# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TRM.hmm.txt
# target sequence database:        proteomes/Natronomonas_moolapensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TRM  [M=376]
Accession:   PF02005.15
Description: N2,N2-dimethylguanosine tRNA methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.7e-86  288.1   0.0    1.9e-86  287.9   0.0    1.0  1  tr|M1XK62|M1XK62_NATM8  tRNA (guanine(26)-N(2))-dimethyltrans
  ------ inclusion threshold ------
      0.011   12.3   0.0      0.016   11.7   0.0    1.2  1  tr|M1Y3X8|M1Y3X8_NATM8  tRNA (Guanine(37)-N(1))-methyltransfe


Domain annotation for each sequence (and alignments):
>> tr|M1XK62|M1XK62_NATM8  tRNA (guanine(26)-N(2))-dimethyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / J
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  287.9   0.0   1.4e-89   1.9e-86       1     373 [.       6     363 ..       6     366 .] 0.90

  Alignments for each domain:
  == domain 1  score: 287.9 bits;  conditional E-value: 1.4e-89
                             TTEEEEE----SS..--TT--SS--GGGHHHHHHHHHH...HHHHHHHH-S-EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HH CS
                     TRM   1 Geakikvedkevt..vskkeeVFYNPvqefnRDlsvlvirqlellkkklgekikvldaLsasGlRaiRfalEvpgvkevlaNDisek 85 
                             G+++i+v+++       + + VFYNPvqe nRD++ +v+r ++  +       ++lda++asG+Ra+R a       ++   Di e 
  tr|M1XK62|M1XK62_NATM8   6 GAVTIEVPEERHGasEGSGSGVFYNPVQELNRDVTAAVLRVVDDECD------SYLDAMTASGVRAVRAAEA---GYAATGCDIDEA 83 
                             566777777653322456688*****************665554444......48*************8855...4556678***** PP

                             HHHHHHHHHHHTT--GGEEEE-S-HHHHHC--SS-EEEEEE--SS--GGGHHHHHHHEEEEEEEEEEE--HHHHTTSSHHHHHHHHS CS
                     TRM  86 AvelikeNvklneveeivvineddAnvllaekkkrfdviDlDPfGspapfldsavqsvkekglLlvTaTDtavLaGaspekclrkYg 172
                             Av+l + N + n  +   +i++ + n+ +  +++ +dv+DlDPfG+p pf d+a +s++e  +++vTaTDta+L+Ga+ e+++r Yg
  tr|M1XK62|M1XK62_NATM8  84 AVDLARSNLERNGLSG--TIHHRNVNAHM--HEHGHDVVDLDPFGTPIPFADAAFRSARE--YVCVTATDTAPLCGAHFESGVRSYG 164
                             ***************9..55555677778..67789**********************99..************************* PP

                             SB---STTHHHHHHHHHHHHHHHHHHTTTEEEEEEEEEEETTEEEEEEEEEE-HHHHHHHHTTEEEEEEETTT--E.EEE--GGG-- CS
                     TRM 173 avalkselcHEvalRillkavareaakYekavepllslsadfYvrvfvkvktgaakvkkvleklglvlhCsgClse.ekvkglakfk 258
                             av+ ++e+  E++lR+ll+a++r+aa+Y+ a +p+ls+++ +Yvr +++++ ga+ +++++ +lg+v hC +Cl + ++ + +a   
  tr|M1XK62|M1XK62_NATM8 165 AVPRNTEFHPEMGLRVLLSALVRTAARYDLAATPVLSHVSSHYVRTYLRLDGGARAADELFGELGYVDHCQRCLWRaHERTLVADPT 251
                             *************************************************************************77624444455566 PP

                             SB-TTT-SBEEEEEEEE-S-S--HHHHHHHHHHHCT..-TTS-HHHHHHHHHHHHHHS--SS-EEHHHHHHHHT-SS---HHHHHHH CS
                     TRM 259 aecehcgaklhlaGPlwlgplkdkefveevleeaekekeeelkkrvkklLklikeElldaplyydlsqlasvlklsvpplkkvvsal 345
                             a c++cg+++  aGP+wlgp +d +fve+v e++ +  +  ++   + lL ++  E l+ p+ yd ++l ++       ++++  al
  tr|M1XK62|M1XK62_NATM8 252 AACPECGQSTWTAGPIWLGPAHDVAFVERVGEAVPE--SFGTASAARDLLGTVAGE-LHRPTHYDQHRLYKRWGEPNTAMDEFLGAL 335
                             9*********************************99..4566888999********.9***************************** PP

                             ....TT-EE-TTSTTEEE-SS-HHHHHH CS
                     TRM 346 kelgfevsrtHakpkaikTnapleavve 373
                             +e+g+e+srtH+ ++++kT+a + ++ e
  tr|M1XK62|M1XK62_NATM8 336 REAGHEASRTHYGGTTFKTDAGVAEIRE 363
                             **********************999876 PP

>> tr|M1Y3X8|M1Y3X8_NATM8  tRNA (Guanine(37)-N(1))-methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JCM
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   1.2e-05     0.016      79     149 ..     204     273 ..     180     275 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 1.2e-05
                             EE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC--SS-EEEEEE--SS--GGGHHHHHHHEEEEEEE CS
                     TRM  79 aNDisekAvelikeNvklneveeivvineddAnvllaekkkrfdviDlDPfGspapfldsavqsvkekglL 149
                               D++e Ave +++N++ n v+++v + ++d + +    +   d i +    s+  fld+av+ + e+ lL
  tr|M1Y3X8|M1Y3X8_NATM8 204 GVDLNEAAVEYLRRNAERNGVSDRVIAINADVRDVT-GYDDWADRIVMNLPHSADGFLDTAVELAGEDCLL 273
                             569********************8877777888776.5555556666665567888888888777777666 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (376 nodes)
Target sequences:                         2723  (809592 residues searched)
Passed MSV filter:                        70  (0.0257069); expected 54.5 (0.02)
Passed bias filter:                       67  (0.0246052); expected 54.5 (0.02)
Passed Vit filter:                         7  (0.00257069); expected 2.7 (0.001)
Passed Fwd filter:                         2  (0.000734484); expected 0.0 (1e-05)
Initial search space (Z):               2723  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.02
# Mc/sec: 15220.33
//
[ok]