# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TRM13.hmm.txt # target sequence database: proteomes/Caenorhabditis_elegans.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TRM13 [M=262] Accession: PF05206.13 Description: Methyltransferase TRM13 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.4e-50 170.5 0.0 1.9e-47 162.1 0.0 2.5 1 tr|Q9XW93|Q9XW93_CAEEL Uncharacterized protein OS=Caenorhabd 0.00036 20.3 0.1 0.035 13.8 0.1 2.3 2 tr|Q93574|Q93574_CAEEL Uncharacterized protein OS=Caenorhabd Domain annotation for each sequence (and alignments): >> tr|Q9XW93|Q9XW93_CAEEL Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=CELE_Y49A3A.3 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 162.1 0.0 1.9e-51 1.9e-47 2 261 .. 159 388 .. 158 389 .. 0.92 Alignments for each domain: == domain 1 score: 162.1 bits; conditional E-value: 1.9e-51 TRM13 2 qqsslignleelkll..ekssayvEfGaGkgelsryvnqaleedkkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLn 86 q ss++g++e+++ll ++s++ E+GaGkg+l+ ++ +a+ n +y+L+dr+ r+k+D+ +++ +l +kR + I++++ tr|Q9XW93|Q9XW93_CAEEL 159 QISSILGHIESTGLLptCSKSCMFELGAGKGQLAYWISKAA-----PNGNYILMDRSGSRNKFDTAAFRENPNLSMKRFRCSIEHMD 240 789***********9777899*******************9.....566****************98888889************** PP TRM13 87 lsaleelekkkkvvavsKHLCGaATDLtLrcllnsekaskkakleglliAlCChhvCswkeyvnkeyleelgitke.efqiltkmvS 172 ls++ el++++k++a+ KH+CG ATD +r+l+ns + ++++l+ CChh +++ ey ++ +le++++++e +f++l +++S tr|Q9XW93|Q9XW93_CAEEL 241 LSKIDELKNSEKILAICKHFCGSATDAGIRSLMNSGLQ-----FNAALLIPCCHHKSRFAEYGGHDFLEKWEMNDEaSFAALRYIAS 322 **********************************9995.....8899999************************************* PP TRM13 173 WavsgkrkseaeeedekeekekeekkeeeeseeekksklsseereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlL 259 +a++g d + e + + s++ e+G++ak ++++gR+ +l++ gf++++v+Yv++evs+En+l+ tr|Q9XW93|Q9XW93_CAEEL 323 FATNGAV-------D---------T----E---ATEGWKSIHPPLELGRRAKAILEIGRAIWLESVGFKTRVVEYVPPEVSPENLLI 386 *****99.......1.........1....1...1222335667789***************************************99 PP TRM13 260 la 261 la tr|Q9XW93|Q9XW93_CAEEL 387 LA 388 87 PP >> tr|Q93574|Q93574_CAEEL Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=CELE_F25H2.12 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.8 0.1 3.5e-06 0.035 8 150 .. 137 287 .. 131 314 .. 0.62 2 ! 4.1 0.0 0.0032 32 227 261 .. 443 476 .. 438 477 .. 0.91 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 3.5e-06 TRM13 8 gnleelkllekss.....ayvEfGaGkgelsryvnqaleed.............kkenskyvLidrasnrlkaDrklrkdeselaik 76 + +++ ++++k+s +v++GaG g+lsr++ + + ++ + +L+d a+ ++ + k + + ++ tr|Q93574|Q93574_CAEEL 137 ELISQIQIFQKDSadpidSLVDIGAGIGHLSRMISIHNNISvmavegnqqftlaANSLDEKLLLDSAKIGSRIENFNVKSTP-IRYT 222 55566666655555555589**************986555566755556665555555556666666666666555555542.4444 PP TRM13 77 RlkidIkdLnlsaleelekkkkvvavsKHLCGaATDLtLrcllnsekaskkakleglliAlCChhv.Cswkeyvn 150 ++ L+++ + + ++ + v+ H CG L+ +sek ++l++ CC h + +++ tr|Q93574|Q93574_CAEEL 223 NFVTEDLALKIDDFAV----NSAILVGLHCCGDFSSTILKVFQKSEK------SKALVLFGCCYHKeFQCFHFLR 287 4444444455555655....68899*******766666666655555......4678888888764156666665 PP == domain 2 score: 4.1 bits; conditional E-value: 0.0032 TRM13 227 idegRllalkekgfeaelvkYvekevslEnvlLla 261 id R++ l+e+g ++++v e+++s+ n++++a tr|Q93574|Q93574_CAEEL 443 ID-DRVELLRENGINSRVVPLFEPSISPRNLAIIA 476 44.59****************************98 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (262 nodes) Target sequences: 20008 (8229220 residues searched) Passed MSV filter: 1492 (0.0745702); expected 400.2 (0.02) Passed bias filter: 556 (0.0277889); expected 400.2 (0.02) Passed Vit filter: 50 (0.002499); expected 20.0 (0.001) Passed Fwd filter: 2 (9.996e-05); expected 0.2 (1e-05) Initial search space (Z): 20008 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.22u 0.01s 00:00:00.23 Elapsed: 00:00:00.08 # Mc/sec: 26950.70 // [ok]