# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TRM13.hmm.txt # target sequence database: proteomes/Nematostella_vectensis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TRM13 [M=262] Accession: PF05206.13 Description: Methyltransferase TRM13 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.8e-93 311.9 0.0 6.9e-93 311.4 0.0 1.2 1 tr|A7RR85|A7RR85_NEMVE Predicted protein OS=Nematostella vec ------ inclusion threshold ------ 0.12 12.3 0.1 0.31 11.0 0.0 1.6 2 tr|A7S108|A7S108_NEMVE Predicted protein OS=Nematostella vec Domain annotation for each sequence (and alignments): >> tr|A7RR85|A7RR85_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g90494 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 311.4 0.0 5.6e-97 6.9e-93 1 261 [. 161 448 .. 161 449 .. 0.95 Alignments for each domain: == domain 1 score: 311.4 bits; conditional E-value: 5.6e-97 TRM13 1 lqqsslignleelkllekssayvEfGaGkgelsryvnqaleedkkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLnl 87 +qq+sl+gn+e+l+ll+++++y+EfGaGkg+ls++v+qa+ e n++yvLidrasnr+k+D+++++ ++ + +kR+ +dI++Lnl tr|A7RR85|A7RR85_NEMVE 161 KQQASLVGNMERLGLLQPDTVYLEFGAGKGKLSHWVQQAHPEG--GNVEYVLIDRASNRYKFDSCHKRGDNGPDFKRVLLDIEHLNL 245 69**************************************988..****************************************** PP TRM13 88 saleele.kkkkvvavsKHLCGaATD..LtLrcllnsekask.......................kakleglliAlCChhvCswkey 148 +l++l k++++vavsKHLCG+AT LtLrcll++ + s+ ++ g+++AlCChh+C w +y tr|A7RR85|A7RR85_NEMVE 246 GELPHLGdKTRRIVAVSKHLCGTATGryLTLRCLLDTLHGSSatepdstlkseqkdakrrkldaaGPSVIGIVVALCCHHQCYWPHY 332 ******9999***************999***********9999*********************99********************* PP TRM13 149 vnkeyleelgitkeefqiltkmvSWavsgkrkse.....aeeedekeekekeekkeeeeseeekksklsseereeiGlkakrlideg 230 v++ +le+lgit +ef++l++m+SWa++g+r+ + ae+++++e+ e+++++ +++s+++ +ls+++reeiG+++krl+d+g tr|A7RR85|A7RR85_NEMVE 333 VGRPFLESLGITPQEFHLLCCMSSWATCGMRPPQgsskeAEHCNTDESGETDDDNGVDGSDKG--LGLSIADREEIGRQCKRLLDAG 417 *******************************98888777677777777777777777775554..57******************** PP TRM13 231 RllalkekgfeaelvkYvekevslEnvlLla 261 R+++l+ekgf+++l++Yv+++vslEnv+Lla tr|A7RR85|A7RR85_NEMVE 418 RVWYLREKGFNTSLAYYVDSSVSLENVVLLA 448 *****************************98 PP >> tr|A7S108|A7S108_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g242091 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 2.5e-05 0.31 16 43 .. 46 73 .. 32 91 .. 0.79 2 ? -2.0 0.1 0.23 2.8e+03 158 186 .. 209 238 .. 199 265 .. 0.63 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 2.5e-05 TRM13 16 lekssayvEfGaGkgelsryvnqaleed 43 +++ +++E+GaG g+++r+v+++le++ tr|A7S108|A7S108_NEMVE 46 CNREFKILELGAGTGKFTRVVMEVLEKN 73 478899******************9887 PP == domain 2 score: -2.0 bits; conditional E-value: 0.23 TRM13 158 gitke.efqiltkmvSWavsgkrkseaeee 186 +++++ f++l + +S a +++++ea + tr|A7S108|A7S108_NEMVE 209 NVNTQsMFSYLLSYSSVASLSEEEKEAFKL 238 555555788888888877777765553332 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (262 nodes) Target sequences: 24428 (8257945 residues searched) Passed MSV filter: 1347 (0.0551416); expected 488.6 (0.02) Passed bias filter: 527 (0.0215736); expected 488.6 (0.02) Passed Vit filter: 36 (0.00147372); expected 24.4 (0.001) Passed Fwd filter: 3 (0.00012281); expected 0.2 (1e-05) Initial search space (Z): 24428 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.20u 0.01s 00:00:00.21 Elapsed: 00:00:00.07 # Mc/sec: 30908.31 // [ok]