# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/TRM.hmm.txt
# target sequence database: proteomes/Ornithorhynchus_anatinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: TRM [M=376]
Accession: PF02005.15
Description: N2,N2-dimethylguanosine tRNA methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
3.7e-67 227.4 3.5 2.6e-56 191.7 0.6 3.1 3 tr|F6R9W8|F6R9W8_ORNAN tRNA (guanine(26)-N(2))-dimethyltrans
6.3e-09 35.7 0.0 7.1e-09 35.6 0.0 1.0 1 tr|K7EB46|K7EB46_ORNAN Uncharacterized protein OS=Ornithorhy
------ inclusion threshold ------
0.066 12.6 0.0 0.1 12.0 0.0 1.2 1 tr|F6ZRD9|F6ZRD9_ORNAN tRNA methyltransferase 12 homolog OS=
Domain annotation for each sequence (and alignments):
>> tr|F6R9W8|F6R9W8_ORNAN tRNA (guanine(26)-N(2))-dimethyltransferase OS=Ornithorhynchus anatinus OX=9258 GN=TRMT1L PE=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -0.7 0.0 0.1 7.6e+02 228 246 .. 95 122 .. 88 154 .. 0.69
2 ! 191.7 0.6 3.5e-60 2.6e-56 14 311 .. 167 489 .. 147 514 .. 0.85
3 ! 34.5 0.0 2.1e-12 1.5e-08 312 374 .. 549 608 .. 525 610 .. 0.83
Alignments for each domain:
== domain 1 score: -0.7 bits; conditional E-value: 0.1
HHHHHHTTEEEEEEETTT.........- CS
TRM 228 kvkkvleklglvlhCsgC.........l 246
++++ +k+g +hC+ C +
tr|F6R9W8|F6R9W8_ORNAN 95 IGDQTSTKMGAHYHCIICsatitrrtdM 122
578999************6654333220 PP
== domain 2 score: 191.7 bits; conditional E-value: 3.5e-60
--TT--SS--GGGHHHHHHHHHH...HHHHHHHH-S-EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT-- CS
TRM 14 vskkeeVFYNPvqefnRDlsvlvirqlellkkklgekikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneve 100
++k++ ++NP ++ nR l + l++l ++ ++++ lda+ a+G+ ++ +a+ + + +v +ND++e+ v +i+eN +ln+++
tr|F6R9W8|F6R9W8_ORNAN 167 TPQKTDSYFNPKMKLNRQLIFCA---LAVLAEE-RSPLECLDAFGATGIMGLQWAKHLGNSVKVTINDLNENSVMMIQENCHLNKMK 249
6788899************9999...7777777.689*******************************************9999988 PP
.....................GGEEEE-S-HHHHHC--SS-EEEEEE--SS--GGGHHHHHHHEEEEEEEEEEE--HHHHTTSSHHH CS
TRM 101 .....................eivvineddAnvllaekkkrfdviDlDPfGspapfldsavqsvkekglLlvTaTDtavLaGaspek 166
++++ ++dAnvl+ + + fd+i lDPfG+++++lds + v++ g+++vT+TD ++L ++ +
tr|F6R9W8|F6R9W8_ORNAN 250 vvlgnkeedegnedleveenvGTIEVTKMDANVLM--HLRSFDFIHLDPFGTSVNYLDSTFRNVRNLGIVSVTSTDISSLYAKTLHV 334
88999999999999999875558999*********..7899********************************************** PP
HHHHHSSB---STTHHHHHHHHHHHHHHHHHHTTTEEEEEEEEEEETTEEEEEEEEEE-HHHHHHHHTTEEEEEEETTT.....--E CS
TRM 167 clrkYgavalkselcHEvalRillkavareaakYekavepllslsadfYvrvfvkvktgaakvkkvleklglvlhCsgC.....lse 248
r+Yg + +++e++ E a Ri++ avar+aa+ +k +e+ll+++ +++v v v+v +g+ +++++++k+ +++hC C +e
