# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/SpoU_methylase.hmm.txt
# target sequence database:        proteomes/Saccharomyces_cerevisiae.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       SpoU_methylase  [M=142]
Accession:   PF00588.18
Description: SpoU rRNA Methylase family
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence             Description
    ------- ------ -----    ------- ------ -----   ---- --  --------             -----------
    2.2e-26   91.2   0.0    4.6e-26   90.2   0.0    1.6  1  sp|Q07527|TRM3_YEAST  tRNA (guanosine(18)-2'-O)-methyltransfe
    6.1e-26   89.8   0.0    2.6e-25   87.7   0.0    2.0  1  sp|P25270|MRM1_YEAST  rRNA methyltransferase 1, mitochondrial


Domain annotation for each sequence (and alignments):
>> sp|Q07527|TRM3_YEAST  tRNA (guanosine(18)-2'-O)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.2   0.0   1.5e-29   4.6e-26       2     141 ..    1286    1428 ..    1285    1429 .. 0.94

  Alignments for each domain:
  == domain 1  score: 90.2 bits;  conditional E-value: 1.5e-29
                            EEEEEES-SSHHHHHHHHHHHHHTT-SEEEEESGSSCTCGSHHHHHHCTTHHHHHHEEEE..SSHHHHHHHHCCCTEEEEEESTT-S CS
        SpoU_methylase    2 livvlveiedpgNlGaiaRtakafgaselvlvkprsadllnpeakraaagalevlelkvv..dsleealkelkeegfalvatslkgk 86  
                            livv   +++p NlG i+R+++++g+ +l+ v++ ++  ++p++k++a+ a  ++++++v  d++++++ke k+eg++l+++++ +k
  sp|Q07527|TRM3_YEAST 1286 LIVVSSLVDKPPNLGGICRLCDVLGV-GLLTVQDIKV-KNHPQFKNVAVTADRWMPMEEValDEIASFMKEKKKEGYTLIGLEQTDK 1370
                            7899999*******************.8888887887.9*****************9988779*********************999 PP

                            EGC...CSHHHTTEEEEEEBTTTBS-HHHHCTSSEEEE----TTSSS--HHHHHHHHH CS
        SpoU_methylase   87 sls...eidlkekvalvfGnEdkGlsnelleladrlvkIpmsgeveSLNvavAvaill 141 
                            s++   ++++++k ++++G+E  G++  ll+++d +++I + g ++S+N+++A+a+++
  sp|Q07527|TRM3_YEAST 1371 SVKldnNFQFPKKSLILLGTEAFGIPGTLLSELDLCLEIQQFGVIRSMNIQTATAVIV 1428
                            88887899************************************************97 PP

>> sp|P25270|MRM1_YEAST  rRNA methyltransferase 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.7   0.0   8.6e-29   2.6e-25       4     141 ..     244     405 ..     241     406 .. 0.80

  Alignments for each domain:
  == domain 1  score: 87.7 bits;  conditional E-value: 8.6e-29
                           EEEES-SSHHHHHHHHHHHHHTT-SEEEEESGSSCTCGSHHHHHHCTTHHHHHHEEEESSHHHHHHHHCCCTEEEEEEST..T-SEGC. CS
        SpoU_methylase   4 vvlveiedpgNlGaiaRtakafgaselvlvkprsadllnpeakraaagalevlelkvvdsleealkelkeegfalvatsl..kgksls. 89 
                           ++l+ei+dp+N+Gai+R+a+ +g++ +v++++++ ++l+p + ++++gale+l++ +vd+  e++++ +e g +++ ts+  +   +s 
  sp|P25270|MRM1_YEAST 244 LYLDEITDPHNIGAIIRSAYFLGVDFIVMSRRNC-SPLTPVVSKTSSGALELLPIFYVDKPLEFFTKSQEMGGWTFITSHlaN--ATSe 329
                           79**********************8888877666.6***********************************999999988543..3332 PP

                           CS.......HHH........TTEEEEEEBTTTBS-HHHHCTSSEEEE----TT..........SSS--HHHHHHHHH CS
        SpoU_methylase  90 ei.......dlk........ekvalvfGnEdkGlsnelleladrlvkIpmsge..........veSLNvavAvaill 141
                           ++         +         +v+lv+GnE++G++++l  + d +v+Ip  g           v+SLNv+vA+a+l+
  sp|P25270|MRM1_YEAST 330 KYtvgktisM-HdlnglcneLPVVLVVGNESQGVRTNLKMRSDFFVEIPFGGIekgnrapepiVDSLNVSVATALLI 405
                           2233443440.2555777779****************************7532222233333389*********986 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (142 nodes)
Target sequences:                         6049  (2936363 residues searched)
Passed MSV filter:                       119  (0.0196727); expected 121.0 (0.02)
Passed bias filter:                      101  (0.016697); expected 121.0 (0.02)
Passed Vit filter:                        13  (0.00214912); expected 6.0 (0.001)
Passed Fwd filter:                         2  (0.000330633); expected 0.1 (1e-05)
Initial search space (Z):               6049  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.05u 0.00s 00:00:00.05 Elapsed: 00:00:00.02
# Mc/sec: 20848.18
//
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