# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TRM.hmm.txt
# target sequence database:        proteomes/Amphimedon_queenslandica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TRM  [M=376]
Accession:   PF02005.15
Description: N2,N2-dimethylguanosine tRNA methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence                       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------                       -----------
   3.5e-128  429.2   0.0   4.5e-128  428.9   0.0    1.0  1  tr|A0A1X7UT60|A0A1X7UT60_AMPQE  tRNA (guanine(26)-N(2))-dimethyl
    2.3e-31  110.6   0.0    2.6e-31  110.4   0.0    1.0  1  tr|A0A1X7SIB7|A0A1X7SIB7_AMPQE  Uncharacterized protein OS=Amphi
    3.6e-05   24.4   0.0    7.6e-05   23.3   0.0    1.5  1  tr|A0A1X7VCI4|A0A1X7VCI4_AMPQE  Uncharacterized protein OS=Amphi
  ------ inclusion threshold ------
       0.28   11.6   0.0       0.41   11.0   0.0    1.2  1  tr|A0A1X7UNT6|A0A1X7UNT6_AMPQE  Uncharacterized protein OS=Amphi
       0.37   11.2   0.0        0.6   10.5   0.0    1.3  1  tr|A0A1X7VVN5|A0A1X7VVN5_AMPQE  Uncharacterized protein OS=Amphi


Domain annotation for each sequence (and alignments):
>> tr|A0A1X7UT60|A0A1X7UT60_AMPQE  tRNA (guanine(26)-N(2))-dimethyltransferase OS=Amphimedon queenslandica OX=400682 PE=
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  428.9   0.0  5.2e-132  4.5e-128       8     376 .]      53     482 ..      45     482 .. 0.92

  Alignments for each domain:
  == domain 1  score: 428.9 bits;  conditional E-value: 5.2e-132
                                     ----SS--TT--SS--GGGHHHHHHHHHH...HHHHHHHH-S-.................................... CS
                             TRM   8 edkevtvskkeeVFYNPvqefnRDlsvlvirqlellkkklgek.................................... 50 
                                      ++ + v+k++ VFYNPvq fnRDls++v+ q + +  +   +                                    
  tr|A0A1X7UT60|A0A1X7UT60_AMPQE  53 GKARMFVPKQNSVFYNPVQVFNRDLSLAVVDQYAKKYWRY--Hhrqkrpfwradsglianekkpnepaepaksdssnne 129
                                     3444779**********************85322222222..1224578****************************** PP

                                     .....EEEEESS-TTSHHHHHHHHH-S-E.EEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC...--SS- CS
                             TRM  51 .....ikvldaLsasGlRaiRfalEvpgv.kevlaNDisekAvelikeNvklneveeivvineddAnvlla...ekkkr 120
                                          +k+l+aL+asGlR+iR+alE++++  e+ aND s+ A+++i  N+k n v++iv+++ +dA++l++   e  ++
  tr|A0A1X7UT60|A0A1X7UT60_AMPQE 130 pdrpkLKILEALAASGLRSIRYALEIQSTpCEITANDYSSDAYQSITDNAKRNGVSKIVQPSCKDARLLMYehiEPLEQ 208
                                     **************************976369***************************************7766779* PP

                                     EEEEEE--SS--GGGHHHHHHHEEEEEEEEEEE--HHHHTTSSHHHHHHHHSSB---STTHHHHHHHHHHHHHHHHHHT CS
                             TRM 121 fdviDlDPfGspapfldsavqsvkekglLlvTaTDtavLaGaspekclrkYgavalkselcHEvalRillkavareaak 199
                                     f+v+D+DP+Gs+a fldsavq++k++glL+vT+TD +vL+G+  e c++kYg+v+lk+++cHE++lRi+l +++++a +
  tr|A0A1X7UT60|A0A1X7UT60_AMPQE 209 FHVVDIDPYGSAAVFLDSAVQCIKDGGLLCVTCTDASVLCGNRSEVCFSKYGSVSLKTKYCHEMGLRIILASLNSHAGR 287
                                     ******************************************************************************* PP

                                     TTEEEEEEEEEEETTEEEEEEEEEE-HHHHHHHHTTEEEEEEETTT..........--EEEE--GGG--.......SB- CS
                             TRM 200 YekavepllslsadfYvrvfvkvktgaakvkkvleklglvlhCsgC..........lseekvkglakfk.......aec 261
                                     Y+++++p+lsls+dfY+rvfv + t++ +vkk+++kl +v+hC gC          ls+ k +++++ +       ++c
  tr|A0A1X7UT60|A0A1X7UT60_AMPQE 288 YQRYIHPILSLSTDFYFRVFVTIYTSPLEVKKSASKLSMVYHCDGCssfhlqplikLSTTKDNSIKTHSsfgppinKDC 366
                                     **********************************************9999999988666666777766688899999** PP

                                     TTT-SBEEEEEEEE-S-S--HHHHHHHHHHHCT..-TTS.-HHHHHHHHHHHHHHS--SS-EEHHHHHHHHT-SS---H CS
                             TRM 262 ehcgaklhlaGPlwlgplkdkefveevleeaekekeeel.kkrvkklLklikeElldaplyydlsqlasvlklsvpplk 339
                                     ehc+++++++GP+w +p++d  f+ ++l  ++++k+    + ++ ++L+++keEl ++p+++dlsql+svl+++v ++ 
  tr|A0A1X7UT60|A0A1X7UT60_AMPQE 367 EHCSSNFKFGGPVWSDPIHDDIFISSLLSDLQETKDCFAtNSKMIGMLSMMKEELNNVPFFHDLSQLSSVLHCNVMRML 445
                                     *********************************8754446999************************************ PP

