# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/TRM13.hmm.txt # target sequence database: proteomes/Pan_troglodytes.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: TRM13 [M=262] Accession: PF05206.13 Description: Methyltransferase TRM13 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.2e-92 308.7 0.2 6.9e-92 308.0 0.2 1.3 1 tr|H2PZH2|H2PZH2_PANTR Coiled-coil domain containing 76 0.0007 19.6 6.0 0.22 11.4 1.1 2.8 3 tr|H2R3L6|H2R3L6_PANTR GSTCD isoform 1 OS=Pan troglodyt ------ inclusion threshold ------ 0.044 13.7 0.0 6 6.7 0.0 2.2 2 tr|A0A2I3RRF6|A0A2I3RRF6_PANTR Ribosomal RNA adenine dimethylas Domain annotation for each sequence (and alignments): >> tr|H2PZH2|H2PZH2_PANTR Coiled-coil domain containing 76 OS=Pan troglodytes OX=9598 GN=TRMT13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 308.0 0.2 9e-96 6.9e-92 1 261 [. 165 469 .. 165 470 .. 0.96 Alignments for each domain: == domain 1 score: 308.0 bits; conditional E-value: 9e-96 TRM13 1 lqqsslignleelkllekssayvEfGaGkgelsryvnqaleedkkenskyvLidrasnrlkaDrklrkdeselaikRlkidIkdLnl 87 +qq+s++gn+e+lkll +++++vEfGaGkg+ls++v+ al+++ e+++++L+++ ++r+k+D k+rk++s +++Rl+idI++L+l tr|H2PZH2|H2PZH2_PANTR 165 KQQASILGNIENLKLLGPRRCFVEFGAGKGKLSHWVDIALKDA--EKVHFILVEKVTTRFKVDGKHRKKNS--VFERLQIDIQHLCL 247 69**************************************777..9************************6..************** PP TRM13 88 saleele.kkkkvvavsKHLCGaATDLtLrcllnsekask....................................kakleglliAl 137 +++++l+ +k +vv+++KHLCG+ATDL+Lrcl+++++as ++ ++g++iAl tr|H2PZH2|H2PZH2_PANTR 248 NKIPVLReEKLPVVGIGKHLCGMATDLALRCLVETYAASFeerneeplakrikndktekeiytlakegneknvpekWNPVAGIVIAL 334 *******999***************************9999********************************************** PP TRM13 138 CChhvCswkeyvnkeyleelgitkeefqiltkmvSWavsgkrkse...........aeeedekeekekeekkeeeeseeekksklss 213 CChh+C+w++yv+key+++lg+ + ef+++++m+SWa++g+rk++ ++++d +ee+++ + ++++ + + ls+ tr|H2PZH2|H2PZH2_PANTR 335 CCHHRCDWRHYVGKEYFRALGLGAVEFHYFQRMSSWATCGMRKTSletsdsttkrqDNQNDDSEEHDDGGYRITDDGADCLPGLLSV 421 ******************************************888999999998776666667777777778999999999****** PP TRM13 214 eereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlLla 261 ee+++iG+ +k lid+gR+++l++kgf+++l++Y+++ vslEnvlL+a tr|H2PZH2|H2PZH2_PANTR 422 EEKKKIGHLCKLLIDQGRIQYLQQKGFSPALQYYTDPLVSLENVLLTA 469 **********************************************87 PP >> tr|H2R3L6|H2R3L6_PANTR GSTCD isoform 1 OS=Pan troglodytes OX=9598 GN=GSTCD PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.1 0.2 0.76 5.9e+03 127 174 .. 97 147 .. 87 155 .. 0.70 2 ! 11.4 1.1 2.8e-05 0.22 75 169 .. 478 572 .. 436 581 .. 0.71 3 ! 10.3 0.0 6.1e-05 0.46 215 260 .. 584 629 .. 563 631 .. 0.92 Alignments for each domain: == domain 1 score: -3.1 bits; conditional E-value: 0.76 TRM13 127 kakleglliAlCChhvCswkeyvn....keyleelgitkeefqiltkmvSWa 174 +++++ + +A+ +h+ + + y ke+le lg++k+ +++ +++ W tr|H2R3L6|H2R3L6_PANTR 97 SDNFCRAGLAVVLRHIIQKS-YEAdplkKELLELLGFKKTCLKACAEVSQWT 147 46777777788888887654.4333676888888999999999988888885 PP == domain 2 score: 11.4 bits; conditional E-value: 2.8e-05 TRM13 75 ikRlkidIkdLnlsaleelekkkkv......vavsKHLCGaATDLtLrcllnsekaskkakleglliAlCChhvCswkeyvn..key 153 + R k +L ls++ ++ + ++ ++v+ H CG+ATD+ ++ +++++++ ++ CC + + n k+ tr|H2R3L6|H2R3L6_PANTR 478 LIRAKKRSDELGLSNIWFIQANMEYftgmfnIGVALHACGVATDMVIEHCIKTRAS--------FVTCPCCYGFIQNTSKFNfpKSE 556 5555555566666666666645555566666999*************999988774........56666776555554444444222 PP TRM13 154 leelgitkeefqiltk 169 ++ ++++e il++ tr|H2R3L6|H2R3L6_PANTR 557 QFKKTLSYKEHMILCR 572 3345555555555555 PP == domain 3 score: 10.3 bits; conditional E-value: 6.1e-05 TRM13 215 ereeiGlkakrlidegRllalkekgfeaelvkYvekevslEnvlLl 260 +r+ iG+++ l+d R+ a +e g++++++ +++ s+ n +++ tr|H2R3L6|H2R3L6_PANTR 584 QRRLIGKQCMCLVDLDRARAAEECGYSVQVISMEPESCSPKNNMIV 629 7999*************************************99886 PP >> tr|A0A2I3RRF6|A0A2I3RRF6_PANTR Ribosomal RNA adenine dimethylase domain containing 1 OS=Pan troglodytes OX=9598 GN=R # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 4.7 0.0 0.0031 24 9 55 .. 144 191 .. 138 214 .. 0.76 2 ? 6.7 0.0 0.00079 6 226 261 .. 423 458 .. 417 459 .. 0.90 Alignments for each domain: == domain 1 score: 4.7 bits; conditional E-value: 0.0031 TRM13 9 nleelkllekssayvEfGaGkgelsryvnqaleed.kkenskyvLidr 55 +++l +++ +++v+ G+G+g+lsr+++ l k+ + L++r tr|A0A2I3RRF6|A0A2I3RRF6_PANTR 144 LVKKLSDFTGCTQVVDVGSGQGHLSRFMALGLGLMvKSIEGDQRLVER 191 6778888899999**************987554332344445555655 PP == domain 2 score: 6.7 bits; conditional E-value: 0.00079 TRM13 226 lidegRllalkekgfeaelvkYvekevslEnvlLla 261 li Rll+l+e+gf+ael +++s+ n++L+a tr|A0A2I3RRF6|A0A2I3RRF6_PANTR 423 LILLDRLLYLQEQGFHAELLPIFSPQLSPRNLVLVA 458 66667*****************************98 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (262 nodes) Target sequences: 23008 (11942255 residues searched) Passed MSV filter: 1659 (0.0721054); expected 460.2 (0.02) Passed bias filter: 701 (0.0304677); expected 460.2 (0.02) Passed Vit filter: 66 (0.00286857); expected 23.0 (0.001) Passed Fwd filter: 3 (0.000130389); expected 0.2 (1e-05) Initial search space (Z): 23008 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.32u 0.01s 00:00:00.33 Elapsed: 00:00:00.10 # Mc/sec: 31288.71 // [ok]