vectensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       SpoU_methylase  [M=142]
Accession:   PF00588.18
Description: SpoU rRNA Methylase family
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    7.9e-30  104.3   0.0    9.1e-30  104.1   0.0    1.0  1  tr|A7RT83|A7RT83_NEMVE  Predicted protein OS=Nematostella vec
    1.5e-28  100.2   0.0    3.5e-28   99.0   0.0    1.6  1  tr|A7SNV9|A7SNV9_NEMVE  Predicted protein OS=Nematostella vec
    4.4e-21   76.0   0.0    1.6e-20   74.2   0.0    1.8  1  tr|A7S341|A7S341_NEMVE  Predicted protein (Fragment) OS=Nemat
  ------ inclusion threshold ------
      0.049   14.2   0.0        0.3   11.7   0.0    1.9  2  tr|A7SKF0|A7SKF0_NEMVE  Predicted protein (Fragment) OS=Nemat


Domain annotation for each sequence (and alignments):
>> tr|A7RT83|A7RT83_NEMVE  Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g92540 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.1   0.0   1.5e-33   9.1e-30       2     141 ..      12     153 ..      11     154 .. 0.95

  Alignments for each domain:
  == domain 1  score: 104.1 bits;  conditional E-value: 1.5e-33
                             EEEEEES-SSHHHHHHHHHHHHHTT-SEEEEESGSSCTCGSHHHHHHCTTHHHHHHEEEE..SSHHHHHHHHCCCTEEEEEEST..T CS
          SpoU_methylase   2 livvlveiedpgNlGaiaRtakafgaselvlvkprsadllnpeakraaagalevlelkvv..dsleealkelkeegfalvatsl..k 84 
                             l+vv   i+++ NlG ++Rt+++fga++lvl + +++ +++p +k +++++ +++++++v  ++l+++l+++++ g+ l+++++  +
  tr|A7RT83|A7RT83_NEMVE  12 LVVVASLINKAPNLGGLCRTCEIFGAKRLVLGS-NEV-MNDPYFKGLSVSSSKWVDIEQVrpAELNNYLDAMRHDGYSLIGVEQtaN 96 
                             799****************************66.666.8*****************99987789******************99889 PP

                             -SEGCCSHHHTTEEEEEEBTTTBS-HHHHCTSSEEEE----TTSSS--HHHHHHHHH CS
          SpoU_methylase  85 gkslseidlkekvalvfGnEdkGlsnelleladrlvkIpmsgeveSLNvavAvaill 141
                             +k+l++++++ k++l++GnE++G++ el++++d +v+Ip+ g ++SLNv+v+ a+l+
  tr|A7RT83|A7RT83_NEMVE  97 SKRLTDFTFPHKTLLLLGNEKEGIPVELIQQLDACVEIPQVGVIRSLNVHVSGALLI 153
                             99****************************************************987 PP

>> tr|A7SNV9|A7SNV9_NEMVE  Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g215116 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.0   0.0   5.7e-32   3.5e-28       2     141 ..     129     283 ..     128     284 .. 0.85

  Alignments for each domain:
  == domain 1  score: 99.0 bits;  conditional E-value: 5.7e-32
                             EEEEEES-SSHHHHHHHHHHHHHTT-SEEEEESGSSCTCGSHHHHHHCTTHHHHHHEEEESSHHHHHHHHCCCTEEEEEEST...T- CS
          SpoU_methylase   2 livvlveiedpgNlGaiaRtakafgaselvlvkprsadllnpeakraaagalevlelkvvdsleealkelkeegfalvatsl...kg 85 
                             l+++l+ei+dp+N+Gai+Rt   +g++++v+ k++sa +l+p + +a+aga ev+++++ ++l ++l+e    g++++++ +   + 
  tr|A7SNV9|A7SNV9_NEMVE 129 LVLALDEIQDPMNFGAIIRTSWLLGVDKIVVPKQNSA-PLSPVVSKASAGAMEVFNVYQTPDLPKFLQERAAIGWDVLGAVQpitD- 213
                             789****************************998887.****************************************99877742. PP

                             SEGC......CSHHHTTEEEEEEBTTTBS-HHHHCTSSEEEE--........--TTSSS--HHHHHHHHH CS
          SpoU_methylase  86 ksls......eidlkekvalvfGnEdkGlsnelleladrlvkIp........msgeveSLNvavAvaill 141
                             +s +      e++l+++++lv+GnE++Gl+n + +++++l++I         +s + +S+Nv+vA++il+
  tr|A7SNV9|A7SNV9_NEMVE 214 DSHHrpvncaEYSLSKPTVLVLGNEGRGLRNTVQQQCTQLLSIYphqaqnsfQSIDLDSFNVSVAAGILV 283
                             332234446677888****************************62222222233456899********86 PP

