# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TRM.hmm.txt
# target sequence database:        proteomes/Monosiga_brevicollis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TRM  [M=376]
Accession:   PF02005.15
Description: N2,N2-dimethylguanosine tRNA methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
   9.8e-117  389.3   0.0   1.2e-116  389.1   0.0    1.0  1  tr|A9VDF1|A9VDF1_MONBE  tRNA (guanine(26)-N(2))-dimethyltrans
    0.00021   19.6   0.0    0.00032   19.0   0.0    1.3  1  tr|A9UWK9|A9UWK9_MONBE  Predicted protein (Fragment) OS=Monos
     0.0081   14.4   0.0      0.012   13.9   0.0    1.2  1  tr|A9V7D5|A9V7D5_MONBE  Predicted protein OS=Monosiga brevico
  ------ inclusion threshold ------
      0.042   12.1   0.0      0.052   11.7   0.0    1.1  1  tr|A9UR20|A9UR20_MONBE  Uncharacterized protein (Fragment) OS


Domain annotation for each sequence (and alignments):
>> tr|A9VDF1|A9VDF1_MONBE  tRNA (guanine(26)-N(2))-dimethyltransferase OS=Monosiga brevicollis OX=81824 GN=34698 PE=3 SV
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  389.1   0.0  5.1e-120  1.2e-116       6     376 .]      14     458 ..       9     458 .. 0.92

  Alignments for each domain:
  == domain 1  score: 389.1 bits;  conditional E-value: 5.1e-120
                             EE----SS--TT--SS--GGGHHHHHHHHHH....HHHHHHHH-S-......................................... CS
                     TRM   6 kvedkevtvskkeeVFYNPvqefnRDlsvlvir.qlellkkklgek......................................... 50 
                              + ++++ ++++e VFYNPvqefnRDls  vi  + + +   ++ +                                         
  tr|A9VDF1|A9VDF1_MONBE  14 VEGKAAILFPEDEGVFYNPVQEFNRDLSTCVILnFANRFMPDTSDPwgkkharrtshalgdplfegshrkeaeeqikaqspavestp 100
                             34444588********************9998546666666655557777************************************* PP

                             .....................EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--G.GEEEE-S-HHHHHC CS
                     TRM  51 .....................ikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklnevee.ivvineddAnvlla 115
                                                  i++l+aL+asGlR+iR+  E+p  ++++ ND+s+ Ave i++N  +n+++e  + +n +dAnv+++
  tr|A9VDF1|A9VDF1_MONBE 101 apgertmynpsdasfdretqgIRILEALAASGLRSIRYYREIPAIRSIVCNDFSQAAVENIRRNLAYNDIAEsGIIPNFGDANVVMH 187
                             ***********************************************************************8789************ PP

                             ....--SS-EEEEEE--SS--GGGHHHHHHHEEEEEEEEEEE--HHHHTTSSHHHHHHHHSSB---STTHHHHHHHHHHHHHHHHHH CS
                     TRM 116 ....ekkkrfdviDlDPfGspapfldsavqsvkekglLlvTaTDtavLaGaspekclrkYgavalkselcHEvalRillkavareaa 198
                                 +   rfdv+DlDP+G+++pfld+av+s+++         D+avLaGa+p++c++kYg+v+lk  +cHE+++Rill+++ ++aa
  tr|A9VDF1|A9VDF1_MONBE 188 dastRPGARFDVVDLDPYGTASPFLDAAVKSITD--------GDMAVLAGAHPDACYAKYGSVSLKGPFCHESGVRILLNSISTAAA 266
                             887667789*********************9877........7******************************************** PP

                             TTTEEEEEEEEEEETTEEEEEEEEEE-HHHHHHHHTTEEEEEEETTT..........--EEEE--GGG--........SB-TTT-SB CS
                     TRM 199 kYekavepllslsadfYvrvfvkvktgaakvkkvleklglvlhCsgC..........lseekvkglakfk........aecehcgak 267
                             +Y  +++pl+s s+dfY rvfv+v +g+ak+k ++++ g+v+ C +C                 + +kf+         +c+hcg  
  tr|A9VDF1|A9VDF1_MONBE 267 RYGSYIQPLMSCSIDFYCRVFVRVFKGPAKAKLSAQHNGVVYMCPRChsfasasfgrF-----GDKNKFRhghapsvgDHCQHCGGP 348
                             ***********************************************87766444330.....3333333555677779******** PP

