# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TRM.hmm.txt
# target sequence database:        proteomes/Dictyostelium_discoideum.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TRM  [M=376]
Accession:   PF02005.15
Description: N2,N2-dimethylguanosine tRNA methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
     3e-125  417.8   0.2   4.1e-125  417.4   0.2    1.1  1  tr|Q54PG3|Q54PG3_DICDI  tRNA (guanine(26)-N(2))-dimethyltrans
    3.2e-06   26.1   0.1    6.4e-06   25.1   0.1    1.5  1  sp|Q54WD6|TRM5_DICDI    tRNA (guanine(37)-N1)-methyltransfera
  ------ inclusion threshold ------
      0.016   13.9   0.3      0.027   13.2   0.3    1.4  1  sp|Q86JB0|Y8324_DICDI   Putative uncharacterized protein DDB_
      0.068   11.8   0.0        0.1   11.3   0.0    1.2  1  tr|Q54PP5|Q54PP5_DICDI  Uncharacterized protein OS=Dictyostel


Domain annotation for each sequence (and alignments):
>> tr|Q54PG3|Q54PG3_DICDI  tRNA (guanine(26)-N(2))-dimethyltransferase OS=Dictyostelium discoideum OX=44689 GN=DDB018607
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  417.4   0.2  1.3e-128  4.1e-125       8     376 .]      57     455 ..      44     455 .. 0.91

  Alignments for each domain:
  == domain 1  score: 417.4 bits;  conditional E-value: 1.3e-128
                             ----SS--TT--SS--GGGHHHHHHHHHH....HHHHHHHH-S-......EEEEESS-TTSHHHHHHHHH-.S-EEEEEEE-S-HHH CS
                     TRM   8 edkevtvskkeeVFYNPvqefnRDlsvlvir.qlellkkklgek......ikvldaLsasGlRaiRfalEv.pgvkevlaNDisekA 86 
                             + +++  ++++eVFYNPvqefnRD+s+l+i+ ++e +kk++ e+      i+vl+aL+a+GlR+iR+a+E+ +    +laNDi++ A
  tr|Q54PG3|Q54PG3_DICDI  57 NSATILYNNQNEVFYNPVQEFNRDMSILMIKlFIEERKKECLERgkpfkkIRVLEALAATGLRSIRYAKEIgDDLDYILANDILQTA 143
                             3334558899*********************9999999999887889999********************9446789********** PP

                             HHHHHHHHHHTT--G.GEEEE-S-HHHHHC...--SS-EEEEEE--SS--GGGHHHHHHHEEEEEEEEEEE--HHHHTTSSHHHHHH CS
                     TRM  87 velikeNvklnevee.ivvineddAnvlla...ekkkrfdviDlDPfGspapfldsavqsvkekglLlvTaTDtavLaGaspekclr 169
                             v++i +N ++n v e ++++n +dA+++++   +++k++dv+D+DP+G+p++fldsavq+v+++glL+vTaTDtavL+G++pe+c++
  tr|Q54PG3|Q54PG3_DICDI 144 VDSIVKNREYNGVPEeRIKPNLGDATMVMMenrTHSKQYDVVDVDPYGAPTQFLDSAVQAVADGGLLCVTATDTAVLCGSYPEACFH 230
                             *************955**************8878899************************************************** PP

                             HHSSB--.-STTHHHHHHHHHHHHHHHHHHTTTEEEEEEEEEEETTEEEEEEEEEE-HHHHHHHHTTEEEEEEETTT.......... CS
                     TRM 170 kYgaval.kselcHEvalRillkavareaakYekavepllslsadfYvrvfvkvktgaakvkkvleklglvlhCsgC.......... 245
                             kY++v++ +  +cHE++lRill++++++a++Y++ ++p+lsls+dfYvrvfv+v +++ ++kk l+k++ ++ C+gC          
  tr|Q54PG3|Q54PG3_DICDI 231 KYQSVPVhRAGFCHEMGLRILLHSIEQHANRYKRHIVPILSLSVDFYVRVFVRVYSSPLEAKKALSKMANIFSCIGCgsfhiqptgv 317
                             ******934679*****************************************************************9888777664 PP