                                     HHHHHH....TT-EE-TTSTTEEE-SS-HHHHHHHHH CS
                             TRM 340 kvvsalkelgfevsrtHakpkaikTnapleavvevlr 376
                                     +++sal + g++vs +H++p+a+kT+ap ++v++++r
  tr|A0A1X7UT60|A0A1X7UT60_AMPQE 446 EMRSALMNQGYRVSSSHTNPQAVKTDAPHSVVWDIMR 482
                                     ************************************7 PP

>> tr|A0A1X7SIB7|A0A1X7SIB7_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.4   0.0   2.9e-35   2.6e-31     259     376 .]       3     121 ..       1     121 [. 0.95

  Alignments for each domain:
  == domain 1  score: 110.4 bits;  conditional E-value: 2.9e-35
                                     SB-TTT-SBEEEEEEEE-S-S--HHHHHHHHHHHCT..-TTS.-HHHHHHHHHHHHHHS--SS-EEHHHHHHHHT-SS- CS
                             TRM 259 aecehcgaklhlaGPlwlgplkdkefveevleeaekekeeel.kkrvkklLklikeElldaplyydlsqlasvlklsvp 336
                                     ++cehc+++++++GP+w +p++d  f+ ++l  ++++k++   + ++ ++L+++keEl ++p+++dlsql+svl+++v 
  tr|A0A1X7SIB7|A0A1X7SIB7_AMPQE   3 KDCEHCSSNFKFGGPVWSDPIHDDIFISSLLSDLQETKDRFAtNSKMIGMLSMMKEELNNVPFFHDLSQLSSVLHCNVM 81 
                                     68**********************************8654446999********************************* PP

                                     --HHHHHHH....TT-EE-TTSTTEEE-SS-HHHHHHHHH CS
                             TRM 337 plkkvvsalkelgfevsrtHakpkaikTnapleavvevlr 376
                                     ++ +++sal + g+ vs +H++p+a+kT+ap ++v++++r
  tr|A0A1X7SIB7|A0A1X7SIB7_AMPQE  82 RMLEMRSALMNQGYGVSSSHTNPQAVKTDAPHSVVWDIMR 121
                                     ***************************************7 PP

>> tr|A0A1X7VCI4|A0A1X7VCI4_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.3   0.0   8.7e-09   7.6e-05      39     124 ..     122     209 ..      94     217 .. 0.83

  Alignments for each domain:
  == domain 1  score: 23.3 bits;  conditional E-value: 8.7e-09
                                     .HH.HHHHHH-S-EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC. CS
                             TRM  39 qle.llkkklgekikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvineddAnvlla. 115
                                      l+ l+++++ +k+  l+   +sG  ++  ++E ++  + +a Di++kAvel keN+  nev++++ + ++  + l++ 
  tr|A0A1X7VCI4|A0A1X7VCI4_AMPQE 122 ILNfLQNHHCRQKLDFLELCCGSGAISVSLLKE-NESLSGYATDILPKAVELTKENSIRNEVDQRLIVTKAPITDLMSd 199
                                     333134456789*********************.8888999**********************9888888899999998 PP

                                     .--SS-EEEE CS
                             TRM 116 .ekkkrfdvi 124
                                      e ++rfd+i
  tr|A0A1X7VCI4|A0A1X7VCI4_AMPQE 200 tELESRFDFI 209
                                     8889999998 PP

>> tr|A0A1X7UNT6|A0A1X7UNT6_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   4.7e-05      0.41     309     366 ..     150     211 ..     127     216 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 4.7e-05
                                     HHHHHHH.S--SS-EEH.HHHHHHHT-SS---HHHHHHH....TT-..EE-TTSTTEEE-SS CS
                             TRM 309 klikeEl.ldaplyydl.sqlasvlklsvpplkkvvsalkelgfev..srtHakpkaikTna 366
                                     ++++ E  l++ ++y++ s+ +++l+ + pp++ + + l ++gf+v  +++H++++ ik + 
  tr|A0A1X7UNT6|A0A1X7UNT6_AMPQE 150 NTLTSEQlLESYFMYKIvSKASERLSEKYPPVSVLHDRLSKIGFRVqsVLAHCHESIIKMDT 211
                                     455555448999999863788899********************9844689*******9986 PP

>> tr|A0A1X7VVN5|A0A1X7VVN5_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   6.9e-05       0.6     261     327 ..      72     140 ..      19     153 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 6.9e-05
                                     -TTT-SBEEEEEEEE-S-S--HHHHHHHHHHHCT....-TTS-HHHHHHHHHHHHHHS--SS-EEHHHH CS
                             TRM 261 cehcgaklhlaGPlwlgplkdkefveevleeaekek..eeelkkrvkklLklikeElldaplyydlsql 327
                                      + +++ ++  GP++ g +  kef++ +++ ++ ++  ++ +++r+++l++   +    +p    ++++
  tr|A0A1X7VVN5|A0A1X7VVN5_AMPQE  72 LTVLETCVKNCGPMFHGRIATKEFLKDLTNVIQPKNnpPTIVRERILGLIQYWADAFKANPELAAVNEV 140
                                     45566777889******************9988765424445*******99887776666665555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (376 nodes)
Target sequences:                        43435  (14716620 residues searched)
Passed MSV filter:                      1486  (0.034212); expected 868.7 (0.02)
Passed bias filter:                      941  (0.0216646); expected 868.7 (0.02)
Passed Vit filter:                        69  (0.00158858); expected 43.4 (0.001)
Passed Fwd filter:                         5  (0.000115115); expected 0.4 (1e-05)
Initial search space (Z):              43435  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.41u 0.01s 00:00:00.42 Elapsed: 00:00:00.13
# Mc/sec: 42564.99
//
[ok]