tr|F6R9W8|F6R9W8_ORNAN 335 ARRHYGCTIVRTEYYKELAARIVVAAVARAAARCNKGIEVLLAVALEHFVLVIVRVLRGPSQADETAKKIRYLIHCQWCeerifQKE 421
*******************************************************************************66654222 PP
EEE--GGG--.....SB-TTT-SBEEEEEEEE-S-S--HHHHHHHHHHHCT..-TTS-HHHHHHHHHH CS
TRM 249 ekvkglakfk.....aecehcgaklhlaGPlwlgplkdkefveevleeaekekeeelkkrvkklLkli 311
+++ + + ++ + + g++ GPlw g l +++f+ ++l +a k+ e ++ +k l+ +
tr|F6R9W8|F6R9W8_ORNAN 422 GNMVEENPYRqlpcdCHGSMPGKTAIELGPLWSGSLFNTAFLWRMLCKAVKHGLEDIQTLIKTLICEA 489
3333333333544223444556666778******************9999966666666666665444 PP
== domain 3 score: 34.5 bits; conditional E-value: 2.1e-12
HHHHS--SS-EEHHHHHHHHT-SS---HHHHHHH....TT-EE-TTSTTEEE-SS-HHHHHHH CS
TRM 312 keElldaplyydlsqlasvlklsvpplkkvvsalkelgfevsrtHakpkaikTnapleavvev 374
++E + p+yy++++ s+ +++p+l+k+ + l ++gf+vsrtH+ p +++Tnapl ++ +
tr|F6R9W8|F6R9W8_ORNAN 549 SAE--HPPFYYNIHR-HSIKGMNMPKLNKFLQYLTQAGFRVSRTHFDPMGVRTNAPLIQFKSI 608
334..6789999988.56789***********************************9777665 PP
>> tr|K7EB46|K7EB46_ORNAN Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 35.6 0.0 9.9e-13 7.1e-09 2 41 .. 56 96 .. 54 110 .. 0.71
Alignments for each domain:
== domain 1 score: 35.6 bits; conditional E-value: 9.9e-13
TEEEEE----.SS--TT--SS--GGGHHHHHHHHHH....HH CS
TRM 2 eakikvedke.vtvskkeeVFYNPvqefnRDlsvlvir.qle 41
ea + +e+++ ++++ ++eVFYNPvqefnRDl+++v+ +
tr|K7EB46|K7EB46_ORNAN 56 EAVV-TEGAArIVFPGANEVFYNPVQEFNRDLTCAVVTeFAR 96
4444.44444499***********************853332 PP
>> tr|F6ZRD9|F6ZRD9_ORNAN tRNA methyltransferase 12 homolog OS=Ornithorhynchus anatinus OX=9258 GN=TRMT12 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.0 0.0 1.4e-05 0.1 61 111 .. 234 283 .. 210 294 .. 0.85
Alignments for each domain:
== domain 1 score: 12.0 bits; conditional E-value: 1.4e-05
SHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HH CS
TRM 61 GlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvineddAn 111
G ++ f++ +gv v a + +++Av+ +++N +ln v+++ +i+ +d +
tr|F6ZRD9|F6ZRD9_ORNAN 234 GYFTLPFLVH-AGVAFVHACEWNPHAVAALRRNLELNGVADRCQIHAGDNR 283
5555666666.789999*****************************99976 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (376 nodes)
Target sequences: 21677 (8259262 residues searched)
Passed MSV filter: 620 (0.0286017); expected 433.5 (0.02)
Passed bias filter: 473 (0.0218204); expected 433.5 (0.02)
Passed Vit filter: 32 (0.00147622); expected 21.7 (0.001)
Passed Fwd filter: 3 (0.000138396); expected 0.2 (1e-05)
Initial search space (Z): 21677 [actual number of targets]
Domain search space (domZ): 3 [number of targets reported over threshold]
# CPU time: 0.25u 0.01s 00:00:00.26 Elapsed: 00:00:00.08
# Mc/sec: 38818.53
//
[ok]