# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/TRM.hmm.txt
# target sequence database: proteomes/Xenopus_tropicalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: TRM [M=376]
Accession: PF02005.15
Description: N2,N2-dimethylguanosine tRNA methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.9e-143 478.6 0.0 2.3e-143 478.4 0.0 1.0 1 tr|F6XJY2|F6XJY2_XENTR tRNA (guanine(26)-N(2))-dimethyltrans
1.3e-54 186.2 0.5 1.3e-54 186.2 0.5 1.7 2 tr|F7CJB7|F7CJB7_XENTR tRNA (guanine(26)-N(2))-dimethyltrans
0.0028 17.3 0.0 0.0048 16.6 0.0 1.4 1 sp|F6VSS6|TRM5_XENTR tRNA (guanine(37)-N1)-methyltransfera
------ inclusion threshold ------
0.051 13.2 0.0 0.082 12.5 0.0 1.3 1 tr|F7AMM4|F7AMM4_XENTR tRNA methyltransferase 12 homolog OS=
0.054 13.1 0.0 0.067 12.8 0.0 1.2 1 tr|F6ZI67|F6ZI67_XENTR EEF1A lysine methyltransferase 2 OS=X
Domain annotation for each sequence (and alignments):
>> tr|F6XJY2|F6XJY2_XENTR tRNA (guanine(26)-N(2))-dimethyltransferase OS=Xenopus tropicalis OX=8364 GN=trmt1 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 478.4 0.0 4.7e-147 2.3e-143 3 376 .] 43 486 .. 41 486 .. 0.93
Alignments for each domain:
== domain 1 score: 478.4 bits; conditional E-value: 4.7e-147
EEEEE----SS--TT--SS--GGGHHHHHHHHHH....HHHHHHHH-S-...................................... CS
TRM 3 akikvedkevtvskkeeVFYNPvqefnRDlsvlvir.qlellkkklgek...................................... 50
+ i++ +++v+++++++VFYNPvqefnRDl+++vi ++ l ++ g++
tr|F6XJY2|F6XJY2_XENTR 43 TFIHEGKASVIFPSANQVFYNPVQEFNRDLTCAVITeFSRLHLQQKGTDivvpgerveqklvvnlsetgedkvtsspennstppdrp 129
55555666699************************856666555555559999********************************** PP
...........EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC...--SS-EEE CS
TRM 51 ...........ikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvineddAnvlla...ekkkrfdv 123
+++l++L+asGlR+iRfa Evpg ++v+aND+s Avelik+N++ n+v ++v+ + +dA+++++ k rfdv
tr|F6XJY2|F6XJY2_XENTR 130 tahvgepcpdgLRILEGLAASGLRSIRFAREVPGLHSVVANDFSASAVELIKRNIQHNDVGNLVTGSYGDARMVMYnrtGAKDRFDV 216
****************************************************************************8887899**** PP
EEE--SS--GGGHHHHHHHEEEEEEEEEEE--HHHHTTSSHHHHHHHHSSB---STTHHHHHHHHHHHHHHHHHHTTTEEEEEEEEE CS
TRM 124 iDlDPfGspapfldsavqsvkekglLlvTaTDtavLaGaspekclrkYgavalkselcHEvalRillkavareaakYekavepllsl 210
iDlDP+Gsp+ fld+avqsv+e+glL++T+TD+avLaG+ e+c++kYga+++ks++cHE+alRill++++ +a++Y+++++pll++
tr|F6XJY2|F6XJY2_XENTR 217 IDLDPYGSPSMFLDAAVQSVSEGGLLCITCTDMAVLAGNNGETCYSKYGAMSIKSKFCHEMALRILLHSLDLRANCYQRYIVPLLCI 303
*************************************************************************************** PP
EETTEEEEEEEEEE-HHHHHHHHTTEEEEEEETTT................--EEEE--GGG--..........SB-TTT-SBEEEE CS
TRM 211 sadfYvrvfvkvktgaakvkkvleklglvlhCsgC................lseekvkglakfk..........aecehcgaklhla 271
s+dfY+rvfv+v tg+akvk ++k++l+++C+gC + k a ce+c ++++l+
