# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/TRM.hmm.txt
# target sequence database: proteomes/Anolis_carolinensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: TRM [M=376]
Accession: PF02005.15
Description: N2,N2-dimethylguanosine tRNA methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
8.7e-142 472.8 0.0 1.1e-141 472.5 0.0 1.0 1 tr|H9G883|H9G883_ANOCA tRNA (guanine(26)-N(2))-dimethyltrans
3.8e-67 227.1 5.1 2.8e-57 194.7 1.2 3.1 3 tr|H9G676|H9G676_ANOCA tRNA methyltransferase 1 like OS=Anol
5.4e-05 22.6 0.1 8.2e-05 22.0 0.1 1.5 1 tr|H9GBK0|H9GBK0_ANOCA tRNA (guanine(37)-N1)-methyltransfera
------ inclusion threshold ------
0.046 12.9 0.0 0.073 12.3 0.0 1.2 1 tr|G1KMS3|G1KMS3_ANOCA Uncharacterized protein OS=Anolis car
Domain annotation for each sequence (and alignments):
>> tr|H9G883|H9G883_ANOCA tRNA (guanine(26)-N(2))-dimethyltransferase OS=Anolis carolinensis OX=28377 GN=TRMT1 PE=3 SV=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 472.5 0.0 2.3e-145 1.1e-141 4 376 .] 41 485 .. 38 485 .. 0.92
Alignments for each domain:
== domain 1 score: 472.5 bits; conditional E-value: 2.3e-145
EEEE----SS--TT--SS--GGGHHHHHHHHHH........HHHHHHHH-S-................................... CS
TRM 4 kikvedkevtvskkeeVFYNPvqefnRDlsvlvi....r.qlellkkklgek................................... 50
i++ ++ ++++ ++eVFYNPvqefnRDl+++vi r ql+ ++ +l+ +
tr|H9G883|H9G883_ANOCA 41 LITEGKARIIFPCANEVFYNPVQEFNRDLTCAVItefaRlQLSSKGIRLAVPgeensskvvadlskeekddnleqhpsddqlqeegh 127
4555556699***********************9555444455555555555*********************************** PP
............EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC...--SS-EE CS
TRM 51 ............ikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvineddAnvlla...ekkkrfd 122
++vl+aL+asGlR+iRfa+Evpg ++v+aND+s+kAveli +Nv+ln+v ++v+++ +dA+++++ + k fd
tr|H9G883|H9G883_ANOCA 128 kvaavgqvcqdgLRVLEALAASGLRSIRFAKEVPGLRSVVANDFSSKAVELITQNVQLNDVGHLVTPSFSDARMVMYqckADKALFD 214
*****************************************************************************88777889** PP
EEEE--SS--GGGHHHHHHHEEEEEEEEEEE--HHHHTTSSHHHHHHHHSSB---STTHHHHHHHHHHHHHHHHHHTTTEEEEEEEE CS
TRM 123 viDlDPfGspapfldsavqsvkekglLlvTaTDtavLaGaspekclrkYgavalkselcHEvalRillkavareaakYekaveplls 209
viDlDP+Gsp++fld+avq+v+e+glL+vT+TD+av+aG+s e+c++kYga+++k ++cHE+alRi+l++++ +a++Y+++++plls
tr|H9G883|H9G883_ANOCA 215 VIDLDPYGSPSTFLDAAVQAVSEGGLLCVTCTDMAVMAGNSGETCYSKYGAMSIKARFCHEMALRIILHSLDLRANCYQRYIVPLLS 301
*************************************************************************************** PP
EEETTEEEEEEEEEE-HHHHHHHHTTEEEEEEETTT..........--EEEE--GGG--........SB-TTT-SBEEEEEEEE-S- CS
TRM 210 lsadfYvrvfvkvktgaakvkkvleklglvlhCsgC..........lseekvkglakfk........aecehcgaklhlaGPlwlgp 278
+s+dfY+rv+v+v t + kvk++++k++lv++C+gC + ++ ++ ++k cehc ++++laGP+w++p
