# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/TRM.hmm.txt
# target sequence database:        proteomes/Trichoplax_adhaerens.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       TRM  [M=376]
Accession:   PF02005.15
Description: N2,N2-dimethylguanosine tRNA methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
   1.2e-110  369.6   6.3    4.1e-95  318.5   4.3    2.0  2  tr|B3RPX0|B3RPX0_TRIAD  tRNA (guanine(26)-N(2))-dimethyltrans
  ------ inclusion threshold ------
      0.011   14.4   0.1      0.048   12.2   0.0    2.0  2  tr|B3S2Q2|B3S2Q2_TRIAD  Uncharacterized protein OS=Trichoplax


Domain annotation for each sequence (and alignments):
>> tr|B3RPX0|B3RPX0_TRIAD  tRNA (guanine(26)-N(2))-dimethyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_53
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  318.5   4.3   7.1e-99   4.1e-95       8     268 ..       6     301 ..       1     304 [. 0.92
   2 !   52.3   0.0   5.5e-18   3.2e-14     313     376 .]     302     365 ..     299     365 .. 0.97

  Alignments for each domain:
  == domain 1  score: 318.5 bits;  conditional E-value: 7.1e-99
                             ----SS--TT--SS--GGGHHHHHHHHHH....HHHHHHHH-S-..............EEEEESS-TTSHHHHHHHHH-S-EEEEEE CS
                     TRM   8 edkevtvskkeeVFYNPvqefnRDlsvlvir.qlellkkklgek..............ikvldaLsasGlRaiRfalEvpgvkevla 79 
                             e+++++++++++ FYNP+q fnRD+s++vi+ ++++ +k+++++              ++++++Lsa+GlR+iR+alE+p+ k+v+a
  tr|B3RPX0|B3RPX0_TRIAD   6 EGQAKILNDDQDAFYNPIQTFNRDISIAVIKqFIKTCQKEVSTQckvrrnlsaavekgFTIFEGLSATGLRSIRYALELPKIKAVIA 92 
                             444588999*********************978888888887779****************************************** PP

                             E-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC....--SS-EEEEEE--SS--GGGHHHHHHHEEEEEEEEEEE--HHHHTTS CS
                     TRM  80 NDisekAvelikeNvklneveeivvineddAnvlla....ekkkrfdviDlDPfGspapfldsavqsvkekglLlvTaTDtavLaGa 162
                             ND ++   ++i++N+++n++ ++v+++ +dA+++++    + + +f+v+D+DP+Gspa fld+avqsv+++glL++T+TD+avL+G+
  tr|B3RPX0|B3RPX0_TRIAD  93 NDNNPSSFKCIERNIEYNKIGHVVQPHFGDARMMMYdnsnSLDDQFQVVDIDPYGSPAIFLDAAVQSVSDGGLLCITCTDMAVLCGN 179
                             ************************************887777889****************************************** PP

                             SHHHHHHHHSSB---STTHHHHHHHHHHHHHHHHHHTTTEEEEEEEEEEETTEEEEEEEEEE-HHHHHHHHTTEEEEEEETTT.... CS
                     TRM 163 spekclrkYgavalkselcHEvalRillkavareaakYekavepllslsadfYvrvfvkvktgaakvkkvleklglvlhCsgC.... 245
                             +  +c++kYg+v+l+s+ cHE+alRi l++++++a++Y ++++plls+s+d+Y+rvfv+v  g+++v+++++k  +v++C++C    
  tr|B3RPX0|B3RPX0_TRIAD 180 HAGSCFAKYGSVSLRSKHCHEMALRIALSSIESNANRYGRYIVPLLSVSVDYYIRVFVRVFYGKTEVNRSASKKSFVFQCTSCdsfy 266
                             *************************************************************************************** PP

                             .......--EEEE--GGG--.....SB-TTT-SBE CS
                     TRM 246 .......lseekvkglakfk.....aecehcgakl 268
                                    ++++++++++  k     ++c++c +kl
  tr|B3RPX0|B3RPX0_TRIAD 267 lqplgskADTGNNQNFQPAKfnmenQKCTECDSKL 301
                             99988773334444444444557779999998876 PP

  == domain 2  score: 52.3 bits;  conditional E-value: 5.5e-18
                             HHHS--SS-EEHHHHHHHHT-SS---HHHHHHH....TT-EE-TTSTTEEE-SS-HHHHHHHHH CS
                     TRM 313 eElldaplyydlsqlasvlklsvpplkkvvsalkelgfevsrtHakpkaikTnapleavvevlr 376
                             +E +d+plyy+++ la+ +++   p  k++sal++lg++vs tHa+++a+kT+a+ ++v++v+r
  tr|B3RPX0|B3RPX0_TRIAD 302 KEIPDQPLYYVTDSLANSIHSVCIPFLKIRSALLQLGYKVSSTHAHKSAFKTDASNSVVWDVMR 365
                             6889***********************************************************7 PP

>> tr|B3S2Q2|B3S2Q2_TRIAD  Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_58107 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.5      0.13   7.3e+02     245     327 ..     124     205 ..     118     218 .. 0.70
   2 ?   12.2   0.0   8.3e-06     0.048      44     109 ..     549     618 ..     512     647 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.13
                             T--EEEE--GGG--SB-TTT-SBEEEEE.EEE-S-S--HHHHHHHHHHHCT..-TTS-HHHHHHHHHHHHHHS--SS-EEHHHH CS
                     TRM 245 ClseekvkglakfkaecehcgaklhlaG.PlwlgplkdkefveevleeaekekeeelkkrvkklLklikeElldaplyydlsql 327
                             C+s++++ +l+++++e e + + ++ +G P   g  k++   e  +++ ++ k+++ kk+++++ + ++e+  da l+ d ++l
  tr|B3S2Q2|B3S2Q2_TRIAD 124 CTSSQSEDNLNTVQNEDESLMQLMQTMGlPTAFGSNKQNSNYEDQARKSHSGKKKKGKKKINRMKEEANED--DANLMTDNHHL 205
                             77777777777777777777777777776777777666666666666667767777788888888887777..66666565555 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 8.3e-06
                             HHHH-S-.......EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S- CS
                     TRM  44 kkklgek.......ikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvinedd 109
                              +k++++         ++da+ + G   i fa+      +v+a Di ++ +++ ++N+k+ +ve+ +++  +d
  tr|B3S2Q2|B3S2Q2_TRIAD 549 PEKIAQHiaercrcSIIIDAFCGVGGNCIQFAKT---CDHVIAIDIDPNKIKCARHNAKIYNVEHKIEFIVGD 618
                             444444444455545699**************98...6789999********************988766554 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (376 nodes)
Target sequences:                        11518  (5222075 residues searched)
Passed MSV filter:                       459  (0.0398507); expected 230.4 (0.02)
Passed bias filter:                      267  (0.0231811); expected 230.4 (0.02)
Passed Vit filter:                        18  (0.00156277); expected 11.5 (0.001)
Passed Fwd filter:                         2  (0.000173641); expected 0.1 (1e-05)
Initial search space (Z):              11518  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.15u 0.00s 00:00:00.15 Elapsed: 00:00:00.05
# Mc/sec: 39270.00
//
[ok]