tr|F6XJY2|F6XJY2_XENTR 304 SVDFYIRVFVRVFTGQAKVKMCASKQALLYNCVGCgtyhlqrlgkatthgnN--------M--KyspatgppvtASCEFCHQRHQLG 380
***********************************99887765544322211........2..13356677777************* PP
EEEE-S-S--HHHHHHHHHHHCT..-TTS..-HHHHHHHHHHHHHHS--SS-EEHHHHHHHHT-SS---HHHHHHH....TT-EE-T CS
TRM 272 GPlwlgplkdkefveevleeaekekeeel..kkrvkklLklikeElldaplyydlsqlasvlklsvpplkkvvsalkelgfevsrtH 356
GP+w++ l+dk+fve++l ++e + +++ ++r++++L++++eEl+d+plyy+l++l+sv+++++p+l +++sal+++g++vs++H
tr|F6XJY2|F6XJY2_XENTR 381 GPIWAESLHDKDFVERILSALERNP-KRFktSERIQGVLSMVTEELSDVPLYYTLDNLSSVIRCNTPSLLQFRSALLHAGYRVSLSH 466
**********************975.44446******************************************************** PP
TSTTEEE-SS-HHHHHHHHH CS
TRM 357 akpkaikTnapleavvevlr 376
a+++a+kT+ap +++++++r
tr|F6XJY2|F6XJY2_XENTR 467 ACKNALKTDAPPSVIWDIMR 486
*******************7 PP
>> tr|F7CJB7|F7CJB7_XENTR tRNA (guanine(26)-N(2))-dimethyltransferase OS=Xenopus tropicalis OX=8364 GN=trmt1l PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -4.5 2.1 2.5 1.2e+04 234 261 .. 118 147 .. 109 175 .. 0.57
2 ! 186.2 0.5 2.8e-58 1.3e-54 14 308 .. 206 524 .. 190 534 .. 0.85
Alignments for each domain:
== domain 1 score: -4.5 bits; conditional E-value: 2.5
TTEEEEEEETTT--E...EEE--GGG--SB- CS
TRM 234 eklglvlhCsgClse...ekvkglakfkaec 261
e+ + + C C+++ ++++g+ k+ c
tr|F7CJB7|F7CJB7_XENTR 118 EEYRMCICCLPCMQQkpsQNETGVPA-KTTC 147
55556666777766533333333333.2222 PP
== domain 2 score: 186.2 bits; conditional E-value: 2.8e-58
--TT--SS--GGGHHHHHHHHHH...HHHHHHHH-S-EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT-- CS
TRM 14 vskkeeVFYNPvqefnRDlsvlvirqlellkkklgekikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneve 100
++++++V +N + l + l++l k+ + ++ lda+ ++G+ ++ +a+ + + +v +NDise v++i+eN ln+ +
tr|F7CJB7|F7CJB7_XENTR 206 IPSRDQVNWNNNSKLTMQLIFCA---LAVLAKE-RNALECLDAFGSTGIMGLQWAKHLGKSVKVTINDISEGSVAMIRENCLLNNLK 288
66666666666555555555554...6777666.688*******************************************8888888 PP
....................GGEEEE-S-HHHHHC--SS-EEEEEE--SS--GGGHHHHHHHEEEEEEEEEEE--HHHHTTSSHHHH CS
TRM 101 ....................eivvineddAnvllaekkkrfdviDlDPfGspapfldsavqsvkekglLlvTaTDtavLaGaspekc 167
+ v++ + dAnvl+ + ++fd+i lDPfG+++++ld+a + v++ g+++vT+TDt +L +sp+
tr|F7CJB7|F7CJB7_XENTR 289 vltnkkddedeenevgeasdDAVEVTQLDANVLM--HLRAFDFIHLDPFGTSVNYLDAAFRNVRNLGIVSVTSTDTGSLFAKSPNVT 373
8888889999999999999779************..889************************************************ PP
HHHHSSB---STTHHHHHHHHHHHHHHHHHHTTTEEEEEEEEEEETTEEEEEEEEEE-HHHHHHHHTTEEEEEEETTT......... CS
TRM 168 lrkYgavalkselcHEvalRillkavareaakYekavepllslsadfYvrvfvkvktgaakvkkvleklglvlhCsgC......... 245
r+Yg +++e++ E a Ri+l ++ar+aa+Y+k + +lls++++++v v v+v +g+++++++++k+ ++hC C
tr|F7CJB7|F7CJB7_XENTR 374 KRHYGCHIVRTEYYRELAARIILATLARAAARYNKGIDVLLSVAVEHFVLVVVRVLRGPTQADESIHKIHSLIHCQWCeerifqkeg 460
