# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TRM13.hmm.txt # target sequence database: proteomes/Macaca_mulatta.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TRM13 [M=262] Accession: PF05206.13 Description: Methyltransferase TRM13 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.3e-92 310.3 0.1 2.2e-92 309.6 0.1 1.3 1 tr|F6YWH7|F6YWH7_MACMU tRNA guanosine-2'-O-methyltransf 0.00061 19.6 6.0 0.21 11.3 1.2 2.8 3 tr|A0A1D5Q1H2|A0A1D5Q1H2_MACMU Glutathione S-transferase C-term ------ inclusion threshold ------ 0.036 13.8 0.0 5.1 6.8 0.0 2.2 2 tr|F6UBC5|F6UBC5_MACMU Protein RRNAD1 isoform 1 OS=Maca Domain annotation for each sequence (and alignments): >> tr|F6YWH7|F6YWH7_MACMU tRNA guanosine-2'-O-methyltransferase TRM13 homolog OS=Macaca mulatta OX=9544 GN=TRMT13 PE=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 309.6 0.1 3.1e-96 2.2e-92 1 261 [. 165 469 .. 165 470 .. 0.96 Alignments for each domain: == domain 1 score: 309.6 bits; conditional E-value: 3.1e-96 TRM13 1 lqqsslignleelkllekssayvEfGaGkgelsryvnqaleedkkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLnl 87 +qq+s++gn+e+lkll +++++vEfGaGkg+ls++v+ al+++ e+++++L+++ ++r+k+D k+rk++s +++Rl+idI++L+l tr|F6YWH7|F6YWH7_MACMU 165 KQQASILGNIEKLKLLGPRRCFVEFGAGKGKLSHWVDIALKDA--EKVHFILVEKVTTRFKVDGKHRKKNS--VFERLQIDIQHLCL 247 69**************************************777..9************************6..************** PP TRM13 88 saleele.kkkkvvavsKHLCGaATDLtLrcllnsekask....................................kakleglliAl 137 +++++l+ k +vv+++KHLCG+ATDL+Lrcl+++++as ++ ++g++iAl tr|F6YWH7|F6YWH7_MACMU 248 NKIPVLReGKLPVVGIGKHLCGMATDLALRCLIETYAASFeerneeplakrikndktekeiytlakegnaknvpekWNPVAGIVIAL 334 *******999***************************9999********************************************** PP TRM13 138 CChhvCswkeyvnkeyleelgitkeefqiltkmvSWavsgkrkse...........aeeedekeekekeekkeeeeseeekksklss 213 CChh+C+w++yv+key+++lg+ + ef+++++m+SWa++g+rk++ ++++d +ee+++ + ++++ ++ + ls+ tr|F6YWH7|F6YWH7_MACMU 335 CCHHRCDWRHYVGKEYFRALGLGAVEFHYFQRMSSWATCGMRKTSletsnsttkrqDNQNDDSEEHDDGGYRITDDGANSLPGLLSV 421 ******************************************888999999998876666667777777889999999********* PP TRM13 214 eereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlLla 261 ee+++iG+ +k lid+gR+++l++kgf+++l++Y+++ vslEnvlL+a tr|F6YWH7|F6YWH7_MACMU 422 EEKKKIGHLCKLLIDQGRIQYLQQKGFSPALQYYTDPLVSLENVLLTA 469 **********************************************87 PP >> tr|A0A1D5Q1H2|A0A1D5Q1H2_MACMU Glutathione S-transferase C-terminal domain containing OS=Macaca mulatta OX=9544 GN=G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.2 0.74 5.3e+03 127 174 .. 97 147 .. 87 157 .. 0.71 2 ! 11.3 1.2 3e-05 0.21 75 169 .. 478 572 .. 436 581 .. 0.71 3 ! 10.6 0.0 5.1e-05 0.36 214 260 .. 583 629 .. 547 631 .. 0.89 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 0.74 TRM13 127 kakleglliAlCChhvCswkeyvn....keyleelgitkeefqiltkmvSWa 174 +++++ + +A+ +h+ + + y ke+le lg++k+ +++ +++ W tr|A0A1D5Q1H2|A0A1D5Q1H2_MACMU 97 SDNFCRAGLAVVLRHIIQKS-YEAdplkKELLELLGFKKTCLKACAEVSQWT 147 46777777788888887654.4333666888888999999999988888885 PP == domain 2 score: 11.3 bits; conditional E-value: 3e-05 TRM13 75 ikRlkidIkdLnlsaleelekkkkv......vavsKHLCGaATDLtLrcllnsekaskkakleglliAlCChhvCswke 147 + R k +L ls++ ++ + ++ ++v+ H CG+ATD+ ++ +++++++ ++ CC + + tr|A0A1D5Q1H2|A0A1D5Q1H2_MACMU 478 LIRAKKRSDELGLSNIWFIQANMEYftgmfnIGVALHACGVATDMVIEHCIKTRAS--------FVTCPCCYGFIQNTS 548 5555555566666666666645555566666999*************999988774........566667765555544 PP TRM13 148 yvn..keyleelgitkeefqiltk 169 n k+ ++ ++++e il++ tr|A0A1D5Q1H2|A0A1D5Q1H2_MACMU 549 KFNfpKSEQFKKTLSYKEHMILCR 572 444442223345555555555555 PP == domain 3 score: 10.6 bits; conditional E-value: 5.1e-05 TRM13 214 eereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlLl 260 +r+ iG+++ l+d R+ a +e g++++++ +++ s+ n +++ tr|A0A1D5Q1H2|A0A1D5Q1H2_MACMU 583 PQRRLIGKQCMCLVDLDRARAAEECGYSVQVISMEPESCSPKNNMIV 629 47999*************************************99886 PP >> tr|F6UBC5|F6UBC5_MACMU Protein RRNAD1 isoform 1 OS=Macaca mulatta OX=9544 GN=RRNAD1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.0031 22 9 55 .. 144 191 .. 138 214 .. 0.76 2 ? 6.8 0.0 0.00073 5.1 226 261 .. 423 458 .. 417 459 .. 0.90 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.0031 TRM13 9 nleelkllekssayvEfGaGkgelsryvnqaleed.kkenskyvLidr 55 +++l +++ +++v+ G+G+g+lsr+++ l k+ + L++r tr|F6UBC5|F6UBC5_MACMU 144 LVKKLSDFTGCTQVVDVGSGQGHLSRFMALGLGLMvKSIEGDQRLVER 191 6778888899999**************987554332344445555655 PP == domain 2 score: 6.8 bits; conditional E-value: 0.00073 TRM13 226 lidegRllalkekgfeaelvkYvekevslEnvlLla 261 li Rll+l+e+gf+ael +e+s+ n++L+a tr|F6UBC5|F6UBC5_MACMU 423 LILLDRLLYLQEQGFHAELLPIFSPELSPRNLVLVA 458 66667*****************************98 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (262 nodes) Target sequences: 21211 (10888574 residues searched) Passed MSV filter: 1499 (0.0706709); expected 424.2 (0.02) Passed bias filter: 646 (0.0304559); expected 424.2 (0.02) Passed Vit filter: 50 (0.00235727); expected 21.2 (0.001) Passed Fwd filter: 3 (0.000141436); expected 0.2 (1e-05) Initial search space (Z): 21211 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.28u 0.01s 00:00:00.29 Elapsed: 00:00:00.09 # Mc/sec: 31697.85 // [ok]