                             EEEEEEEE-S-S--HHHHHHHHHHHCT..-TTS..-HHHHHHHHHHHHHHS--SS-EEHHHHHHHHT-SS---HHHHHHH....TT- CS
                     TRM 268 lhlaGPlwlgplkdkefveevleeaekekeeel..kkrvkklLklikeElldaplyydlsqlasvlklsvpplkkvvsalkelgfev 352
                             ++++GPlwlgp++d +fv++ ++ +++ +++ +  + r++++ +++keEl+dap+ y++s+la++ ++++ p ++++sal ++g++v
  tr|A9VDF1|A9VDF1_MONBE 349 FQIGGPLWLGPMHDPDFVGQCADYLKA-HRDDFgtADRMEGMFAICKEELPDAPFHYNVSDLAHTAHCQSIPHDTFRSALVNAGYRV 434
                             **************************9.55555579*************************************************** PP

                             EE-TTSTTEEE-SS-HHHHHHHHH CS
                     TRM 353 srtHakpkaikTnapleavvevlr 376
                             s tH++p+++kT+ap  ++++ lr
  tr|A9VDF1|A9VDF1_MONBE 435 SPTHTNPQGMKTDAPSTFIWDLLR 458
                             *********************986 PP

>> tr|A9UWK9|A9UWK9_MONBE  Predicted protein (Fragment) OS=Monosiga brevicollis OX=81824 GN=1458 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   0.0   1.4e-07   0.00032      69     114 ..     143     185 ..      98     195 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 1.4e-07
                             HH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHH CS
                     TRM  69 lEvpgvkevlaNDisekAvelikeNvklneveeivvineddAnvll 114
                             +   + ++v+aND++++ ++ + +Nv ln v++ v++ ++d  +++
  tr|A9UWK9|A9UWK9_MONBE 143 K---NGRRVYANDLNPESYAALTQNVVLNRVHNHVQTYNMDGGAVV 185
                             3...4789*************************9*99999987776 PP

>> tr|A9V7D5|A9V7D5_MONBE  Predicted protein OS=Monosiga brevicollis OX=81824 GN=28161 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.0   5.2e-06     0.012      53     111 ..     240     297 ..     201     303 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 5.2e-06
                             EEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HH CS
                     TRM  53 vldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvineddAn 111
                             v+d +++ G  ++ +++  + ++   a + +++Ave +++N kln+v+++ +++e+d +
  tr|A9V7D5|A9V7D5_MONBE 240 VVDLFAGIGYFTLPYLVH-ARARFLHACEWNPHAVEALRRNLKLNQVADRCEVHEGDNR 297
                             677788888888888888.8889999999**************************9976 PP

>> tr|A9UR20|A9UR20_MONBE  Uncharacterized protein (Fragment) OS=Monosiga brevicollis OX=81824 GN=2498 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   2.3e-05     0.052      52     116 ..      46     110 ..      24     133 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 2.3e-05
                             EEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC...- CS
                     TRM  52 kvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvineddAnvlla...e 116
                              v+da+ + G  ai  al      +vla D+ +  +e  ++N+++  ve+ + + ++dA  +l+   +
  tr|A9UR20|A9UR20_MONBE  46 MVIDAFCGPGANAIQMALA---GCQVLAIDLDPVKLEAARHNASIYGVEDQIDFVHGDAVSVLRqlaS 110
                             589**************98...6689999*************************9*******995541 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (376 nodes)
Target sequences:                         9188  (5511963 residues searched)
Passed MSV filter:                       229  (0.0249238); expected 183.8 (0.02)
Passed bias filter:                      181  (0.0196996); expected 183.8 (0.02)
Passed Vit filter:                        12  (0.00130605); expected 9.2 (0.001)
Passed Fwd filter:                         4  (0.00043535); expected 0.1 (1e-05)
Initial search space (Z):               9188  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.15u 0.01s 00:00:00.16 Elapsed: 00:00:00.07
# Mc/sec: 29607.12
//
[ok]