******************************************************************************766654333 PP
.--EEEE--GGG--.....SB-TTT-SBEEEEEEEE-S-S--HHHHHHHHHHHCT..-TTS-HHHHHHH CS
TRM 246 .lseekvkglakfk.....aecehcgaklhlaGPlwlgplkdkefveevleeaekekeeelkkrvkklL 308
+ +e+ + k + + g++ + GP+w g l + f+ +++ ea +++ + ++ +k lL
tr|F7CJB7|F7CJB7_XENTR 461 nMVQENPY-----KnlpcdCQESMQGNSAVVLGPMWSGSLFNMGFLRRMMIEAVEHEMDDIHPLLKTLL 524
32223333.....3555335566677888899****************998888865555555555554 PP
>> sp|F6VSS6|TRM5_XENTR tRNA (guanine(37)-N1)-methyltransferase OS=Xenopus tropicalis OX=8364 GN=trmt5 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.6 0.0 9.9e-07 0.0048 70 115 .. 308 350 .. 246 363 .. 0.81
Alignments for each domain:
== domain 1 score: 16.6 bits; conditional E-value: 9.9e-07
H-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC CS
TRM 70 EvpgvkevlaNDisekAvelikeNvklneveeivvineddAnvlla 115
+v+aND++++ ++ + +N kln+ve++v++ ++d + +++
sp|F6VSS6|TRM5_XENTR 308 K---NCTVYANDLNPESYKWLLHNCKLNKVEKRVQAFNTDGRDFIK 350
3...5689************************9*999999998887 PP
>> tr|F7AMM4|F7AMM4_XENTR tRNA methyltransferase 12 homolog OS=Xenopus tropicalis OX=8364 GN=trmt12 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.5 0.0 1.7e-05 0.082 53 113 .. 238 297 .. 202 308 .. 0.86
Alignments for each domain:
== domain 1 score: 12.5 bits; conditional E-value: 1.7e-05
EEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHH CS
TRM 53 vldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvineddAnvl 113
v+d s+ G ++ +++ +g++ v a + +++Av +k+N +n v++ +i+e+d + l
tr|F7AMM4|F7AMM4_XENTR 238 VVDLYSGIGYFTLPYLVH-AGASFVHACEWNPHAVSALKKNLVINRVSDKCHIHEGDNRQL 297
678888899999999998.999*********************************998765 PP
>> tr|F6ZI67|F6ZI67_XENTR EEF1A lysine methyltransferase 2 OS=Xenopus tropicalis OX=8364 GN=EEF1AKMT2 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.8 0.0 1.4e-05 0.067 114 154 .. 131 174 .. 46 178 .. 0.62
Alignments for each domain:
== domain 1 score: 12.8 bits; conditional E-value: 1.4e-05
HC--SS-EEEEEE--SS--G...GGHHHHHHHEEEEEEEEEEE- CS
TRM 114 laekkkrfdviDlDPfGspa...pfldsavqsvkekglLlvTaT 154
+ k +fd++ lDP G++ +++ s +q++k +gl+++T+
tr|F6ZI67|F6ZI67_XENTR 131 VCLDKGTFDAVSLDPTGATEkreQYVRSLCQALKAQGLFIITSC 174
2257889**********9752337*****************975 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (376 nodes)
Target sequences: 24182 (11782085 residues searched)
Passed MSV filter: 739 (0.0305599); expected 483.6 (0.02)
Passed bias filter: 524 (0.021669); expected 483.6 (0.02)
Passed Vit filter: 41 (0.00169548); expected 24.2 (0.001)
Passed Fwd filter: 5 (0.000206765); expected 0.2 (1e-05)
Initial search space (Z): 24182 [actual number of targets]
Domain search space (domZ): 5 [number of targets reported over threshold]
# CPU time: 0.30u 0.01s 00:00:00.31 Elapsed: 00:00:00.10
# Mc/sec: 44300.64
//
[ok]