# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TRM13.hmm.txt # target sequence database: proteomes/Monodelphis_domestica.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TRM13 [M=262] Accession: PF05206.13 Description: Methyltransferase TRM13 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.2e-92 307.7 0.8 1.1e-91 307.2 0.8 1.2 1 tr|F7B009|F7B009_MONDO tRNA methyltransferase 13 homolog OS= 2.3e-06 27.6 0.4 0.031 14.0 0.0 2.6 2 tr|F6ZAN7|F6ZAN7_MONDO Glutathione S-transferase C-terminal ------ inclusion threshold ------ 0.15 11.8 0.0 8.6 6.0 0.0 2.2 2 tr|F7FVV1|F7FVV1_MONDO Ribosomal RNA adenine dimethylase dom 0.34 10.6 4.0 0.43 10.3 4.0 1.3 1 tr|K7E1L1|K7E1L1_MONDO Uncharacterized protein OS=Monodelphi Domain annotation for each sequence (and alignments): >> tr|F7B009|F7B009_MONDO tRNA methyltransferase 13 homolog OS=Monodelphis domestica OX=13616 GN=TRMT13 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 307.2 0.8 2.2e-95 1.1e-91 1 261 [. 169 472 .. 169 473 .. 0.95 Alignments for each domain: == domain 1 score: 307.2 bits; conditional E-value: 2.2e-95 TRM13 1 lqqsslignleelkllekssayvEfGaGkgelsryvnqaleedkkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLnl 87 +qq+s++gn+e+l+ll +++++vEfGaGkg+ls++v+ al+e+ e++ ++L++r ++r+k+D k++k++s +++Rl+idI++L+l tr|F7B009|F7B009_MONDO 169 KQQASILGNIERLNLLGPRRCFVEFGAGKGKLSHWVDIALQEA--EKVYFFLVERVTTRFKVDGKHKKKNS--VFERLQIDIQHLCL 251 69**************************************888..99***********************6..************** PP TRM13 88 saleele.kkkkvvavsKHLCGaATDLtLrcllnsekask....................................kakleglliAl 137 s++++l +k +vv+++KHLCG+ATDL+Lrcl++++ a+ + ++g++iAl tr|F7B009|F7B009_MONDO 252 SKIPVLIkEKLPVVGIGKHLCGVATDLALRCLVETYPAKCkeineepeakrikndktdadndtlvnegskkneldqRIPVAGIVIAL 338 *****99899*************************9987689********************************99899******** PP TRM13 138 CChhvCswkeyvnkeyleelgitkeefqiltkmvSWavsgkrkse..........aeeedekeekekeekkeeeeseeekksklsse 214 CChh+C+w++yv+ke++++lg+ +ef+++++m+SWa++g+r+++ +++ +++e e+e ++++++ e+ + l++e tr|F7B009|F7B009_MONDO 339 CCHHRCDWRHYVGKEFFKTLGLGPQEFNYFQRMSSWATCGMRETTmetseinikkRDDQASDNEDEHEGFRKTDDNPEGLSRLLTVE 425 ******************************************88899***9987644555566677777799999999999****** PP TRM13 215 ereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlLla 261 er++iG+ +k lid+gR+++l++kg++a+l++Y+++ vslEnvlL+a tr|F7B009|F7B009_MONDO 426 ERKNIGHLCKLLIDQGRIQYLQQKGYNASLQYYTDSFVSLENVLLTA 472 *********************************************87 PP >> tr|F6ZAN7|F6ZAN7_MONDO Glutathione S-transferase C-terminal domain containing OS=Monodelphis domestica OX=13616 GN=G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 11.0 0.2 5.1e-05 0.27 73 123 .. 464 520 .. 423 535 .. 0.79 2 ! 14.0 0.0 5.8e-06 0.031 215 260 .. 572 617 .. 553 619 .. 0.91 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 5.1e-05 TRM13 73 laikRlkidIkdLnlsaleelekkkkv......vavsKHLCGaATDLtLrcllnsek 123 l + R k dL l ++ ++ + + ++v+ H CG+ATD+ ++ +++ ++ tr|F6ZAN7|F6ZAN7_MONDO 464 LSLVRAKKRSDDLGLTNIWFIQANLDYftgkfnIGVALHACGVATDMVIEHCTKARA 520 5566666666777777776666444444555559**************998887655 PP == domain 2 score: 14.0 bits; conditional E-value: 5.8e-06 TRM13 215 ereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlLl 260 er+ iG+++ l+d R++a +e+g++++l+ +++ s+ n +++ tr|F6ZAN7|F6ZAN7_MONDO 572 ERRLIGKQCMCLVDLDRAWAAEERGYSVQLISMEPESCSPKNNMIV 617 7899*************************************99986 PP >> tr|F7FVV1|F7FVV1_MONDO Ribosomal RNA adenine dimethylase domain containing 1 OS=Monodelphis domestica OX=13616 GN=RR # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.0 0.0 0.0016 8.6 8 57 .. 143 193 .. 138 213 .. 0.79 2 ? 3.5 0.0 0.01 53 226 261 .. 429 464 .. 424 465 .. 0.90 Alignments for each domain: == domain 1 score: 6.0 bits; conditional E-value: 0.0016 TRM13 8 gnleelkllekssayvEfGaGkgelsryvnqaleed.kkenskyvLidras 57 + +++l +l++ +++v+ G+G+g+l+r+++ l + + ++ L++ra+ tr|F7FVV1|F7FVV1_MONDO 143 ELVKKLSDLTSCNQVVDVGSGQGHLTRFLALGLGLSvTGIEKDRKLVERAQ 193 5678999999******************99866555344555566666665 PP == domain 2 score: 3.5 bits; conditional E-value: 0.01 TRM13 226 lidegRllalkekgfeaelvkYvekevslEnvlLla 261 li Rll+l+e+g +ael +e+s+ n++L+a tr|F7FVV1|F7FVV1_MONDO 429 LILLDRLLFLQEQGCHAELLPVFRPELSPRNLVLVA 464 56667*****************************98 PP >> tr|K7E1L1|K7E1L1_MONDO Uncharacterized protein OS=Monodelphis domestica OX=13616 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.3 4.0 8.1e-05 0.43 179 229 .. 67 117 .. 37 126 .. 0.67 Alignments for each domain: == domain 1 score: 10.3 bits; conditional E-value: 8.1e-05 TRM13 179 rkseaeeedekeekekeekkeeeeseeekksklsseereeiGlkakrlide 229 +++e+eee+e+ee+e+ee++eeee+eee+ ++l ++ ++++ +++ tr|K7E1L1|K7E1L1_MONDO 67 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEELRHHTKRNYQEIFPDILES 117 222244445555556666666777777778888888887766655555555 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (262 nodes) Target sequences: 21272 (11266248 residues searched) Passed MSV filter: 1676 (0.078789); expected 425.4 (0.02) Passed bias filter: 622 (0.0292403); expected 425.4 (0.02) Passed Vit filter: 74 (0.00347875); expected 21.3 (0.001) Passed Fwd filter: 12 (0.000564122); expected 0.2 (1e-05) Initial search space (Z): 21272 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.32u 0.01s 00:00:00.33 Elapsed: 00:00:00.11 # Mc/sec: 26834.15 // [ok]