tr|H9G883|H9G883_ANOCA 302 VSVDFYIRVYVRVFTAQSKVKASASKQALVYNCVGCgsfhiqrlgkMAHNGNN--INYKaacgppvgPSCEHCHQRHQLAGPFWAEP 386
************************************99887776552222222..222255789999******************** PP
S--HHHHHHHHHHHCT...-TTS-HHHHHHHHHHHHHHS--SS-EEHHHHHHHHT-SS---HHHHHHH....TT-EE-TTSTTEEE- CS
TRM 279 lkdkefveevleeaekek.eeelkkrvkklLklikeElldaplyydlsqlasvlklsvpplkkvvsalkelgfevsrtHakpkaikT 364
l+d +fv++vl ++ ++ + ++ +r++++L+++ eEl+d+plyy+l++l++++++s+p+l +++sal+++g++vs++Ha+++aikT
tr|H9G883|H9G883_ANOCA 387 LHDMAFVQQVLSAVGSNPgRFQTGQRIQGILSMALEELSDVPLYYTLDNLSKTVHCSSPSLLQFRSALLHAGYRVSLSHACKSAIKT 473
***************9754445599************************************************************** PP
SS-HHHHHHHHH CS
TRM 365 napleavvevlr 376
+ap +v++++r
tr|H9G883|H9G883_ANOCA 474 DAPPPVVWDIMR 485
**********97 PP
>> tr|H9G676|H9G676_ANOCA tRNA methyltransferase 1 like OS=Anolis carolinensis OX=28377 GN=TRMT1L PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.3 0.1 0.44 2e+03 228 250 .. 172 207 .. 168 237 .. 0.64
2 ! 194.7 1.2 6e-61 2.8e-57 12 311 .. 240 561 .. 222 585 .. 0.85
3 ! 32.5 0.0 1.1e-11 5.3e-08 316 374 .. 626 684 .. 603 686 .. 0.82
Alignments for each domain:
== domain 1 score: -2.3 bits; conditional E-value: 0.44
HHHHHHTTEEEEEEETTT.............--EEE CS
TRM 228 kvkkvleklglvlhCsgC.............lseek 250
++ + k+g +hC C +++++
tr|H9G676|H9G676_ANOCA 172 TADPISAKMGSHYHCLICsatigrrtdmighVKRHV 207
567788899999******766655544444322222 PP
== domain 2 score: 194.7 bits; conditional E-value: 6e-61
SS--TT--SS--GGGHHHHHHHHHH...HHHHHHHH-S-EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT CS
TRM 12 vtvskkeeVFYNPvqefnRDlsvlvirqlellkkklgekikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklne 98
t ++k++ ++NP ++ nR l+v + l++l ++ ++++ lda+ a+G+ ++ +a+ + + +v +ND +ek v +i+eN +ln+
tr|H9G676|H9G676_ANOCA 240 YTTPQKTDSYFNPKMKLNRQLTVCA---LAVLAEE-RKPLECLDAFGATGIMGLQWAKHLGNSVKVTINDYNEKSVTMIQENCHLNK 322
457899999****************...7777777.689*******************************************88888 PP
--......................GGEEEE-S-HHHHHC--SS-EEEEEE--SS--GGGHHHHHHHEEEEEEEEEEE--HHHHTTSS CS
TRM 99 ve......................eivvineddAnvllaekkkrfdviDlDPfGspapfldsavqsvkekglLlvTaTDtavLaGas 163
++ ++++ ++dAnv++ + ++fd+i lDPfGs++++ld+a + v++ g+++vT+TD ++L ++
tr|H9G676|H9G676_ANOCA 323 MKvvmnlreeedcdeaveeveenlPVIEVTKMDANVIM--HLRAFDFIHLDPFGSSVNYLDAAFRNVRNLGIVSVTSTDISSLYSKA 407
77777888888898888888875448999*********..889******************************************** PP
HHHHHHHHSSB---STTHHHHHHHHHHHHHHHHHHTTTEEEEEEEEEEETTEEEEEEEEEE-HHHHHHHHTTEEEEEEETTT..... CS
TRM 164 pekclrkYgavalkselcHEvalRillkavareaakYekavepllslsadfYvrvfvkvktgaakvkkvleklglvlhCsgC..... 245
++ r+Yg++ +++e++ E a R+++ avar+aa+ +k +e+ll+++ +++v v v+v +g+ ++++++k+ +++hC C
tr|H9G676|H9G676_ANOCA 408 QHVAQRHYGSNIVRTEYYKELAARMIIAAVARAAARCNKGIEVLLAVALEHFVLVEVRVLRGPSPADDTAKKIRYLIHCQWCeervf 494