>> tr|A7S341|A7S341_NEMVE  Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g25116 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.2   0.0   2.5e-24   1.6e-20       2     142 .]      91     268 ..      90     268 .. 0.82

  Alignments for each domain:
  == domain 1  score: 74.2 bits;  conditional E-value: 2.5e-24
                             EEEEEES-SSHHHHHHHHHHHHHTT-SEEEEESGSSCTCGSHHHHHHCTTHHHHHHEEEESSHHHHHHHHCCCTEEEEEEST..T-S CS
          SpoU_methylase   2 livvlveiedpgNlGaiaRtakafgaselvlvkprsadllnpeakraaagalevlelkvvdsleealkelkeegfalvatsl..kgk 86 
                             l+v++++++dp NlG+i+Rt++a+g+++l+ ++  s dl++p+++r +ag ++ ++l+   s++++ + l +  ++l+ +++   gk
  tr|A7S341|A7S341_NEMVE  91 LTVICDRVKDPSNLGTIVRTCAAAGCQALITTE-YSTDLWDPKVLRGGAGGHFRVPLYGLLSWKQIADMLGDD-TRLYLAESdnTGK 175
                             78************************9999988.8889****************************9999999.8888887755555 PP

                             EGC...CS.......HHH.......................TTEEEEEEBTTTBS-HHHHCTSS....EEEE----TTSSS--HHHH CS
          SpoU_methylase  87 sls...ei.......dlk.......................ekvalvfGnEdkGlsnellelad....rlvkIpmsgeveSLNvavA 136
                              +    ++       +++                       ++ al++G E++G+s+e+  la     + v+Ipm g+++SL    +
  tr|A7S341|A7S341_NEMVE 176 IIIspwKYfvvenpiSWHcygtlnldlgsiiipyfevdwtlGPSALIVGGETTGISTEAQMLACgergQAVHIPMVGNIDSLSAGIS 262
                             4434442244444452226666666677777777788888****************99876653345579***************** PP

                             HHHHHH CS
          SpoU_methylase 137 vailly 142
                             va+++y
  tr|A7S341|A7S341_NEMVE 263 VALIVY 268
                             **9988 PP

>> tr|A7SKF0|A7SKF0_NEMVE  Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g121512 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   4.9e-05       0.3      16      71 ..      29      86 ..      28      96 .. 0.79
   2 ?   -0.2   0.0      0.22   1.4e+03      64     102 ..     202     244 ..     176     254 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 4.9e-05
                            HHHHHHHHHTT-SEEEEESGSSCTCGSHH..HHHHCTTHHHHHHEEEESSHHHHHHHH CS
          SpoU_methylase 16 GaiaRtakafgaselvlvkprsadllnpe..akraaagalevlelkvvdsleealkel 71
                            G iaR++ +f+++e+++ ++ +++l++++  + ++ ++a   l+l+++ ++ e+ + l
  tr|A7SKF0|A7SKF0_NEMVE 29 GQIARAVVVFNVDEVIVFNESRKSLDKSKdgVSNFHSKADANLQLARILQYLECPQYL 86
                            99*****************988777666666888888888888877666666655555 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.22
                             HHHHHHHHCCC.TEEE.EEESTT-SEGCCSHHH..TTEEEEEE CS
          SpoU_methylase  64 leealkelkee.gfal.vatslkgkslseidlk..ekvalvfG 102
                             ++++++e     g+++ ++ts++g +++ ++l+  +++++vfG
  tr|A7SKF0|A7SKF0_NEMVE 202 FSDVFTESPYPqGYDVmIGTSERGAPVDCLELQpfSHMLIVFG 244
                             5555444443326777688888999999666666699999999 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (142 nodes)
Target sequences:                        24428  (8257945 residues searched)
Passed MSV filter:                       445  (0.0182168); expected 488.6 (0.02)
Passed bias filter:                      399  (0.0163337); expected 488.6 (0.02)
Passed Vit filter:                        37  (0.00151466); expected 24.4 (0.001)
Passed Fwd filter:                         4  (0.000163747); expected 0.2 (1e-05)
Initial search space (Z):              24428  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.11u 0.01s 00:00:00.12 Elapsed: 00:00:00.06
# Mc/sec: 19543.80
//
[ok]