                             .......--EEEE--GGG--.........SB-TTT-SBEEEEEEEE-S-S--HHHHHHHHHHHCT..-TTS..-HHHHHHHHHHHHH CS
                     TRM 246 .......lseekvkglakfk.........aecehcgaklhlaGPlwlgplkdkefveevleeaekekeeel..kkrvkklLklikeE 314
                                    +         k+k          +c+hc +++++aGP+w+  +++ +f ++ +  +ek+  +++  ++r+ ++L+ + +E
  tr|Q54PG3|Q54PG3_DICDI 318 vkeegnsI---------KYKvpllnkevgSHCQHCTKQYQFAGPFWAKRIHNVDFCKQAISFLEKNP-TTFntSRRMYGVLTSVIDE 394
                             32222221.........223567777778************************************76.33336************** PP

                             HS--SS-EEHHHHHHHHT-SS---HHHHHHH....TT-EE-TTSTTEEE-SS-HHHHHHHHH CS
                     TRM 315 lldaplyydlsqlasvlklsvpplkkvvsalkelgfevsrtHakpkaikTnapleavvevlr 376
                             l+d+ +y++ ++ +++l+ls+pp+  + sa+++ g++vs +H+ p +ikT+ap++++++++r
  tr|Q54PG3|Q54PG3_DICDI 395 LPDQMFYFKSDHFTHTLHLSTPPTAMIKSAILNGGYKVSSSHVLP-SIKTDAPFQFLWDIFR 455
                             *******************************************99.6************986 PP

>> sp|Q54WD6|TRM5_DICDI  tRNA (guanine(37)-N1)-methyltransferase OS=Dictyostelium discoideum OX=44689 GN=trmt5 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.1     2e-09   6.4e-06      52     137 ..     216     302 ..     178     305 .. 0.81

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 2e-09
                           EEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC...--SS-EEEEEE--SS--GGGHH CS
                   TRM  52 kvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvineddAnvlla...ekkkrfdviDlDPfGspapfld 137
                            + d +++ G  a+  a+   ++ +v+aND+++  v+ +keN+k n  e  v+i++ dA+ +++   ek+  f ++ +    ++ +fld
  sp|Q54WD6|TRM5_DICDI 216 IICDMFAGVGPFALPAAKI--KKCKVYANDLNPSSVKYMKENAKTNRLESKVEISNLDARDFVKslvEKSIPFTHVVMNLPSTSIEFLD 302
                           5677777777777777765..6779***********************************99987777777788877776666777766 PP

>> sp|Q86JB0|Y8324_DICDI  Putative uncharacterized protein DDB_G0277003 OS=Dictyostelium discoideum OX=44689 GN=DDB_G027
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.3   8.5e-06     0.027      51     115 ..     169     234 ..      60     246 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 8.5e-06
                            EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--..GGEEEE-S-HHHHHC CS
                    TRM  51 ikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneve..eivvineddAnvlla 115
                             ++l+  s++Gl +i     ++  k+v++ D s+k ++ +k N++ln+ e  + ++ + dd n  ++
  sp|Q86JB0|Y8324_DICDI 169 KNILELGSGTGLVGIILD-FIKPLKKVILTDYSPKVLKNLKFNMELNNLEiqDFINDDDDDNNNNVN 234
                            5899999*******9655.4699************************99876777777777665554 PP

>> tr|Q54PP5|Q54PP5_DICDI  Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB_G0284401 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   3.2e-05       0.1      48     111 ..      49     110 ..      23     126 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 3.2e-05
                             -S-EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HH CS
                     TRM  48 gekikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvineddAn 111
                             ++++++ld  +++G  ++ +  Ev + ++ +  D+s+k +e++ + vk n++++ ++++ +d +
  tr|Q54PP5|Q54PP5_DICDI  49 EKPMTILDVAAGTGPLSL-YGAEVYKNSKFITTDFSPKMIEIVDRLVKDNNIKN-IETHVMDGQ 110
                             45799*********9999.8999999999999*********************9.777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (376 nodes)
Target sequences:                        12739  (6856946 residues searched)
Passed MSV filter:                       958  (0.0752021); expected 254.8 (0.02)
Passed bias filter:                      233  (0.0182903); expected 254.8 (0.02)
Passed Vit filter:                        16  (0.00125599); expected 12.7 (0.001)
Passed Fwd filter:                         4  (0.000313996); expected 0.1 (1e-05)
Initial search space (Z):              12739  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.17u 0.01s 00:00:00.18 Elapsed: 00:00:00.06
# Mc/sec: 42970.19
//
[ok]