**********************************************************************************55544 PP
.....--EEEE--GGG--........SB-TTT-SBEEEEEEEE-S-S--HHHHHHHHHHHCT..-TTS.-HHHHHHHHHH CS
TRM 246 .....lseekvkglakfk........aecehcgaklhlaGPlwlgplkdkefveevleeaekekeeel.kkrvkklLkli 311
+ + + + g++ GPlw g l ++ f+ ++l ea + + ++++ lLk++
tr|H9G676|H9G676_ANOCA 495 kkegnM-----IEE---NpyrqlpcdCHSRMTGKTAIELGPLWSGSLFNTGFLRRMLFEAVQ-----YgLEDIQPLLKTL 561
222221.....222...2344555334445556666678*****************998887.....3256666666654 PP
== domain 3 score: 32.5 bits; conditional E-value: 1.1e-11
S--SS-EEHHHHHHHHT-SS---HHHHHHH....TT-EE-TTSTTEEE-SS-HHHHHHH CS
TRM 316 ldaplyydlsqlasvlklsvpplkkvvsalkelgfevsrtHakpkaikTnapleavvev 374
++p +y + s+ +++p+l+k+ + l e+g++vsrtH+ p +++Tnapl ++ +
tr|H9G676|H9G676_ANOCA 626 AEHPSFYYNIHRHSIKGMNMPKLNKFLHYLSEAGYRVSRTHFDPMGVRTNAPLVQFKSI 684
44555555555578899***********************************9887666 PP
>> tr|H9GBK0|H9GBK0_ANOCA tRNA (guanine(37)-N1)-methyltransferase OS=Anolis carolinensis OX=28377 GN=TRMT5 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.0 0.1 1.8e-08 8.2e-05 53 115 .. 303 362 .. 92 371 .. 0.86
Alignments for each domain:
== domain 1 score: 22.0 bits; conditional E-value: 1.8e-08
EEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC CS
TRM 53 vldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvineddAnvlla 115
++d +++ G ai a+ v+aND++++ ++ +++N kln+v+ v++ ++d + +++
tr|H9GBK0|H9GBK0_ANOCA 303 LFDVFAGVGPFAIPAAKK---NCIVFANDLNPESYKWLQRNCKLNKVDTKVQVFNMDGREFMK 362
567777777777777766...5579***********************99999999*****98 PP
>> tr|G1KMS3|G1KMS3_ANOCA Uncharacterized protein OS=Anolis carolinensis OX=28377 GN=etfbkmt PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.3 0.0 1.6e-05 0.073 44 100 .. 112 166 .. 104 183 .. 0.83
Alignments for each domain:
== domain 1 score: 12.3 bits; conditional E-value: 1.6e-05
HHHH-S-EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT-- CS
TRM 44 kkklgekikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneve 100
+ k++++ kvld s+ G ai ++g+++v+aNDi + A + N +ln+v+
tr|G1KMS3|G1KMS3_ANOCA 112 NPKVVRRKKVLDLGSGCGATAIAAM--MSGASQVVANDIDPVAAAATVLNCELNNVN 166
5567777789998888888888655..56**************************98 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (376 nodes)
Target sequences: 18528 (9796552 residues searched)
Passed MSV filter: 670 (0.0361615); expected 370.6 (0.02)
Passed bias filter: 462 (0.0249352); expected 370.6 (0.02)
Passed Vit filter: 45 (0.00242876); expected 18.5 (0.001)
Passed Fwd filter: 9 (0.000485751); expected 0.2 (1e-05)
Initial search space (Z): 18528 [actual number of targets]
Domain search space (domZ): 4 [number of targets reported over threshold]
# CPU time: 0.38u 0.02s 00:00:00.40 Elapsed: 00:00:00.13
# Mc/sec: 28334.64
//
[ok]